Clinical trials: Cholecystitis; Gallstone
Gall Stone, Gall Stones, Common Bile Duct
Influence of Gut Microbiome in Gallstone Disease
The goal of this prospective observational study is to explore the role of the gut microbiome in patients with gallstone disease.
- Conditions
- Gall Stone, Gall Stones, Common Bile Duct, Pancreatitis, Acute Cholecystitis
- Trial name
- NCT05732480
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Atelectasis, Postoperative, Cholecystitis; Gallstone
Ultrasound for Postop Lung Issues in Low-Flow Anesthesia
Detecting possible atelectasis and other respiratory problems that may develop immediately after extubation via lung ultrasonography can reduce pulmonary complications by performing necessary interventions such as oxygen support…
- Conditions
- Atelectasis, Postoperative, Cholecystitis; Gallstone, Pulmonary Atelectasis
- Trial name
- NCT06824506
- Testing
- No-intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Acute Cholecystitis
EUS-guided Gallbladder Drainage Instead of Laparoscopic Cholecystectomy for Acute Cholecystitis. A Feasibility Study.
To evaluate the feasibility of performing EGBD as a treatment of acute calculous cholecystitis in patients that are indicated for laparoscopic cholecystectomy.
- Trial name
- EGDB (NCT04197908)
- Testing
- EUS-guided gallbladder drainage (EGBD)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Cholecystectomy, Laparoscopic, Cholecystitis
Clipless Versus Conventional Laparoscopic Cholecystectomy Using Harmonic Scalpel
This randomized controlled trial compares the operative outcomes of clipless laparoscopic cholecystectomy using a harmonic scalpel (HS) versus conventional clip-based laparoscopic cholecystectomy (CLC) in patients with gallstone…
- Conditions
- Cholecystectomy, Laparoscopic, Cholecystitis, Gall Stones (& [Calculus - Gall Bladder])
- Trial name
- NCT07473388
- Testing
- Clipless Laparoscopic Cholecystectomy with Harmonic Scalpel, Conventional Laparoscopic Cholecystectomy
- Where
- Pakistan
- Volunteers
- 158 people
- Sponsor
- Services Hospital, Lahore
Gallbladder Stone
A Strategy for Gallstone Expulsion Through Dietary Therapy
This study is a double-blind, prospective, single-center controlled trial conducted at a tertiary hospital, aiming to determine whether dietary therapy can effectively expel gallstones.
- Trial name
- NCT06699030
- Testing
- Functional fatty acids
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Cholecystitis; Gallstone, Cholecystolithiasis
Effect of TENS on Patient Outcomes After Laparoscopic Cholecystectomy
The aim of this study is to evaluate the effect of TENS (Transcutaneous Electrical Nerve Stimulation) on patient outcomes after laparoscopic cholecystectomy.
- Trial name
- TENS (NCT05962853)
- Testing
- Experimental group (Transcutaneous Electrical Nerve Stimulation)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Cukurova University
Acute Cholecystitis
Early Versus Delayed Laparoscopic Cholecystectomy for Acute Cholecystitis
The goal of this clinical trial is to learn if performing gallbladder surgery early is as safe and effective as delaying it for people with acute cholecystitis (a sudden gallbladder infection).
- Trial name
- EDLC-AC (NCT07101315)
- Testing
- Laparoscopic Cholecystectomy
- Where
- 2 sites in Yemen
- Volunteers
- 81 people
- Sponsor
- Sana'a University
Gall Stone, Common Bile Duct Calculi
Laparoendoscopic Rendezvous for Concomitant Gall Bladder Stones and Common Bile Duct Stones
Chronic calculous cholecystitis in pediatric patients leads to choledocholithiasis in about 12% of cases. These patients require removal of stones from the common bile duct.
- Conditions
- Gall Stone, Common Bile Duct Calculi, Cholecystitis, Chronic, Choledocholithiasis
- Trial name
- LERV (NCT07008170)
- Testing
- Laparoendoscopic rendezvous
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Minia University
Cholecystitis; Gallstone, Cholecystolithiasis
A (5-5-5-8) Technique for Laparoscopic Cholecystectomy
The aim of this current study is to investigate the effectiveness and safety of a novel technique which is the 5-5-5-8 where the camera port is 5 mm.
- Conditions
- Cholecystitis; Gallstone, Cholecystolithiasis, Cholecystitis, Chronic
- Trial name
- NCT06045546
- Testing
- 5-5-5-8 technique, 10-10-5-5 technique
- Where
- Egypt
- Volunteers
- 524 people
- Sponsor
- ClinAmygate
Gallstone, Gallstone; Cholecystitis, Acute
Indocyanine Green Fluorescence During Fundus First Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is the routine method for managing gallstone disease. This is considered a safe procedure with low risk of severe complications.
- Trial name
- INFUNDUS (NCT06918210)
- Testing
- Indocyanine Green, Cholangiography
- Volunteers
- 294 people
- Sponsor
- Karolinska Institutet
Gall Stone, Gallbladder Inflammation
Benchmarks in Elective Laparoscopic Cholecystectomy
The aim of this observational cohort study is to define peri- and postoperative reference values for elective laparoscopic cholecystectomy, using the achievable benchmarks of care methodology (ABC™).
- Conditions
- Gall Stone, Gallbladder Inflammation, Gall Bladder Pain, Gallstone
- Trial name
- NCT06692517
- Testing
- Laparoscopic cholecystectomy
- Volunteers
- 60,000 people
- Sponsor
- Region Östergötland
Gallbladder, Gall Stones (&Amp; [Calculus - Gall Bladder])
Benchmarks in Acute Laparoscopic Cholecystectomy
The aim of this observational cohort study is to define peri- and postoperative reference values for acute laparoscopic cholecystectomy, using the achievable benchmarks of care methodology (ABC™).
- Conditions
- Gallbladder, Gall Stones (&Amp; [Calculus - Gall Bladder]), Gall Stone, Gallbladder Inflammation
- Trial name
- NCT06693076
- Testing
- Laparoscopic cholecystectomy
- Volunteers
- 40,000 people
- Sponsor
- Region Östergötland
Gall Stones (& [Calculus - Gall Bladder]), Cholecystitis
Laparoscopic Cholecystectomy Using Airseal in Children
The goal of this observational study is to compare the use of Airseal versus a standard insufflation, in children who underwent laparoscopic cholecystectomy, between January 2021 and December 2022.
- Conditions
- Gall Stones (& [Calculus - Gall Bladder]), Cholecystitis, Pancreatitis Due to Gallstones, Child, Only
- Trial name
- VBAS (NCT06734507)
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Destinval Christelle
Cholecystitis, Cholecystitis, Acute
EOIB for Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy, while less painful compared to conventional methods, is still a surgery that can cause significant pain for patients.
- Conditions
- Cholecystitis, Cholecystitis, Acute, Cholecystitis, Chronic, Cholecystitis; Gallstone
- Trial name
- NCT06656299
- Testing
- ultrasound guided external oblique intercostal plane block, Bupivacaine injection, paracetamol, tramadol, and ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Cholecystitis, Cholecystitis; Gallstone
Dutch Cholecystitis Snapshot Study
Background: Cholecystitis is treated by in various types of hospitals by different specialists, and treatment strategy is influenced by logistical and medical reasons and personal preference.
- Conditions
- Cholecystitis, Cholecystitis; Gallstone, Cholecystitis; Choledocholithiasis
- Trial name
- Dutch CHESS (NCT06349863)
- Where
- Netherlands
- Volunteers
- 3,000 people
- Sponsor
- St. Antonius Hospital
Cholecystectomy, Adults
ALgerian Cholecystectomy Outcomes and Determinants Study (AL-CODS)
Cholecystectomy, the surgical removal of the gallbladder, is a common procedure performed to treat benign gallbladder diseases such as cholelithiasis (gallstones), cholecystitis (inflammation of the gallbladder), and biliary…
- Conditions
- Cholecystectomy, Adults, Gall Stone, Polyps
- Trial name
- AL-CODS (NCT06481007)
- Volunteers
- 500 people
- Sponsor
- University of Oran 1
Gallstone Disease, Gallstone; Colic
A Randomized Controlled Trial Comparing Fat-free Versus Balanced (WHO) Diet in Gallstone Disease
The goal of this trial is to assess the effect on the quality of life (QoL) of recommending a fat-free diet versus a balanced WHO diet in symptomatic patients with gallstones and in patients undergoing cholecystectomy for…
- Conditions
- Gallstone Disease, Gallstone; Colic, Gallstone; Cholecystitis, Acute, Cholelithiases
- Trial name
- RADIGAL (NCT06405906)
- Testing
- Fat-free diet, Balanced WHO diet
- Where
- Greece
- Volunteers
- 242 people
- Sponsor
- University Hospital of Crete
Cholecystitis, Gallstones
Fluorescence Cholangiography During Cholecystectomy - a RCT
The primary objective is to compare the success rates of intraoperative fluorescent cholangiography using indocyanine green versus conventional X-ray cholangiography for the identification of bile duct anatomy during laparoscopic…
- Trial name
- NCT02344654
- Testing
- Indocyanine green, Near-infrared illumination, Urografin
- Volunteers
- 120 people
- Sponsor
- Hvidovre University Hospital
Cerebral Hypoperfusion, Cerebral Occlusion
Evaluation of Cerebral Blood Flow and Cerebral Oxygenation With Transcranial Doppler and NIRS in Laparoscopic Cholecystectomy Cases
The goal of this clinical trial is to test intracranial blood flow and cerebral oxygenisation changes in patients who have pneumoperitoneum in laparoscopic cholecystectomy procedure.
- Conditions
- Cerebral Hypoperfusion, Cerebral Occlusion, Cholecystitis; Gallstone, Cholecystitis/Cholelithiasis
- Trial name
- NIRS L/C (NCT06036498)
- Testing
- Near Infrared Spectrophotometry Device, Transcranial Doppler Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uludag University
Common Bile Duct Calculi, Acute; Cholecystitis, Choledocholithiasis
Modified Laparoscopic Transcystic Biliary Drainage in the Management of Cholecystocholedocholithiasis
The modified laparoscopic transcystic biliary drainage which we developed in the treatment of cholecystocholedocholithiasis has some advantages over conventional techniques.
- Conditions
- Common Bile Duct Calculi, Acute; Cholecystitis, Choledocholithiasis, Acute Cholecystitis With Obstruction, Acute Cholangitis
- Trial name
- NCT06011941
- Testing
- Modified laparoscopic transcystic biliary drainage
- Where
- China
- Volunteers
- 310 people
- Sponsor
- Peking University Third Hospital