Clinical trials: Cholecystitis
Cholecystitis, Acute
Laparoscopic Cholecystectomy or Conservative Treatment in the Acute Cholecystitis of Elderly Patients
Cholecystectomy is the only curative treatment for gallstone disease of acute calculous cholecystitis.The purpose of this study is to find the most effective treatment (laparoscopic cholecystectomy vs.
- Trial name
- NCT02972944
- Testing
- Laparoscopic cholecystectomy, Non-operative treatment
- Where
- Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Cholecystitis
Food Effect on the Bioavailability of 4-MUST, Tablets, 128 mg
Primary objective of the study: evaluation of the effect of food intake on the bioavailability of 4-MUST, tablets, 128 mg (Valenta Pharm JSC) after a single oral administration on an empty stomach and after a meal, at a dose of…
- Trial name
- NCT06342804
- Testing
- 4-MUST, 2 tablets, fasted, 4-MUST, 2 tablets, after meals
- Where
- Russia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Cholecystitis
Video Laryngeal Mask Versus Endotracheal Tube Undergoing Laparoscopic Cholecystectomy Surgery
The aim of this study is to investigate the effectiveness of using a video laryngeal mask for airway management in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT06502028
- Testing
- Video laryngeal mask airway, Endotracheal tube
- Where
- South Korea
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Cholecystitis, Acute
Benefits of Glycopyrrolate on Intubation With Rigid-videostylet (OptiScope®)
This study is intended to evaluate the efficacy and safety of glycopyrrolate as an antisialagogue prior to intubation with the rigid-videostylet(Optiscope®) in the general anesthesia settings.
- Trial name
- NCT03050242
- Testing
- Glycopyrrolate
- Where
- South Korea
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Eunah Cho, MD
Acute Cholecystitis, Chronic Cholecystitis
Evaluation of Closed-loop TIVA Propofol, Sufentanil and Ketamine Guided by BIS Monitor
The purpose of this study is to compare a closed-loop intravenous anesthetic using Bispectral Index as a feedback loop and a controller based on reinforcement learning to titrate dose and intravenous anesthetic that is manually…
- Trial name
- NCT01942356
- Testing
- TIVA - Hypotension, TIVA - Hypertension, TIVA - Bradycardia
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Acute Cholecystitis
Prolonged Versus Delayed Laparoscopic Cholecystectomy for Acute Cholecystitis
Gallbladder stone affects 10-15% of the adult population, and about 15-25% of these patients presented with acute cholecystitis (AC).
- Trial name
- NCT05736003
- Testing
- Laparoscopic cholecystectomy
- Where
- Egypt
- Volunteers
- 437 people, healthy volunteers welcome
- Sponsor
- South Valley University
Medical Education, Gamification
The Effectiveness of Gamification vs. Traditional Teaching in Undergraduate Medical Education
This study will evaluate the effectiveness of a gamification-based learning method (board game) versus traditional teaching (lecture) in enhancing the knowledge of acute cholecystitis and pancreatitis among medical students in…
- Trial name
- NCT06763627
- Testing
- Gamification ( Board game ), Traditional lecture-based teaching
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Iran University of Medical Sciences
Cholecystitis, Cholelithiasis
Feasibility and Utility of Artificial Intelligence (AI) / Machine Learning (ML) - Driven Advanced Intraoperative Visualization and Identification of Critical Anatomic Structures and Procedural Phases in Laparoscopic Cholecystectomy
The goal of this study is to evaluate the utility and efficacy of an artificial intelligence (AI) model at identifying structures and phases of surgery compared to traditional white light assessment by trained surgeons.
- Conditions
- Cholecystitis, Cholelithiasis, Biliary Dyskinesia
- Trial name
- NCT05775133
- Testing
- ICG
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Activ Surgical
Biliary Disease, Gallstone; Cholecystitis, Acute
Multicentric Point of Care UltraSound by Surgeons Trial
Acute gallbladder pathology and acute diverticulitis are common conditions met in emergency departments and comprise the bulk of admissions throughout general surgical calls.
- Conditions
- Biliary Disease, Gallstone; Cholecystitis, Acute, Diverticulitis, Colonic, Abscess Pelvic
- Trial name
- POCUSS (NCT02682368)
- Testing
- Point of Care Ultrasound by Surgeons (POCUSS), Radiology report, Surgery-Intra-operative findings
- Where
- 5 sites in Ireland, Italy and 2 more
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Connolly Hospital Blanchardstown
Cerebral Hypoperfusion, Cerebral Occlusion
Evaluation of Cerebral Blood Flow and Cerebral Oxygenation With Transcranial Doppler and NIRS in Laparoscopic Cholecystectomy Cases
The goal of this clinical trial is to test intracranial blood flow and cerebral oxygenisation changes in patients who have pneumoperitoneum in laparoscopic cholecystectomy procedure.
- Conditions
- Cerebral Hypoperfusion, Cerebral Occlusion, Cholecystitis; Gallstone, Cholecystitis/Cholelithiasis
- Trial name
- NIRS L/C (NCT06036498)
- Testing
- Near Infrared Spectrophotometry Device, Transcranial Doppler Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uludag University
Mirizzi Syndrome, Cholelithiasis
Treatment of Mirizzi Syndrome
Mirizzi syndrome is an infrequent complication of long-standing cholelithiasis. Extrinsic compression of the common hepatic duct is usually caused by an impacted stone in Hartmann's pouch or cystic duct resulting in the…
- Conditions
- Mirizzi Syndrome, Cholelithiasis, Acute Cholecystitis
- Trial name
- NCT04672902
- Testing
- Single-operator cholangioscopy guided electrohydraulic lithotripsy
- Where
- Mexico
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Tecnologico de Monterrey
Cholecystitis, Acute
The Role of Ultrasound in Cholecystitis
The aim of this study is: 1. To describe the natural course of acute cholecystitis, by performing repeated ultrasound examinations from day of admission to hospital until day of surgery or discharge. 2.
- Trial name
- NCT03470220
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Cholelithiasis, Cholecystitis
Efficacy of Proficiency-based Versus Free Laparoscopic Training in Cholecystectomy on a Virtual Reality Simulator
Virtual reality devices are widely accepted tools to familiarize surgical novices with the principles of laparoscopy. Free Virtual reality training will be tested against basic training and efficacy assessed in a randomized…
- Conditions
- Cholelithiasis, Cholecystitis, Cholecystolithiasis
- Trial name
- NCT01615549
- Testing
- Laparsocopic cholecystectomy
- Where
- 2 sites in Switzerland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hemodynamics Instability, Post Operative Pain
Evaluating Perioperative Outcomes: Dexmedetomidine vs Lignocaine in Laparoscopic Chlolecystectomy
Nowadays laparoscopic surgery is the first choice for many surgeries. Such surgeries have revolutionized the surgical practice and has markedly reduced the incidence of intraoperative and postoperative complications.
- Conditions
- Hemodynamics Instability, Post Operative Pain, Gastrointestinal Dysfunction, Cholecystitis
- Trial name
- NCT06740903
- Testing
- inj. dexmedetomidine infusion @ 0.2-0.4 μg/kg/h, inj. lignocaine infusion @1-2 mg/kg/h
- Where
- Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Ascites, Blunt Abdominal Trauma
Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community
The role of teleradiology has far reaching implications for the health of remote and underserved populations. The ability to coordinate radiographic evaluation and diagnosis from a distance has the potential to raise the standard…
- Conditions
- Ascites, Blunt Abdominal Trauma, Cholelithiasis, Cholecystitis
- Trial name
- NCT00591968
- Testing
- SonoSite Titan portable ultrasound coupled with email telediagnosis
- Where
- Dominican Republic
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Acute Cholecystitis, Colorectal Cancer
Safety and Feasibility of ActivSightTM in Human
ActivSightTM combines an innovative form factor and proprietary software to deliver precise, objective, real-time visualization of blood flow and tissue perfusion intraoperatively for laparoscope-based surgery.
- Conditions
- Acute Cholecystitis, Colorectal Cancer, Diverticulitis, Colonic, Obesity, Morbid
- Trial name
- NCT04633512
- Testing
- ActivSight
- Where
- 3 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Activ Surgical
Cholecystitis; Acute, With Cholelithiasis
Is an Antibiotic Prescription Required After Laparoscopic Cholecystectomy
The need for antibiotics to reduce surgical site infection after cholecystectomy for acute calculous cholecystitis is still controversial.
- Trial name
- NCT04290104
- Testing
- 1gr oral ampicillin/sulbactam group
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Gall Bladder Pain, Hepatobiliary Iminodiacetic Acid
Ejection Fraction of Normal Gall Bladder on Ultrasonography in Patients With Biliary Colic: Is it a Predictor of Cholecystectomy?
In this study investigators aim to evaluate gallbladder ejection fraction as a predictor for cholecystectomy.
- Conditions
- Gall Bladder Pain, Hepatobiliary Iminodiacetic Acid, Acalculous Cholecystitis
- Trial name
- NCT05587933
- Testing
- cholecystectomy, Antispasmodic
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acute Cholecystitis
Cholecystectomy Could be Performed in Older Adults With Acute Cholecystitis
The goal of this retrospective cohort observational study is to learn about the long-term and short-term effects of cholecystectomy in people aged 80 or over the age of 80, who have mild to moderate acute cholecystitis.
- Trial name
- NCT06601855
- Testing
- Cholecystectomy
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital