Clinical trials: Cholecystolithiasis
Choledocholithiasis With Acute Cholangitis
Effectiveness and Safety of Single-session Endoscopic Stone Extraction
This is a prospective study, including approximately 64 patients with acute cholangitis accompanied with choledocholithiasis at Beijing Friendship Hospital.
- Trial name
- NCT06349954
- Testing
- single-session ERCP, two-session ERCP
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Beijing Friendship Hospital
Cholelithiasis
Antibiotic Prophylaxis in Laparoscopic Cholecystectomy
The trial aims to assess the value of two-regimen antibiotic prophylaxis versus placebo in elective laparoscopic cholecystectomy.
- Trial name
- NCT01888822
- Testing
- Ciprofloxacin, Ampicillin-sulbactam
- Where
- Italy
- Volunteers
- 138 people
- Sponsor
- University of Roma La Sapienza
Gallstone
Effectiveness of Guided Imagery Meditation in Patients With Laparoscopic Gallstone Surgery
Guided image meditation has been shown to alter the functional circuits of the brain to alleviate pain by mediating breathing and thoughts.
- Trial name
- NCT04390828
- Testing
- Guided Imagery Meditation
- Where
- 2 sites in Taiwan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University Hospital
Clostridium Butyricum Miyairi, Gallstones
Probiotics for Gallstones in Post-bariatric Surgery Patients：A Prospective Randomized Trial
Morbid obesity has become a major global health problem, and the use of bariatric surgery is increasing. One common complication seen following bariatric surgery is the formation of gallstones.
- Conditions
- Clostridium Butyricum Miyairi, Gallstones, Gastrointestinal Quality of Life Index
- Trial name
- NCT03247101
- Testing
- Miyarisan-BM (Clostridium Butyricum Miyairi), Urso group, Biotase group
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Min-Sheng General Hospital
Postoperative Pain, Acute Cholecystitis
USG-Guided TAPA vs RIFB Block for Postoperative Analgesia in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy (LC) can cause moderate-to-severe postoperative pain from visceral, referred shoulder, and incisional sources. Multimodal analgesia is recommended, but opioids carry significant side effects.
- Conditions
- Postoperative Pain, Acute Cholecystitis, Cholelithiasis, Postoperative Nausea and Vomiting
- Trial name
- NCT07552701
- Testing
- M-TAPA Group, RIFPB Group
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Hitit University
Common Bile Duct Gall Stones, Common Bile Duct GallStones
Rate of Duodenal-biliary Reflux Increases in Patients With Recurrent Common Bile Duct Stones
ERCP is the primary choice for removal of common bile duct stone (CBDS) currently. However, 4-24% patients underwent recurrence after successful clearance of CBDS.
- Trial name
- NCT02329977
- Testing
- standard barium meal examination
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Air Force Military Medical University, China
Cholelithiasis
The Effect of Preoxygenation on Gastric Decompression in Laparoscopic Cholecystectomies
Aim: Gastric insufflation caused by mask ventilation during laparoscopic surgeries may affect the surgical field, lead to regurgitation of gastric contents, and consequently cause aspiration pneumonia.
- Trial name
- NCT07274488
- Testing
- Preoxygenation, Mask Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Ankara City Hospital Bilkent
Cholelithiasis
Effectiveness of Ursodeoxycholic Acid Use in the Prevention of Gallstone Formation After Sleeve Gastrectomy
This is a randomized double-blind placebo-controlled trial with a total of 100 patients who are free of gallstones at baseline. The study involves taking an oral drug (Ursodeoxycholic Acid 250mg) or a placebo twice daily for a…
- Trial name
- NCT02721862
- Testing
- Ursodeoxycholic Acid, Gallbladder Ultrasound
- Where
- 2 sites in Lebanon
- Volunteers
- 100 people
- Sponsor
- American University of Beirut Medical Center
Symptomatic Gallstones, Gallbladder Polyp
AI-Assisted Cholecystectomy Study
The objective of this prospective clinical pilot study is to evaluate the clinical feasibility, safety, and workflow integration of the voice-based AI-assisted robotic system for performing selected auxiliary tasks during robotic…
- Trial name
- NCT07705828
- Testing
- AI-Assisted Cornerstone Robotics Sentire Surgical System
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- Chinese University of Hong Kong
Cholecystolithiasis
UDCA for Symptomatic Gallstone Disease
We conduct a randomized, double-blind, placebo-controlled trial on effects of UDCA on biliary pain and complications in highly symptomatic gallstone patients scheduled for cholecystectomy.
- Trial name
- NCT00161083
- Testing
- ursodeoxycholic acid
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- UMC Utrecht
Gallstones
Effect of Virtual Reality Training by Novices on Laparoscopic Cholecystectomy in a Porcine Model
This study proposes evaluation of an educational tool, a laparoscopic virtual reality simulator. The purpose of this study is to determine whether training on the LapSim Simulator transfers to improved laparoscopic…
- Trial name
- NCT00460980
- Testing
- Virtual reality laparoscopic simulator training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Biliary Stricture, Cholangiocarcinoma
ENHANCED RECOVERY AFTER BILIARY TRACT SURGERY
The aim of the study is to improve the immediate results after reconstructive and restorative operations on the biliary tract by substantiating the management of the perioperative period on the principles of "enhanced recovery…
- Conditions
- Biliary Stricture, Cholangiocarcinoma, Cholangitis; Choledocholithiasis
- Trial name
- NCT04633382
- Testing
- Enhanced recovery after biliary tract surgery
- Volunteers
- 50 people
- Sponsor
- Vitebsk State Medical University
Cholelithiasis, Postoperative Pain
Pain Diary Use After Laparoscopic Cholecystectomy
This randomized controlled study aims to evaluate the effectiveness of using a pain diary in the assessment of early postoperative pain in patients undergoing laparoscopic cholecystectomy.
- Trial name
- PDP-LC (NCT07308730)
- Testing
- Postoperative Pain Management Protocol for Laparoscopic Cholecystectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Muğla Sıtkı Koçman University
Cholangiopancreatography, Endoscopic Retrograde
Long-duration EPBD vs EST for Removal of Biliary Stones
Although EPBD has a lower risk of post-ERCP bleeding and long-term complications than EST and is easier to perform in altered/difficult anatomy, EPBD is reserved for patients with bleeding diathesis by current consensus because…
- Trial name
- NCT03683485
- Testing
- long duration EPBD, EST
- Where
- 4 sites in South Korea
- Volunteers
- 358 people
- Sponsor
- Dankook University
Uterine Fibroids (Leiomyoma), Ovarian Tumors
TEAS Combined With Triple Antiemetic Drugs to Prevent PONV in High-Risk Patients
The goal of this clinical trial is to evaluate the effects of transcutaneous electrical acupoint stimulation (TEAS) combined with triple antiemetics for postoperative nausea and vomiting (PONV) in high-risk patients.
- Conditions
- Uterine Fibroids (Leiomyoma), Ovarian Tumors, Gallstones
- Trial name
- NCT07480785
- Testing
- transcutaneous electrical acupoint stimulation, triple antiemetic drugs
- Where
- China
- Volunteers
- 780 people
- Sponsor
- Zhejiang University
Acute Pancreatitis, Acute Pancreatic Necrosis
coMpliAnce With evideNce-based cliniCal Guidelines in the managemenT of Acute biliaRy pancreAtitis
Acute pancreatitis (AP) is an inflammatory disease of the pancreas, most commonly caused by gallstones, or excessive use of alcohol. It represents a management challenge and a significant healthcare burden.
- Conditions
- Acute Pancreatitis, Acute Pancreatic Necrosis, Acute Pancreatitis Due to Gallstones, Acute Pancreatic Fluid Collection
- Trial name
- MANCTRA-1 (NCT04747990)
- Testing
- Early Definitive Treatment
- Where
- 3 sites in Italy, Spain
- Volunteers
- 600 people
- Sponsor
- University of Cagliari
Cholecystolithiasis
A Survey of Public Attitudes Towards Gallbladder-preserving Lithotomy and Its Influencing Factors
This study aims to understand public/patient attitudes toward gallbladder preservation surgery by means of questionnaires, and hopes to achieve the following objectives: 1.
- Trial name
- NCT07854379
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Changzhou No.2 People's Hospital
Choledocholithiasis, Common Bile Duct Stones
Hyoscine Butylbromide During Transcystic Papillary Balloon Dilation for Choledocholithiasis
The purpose of the PAPRELAX study is to evaluate the intraoperative effect of intravenous hyoscine butylbromide during laparoscopic transcystic balloon dilation of the papilla of Vater in adult patients undergoing surgical…
- Trial name
- PAPRELAX (NCT07814976)
- Testing
- Hyoscine Butylbromide
- Where
- Latvia
- Volunteers
- 50 people
- Sponsor
- Riga East Clinical University Hospital
Common Bile Duct Calculi
Symbolic Regression Model To Predict Choledocholithiasis
Choledocholithiasis refers to the presence of gallstones within the common bile duct. It is proposed to look for markers that help in the diagnosis and in differentiating between retained and migrated gallstones.
- Trial name
- (SymChole) (NCT04410848)
- Testing
- To determine the diagnostic of Choledocholithiasis with symbolic regression model
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Cholecystitis/Cholelithiasis, Cholecystitis; Gallstone
Potential Pulmonary Benefit of Low Pressure Laparoscopic Cholecystectomy in Selected Patients
Standard Pressure Laparoscopic Cholecystectomy，as the standard for cholecystectomy, can lead to about 15% of pulmonary atelectasis.
- Conditions
- Cholecystitis/Cholelithiasis, Cholecystitis; Gallstone, Polyp Gallbladder
- Trial name
- POPLOP (NCT04670952)
- Testing
- Low Pressure Laparoscopic Cholecystectomy, Standard Pressure Laparoscopic Cholecystectomy
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Peking Union Medical College Hospital