Clinical trials: Choledocholithiasis
Cholecystitis, Cholecystitis; Gallstone
Dutch Cholecystitis Snapshot Study
Background: Cholecystitis is treated by in various types of hospitals by different specialists, and treatment strategy is influenced by logistical and medical reasons and personal preference.
- Conditions
- Cholecystitis, Cholecystitis; Gallstone, Cholecystitis; Choledocholithiasis
- Trial name
- Dutch CHESS (NCT06349863)
- Where
- Netherlands
- Volunteers
- 3,000 people
- Sponsor
- St. Antonius Hospital
Choledocholithiasis With Acute Cholangitis
Efficacy and Safety of Single-session Endoscopic Stone Extraction
This is a retrospective study, including approximately 600 patients with acute cholangitis accompanied with choledocholithiasis, who treated with single-session or two-session endoscopic stone extraction at Beijing friendship…
- Trial name
- NCT06327126
- Testing
- two-session ERCP, single-session ERCP
- Where
- China
- Volunteers
- 563 people
- Sponsor
- Beijing Friendship Hospital
Choledocholithiasis With Cholecystitis, Biliary Stones
Single-stage ERCP and Laparoscopic Cholecystectomy for Cholecystocholedocholithiasis: Which to Start With?
Chronic calculous cholecystitis is associated with common bile duct (CBD) stones in approximately 12% of patients. These patients need both cholecystectomy and CBD clearance of stones.
- Trial name
- NCT06340594
- Testing
- Laproscopic cholecystectomy (LC), Endoscopic Retrograde Cholangiopancreatography (ERCP)
- Where
- Egypt
- Volunteers
- 115 people
- Sponsor
- Assiut University
Choledocholithiasis, Asymptomatic Condition
The Treatment Effect for Asymptomatic Common Bile Duct Stone
This study is prospective, multicenter study for identify the characteristics of asymptomatic common bile duct stones and effectiveness of treatment.
- Conditions
- Choledocholithiasis, Asymptomatic Condition, Quality of Life
- Trial name
- NCT06215040
- Testing
- Endoscopic retrograde cholangiopancratography
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Hospital
Choledocholithiasis
Comparison of LCBDE vs ERCP + LC for Choledocholithiasis
Protection of Oddi's sphincter remains a huge argument especially in the long term complications like common bile duct stone recurrence or cholangitis after ERCP, which determined to destroy the sphincter of Oddi.
- Trial name
- NCT02515474
- Testing
- Laparoscopy, Endoscopy
- Where
- 12 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Choledocholithiasis, Bile Duct Diseases
Cholangiography Using Carbon Dioxide Versus Iodinated Contrast in ERCP
Carbon dioxide (CO2) gas is widely used for luminal insufflation during endoscopic retrograde cholangiopancreatography (ERCP) of the biliary tract.
- Conditions
- Choledocholithiasis, Bile Duct Diseases, Bile Duct Carcinoma
- Trial name
- NCT02611453
- Testing
- "Air" contrast cholangiography using carbon dioxide gas
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Virginia
Jaundice, Obstructive, Jaundice; Malignant
Microbiological Assessment of Bile in Patients Undergone to Endoscopic Retrograde Cholangiography (ERCP): the "Microbile Registry"
The study is a prospective evaluation of the microbial assessment in patients undergoing to ERC with naive papilla; the population includes all the indication to biliary drainage.
- Conditions
- Jaundice, Obstructive, Jaundice; Malignant, Choledocholithiasis, Biliary Stricture
- Trial name
- Microbile (NCT06115564)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Unità Sanitaria Locale della Romagna
Choledocholithiasis
Role of Prophylactic Biliary Stent in Reducing the Recurrence of Choledocholithiasis
We planned this multicenter randomized controlled trial to study the role of a prophylactic biliary stent in recurrence of stones and biliary complications in patients awaiting cholecystectomy after biliary stone clearance
- Trial name
- STONE (NCT06060002)
- Testing
- Group A - Stent exchange if cholecystectomy dated beyond 3 months, Group B - Diagnostic EUS/MRCP/USG abdomen and LFT at 3 months
- Volunteers
- 480 people
- Sponsor
- Asian Institute of Gastroenterology, India
Intrahepatic Bile Duct Stone, Choledocholithiasis
Recurrent Extrahepatic Bile Duct Stones as a Late Complication of ERCP in Patients With Coexisting Intra- and Extrahepatic Bile Duct Stones
The management of coexisting intrahepatic bile duct (IBD) and extrahepatic bile duct (EBD) stones is complicated and requires a multidisciplinary approach.
- Trial name
- NCT06041113
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Air Force Military Medical University, China
Choledocholithiasis
RCT on Robotic vs. Endo-laparoscopic Approach for Difficult Choledocholithiasis
Gallstone disease is a very common disease identity in the world. Migration of stones from gallbladder to common bile duct (CBD), causing CBD stones (choledocholithiasis), occurs in up to 22% of cases.
- Trial name
- NCT05611840
- Testing
- Robotic surgery, Endo-laparoscopic surgery
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- Chinese University of Hong Kong
Common Bile Duct Calculi, Acute; Cholecystitis, Choledocholithiasis
Modified Laparoscopic Transcystic Biliary Drainage in the Management of Cholecystocholedocholithiasis
The modified laparoscopic transcystic biliary drainage which we developed in the treatment of cholecystocholedocholithiasis has some advantages over conventional techniques.
- Conditions
- Common Bile Duct Calculi, Acute; Cholecystitis, Choledocholithiasis, Acute Cholecystitis With Obstruction, Acute Cholangitis
- Trial name
- NCT06011941
- Testing
- Modified laparoscopic transcystic biliary drainage
- Where
- China
- Volunteers
- 310 people
- Sponsor
- Peking University Third Hospital
Choledocholithiasis
EPLBD With Limited EST vs. EPLBD for Choledocholithiasis
Endoscopic papillary balloon dilation (EPBD) for choledocholithiasis is known to be comparable to endoscopic sphincterotomy (EST) especially in cases of small stones.
- Trial name
- NCT05056506
- Testing
- EPLBD, ELPBD+ESD
- Where
- 2 sites in China
- Volunteers
- 168 people
- Sponsor
- Jianfeng Yang
Cholangiopancreatography, Endoscopic Retrograde, Choledocholithiasis
Explore the Effects and Mechanisms of ERCP and EST on Biliary Microecology
The objective of this observational study is to explore the structure of biliary flora in normal people, explore the dynamic impact of ERCP and EST on biliary microecology, study the marker flora, metabolites and functional genes…
- Conditions
- Cholangiopancreatography, Endoscopic Retrograde, Choledocholithiasis, Gallstones
- Trial name
- NCT05592795
- Testing
- Whether ERCP or EST is carried out
- Where
- 3 sites in China
- Volunteers
- 75 people
- Sponsor
- Qi-Yong Li
Choledocholithiasis, Common Bile Duct Calculi
SpyGlass Versus ESWL for Large Common Bile Duct Stones
Overall stone clearance with endoscopic retrograde cholangiopancreatography (ERCP) for choledocholithiasis is a big problem, especially for stones with a diameter greater than 3cm.
- Trial name
- NCT05186350
- Testing
- ERCP+ SpyGlass, ESWL+ ERCP
- Where
- China
- Volunteers
- 65 people
- Sponsor
- First People's Hospital of Hangzhou
Cholecystolithiasis, Choledocholithiasis
Feasibility and Safety of Bile Duct Clearance by Transcystic Sphincter of Oddi Balloon Dilatation
To investigate feasibility and safety of intraoperative bile duct clearance by sphincter of Oddi balloon dilatation via cystic duct at cholecystectomy. Primary endpoint: rate of successful bile duct stone clearance (feasibility).
- Conditions
- Cholecystolithiasis, Choledocholithiasis, Surgery
- Trial name
- TCPBD (NCT04737642)
- Testing
- Papillary ballon dilatation
- Where
- Switzerland
- Volunteers
- 57 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Drainage, Laparoscopic Cholecystectomy
The Efficacy and Safety of Using Prophylactic Abdominal Drainage After Cholecystectomy
Investigators want to assess the safety and efficacy of using abdominal drainage with not using any drainage, by estimating different outcomes after laparoscopic cholecystectomy for different reasons.
- Conditions
- Drainage, Laparoscopic Cholecystectomy, Acute Cholecystitis
- Trial name
- NCT05267860
- Testing
- Prophylactic Drain
- Where
- Syria
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Choledocholithiasis
Endoscopic Sphincterotomy With Balloon Dilatation Versus Sphincterotomy Alone For Common Bile Duct Stones Removal
Gallstone is a worldwide clinical problem which affecting most of the populations with incidence of 15 to 20% in west and 10% in Asians. About 5 to 15% of patient with gallstone will go on to develop bile duct calculi.
- Trial name
- NCT05638789
- Testing
- endoscopic sphincterotomy (EST) versus EST plus endoscopic papillary large balloon dilatation (EPLBD)
- Where
- Malaysia
- Volunteers
- 66 people
- Sponsor
- Hospital Universiti Sains Malaysia
Bile Duct Stricture, Choledocholithiasis
Direct Peroral Cholangioscopy by Using an Ultra-slim Upper Endoscope
This study was aimed to to evaluate the efficacy of the new multibending ultra-slim endoscope compared with a conventional ultra-slim endoscope for free-hand insertion of an endoscope into the bile duct for direct POC.
- Trial name
- NCT02276157
- Testing
- Direct peroral cholangioscopy
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Soonchunhyang University Hospital
Choledocholithiasis
Modified Laparoendoscopic Rendezvous for Secondary Choledocholithiasis: a Nonrandomized Controlled Clinical Study
This study intends to explore the success rate and clinical efficacy of modified LERV in the treatment of patients with non-dilated common bile duct (internal diameter ≤10mm) through a non-randomized controlled clinical trial…
- Trial name
- NCT05542784
- Testing
- Modified LERV
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shenzhen Second People's Hospital
Biliary Disease, Pancreatitis
Los Angeles Prospective GI Biliary and EUS Series
Endoscopic retrograde cholangiopancreatography and endoscopic ultrasound are increasingly being used to manage complex disease of the bile duct, pancreas and cancer.
- Conditions
- Biliary Disease, Pancreatitis, Gastrointestinal Neoplasms
- Trial name
- NCT02196935
- Testing
- clinical course
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- University of Southern California