Clinical trials: Cholesterol
Dyslipidemias
Study to Evaluate the Safety of the Fixed-dose Combination Rosuvastatin/Ezetimibe for Patients With Dyslipidaemia
Retrospective, analytical, longitudinal, multicenter study to evaluate the safety of the fixed-dose combination of rosuvastatin / ezetimibe as treatment for patients with dyslipidemia in routine medical practice.
- Trial name
- TREZETE (NCT04862962)
- Testing
- Rosuvastatin 10 or 20mg /Ezetimibe 10 mg Fixed Dose
- Where
- Mexico
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Mild Hypercholesterolemic Subjects
Effect of the Consumption of a Fermented Dairy Product Enriched With Plant Sterols
The purpose of this study is to investigate the cholesterol lowering effect of a drinkable low fat fermented milk enriched with plant sterols after 3 weeks of daily consumption in midly hypercholesterolemic people.
- Trial name
- NCT01521156
- Testing
- 1- low-fat dairy fermented product (drinkable) enriched with plant sterols-esters (1,6g /day equivalent as free sterols)., 2- low-fat dairy fermented product (drinkable) enriched with experimental plant sterols-esters (1,6g /day equivalent as free sterols).
- Where
- Germany
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Cholesterol, Lipid Profile
Effect of Curd Cheese on Metabolic Health in Adults
This randomized controlled trial aims to evaluate the effects of a diet supplemented with curd cheese on anthropometric measurements, glycemia, and lipid profile in overweight adults.
- Conditions
- Cholesterol, Lipid Profile, Diabete Mellitus
- Trial name
- NCT07676838
- Testing
- Curd Cheese Supplemented Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Süleyman Kılıç
LDL Cholesterol
Effect of Viscous Soluble Fibers on Serum Cholesterol Levels
Research over the past several decades have linked the intake of dietary fiber with lower blood cholesterol levels. The distinction between soluble and insoluble fiber fractions emerged shortly after and there is now a general…
- Trial name
- CHOL-META (NCT02068248)
- Testing
- Soluble Fibre
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Menopause, Postmenopause
Midlife Cholesterol Study
The postmenopausal state is associated with an increase risk for heart disease. Much of this increase in risk may be due to the loss of estrogen (the main female hormone) and the effect of this loss on lipids (blood fats).
- Conditions
- Menopause, Postmenopause, Premenopause, Cardiovascular Disease
- Trial name
- NCT00361075
- Testing
- transdermal estradiol patch (Vivelle), oral estrogen (Estrace), progesterone (Prometrium)
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Acne Cystic, Diet, Healthy
Effect of Different Diets on Isotretinoin Users to Serum Lipid Levels
This research was planned to prevent secondary hyperlipidemia, which may occur due to isotretinoin used in the treatment of severe acne, with diet. There will be three different groups and followed for 12 weeks.
- Trial name
- NCT06250673
- Testing
- Diet experiment
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Igdir University
To Determine Bioequivalence Under Fed Conditions
A Comparative Bioavailability Study of Lisinopril Tablets, 40 mg - Effect of Food Study
The purpose of this study is to compare the bioavailability of Par Lisinopril 40 mg Tablets and IPR Pharmaceuticals, Inc. Zestril (R).
- Trial name
- NCT01380431
- Testing
- Lisinopril
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Par Pharmaceutical, Inc.
Cholesterol, Cholesterol (total and HDL)
Natural Heart Health Supplement Trial
We are running a 3-month trial of an experimental natural heart health supplement. Participants will take a daily dose of an experimental natural heart health supplement in powdered format, chocolate flavor.
- Trial name
- NCT06671769
- Testing
- Heart Health Supplement
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Efforia, Inc
CYP3A4 Induction
Cholesterol Metabolites as Markers for CYP3A Induction
The objectives of this study are: To investigate if the endogenous cholesterol metabolite, 4beta-OHcholesterol could be used as a marker for induction of cytochrome P450 (CYP) 3A4.
- Trial name
- NCT01340456
- Testing
- Rifampicin treatment
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Hypercholesterolemia
Kefir Cholesterol Lowering Pilot Study
High cholesterol (a type of fat in humans blood) may be one factor that can lead to heart disease. If people have higher cholesterol, it is possible that kefir (a food similar to yogurt) may help to control blood cholesterol…
- Trial name
- NCT04247139
- Testing
- Kefir
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Cardiovascular Disease
Impact of Buttermilk on Cholesterol Concentration and Homeostasis
The role of low-density lipoprotein cholesterol (LDL-C) in the pathogenesis of cardiovascular disease (CVD) and the clinical benefit of lowering LDL-C in high-risk patients have both been well established.
- Trial name
- BMILK (NCT01248026)
- Testing
- Buttermilk
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Laval University
Dyslipidemias
Effect of Niacin on Transport of HDL and Relationship to Atherogenic Lipoproteins and Lipolysis
This study looks at whether niacin improves reverse cholesterol transport (RCT) in healthy volunteers. 3H-Cholesterol will be used to measure RCT by analyzing changes in the tracer activity in total plasma, lipoproteins, red…
- Trial name
- ENTHRALL (NCT01250990)
- Testing
- Niacin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Healthy Diet, Cholesterol
Health-related Benefits of Introducing Table Olives Into the Diet of Young Adults: Olives For Health
The purpose of this study is to assess whether introducing table olives into the diet results in health-related benefits for young adults.
- Conditions
- Healthy Diet, Cholesterol, Healthy Lifestyle, Healthy Nutrition
- Trial name
- NCT05218980
- Testing
- Olives
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Yale University
Cardiovascular Risk Factor
The Investigation of Effect on Blood Lipid Parameters With Walnut Addition of Diet
Introduction There is a strong relationship between eating habits and diseases of the cardiovascular system. It is known that walnut consumption has positive effects on cardiovascular system diseases.
- Trial name
- NCT04583696
- Testing
- The Investigation of effect on Blood Lipid parameters with walnut addition of Diet
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ege University
Hypercholesterolemia, Osteoporosis
Effect of β-cryptoxanthin (β-Cx), Plant Sterols and Galactooligosaccharides on Systemic and Gastrointestinal Markers
Regular consumption of a beverage containing β-cryptoxanthin (β-Cx) and plant sterols (PS) has been shown to exert a synergic effect in reducing some markers of cardiovascular risk and bone-remodeling (formation and resorption).
- Conditions
- Hypercholesterolemia, Osteoporosis, Postmenopausal Disorder
- Trial name
- NCT03469518
- Testing
- β-Cx plus PS plus GOS, β-Cx plus PS
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Puerta de Hierro University Hospital
Obesity
Metabolic Effects of a Caloric Restriction High/Low Glycemic Index Diet Plus Metformin in Overweight/Obese Subjects
The prevalence of obesity and Type 2 diabetes has increased dramatically worldwide. Research on Glycemic Index (GI) diets has been largely developed, however the combination with metformin in humans was not investigated yet.
- Trial name
- NCT01460797
- Testing
- Glycemic Index Diets and Metformin hydrochloride
- Where
- Brazil
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Caio Eduardo Gonçalves Reis
Immunosuppression, Hyperlipidemias
Cholesterol and Fatty Acid Synthesis in Islet and Liver Transplant Patients and Effect of Dietary Intervention
The purpose is to investigate possible mechanisms of increased blood lipid levels following transplantation, and also to see if a comprehensive dietary intervention is effective in reducing blood lipid levels in post-transplant…
- Conditions
- Immunosuppression, Hyperlipidemias, Diabetes Mellitus, Type 1
- Trial name
- NCT00947635
- Testing
- Dietary intervention - supplements
- Where
- Canada
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Cardiovascular Disease, Cigarette Smoking
Cardiovascular Disease Biomarkers in Smokers and Moist Snuff Consumers
This cross-sectional study was primarily a cardiovascular disease (CVD) study designed a) to compare selected CVD biomarker data between subjects who were long-term consumers of cigarettes or moist snuff and non-consumers of…
- Trial name
- NCT01692353
- Testing
- Subject's usual brand (UB) tobacco product
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- R.J. Reynolds Tobacco Company
Cholesterol
Dietary Cholesterol and Adipose Tissue Inflammation
Hypothesis: increasing dietary cholesterol in humans will increase visceral, but not subcutaneous adipocyte size, free cholesterol content, and inflammatory gene expression.
- Trial name
- NCT03729141
- Testing
- Added Cholesterol, No Added Cholesterol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Atherosclerosis, Postmenopause
EPAT: Estrogen in the Prevention of Atherosclerosis Trial
The purpose of this study is to determine the effects of estrogen replacement therapy (ERT) on the progression of early atherosclerosis in healthy postmenopausal women without preexisting cardiovascular disease (CVD).
- Trial name
- NCT00115024
- Testing
- Micronized 17B-estradiol
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)