Clinical trials: Cholesterol (Total and HDL)
Cardiovascular Disease
Clinical Study to Assess High-DHA Fish Oil on Biomarkers of Cardiovascular Disease Risk in Adults on Statin Therapy
The objective of this study is to determine the acute and chronic [4-week] effects of a high-DHA fish oil supplement on fasting and post-prandial (post-meal) biomarkers of cardiovascular disease risk, in adults on Statin therapy.
- Trial name
- NCT01690312
- Testing
- Fish Oil
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
Disbiosis, Obesity
Limosilactobacillus Fermentum CRL 1446 - CONICET CASASCO
This research study aims to determine if a probiotic called Limosilactobacillus fermentum CRL 1446 can improve the health of people at risk for cardiovascular disease.
- Conditions
- Disbiosis, Obesity, Overweight (BMI > 25), Hypertension (Without Type 2 Diabetes Mellitus)
- Trial name
- NCT07530575
- Testing
- Limosilactobacillus fermentum 1446 CRL CONICET 2.20E+9 CFU
- Where
- 2 sites in Argentina
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- PINER Pastor Manfredi Winery
Weight Change, BMI
Childhood Obesity Prevention Project in Gran Canaria
Given the alarming rates of obesity and overweight in our child population, the investigators have developed an intervention strategy, based on a multidisciplinary, school-centered approach, which addresses nutritional education…
- Conditions
- Weight Change, BMI, Activity Level, Cholesterol (total and HDL)
- Trial name
- POI (NCT06607159)
- Testing
- Implementation of healthy habits teaching protocol
- Where
- Spain
- Volunteers
- 557 people, healthy volunteers welcome
- Sponsor
- Complejo Hospitalario Universitario Insular Materno Infantil
HDL
Oral Nutritional Supplement Effect on HDL Function
Evaluate the effects of a proprietary supplement on total HDL, HDL functionality, HDL particle size and HDL particle number (HDL-P)
- Trial name
- NCT04529174
- Testing
- CardioLux™HDL
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Type 2 Diabetes
Effects of Cranberry Extractive on the Lipid Profiles in Subjects With Type 2 Diabetes
Cranberry, containing flavonoids, is effective on improvement of lipid profiles in non-diabetic subjects. The Hypothesis of is to assess the effect of cranberry on lipid profiles in type 2 diabetic patients using oral…
- Trial name
- NCT00695526
- Testing
- cranberry
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taichung Veterans General Hospital
Cholesterol (Total and HDL), Exercise
Step-Aerobics Versus Core Exercise for Non-HDL Cholesterol Reduction in Sedentary/Obesity Women
This study investigated the effects of a step-aerobics program versus a core exercise program on serum non-HDL-C levels and other cardiometabolic parameters in sedentary women with overweight/obesity.
- Trial name
- NCT07703202
- Testing
- Intervention 1: Step-Aerobics Program, Intervention 2: Core Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Overweight, Obesity
Meta-analyses of the Effect of Liquid Meal Replacements on Cardiometabolic Risk
Obesity is a major risk factor for cardiovascular disease and diabetes. Weight loss is an important therapeutic goal for overweight and obese patients to reduce their risk of developing cardiovascular disease and diabetes.
- Conditions
- Overweight, Obesity, Type 2 Diabetes
- Trial name
- NCT02779790
- Testing
- Liquid Meal Replacements
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Hypercholesterolaemia
Evaluation of Patients Treated With HMG-CoA Reductase Inhibitors to Reach Cholesterol Target Values
This study is non-interventional study of patients who are treated with any HMGCoA reductase inhibitors (rosuvastatin, simvastatin,atorvastatin and fluvastatin) available in Bosnia and Herzegovina for at least 6 months.
- Trial name
- NCT01483950
- Where
- 14 sites in Bosnia and Herzegovina
- Volunteers
- 800 people
- Sponsor
- AstraZeneca
HIV Infections
To Determine if Chromium Nicotinate Supplementation Will Improve Insulin Resistance in HIV Patients With Metabolic Abnormalities
In HIV patients, fasting insulin levels decrease with chromium supplementation. This study is to determine if chromium nicotinate supplementation at 400ug/day for 16 weeks will improve insulin resistance in HIV patients with…
- Trial name
- NCT00152893
- Testing
- chromium nicotinate
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Johane Allard
Hypercholesterolemia
Safety & Efficacy of a Combination Niacin ER/Simvastatin in Patients With Dyslipidemia: A Dose-Ranging Study - SEACOAST
The purpose of this study is to compare the effectiveness and safety of different doses of Niacin ER/Simvastatin (NS), in subjects with elevated fat levels in their blood (dyslipidemia).
- Trial name
- NCT00082251
- Testing
- Niacin extended release and simvastatin tablets
- Sponsor
- Kos Pharmaceuticals
Stable Angina, Unstable Angina
Differential Effects of Lipids on Cardiovascular Diseases: A CALIBER Study
The role of lipids as risk factors for cardiovascular events is well-documented, although events studied have largely been broad classes without specific detail. This study will examine a more refined set of endpoints.
- Conditions
- Stable Angina, Unstable Angina, Non ST Elevation Myocardial Infarction, ST Elevation Myocardial Infarction
- Trial name
- NCT01687686
- Where
- United Kingdom
- Volunteers
- 175,872 people
- Sponsor
- University College, London
Dyslipidemias, Hypercholesterolemia
Dachundou No Sugar Added Soymilk for Lipid Modulation
Cardiovascular disease is one of the leading causes of death worldwide, and high cholesterol is a major risk factor. Diet is known to play an important role in managing blood lipids.
- Conditions
- Dyslipidemias, Hypercholesterolemia, Cardiovascular Diseases
- Trial name
- DNS Soymilk (NCT07175766)
- Testing
- Dachundou No Sugar Added Soymilk
- Where
- Taiwan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Cholesterol, Cholesterol (total and HDL)
Natural Heart Health Supplement Trial
We are running a 3-month trial of an experimental natural heart health supplement. Participants will take a daily dose of an experimental natural heart health supplement in powdered format, chocolate flavor.
- Trial name
- NCT06671769
- Testing
- Heart Health Supplement
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Efforia, Inc
Blood Pressure, Heart Rate and Rhythm Disorders
Acute Maternal and Fetal Effects of Exercise in Pregnancy
This will be an open randomized clinical trial involving pregnant women between 35 and 37 weeks randomized to two modalities of exercise: treadmill or stationary bike.
- Conditions
- Blood Pressure, Heart Rate and Rhythm Disorders, Hypoglycemia, Lactate
- Trial name
- EXPREG (NCT01383889)
- Testing
- Physical exercise
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Inflammatory Arthritis, Cardiovascular Risk Factor
Pharmacist CVD Intervention for Patients With Inflammatory Arthritis
Cardiovascular disease (CVD) (disease of the heart and blood vessels) is one of the leading causes of death and disability in Canada today. The majority of CVD cases are caused by factors that can be controlled.
- Conditions
- Inflammatory Arthritis, Cardiovascular Risk Factor, Rheumatoid Arthritis, Ankylosing Spondylitis
- Trial name
- RxIALTA (NCT03152396)
- Testing
- CV risk assessment and modification of global risk
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Epidemiology Coordinating and Research Centre, Canada
Dyslipidemias, Cardiovascular Risk Factor
Meta-analyses of Soy Protein and Its Food Sources for Cholesterol Reduction
Although soy protein has approved health claims in Canada and the US, and is recognized by major cardiovascular clinical practice guidelines for the reduction of cholesterol and risk of coronary heart disease (CHD), these claims…
- Conditions
- Dyslipidemias, Cardiovascular Risk Factor, Dysglycemia
- Trial name
- NCT04861545
- Testing
- Soy
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Cholesterol (Total and HDL), Exercise
Step-Aerobics Versus Core Exercise for Non-HDL Cholesterol Reduction in Sedentary Women
This study investigated the effects of a step-aerobics program versus a core exercise program on serum non-HDL-C levels and other cardiometabolic parameters in sedentary women with overweight/obesity.
- Trial name
- NCT07350213
- Testing
- Step-Aerobics Group, Core Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Cholesterol Lowering, LDL Level
Evaluation of the Functionality of an Extract Rich in Phytosterols and Phytostanols on Parameters Related to the Lipid Profile of Individuals With Hypercholesterolemia, Mainly in the Levels of Total Cholesterol, LDL Cholesterol and Oxidized LDL
The aim of this clinical trial is to evaluate the functionality of an extract rich in phytosterols and phytostanols on parameters related to the lipid profile of individuals with hypercholesterolemia, mainly on total cholesterol…
- Trial name
- Hypolypox (NCT06954649)
- Testing
- Plant based extract rich in phytosterols and phytostanols resveratrol and hydroxytyrosol.
- Where
- 2 sites in Spain
- Volunteers
- 45 people
- Sponsor
- Centro de Edafología y Biología Aplicada del Segura
Diabetic Kidney Disease, Diabetes Mellitus, Type 2
Possible Ameliorating Effect of N- Acetylcysteine (NAC) on Type-II Diabetes Induced Nephropathy
The study is focused on the possible improving effect of N-acetylcysteine on nephropathy of type-2 diabetic patients. Study design: Prospective clinical based study.
- Conditions
- Diabetic Kidney Disease, Diabetes Mellitus, Type 2, Diabetic Nephropathies
- Trial name
- (NAC) (NCT04531163)
- Testing
- N Acetylcysteine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Hyperlipidemias, Hypertension
The Effect of Farlong® NotoGinseng™ (Ginseng Plus®) on Cholesterol and Blood Pressure
In this randomized, placebo-controlled, double-blind parallel study in human participants with elevated LDL-C and elevated BP described here, the clinical benefits of Farlong NotoGinseng™ (Farlong Ginseng Plus® Panax Notoginseng…
- Trial name
- NCT04069715
- Testing
- Farlong NotoGinseng™ (Farlong Ginseng Plus® Panax Notoginseng extract)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- LongStar HealthPro, Inc. DBA Farlong Pharmaceutical