Clinical trials: Chorioretinopathy, Central Serous
Central Serous Chorioretinopathy
Eplerenone for Central Serous Chorioretinopathy
The goal of the study is to examine the short-term effects and safety of a systemic anti-aldosterone medication, eplerenone, in a small group of patients with central serous chorioretinopathy (CSCR).
- Trial name
- NCT01822561
- Testing
- Eplerenone 50mg
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Tufts Medical Center
Retinal Artery Occlusions, Polypoidal Choroidal Vasculopathy
OCT in Rare Chorioretinal Diseases
This study will evaluate the total blood flow in the retina and choroid (structures in the back of the eye) by Doppler optical coherence tomography (OCT) and OCT angiography. Angiography is mapping of the blood vessels.
- Conditions
- Retinal Artery Occlusions, Polypoidal Choroidal Vasculopathy, Retinal Arterial Macroaneurysm, Juxtafoveal Telangiecasia
- Trial name
- NCT02141308
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Oregon Health and Science University
Age-Related Macular Degeneration, Geographic Atrophy
Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO
To conduct a precision study to assess the microperimetry function of the Spectral OCT/SLO. The study will assess variability across measurements taken by three different operator-device configuration across clinical sites…
- Conditions
- Age-Related Macular Degeneration, Geographic Atrophy, Diabetic Retinopathy, Macular Edema
- Trial name
- NCT01692938
- Where
- 3 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Optos, PLC
Chronic Central Serous Chorioretinopathy
Treatment of Chronic Central Serous Chorioretinopathy With Open-Label Anecortave Acetate
Investigation to evaluate Anecortave Acetate in the treatment of chronic central serous chorioretinopathy
- Trial name
- CSC-AA (NCT00489840)
- Testing
- Anecortave Acetate Sterile suspension 15 mg, Anecortave Acetate
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Manhattan Eye, Ear & Throat Hospital
Choroidal Neovascularization, Mineralocorticoid Excess
Biomarkers and Choroidal Neovascularization
The aim of the study is to find biomarkers in the blood and aqueous humor of patients with type 1 choroidal neovascularization and correlate them with the response to anti-VEGF treatment.
- Trial name
- BioNéoRet (NCT04439708)
- Testing
- Blood and aqueous humor biomarker of treatment response
- Where
- 2 sites in France
- Volunteers
- 250 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Central Serous Chorioretinopathy
The Safe Effective Light Dose of Photodynamic Therapy for Chronic Central Serous Chorioretinopathy
To find the safe effective lowest light dose for photodynamic therapy (PDT). in the treatment of central serous chorioretinopathy.
- Trial name
- NCT01630863
- Testing
- Photodynamic therapy
- Where
- South Korea
- Volunteers
- 45 people
- Sponsor
- Yeungnam University College of Medicine
Age Related Macular Degeneration, Choroidal Neovascularization
Genetic Analysis of Chronic Central Serous Chorioretinopathy Masquerading as Neovascular AMD
The study will be designed as a case control evaluation to compare the genetic profiles of three groups of patients categorized according to diagnosis.
- Conditions
- Age Related Macular Degeneration, Choroidal Neovascularization, Central Serous Chorioretinopathy
- Trial name
- NCT01880788
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Sequenom, Inc.
Chronic Central Serous Chorioretinopathy
Photodynamic Therapy Using Verteporfin for Treatment of Chronic Central Serous Chorioretinopathy (CSC)
Central serous choroidal (CSC) retinopathy is a disease of the macula characterized by exudation of fluid under the retina localized to the posterior pole as well as loss of vision.
- Trial name
- NCT00211445
- Testing
- Photodynamic Therapy with Verteporfin, verteporfin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Manhattan Eye, Ear & Throat Hospital
Central Serous Chorioretinopathy (CSC)
Prospective Geometric Analysis of Ultra-Widefield OCTA Characteristics in Central Serous Chorioretinopathy Patients
By leveraging parameters including fractal dimension and topological index, we constructed a quantitative evaluation framework for ultra-widefield optical coherence tomography angiography (UWF-OCTA) images in patients with…
- Trial name
- NCT07347119
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Central Serous Chorioretinopathy
Panmacular Versus Minimal Micropulse Laser Therapy in Central Serous Chorioretinopathy
Central serous retinopathy is a disease of poorly understood etiology characterized by accumulation of subretinal fluid and leading to significant decrease in vision.
- Trial name
- NCT04410861
- Testing
- Micropulse laser photostimulation
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- Moorfields Eye Hospital Centre Abu Dhabi
Central Serous Chorioretinopathy
the Study of the Association Between the Gut Microbiota and Central Serous Chorioretinopathy
To investigate the potential association between gut microbiota and central serous chorioretinopathy (CSC), clinical observations have indicated that patients with CSC frequently present with chronic gastrointestinal symptoms.
- Trial name
- NCT06527326
- Testing
- Live Combined Bifidobacterium
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Central Serous Chorioretinopathy
Central Serous Chorioretinopathy Treated by Modified Photodynamic Therapy
The purpose of this study is to evaluate the effectiveness as well as the detrimental influence of half-dose and half-fluence modification of verteporfin photodynamic therapy (PDT) for the treatment of prolonged unresolved…
- Trial name
- NCT01019668
- Testing
- Verteporfin PDT, half-dose, verteporfin PDT, half-fluence
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Chorioretinopathy, Obstructive Sleep Apnea
Association Between CRSA and OSA
This goal of this study is to know the association between the central serous chorioretinopathy and the obstructive sleep apnea.
- Trial name
- CRSA (NCT04634786)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Poitiers University Hospital
Macular Edema, Radiation Retinopathy
Episcleral Dexamethasone for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole
This phase I trial will assess primarily the safety and secondarily anti-inflammatory effect of Episcleral Dexamethasone in patients suffering from macular edema and other disorders of the retina, choroid and vitreous.
- Conditions
- Macular Edema, Radiation Retinopathy, Branch Retinal Vein Occlusion, Epiretinal Membrane
- Trial name
- NCT04120311
- Testing
- Episcleral Dexamethasone
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Targeted Therapy Technologies, LLC
Central Serous Chorioretinopathy
Central Serous Chorioretinopathy: Etiology, Course and Prognosis
Pathogenesis of central serous chorioretinopathy is not entirely understood yet, therefore further investigations are needed. During this study patients with an acute episode of central serous chorioretinopathy are observed with…
- Trial name
- NCT01378130
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Retinal Disease
Finasteride for Chronic Central Serous Chorioretinopathy
Background: Central serous chorioretinopathy (CSC) is a disease that causes fluid to collect under the retina. It affects the macula, which is in the center of the retina and is needed for sharp, clear vision.
- Trial name
- NCT01585441
- Testing
- Finasteride
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Eye Institute (NEI)
Central Serous Chorioretinopathy
High-dose Antioxidants for Central Serous Chorioretinopathy
Central serous chorioretinopathy (CSC) is the serous neurosensory detachment that usually involves the macular area. It is common in patients between 30-50 years old and effects male more often than female with the ratio of 5-10.
- Trial name
- NCT00963131
- Testing
- antioxidants tablets
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Prince of Songkla University
Diabetic Retinopathy, Retinal Vein Occlusion
Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus Photograph
Blindness can be caused by many ocular diseases, such as diabetic retinopathy, retinal vein occlusion, age-related macular degeneration, pathologic myopia and glaucoma.
- Conditions
- Diabetic Retinopathy, Retinal Vein Occlusion, Retinal Artery Occlusion, Central Serous Chorioretinopathy
- Trial name
- NCT04723160
- Testing
- Software assisted imaging diagnosis
- Where
- 5 sites in China
- Volunteers
- 748 people, healthy volunteers welcome
- Sponsor
- Visionary Intelligence Ltd.
Chorioretinopathy, Central Serous
Crocin Supplementation in CSCR
Preclinical and clinical evidence support the protective effect of crocin on different pathologic pathways involved in central serous chorioretinopathy (CSCR).
- Trial name
- NCT04936490
- Testing
- Crocin
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Shiraz University of Medical Sciences
Central Serous Chorioretinopathy
Optical Coherence Tomography Angiography (OCT-A) and Central Serous Chorioretinopathy (CSC)
Optical Coherence Tomography Angiography (OCT-A) is a noninvasive imaging technique that allows one to see blood vessels in the retina.
- Trial name
- OPACITY (NCT03950089)
- Testing
- Optical Coherence Tomography Angiography (OCT-A)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon