Clinical trials: Chorioretinopathy, Central Serous
Chronic Central Serous Chorioretinopathy
Microperimetric Evaluation After Half-dose Photodynamic Therapy for Chronic Central Serous Chorioretinopathy
A half-dose photodynamic therapy, a relative new treatment, has been widely performed to treat central serous chorioretinopathy.
- Trial name
- NCT01434095
- Testing
- half-dose photodynamic therapy
- Where
- Japan
- Volunteers
- 16 people
- Sponsor
- Surugadai Nihon University Hospital
Central Serous Chorioretinopathy, Selective Retina Therapy
Selective Retina Therapy (SRT) in Patients With Idiopathic Central Serous Retinopathy
The purpose of this study is to evaluate the efficacy of Selective Retina Therapy (SRT) for treating acute idiopathic central serous chorioretinopathy (ICSC).
- Trial name
- NCT00987077
- Testing
- Selective Retina Therapy (SRT)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Kiel
Retinal Disease
Pilot Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous Chorioretinopathy
Central serous chorioretinopathy (CSC) is a retinal disorder characterized by an accumulation of serous fluid under the retina. Although acute CSC tends to spontaneously resolve on its own with minimal sequelae, chronic CSC tends…
- Trial name
- NCT00837252
- Testing
- Finasteride
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Eye Institute (NEI)
Central Serous Chorioretinopathy
Intravitreal Ranibizumab Treatment of Central Serous Chorioretinopathy
The purpose of this study is to examine the effects of Lucentis for active Central Serous Chorioretinopathy.
- Trial name
- NCT00403325
- Testing
- rhuFab V2 [ranibizumab] ( Lucentis )
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Vitreous -Retina- Macula Consultants of New York
Macula Edema, Radiation Retinopathy
Phase I Study of Episcleral Celecoxib for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole
This phase I trial will assess primarily the safety and secondarily the anti-inflammatory and anti-neovascular effect of Episcleral Celecoxib in patients suffering from macular edema and other inflammatory disorders of the…
- Conditions
- Macula Edema, Radiation Retinopathy, Branch Retinal Vein Occlusion, Epiretinal Membrane
- Trial name
- NCT04120636
- Testing
- Episcleral Celecoxib
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Targeted Therapy Technologies, LLC
Central Serous Chorioretinopathy, Melatonin
Evaluating Efficacy and Safety of Oral Melatonin in Acute Central Serous Chorioretinopathy
The goal of this clinical trial is to learn if oral melatonin can enhance visual acuity and central macular thickness in central serous chorioretinopathy (CSCR) in adults. The main questions it aims to answer are: 1.
- Conditions
- Central Serous Chorioretinopathy, Melatonin, Ocular Diseases, Visual Acuity
- Trial name
- NCT06809751
- Testing
- melatonin 3mg
- Volunteers
- 48 people
- Sponsor
- Mohsen Pourazizi
Chronic Central Serous Chorioretinopathy
Photodynamic Therapy Using Verteporfin for Treatment of Chronic Central Serous Chorioretinopathy (CSC)
Central serous choroidal (CSC) retinopathy is a disease of the macula characterized by exudation of fluid under the retina localized to the posterior pole as well as loss of vision.
- Trial name
- NCT00211445
- Testing
- Photodynamic Therapy with Verteporfin, verteporfin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Manhattan Eye, Ear & Throat Hospital
Chronic Central Serous Chorioretinopathy
Pseudo-PDT in Central Serous Chorioretinopathy
Acute central serous chorioretinopathy (CSC) is a common disorder in middle-aged patients, characterized by serous retinal detachment in the macular region.
- Trial name
- NCT02799992
- Testing
- 689 nm Laser Treatment of the Macula, Half Dose Photodynamic Therapy
- Volunteers
- 22 people
- Sponsor
- Università degli Studi di Brescia
Central Serous Chorioretinopathy
Choroidal Blood Flow in Acute and Chronic Central Serous Chorioretinopathy
Patients with central serous chorioretinopathy (CSC) will be monitored with laser speckle flow graphy (LSFG), swept source optical coherence tomography (SS-OCT) and SS-OCT angiography (SS-OCTA).
- Trial name
- NCT05589974
- Testing
- Verteporfin
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Helse Stavanger HF
Chronic Central Serous Chorioretinopathy
Photodynamic Therapy Versus Eplerenone: Treatment Trial for Chronic Central Serous Chorioretinopathy
Chronic central serous chorioretinopathy (cCSC) is a relatively frequently occurring eye disease that is often diagnosed in patients in the professionally active age range.
- Trial name
- SPECT (NCT03079141)
- Testing
- Eplerenone, Photodynamic therapy
- Where
- 3 sites in Netherlands
- Volunteers
- 107 people
- Sponsor
- Leiden University Medical Center
Central Serous Chorioretinopathy
Methotrexate for Central Serous Chorioretinopathy Treatment Trial
Central serous chorioretinopathy (CSC) is a disease of unknown origin however multiple reports have indicated correlation of appearance of CSC with exposure to exogenous or elevated levels of endogenous corticosteroid.
- Trial name
- MTX4CSC (NCT01633983)
- Testing
- Methotrexate, Delayed treatment
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Edward Averbukh
Central Serous Chorioretinopathy
Study on the Use of Micropulse Laser to Treat Central Serous Chorioretinopathy
The investigators hypothesis is that using the micropulse laser in patient with Central Serous Chorioretinopathy (CSC) will prompt resolution of CSC and will be effective in significantly minimizing visual recovery time from this…
- Trial name
- NCT01982383
- Testing
- Micropulse Laser Treatment, No treatment
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- George Washington University
Central Serous Chorioretinopathy
Two Patterns of Micropulse Laser in the Treatment of Chronic Central Serous Chorioretinopathy
Central serous chorioretinopathy (CSC) is a common eye disease mainly involving the macular area, causing central visual acuity loss.
- Trial name
- NCT05687422
- Testing
- 100μm laser spot diameter micropulse laser, 200μm laser spot diameter micropulse laser
- Volunteers
- 50 people
- Sponsor
- Beijing Hospital
Age- Related Macular Degeneration, Diabetic Retinopathy
A Case-Control Study Revealing Intraocular Microenvironment Characteristics in Patients With Ocular Diseases Based on Multi-Omics Analysis
This project systematically investigates the role of the intraocular microbiome in various ocular diseases, including age-related macular degeneration, diabetic retinopathy, and cataracts.
- Conditions
- Age- Related Macular Degeneration, Diabetic Retinopathy, Retinal Vein Occlusion, Central Serous Chorioretinopathy
- Trial name
- NCT07897513
- Testing
- Not applicable- observational study
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Central Serous Chorioretinopathy
Mindfulness for Central Serous Chorioretinopathy
The primary goal of this clinical trial is to test whether a mindfulness-based treatment is effective at shortening the duration of, and improving the features of, central serous chorioretinopathy in adults.
- Trial name
- MIND'S EYE (NCT07767058)
- Testing
- Mindfulness
- Where
- 6 sites in United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Chronic Central Serous Chorioretinopathy
Steroid Eye Drops in Chronic Central Serous Chorioretinopathy
In this pilot study the effect and safety of the use of steroid eye drops in chronic central serous chorioretinopathy (cCSC) will be evaluated. The study is conducted as a randomized single-blind placebo-controlled trial.
- Trial name
- PICS (NCT05633576)
- Testing
- steroid eye drops
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Radboud University Medical Center
Diabetic Retinopathy, Retinal Vein Occlusion
Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus Photograph
Blindness can be caused by many ocular diseases, such as diabetic retinopathy, retinal vein occlusion, age-related macular degeneration, pathologic myopia and glaucoma.
- Conditions
- Diabetic Retinopathy, Retinal Vein Occlusion, Retinal Artery Occlusion, Central Serous Chorioretinopathy
- Trial name
- NCT04723160
- Testing
- Software assisted imaging diagnosis
- Where
- 5 sites in China
- Volunteers
- 748 people, healthy volunteers welcome
- Sponsor
- Visionary Intelligence Ltd.
Central Serous Chorioretinopathy
The Safety & Efficacy of Intravitreal Aflibercept Injection in Patients With Persistent Central Serous Chorioretinopathy
A preliminary study to determine the safety and efficacy of intravitreal aflibercept injection in patients with persistent central serous chorioretinopathy.
- Trial name
- CONTAIN (NCT01710332)
- Testing
- Intravitreal Aflibercept Injection
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Wills Eye
Central Serous Chorioretinopathy
Short-Term Oral Mifepristone for Central Serous Chorioretinopathy
The goal of the study is to assess the efficacy and safety of mifepristone 300 or 900-mg once-daily dosing by mouth for 4 weeks in patients with central serous chorioretinopathy.
- Trial name
- STOMP-CSC (NCT02354170)
- Testing
- Mifepristone
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Roger Goldberg, M.D., MBA
Retinal Disease
Extension Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous Chorioretinopathy
Background: Central serous chorioretinopathy (CSC) is a disease in which fluid accumulates under the retina and can cause distorted vision.
- Trial name
- CSC-Ext (NCT01227993)
- Testing
- Finasteride
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Eye Institute (NEI)