Clinical trials: Chorioretinopathy
Central Serous Chorioretinopathy (CSC)
Faricimab for Chronic Central Serous Chorioretinopathy: A Randomized Sham-Controlled Trial
Dysregulation of the Angiopoietin-2 (Ang-2)/Tyrosine kinase with Immunoglobulin-like and EGF-like domains 2 (Tie-2) signaling pathway has been implicated in choroidal vascular instability and RPE dysfunction in Central serous…
- Trial name
- NCT07681167
- Testing
- Faricimab
- Volunteers
- 50 people
- Sponsor
- Singapore National Eye Centre
Central Serous Chorioretinopathy, Selective Retina Therapy
Selective Retina Therapy (SRT) in Patients With Idiopathic Central Serous Retinopathy
The purpose of this study is to evaluate the efficacy of Selective Retina Therapy (SRT) for treating acute idiopathic central serous chorioretinopathy (ICSC).
- Trial name
- NCT00987077
- Testing
- Selective Retina Therapy (SRT)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Kiel
Central Serous Chorioretinopathy
Central Serous Chorioretinopathy and Micropulse Laser Treatment
To evaluate choroidal and choriocapillaris changes in patients with central serous chorioretinopathy, undergone sub threshold micropulse laser treatment, following any improvement with conservative therapy with Acetazolamide…
- Trial name
- LEVEO (NCT06346405)
- Testing
- Subthreshold Micropulse Laser Treatment
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Retinal Disease
Evaluation and Treatment of Patients With Retinal Disease
This study offers evaluation and treatment for patients with certain diseases of the retina (the layer of light-sensitive tissue that lines the inside of the eyeball).
- Trial name
- NCT00005784
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- National Eye Institute (NEI)
Anterior Uveitis (AU), Birdshot Chorioretinitis
Quantification & Classification of Inflammatory Cells in Uveitis Using OCT
The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography (OCT) to develop an unbiased, standard method of counting and categorizing the various types of…
- Conditions
- Anterior Uveitis (AU), Birdshot Chorioretinitis, Behcet Disease, Herpes Simplex Virus
- Trial name
- NCT07065747
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Acute Central Serous Retinopathy With Subretinal Fluid
Subthreshold Micropulse Laser Treatment of Acute Central Serous Chorioretinopathy
To evaluate the efficacy and safety of 532 nm green subthreshold micropulse laser (GSML) as a treatment for acute central serous chorioretinopathy (CSCR).
- Trial name
- NCT05447117
- Testing
- Micropulse laser
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Minia University
Central Serous Chorioretinopathy
Mindfulness for Central Serous Chorioretinopathy
The primary goal of this clinical trial is to test whether a mindfulness-based treatment is effective at shortening the duration of, and improving the features of, central serous chorioretinopathy in adults.
- Trial name
- MIND'S EYE (NCT07767058)
- Testing
- Mindfulness
- Where
- 6 sites in United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Central Serous Chorioretinopathy
Bevacizumab Versus Micropulse in Central Serous Chorioretinopathy (CSC)
The purpose of this study is to evaluate the clinical efficacy of an initial subthreshold retinal micropulselasercoagulation versus a single intravitreal 1.5mg bevacizumab injection in central serous choriretinopathy, as the…
- Trial name
- NCT00802906
- Testing
- subthreshold micropulselaser, bevacizumab
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Central Serous Chorioretinopathy
Selective Retina Therapy With 'R:GEN' in Patients With Central Serous Chorioretinopathy
The purpose of this clinical study is to evaluate the efficacy and safety of selective retina therapy (SRT) using R:GEN, an approved laser device, in patients with central serous chorioretinopathy.
- Trial name
- NCT03758963
- Testing
- R:GEN Selective Retina Therapy
- Where
- 6 sites in South Korea
- Volunteers
- 63 people
- Sponsor
- CynosureLutronic
Central Serous Chorioretinopathy
The Safety & Efficacy of Intravitreal Aflibercept Injection in Patients With Persistent Central Serous Chorioretinopathy
A preliminary study to determine the safety and efficacy of intravitreal aflibercept injection in patients with persistent central serous chorioretinopathy.
- Trial name
- CONTAIN (NCT01710332)
- Testing
- Intravitreal Aflibercept Injection
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Wills Eye
Central Serous Chorioretinopathy
Intravitreal Bevacizumab for the Treatment of Central Serous Chorioretinopathy
Central serous chorioretinopathy (CSC) has been known since it was first described by Von Graefe and termed "idiopathic detachment of the macula" in 1866, is a well-characterized disorder leading to serous neurosensory elevation…
- Trial name
- NCT00418431
- Testing
- Intravitreal injection of Bevacizumab
- Where
- Mexico
- Sponsor
- Asociación para Evitar la Ceguera en México
Non-infectious Uveitis
Safety and Efficacy of AIN457 in Noninfectious Uveitis
This study was performed to evaluate the efficacy and safety of AIN457 for patients with active uveitis that requires systemic immunosuppression.
- Trial name
- NCT00685399
- Testing
- AIN457, AIN 457
- Where
- 23 sites in United States, Germany
- Volunteers
- 76 people
- Sponsor
- Novartis Pharmaceuticals
Age Related Macular Degeneration, Choroidal Neovascularization
Genetic Analysis of Chronic Central Serous Chorioretinopathy Masquerading as Neovascular AMD
The study will be designed as a case control evaluation to compare the genetic profiles of three groups of patients categorized according to diagnosis.
- Conditions
- Age Related Macular Degeneration, Choroidal Neovascularization, Central Serous Chorioretinopathy
- Trial name
- NCT01880788
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Sequenom, Inc.
Central Serous Chorioretinopathy
Two Patterns of Micropulse Laser in the Treatment of Chronic Central Serous Chorioretinopathy
Central serous chorioretinopathy (CSC) is a common eye disease mainly involving the macular area, causing central visual acuity loss.
- Trial name
- NCT05687422
- Testing
- 100μm laser spot diameter micropulse laser, 200μm laser spot diameter micropulse laser
- Volunteers
- 50 people
- Sponsor
- Beijing Hospital
Chronic Central Serous Chorioretinopathy
Treatment of Chronic Central Serous Chorioretinopathy With Open-Label Anecortave Acetate
Investigation to evaluate Anecortave Acetate in the treatment of chronic central serous chorioretinopathy
- Trial name
- CSC-AA (NCT00489840)
- Testing
- Anecortave Acetate Sterile suspension 15 mg, Anecortave Acetate
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Manhattan Eye, Ear & Throat Hospital
Central Serous Chorioretinopathy
Methotrexate for Central Serous Chorioretinopathy Treatment Trial
Central serous chorioretinopathy (CSC) is a disease of unknown origin however multiple reports have indicated correlation of appearance of CSC with exposure to exogenous or elevated levels of endogenous corticosteroid.
- Trial name
- MTX4CSC (NCT01633983)
- Testing
- Methotrexate, Delayed treatment
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Edward Averbukh
Central Serous Chorioretinopathy, Micropulse Laser
Combination of Micropulse Laser With or Without Photodynamic Therapy for Chronic Central Serous Chorioretinopathy
In this study, patients with chronic central serous chorioretinopathy who were treated by micropulse laser alone or micropulse laser combined with photodynamic therapy without drugs are retrospectively included.
- Conditions
- Central Serous Chorioretinopathy, Micropulse Laser, Photodynamic Therapy
- Trial name
- NCT06468540
- Volunteers
- 60 people
- Sponsor
- Beijing Hospital
Chronic Central Serous Chorioretinopathy
Ranibizumab Versus Low-fluence Photodynamic Therapy in the Treatment of Chronic Central Serous Chorioretinopathy
The purpose of this study is to compare the efficacy and safety of intravitreal ranibizumab injection versus low-fluence PDT in the treatment of chronic CSC.
- Trial name
- NCT01325181
- Testing
- Verteporfin, ranibizumab
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Jang Won Heo
Retinal Disease
Pilot Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous Chorioretinopathy
Central serous chorioretinopathy (CSC) is a retinal disorder characterized by an accumulation of serous fluid under the retina. Although acute CSC tends to spontaneously resolve on its own with minimal sequelae, chronic CSC tends…
- Trial name
- NCT00837252
- Testing
- Finasteride
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Eye Institute (NEI)
Birdshot Chorioretinopathy, Posterior Uveitis
Birdshot Chorioretinopathy : Prospective Follow-up and Immunogenetic Studies(CO-BIRD)
The purpose of this study is twofold: 1. To analyze the clinical features of a cohort of patients with birdshot chorioretinopathy (BCR), an inflammatory bilateral ocular disease, affecting the choroid and the retina.
- Trial name
- CO-BIRD (NCT05153057)
- Testing
- Observational study
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris