Clinical trials: Chorioretinopathy
Choroidal Ischemia, Vitelliform Macular Dystrophy
Sildenafil for Treatment of Choroidal Ischemia
The hypothesis of this study is to determine if there is a benefit afforded by the use of systemic Sildenafil to patients with choroidal and retinal degenerations and dystrophies, such as vitelliform degeneration, dry and…
- Conditions
- Choroidal Ischemia, Vitelliform Macular Dystrophy, Age-related Macular Degeneration, Central Serous Retinopathy
- Trial name
- NCT04356716
- Testing
- Sildenafil, Standard of Care Sildenafil, Ocular Coherence Tomography-Angiography (OCT-A)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Columbia University
Retinal Disease
Extension Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous Chorioretinopathy
Background: Central serous chorioretinopathy (CSC) is a disease in which fluid accumulates under the retina and can cause distorted vision.
- Trial name
- CSC-Ext (NCT01227993)
- Testing
- Finasteride
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Eye Institute (NEI)
Non-infectious Uveitis
Safety and Efficacy of AIN457 in Noninfectious Uveitis
This study was performed to evaluate the efficacy and safety of AIN457 for patients with active uveitis that requires systemic immunosuppression.
- Trial name
- NCT00685399
- Testing
- AIN457, AIN 457
- Where
- 23 sites in United States, Germany
- Volunteers
- 76 people
- Sponsor
- Novartis Pharmaceuticals
Age-Related Macular Degeneration, Geographic Atrophy
Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO
To conduct a precision study to assess the microperimetry function of the Spectral OCT/SLO. The study will assess variability across measurements taken by three different operator-device configuration across clinical sites…
- Conditions
- Age-Related Macular Degeneration, Geographic Atrophy, Diabetic Retinopathy, Macular Edema
- Trial name
- NCT01692938
- Where
- 3 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Optos, PLC
Central Serous Chorioretinopathy
Study on the Use of Micropulse Laser to Treat Central Serous Chorioretinopathy
The investigators hypothesis is that using the micropulse laser in patient with Central Serous Chorioretinopathy (CSC) will prompt resolution of CSC and will be effective in significantly minimizing visual recovery time from this…
- Trial name
- NCT01982383
- Testing
- Micropulse Laser Treatment, No treatment
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- George Washington University
Central Serous Chorioretinopathy
The Safety & Efficacy of Intravitreal Aflibercept Injection in Patients With Persistent Central Serous Chorioretinopathy
A preliminary study to determine the safety and efficacy of intravitreal aflibercept injection in patients with persistent central serous chorioretinopathy.
- Trial name
- CONTAIN (NCT01710332)
- Testing
- Intravitreal Aflibercept Injection
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Wills Eye
Retinal Disease
Pilot Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous Chorioretinopathy
Central serous chorioretinopathy (CSC) is a retinal disorder characterized by an accumulation of serous fluid under the retina. Although acute CSC tends to spontaneously resolve on its own with minimal sequelae, chronic CSC tends…
- Trial name
- NCT00837252
- Testing
- Finasteride
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Eye Institute (NEI)
Chronic Central Serous Chorioretinopathy
Ranibizumab Versus Low-fluence Photodynamic Therapy in the Treatment of Chronic Central Serous Chorioretinopathy
The purpose of this study is to compare the efficacy and safety of intravitreal ranibizumab injection versus low-fluence PDT in the treatment of chronic CSC.
- Trial name
- NCT01325181
- Testing
- Verteporfin, ranibizumab
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Jang Won Heo
Retinal Disease
Finasteride for Chronic Central Serous Chorioretinopathy
Background: Central serous chorioretinopathy (CSC) is a disease that causes fluid to collect under the retina. It affects the macula, which is in the center of the retina and is needed for sharp, clear vision.
- Trial name
- NCT01585441
- Testing
- Finasteride
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Eye Institute (NEI)
Age-Related Macular Degeneration, Diabetic Retinopathy
Comfortable and Stabilizing Chin & Forehead Rest Attachment for Slit Lamp Configurations
In this study, participants will be imaged using two Optical Coherence Tomography (OCT) devices: device N, a standard conventional OCT device with an invention (comfortable chin and forehead rest that can be adjusted to fit each…
- Conditions
- Age-Related Macular Degeneration, Diabetic Retinopathy, Central Serous Chorioretinopathy, Glaucoma
- Trial name
- NCT05686421
- Testing
- OCT Imaging Using Device N, OCT Imaging Using Device C
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Retinal Disease, Macular Disease
Topical Interferon Gamma-1b for Central Serous Chorioretinopathy
Background: In the eye disease central serous chorioretinopathy (CSC), fluid collects under the retina at the back of the eye. CSC can resolve on its own, but in some people it lasts for several months or can come back.
- Trial name
- NCT01468337
- Testing
- Interferon gamma-1b
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Eye Institute (NEI)
Central Serous Chorioretinopathy
Eplerenone for Central Serous Chorioretinopathy
The goal of the study is to examine the short-term effects and safety of a systemic anti-aldosterone medication, eplerenone, in a small group of patients with central serous chorioretinopathy (CSCR).
- Trial name
- NCT01822561
- Testing
- Eplerenone 50mg
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Tufts Medical Center
Central Serous Chorioretinopathy
Comparison of Multifocal Electroretinogram Assessment in Chronic Central Serous Chorioretinopathy (CSC) Between Laser Treatment Group and Photodynamic Therapy Group in Chronic Central Serous Chorioretinopathy
This study is a comparison of multifocal electroretinogram assessment between the laser treatment group and the photodynamic therapy group in chronic central serous chorioretinopathy.
- Trial name
- NCT00803517
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Samsung Medical Center
Central Serous Chorioretinopathy
Eplerenone for the Treatment of Central Serous Chorioretinopathy
To test the effect oral eplerenone versus placebo in patients with central serious chorioretinopathy .
- Trial name
- NCT01990677
- Testing
- 25mg Eplerenone
- Where
- 10 sites in United States
- Volunteers
- 108 people
- Sponsor
- Wills Eye