Clinical trials: Choroidal Thickness
PCOS
Eye Evaluation in Patients With PCOS
To evaluate the macular, retinal nerve fiber layer (RNFL) and choroidal thickness alterations by using spectral-domain optical coherence tomography (SD-OCT) in polycystic ovary syndrome (PCOS) and to compare them with healthy…
- Trial name
- NCT01950832
- Testing
- Investigating clinically normal patients with optic coherence tomography
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Gökhan Açmaz
Emmetropia, Myopia
Effects of Light on the Choroid and Pupil
Monochromatic light creates longitudinal chromatic aberration, with short wavelength blue light forming a focal point in front of the retina and long wavelength red light forming a focal point behind the retina.
- Trial name
- NCT05852782
- Testing
- White Light therapy, Blue light therapy, Red light therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Houston
Healthy
Study of the Choroidal and Retinal Thickness in Relation to Axial Length.
The aim of the study is the non-invasive morphological evaluation of the choroid and the retina in relation to the length of the eyeball in healthy, young man and women.
- Trial name
- CHORAL (NCT03377075)
- Testing
- AL measurement, OCT
- Where
- Hungary
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Optical Coherence Tomography, Diabetic Retinopathy
A Longitudinal Study of Choroidal Changes After Cataract Surgery in Eyes With Diabetic Retinopathy
To determine the influence of phacoemulsification on choroidal vasculature in patients with diabetic retinopathy (DR) undergoing cataract surgery
- Conditions
- Optical Coherence Tomography, Diabetic Retinopathy, Choroid
- Trial name
- NCT04499768
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Ruijin Hospital
Benign Prostatic Hyperplasia, Silodosin
Pupil Size and Choroidal Thickness Changes With Tamsulosin vs. Silodosin in Benign Prostatic Hyperplasia Patients
Benign prostatic hyperplasia (BPH) is a common disease in men and is treated with alpha-blockers, particularly tamsulosin and silodosin.
- Conditions
- Benign Prostatic Hyperplasia, Silodosin, Tamsulosin, Choroid
- Trial name
- NCT07743060
- Testing
- tamsulosin 0.4mg, Silodosin 8 mg
- Volunteers
- 40 people
- Sponsor
- Mohsen Pourazizi
Glaucoma, Open-Angle
The Effect of Pseudoexfoliation on Choroidal Thickness in Open Angle Glaucoma
Purpose: To investigate the effect of pseudoexfoliation (PEX) on choroidal thickness in primary open-angle glaucoma (POAG). Methods: This prospective, randomized study included 30 POAG patients and 30 PEX glaucoma patients with…
- Trial name
- NCT03373942
- Testing
- Choroidal thickness measurements with SD-OCT device
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Emine Deniz Egrilmez
Dry Eye, Choroidal Thickness
Systemic Isotretinoin Therapy and Eye
The dermatologist created a treatment plan for participants diagnosed with acne using medications containing vitamin A. While this medication has many benefits for the skin, it also has various side effects affecting many other…
- Conditions
- Dry Eye, Choroidal Thickness, Retinal Vascularisation, Acne Cystic
- Trial name
- NCT07675460
- Testing
- Isotretinoin (13-cis-retinoic acid)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Demet Mutlu
Choroidal Thickness, Open Angle Glaucoma
Changes in Choroidal Thickness After Non Penetrating Deep Sclerectomy
Prospective and observational study to determine if choroidal thickness increases after non penetrating deep sclerectomy in patients with open angle glaucoma
- Conditions
- Choroidal Thickness, Open Angle Glaucoma, Non Penetrating Deep Sclerectomy
- Trial name
- NCT03160690
- Testing
- Non penetrating deep sclerectomy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Germans Trias i Pujol Hospital
Myopia; Refractive Error
Measuring Changes In Choroidal Thickness Induced By Prototype Soft Contact Lenses Worn For 1 Hour
The objective of the study is to evaluate the short-term change in choroidal thickness induced by 3 prototype soft contact lenses for people with myopia.
- Trial name
- ARCTIC (NCT07155551)
- Testing
- Lens A, Lens B, Lens C
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Myoptechs, Inc
Optic Nerve Disorders
Choroidal Thickness in Optic Neuropathy
This study plans to learn more about the thickness of the choroid in patients with optic neuropathy. The choroid is a layer of blood vessels that supplies oxygen and nourishment to the outer layers of the retina.
- Trial name
- NCT02382627
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Colorado, Denver
Choroid Disease, Hypertension Ocular
Study of Changes in Retrofoveolar Choroidal Thickness During Aerobic Exercise
Study the change of retrofoveolar choroidal thickness measured by optical coherence tomography during aerobic exercise inducing an increase in systolic blood pressure in healthy subjects.Ten healthy participants will perform an…
- Trial name
- MOPAS (NCT03532867)
- Testing
- Examination of pressures before stopping the exercise, Examination of pressure during the exercise, Examination of pressures after stopping the exercise
- Where
- France
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Nearsightedness
Effect of Defocus in Soft Contact Lenses on Internal Retinal Vascularization
The purpose of this study is to gain a better understanding of the retinal vascular changes that occur in response to the optical effect of a myopic defocus daily disposable soft contact lens (MDSL) in a group of healthy young…
- Trial name
- NCT06527274
- Testing
- Experimental: Myopic defocus soft lens design (MDSL), Active Comparator: Single vision soft lens design (SVSL
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Myopia
Change in Choroidal Thickness of Myopic Eyes With a Myopia Control Contact Lens
In this study, the direct effect of the MiSight contact lens (Cooper Vision), a daily disposable contact lens recently approved in Germany for the treatment of myopia, will be investigated.
- Trial name
- NCT06636019
- Testing
- Myopia control contact lens
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital Augsburg
Myopia
Exploratory Study on the Effect of SAT-001 on Choroidal Thickness in Pediatric Myopia Patients
This clinical trial aims to exploratively compare and evaluate the structural changes in the eye (specifically changes in choroidal thickness) pre- and post-treatment of the investigational medical devices ('SAT-001' and…
- Trial name
- NCT06729723
- Testing
- SAT-001, modified SAT-001
- Where
- 2 sites in South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- S-Alpha Therapeutics, Inc.
Beta-Thalassemia
Choroidal Thickness in Beta-thalassemia Patients
The purpose of this study is to examine choroidal thickness in beta-thalassemia patients and compare it to the one of healthy controls.
- Trial name
- NCT04067258
- Testing
- EDI-OCT
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital of Patras
Age-related Macular Degeneration
Effects of Sildenafil on Choroidal Thickness in AMD
Choroidal thinning has been hypothesized to partake in the pathogenesis of age-related macular degeneration (AMD), but it is not known if increasing choroidal thickness may potentially alter the disease course.
- Trial name
- NCT01830790
- Testing
- Sildenafil citrate
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Duke University
Choroidal Thickness
Choroidal Thickness Association With Primary Angle Closure
A chinese study shows that chinese population eyes with a primary angle closure have a greater choroidal thickness than normal eyes.The increase of choroidal thickness would be associated to this primary angle closure.
- Trial name
- NCT03050073
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Myopia Progression, Axial Length, Eye
Low Dose Atropine Eye Drops in Myopic Egyptian Children
Previous Studies reported that low concentration atropine eye drops may be effective in increasing the choroidal blood flow and thickness and this slows myopia progression.
- Conditions
- Myopia Progression, Axial Length, Eye, Sclera Thickness
- Trial name
- LAMP (NCT06265454)
- Testing
- low dose atropine eye drops
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Refractive Errors, Accommodation Disorder
Choroidal Thickness Change in Response to Physiological and Refractive Changes
There is a great need for precise and repeatable measurements of the choroidal thickness. Including the diurnal physiological changes, accommodation and refractive error impact on those measurements.
- Trial name
- NCT03906279
- Where
- Poland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Wrocław University of Science and Technology
Myopia
The Effects of Low Dose Atropine on Choroidal Thickness
Atropine eye drops are considered to be an effective form of myopia control in human eyes. However, the mechanism by which it exerts it effects are not fully understood.
- Trial name
- NCT03544827
- Testing
- Atropine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry