Clinical trials: Choroidal Thickness
Glaucoma Patients and Healthy Controls
Choroidal Thickness in Glaucoma Patients and Healthy Controls
With the new software tool (EDI, enhanced depth imaging) of the Spectralis® spectral-domain optical coherence tomography (SD-OCT) it is possible to visualize and measure the choroidal thickness.
- Trial name
- NCT01293474
- Testing
- Spectralis® SD-OCT, Heidelberg Engineering GmbH, H
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Choroid Disease, Diabetes Mellitus
Measuring Choroidal Thickness Using Optical Coherence Tomography
To compare the choroidal thickness in eyes of diabetic patients with eyes of age matched controls using optical coherence tomography.
- Trial name
- NCT06272851
- Testing
- optical coherence tomography
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Assiut University
Glaucoma
Morphometric Markers of the Effectiveness of Micropulse Cyclophotocoagulation
This prospective study aims to evaluate morphometric markers of treatment response following micropulse transscleral cyclophotocoagulation (MP-CPC) in patients with glaucoma.
- Trial name
- MMEMC (NCT07592923)
- Testing
- MicroPulse transscleral cyclophotocoagulation, Conventional transscleral cyclophotocoagulation
- Where
- Kazakhstan
- Volunteers
- 20 people
- Sponsor
- Kazakh Eye Research Institute
Chronic Mechanical Neck Pain
Acute Effects of Cervical Manual Therapy on Eye Blood Flow
This study evaluates the acute effects of cervical manual therapy on retinal and choroidal microvascular perfusion using optical coherence tomography angiography (OCTA).
- Trial name
- CERVICAL-OCTA (NCT07688707)
- Testing
- Cervical Manual Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Yuzuncu Yil University
Diabetes Mellitus, Type 2, Diabetic Retinopathy
Choroidal and Retinal Changes After RLRL Therapy in Diabetes and Diabetic Retinopathy
The choroidal thickness was found to be thinner in diabetic eyes without retinopathy compared to healthy eyes, thus choroidal thickness might be an important parameter for the development of diabetic retinopathy in diabetic eyes…
- Trial name
- NCT05773209
- Testing
- RLRL device
- Volunteers
- 58 people
- Sponsor
- The Second People's Hospital of Foshan
Healthy
Choroidal Thickness During Changes in Intraocular Pressure and Arterial Blood Pressure
Age-related macular degeneration (AMD) and glaucoma are among the leading causes of blindness in the western world. Elevated intraocular pressure (IOP) is a well known major risk factor for glaucoma.
- Trial name
- NCT01333891
- Testing
- Phenylephrine, Sodium-Nitroprusside, Suction Cup
- Where
- Austria
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Benign Prostatic Hyperplasia, Pupil Anomaly
The Effects of α-adrenergic Receptor Antagonists on Choroid and Pupil
It was aimed to evaluate and investigate the effects of tamsulosin hydrochloride, has preferential selectivity for the α1A receptor in the prostat versus the α1B receptor in the blood vessels, and alfuzosin hydrochloride on…
- Conditions
- Benign Prostatic Hyperplasia, Pupil Anomaly, Choroid Disease
- Trial name
- NCT03144596
- Testing
- Alfuzosin Hydrochloride 10 MG, Tamsulosin Hydrochloride 0.4 MG
- Volunteers
- 63 people
- Sponsor
- Kocatepe University
Subfoveal Choroidal Thickness, Intravitreal
Subfoveal Choroidal Thickness and Visual Acuity After Intravitreal Injection of Ranibizumab in Diabetic Retinopathy
The aim of this study is to compare subfoveal choroidal thickness (SFCT) and the visual status before and after intravitreal injection of ranibizumab in diabetic macular edema (DME) with the use of 3D-OCT by enhanced depth…
- Conditions
- Subfoveal Choroidal Thickness, Intravitreal, Ranibizumab, Visual Acuity
- Trial name
- NCT06173245
- Testing
- Intravitreal injection of ranibizumab
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Egyptian Biomedical Research Network
Myopia
Choroidal Response to the Modified Defocus Incorporated Multiple Segments Spectacle Lenses
The goal of this study is to investigate the short-term changes in choroidal thickness and efficacy of the study spectacle lenses in children.
- Trial name
- NCT07547072
- Testing
- Modified Defocus Incorporated Multiple Segments lens (D1), Modified Defocus Incorporated Multiple Segments lens (D2)
- Where
- Hong Kong
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Glaucoma
The Effectiveness Of Home-Based Circuit Training On Eye Pressure And Eye Nerve Structures In Patients With Glaucoma
The goal of this randomised control trial is to learn about the effect of home based circuit training on patients with primary glaucoma. The main questions to answer are: 1.
- Trial name
- NCT07733388
- Testing
- Home-Based Circuit Training
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- Universiti Sains Malaysia
Pregnancy
Evaluation of Choroidal Thickness During Pregnancy Using Enhanced Depth Imaging Optical Coherence Tomography
The purpose of this study is to evaluate choroidal thickness and volume during the third trimester of pregnancy by comparison with a group of age-matched non-pregnant healthy group of women
- Trial name
- NCT02024048
- Testing
- OCT
- Where
- Portugal
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Gaia Hospital
COVID-19 Pandemic
Retinal and Choroidal Microvascular Parameters in School-age Children in a COVID-19 Infection Pandemic Peak in China
We designed this study to examine whether COVID-19 infection could lead to retinal and choroidal microvascular involvement in school-age children (6-18 years) in a pandemic peak in China.
- Trial name
- NCT05952466
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guangzhou First People's Hospital
High Myopia, Pregnancy Related
Physiologic Ocular Changes During Pregnancy in Women With High Myopia.
The prevalence of myopia is seemingly increasing, and it is one of the major causes of blindness. High myopia is defined as a refractive error with spherical equivalent exceeding -6 diopters and/or the axial length longer than…
- Trial name
- NCT04773574
- Testing
- Corneal topography, Optical coherence tomography (OCT) and Optical coherence tomography angiography (OCTA)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
ESRD
Choroidal Thickness in Myopes by SSOCT
Optical coherence tomography is a non-invasive and non-contact imaging modality that enables two-dimensional cross-sectional and three-dimensional volumetric imaging of tissue architecture.
- Trial name
- NCT03542448
- Testing
- Swept source optical coherence tomography
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Choroid
Study of the Choroidal Thickness Variations After Ingestion of RedBull® Energy Drink
The choroid is a richly vascularized conjunctive tissue, providing the nutritive elements to the pigmentary epithelium and the photoreceptors of the retina. It drains 80% of the eye's blood.
- Trial name
- REDCHO (NCT02856256)
- Testing
- RedBull® energy drink
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Endophthalmitis, Macula Edema
Evaluation of Macular Changes After Intracameral Moxifloxacin for Prevention of Endophthalmitis
The objective of this study is to evaluate the macular and choroidal thickness of patients submitted to intracameral moxifloxacin during the phacoemulsification surgery for endophthalmitis prophylaxis.
- Conditions
- Endophthalmitis, Macula Edema, Cataract
- Trial name
- NCT03363295
- Testing
- Moxifloxacin Injection
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Universidade Federal de Pernambuco
Strabismus, Retinal Thickening
Choroidal and Retinal Thickness Following Strabismus Surgery
Prospective study, conducted at Tanta University Ophthalmology Department Measurement of macular and choroidal thickness before and after strabismus surgery
- Trial name
- NCT04285177
- Testing
- Strabismus surgery
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Myopia, Refractive Error - Myopia
Minimum Power and Frequency of Repeated Low-level Red-light to Effectively Control Myopia Progression
To explore the minimum power and frequency of Repeated Low-level Red-light (RLRL) to control myopia progression in low-myopic children aged 8-10 years, and the rebound effect of low-myopic children after discontinuation of RLRL…
- Conditions
- Myopia, Refractive Error - Myopia, Choroidal Thickness, Retina
- Trial name
- NCT06717048
- Testing
- Repeated Low-level Red-light, Red LED
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Fish Oils
the Effects of Fish Oil Supplements on Choroidal Thickness and Blood Flow Perfusion in Children and Adolescents
The goal of this clinical trial is to test the effect of fish oil supplement in terms of vision in children and adolescents. The main question it aims to answer is: the differences in changes of choroidal thickness, choroidal…
- Trial name
- FOS (NCT06877494)
- Testing
- fish oil
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Choroidal Changes Post Short Term Exposure To Virtual Reality Devices
This is a prospective, randomized, controlled, contralateral eye, clinical study. The objective of the study is to determine the impact of Virtual Reality (VR) usage on choroidal thickness when viewed through a test display…
- Trial name
- MIRABILE (NCT04140877)
- Testing
- Visu
- Volunteers
- healthy volunteers welcome
- Sponsor
- Visu, Inc.