Clinical trials: Chromoendoscopy
Colonic Polyps
The Value of Polyp Surface Pattern Recognition in the Identification of Neoplasia: a Prospective Study
It is current practice to remove any polyps found during colonoscopy. This is because adenomatous polyps have the potential to turn into cancer.
- Trial name
- NCT01182623
- Testing
- Observation of surface patterns of polyps
- Where
- United Kingdom
- Volunteers
- 260 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Colorectal Neoplasms
Study of Narrow Band Imaging in the Characterization of Residual Neoplasia After Endoscopic Piecemeal Mucosal Resection
This study is designed to evaluate the diagnostic accuracy of Narrow Band Imaging (NBI) compared with High Definition White Light colonoscopy (WLE) for detection of residual neoplasia in subjects with piecemeal polypectomy scars.
- Trial name
- CROMOPIE (NCT02448693)
- Testing
- WLE, NBI
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Parc de Salut Mar
Ulcerative Colitis
Endomicroscopy in Ulcerative Colitis
This is a confirmatory, multicentric, prospective, randomized, controlled, single-blind study in subjects with long standing ulcerative colitis in clinical remission with indication for surveillance colonoscopy.
- Trial name
- NCT00659867
- Testing
- PENTAX EC-3870CIFK / EC-3870CILK confocal colonoscopes
- Where
- 5 sites in Germany, Italy
- Volunteers
- 182 people
- Sponsor
- PENTAX Europe GmbH
Chronic Diarrhoea, Lymphocytic Colitis
Usefulness of Chromoendoscopy in Diagnosing Microscopic Colitis
The purpose of this study is to determine whether chromoendoscopy using Indigo-Carmine dye spray is useful in diagnosing microscopic colitis among patients undergoing colonoscopy due to chronic watery diarrhea.
- Conditions
- Chronic Diarrhoea, Lymphocytic Colitis, Collagenous Colitis
- Trial name
- NCT01504048
- Testing
- Colonoscopy with Indigo-Carmine Chromoendoscopy
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Karolinska University Hospital
Colonic Polyp, Colonic Neoplasms
Chromoendoscopy for Serrated Polyposis Syndrome
Serrated polyposis syndrome (SPS) is the most common colorectal polyposis syndrome and is characterized by the combination of large and/or numerous serrated lesions (SLs) throughout the colorectum.
- Conditions
- Colonic Polyp, Colonic Neoplasms, Colonic Cancer
- Trial name
- SERRADA (NCT03476434)
- Testing
- chromoendoscopy with indigo carmine
- Volunteers
- 86 people
- Sponsor
- Hospital Universitario de Móstoles
Ulcerative Colitis, Crohn's Colitis
Chromoendoscopy for Dysplasia Detection in Chronic Inflammatory Bowel Disease
Patients with longstanding ulcerative colitis or crohn's disease in the large bowel have an increased risk of developing cancer.
- Trial name
- NCT01505842
- Testing
- Colonoscopy with Indigo-Carmine chromoendoscopy, Conventional white-light colonoscopy
- Where
- Sweden
- Volunteers
- 304 people
- Sponsor
- Karolinska University Hospital
Colorectal Neoplasms, Colonic Polyps
Evaluation of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for Detection and Optical Characterization of Colorectal Lesions: A Prospective Randomized Controlled Study
This prospective randomized controlled study aims to evaluate the diagnostic accuracy of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for detection and optical characterization of…
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Adenoma, Serrated Polyps
- Trial name
- INSIGHT (NCT07797361)
- Testing
- White Light Endoscopy, Versatile Intelligent Staining Technology, Spectral Flexible Imaging
- Where
- Brazil
- Volunteers
- 990 people
- Sponsor
- Alexandre Vontobel Padoin
Lynch Syndrome
High Definition White-Light Colonoscopy vs. Chromoendoscopy for Surveillance of Lynch Syndrome.
Adenomas in Lynch syndrome have an accelerated progression to colorectal cancer (CRC) which might occur despite a regular follow-up.
- Trial name
- EndoLynch (NCT02951390)
- Testing
- High-definition white-light endoscopy
- Where
- Spain
- Volunteers
- 280 people
- Sponsor
- Hospital Clinic of Barcelona
Familial Adenomatous Polyposis (FAP), Pouches, Ileoanal
Evaluation of the Ileo-anal Pouch in FAP (ENDOPOL)
This international, multi-centre randomised controlled trial will compare dye-based chromoendoscopy with virtual chromoendoscopy, using NBI/BLI, for adenoma detection during routine surveillance pouchoscopy in adults with…
- Trial name
- ENDOPOL (NCT07726771)
- Testing
- Chromoendoscopy (Indigo Carmine), Virtual Chromoendoscopy
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- London North West Healthcare NHS Trust
Barrett Esophagus, Barrett Metaplasia
Aceto-whitening in the Assessment of Gastrointestinal Neoplasia
Acetic acid chromoendoscopy is an established standard technique used to detect dysplasia within the gastrointestinal tract. Acetic acid spray helps to identify neoplasia by highlighting the surface pattern, highlighting the…
- Conditions
- Barrett Esophagus, Barrett Metaplasia, Barrett Oesophagitis With Dysplasia, Barrett Adenocarcinoma
- Trial name
- NCT01618643
- Testing
- Acetic acid chromoendoscopy
- Where
- United Kingdom
- Volunteers
- 197 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Lynch Syndrome
NBI Versus Indigo Carmine During Colonoscopy in Lynch Syndrome
This study compares two colonoscopy techniques (with Narrow Band Imaging versus with indigo carmine chromoendoscopy) in patients having Lynch Syndrome
- Trial name
- LYNCH-CHROMO (NCT02570516)
- Testing
- Colonoscopy
- Where
- 7 sites in France
- Volunteers
- 141 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Colitis, Colonic Dysplasia
Improved and Simplified Staining Technique for Dysplasia Detection in Colitis
Comparing chromoendoscopy to a digital staining technique and White light in patients with IBD attending scheduled surveillance colonoscopy
- Conditions
- Colitis, Colonic Dysplasia, Inflammatory Bowel Diseases, Colonoscopy
- Trial name
- IST-DDC (NCT06223347)
- Testing
- Chromoendoscopy
- Where
- Sweden
- Volunteers
- 106 people
- Sponsor
- Vastra Gotaland Region
Colorectal Polyp
Validation of the NICE Classification Using Pentax Chromoendoscopy
Colorectal cancer (CRC) is the most frequent gastrointestinal tumor and the second cause of cancer related death. Colonoscopy is currently the recommended method for detection of polyps and cancers in the colon.
- Trial name
- NCT03155308
- Testing
- Pentax chromoendoscopy (i-scan and Optical Enhancement)
- Where
- Ecuador
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Stomach Neoplasms, Metaplasia
Acetic Acid Chromoendoscopy to Judge Gastric Intestinal Metaplasia
The presence and the extent of gastric intestinal metaplasia(IM) is a good indicator of high risk group of gastric cancer. Many methods was developed to survey it, including multiple gastric biopsy or methylene blue…
- Trial name
- IM (NCT01499576)
- Testing
- Acetic acid chromoendoscopy
- Where
- South Korea
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Konyang University Hospital
Barretts Esophagus With Low Grade Dysplasia, Dysplasia
Acetic Acid for the Detection of Esophageal Neoplasms
Barrett's esophagus is a complication of chronic gastroesophageal reflux disease that occurs in up to 10% to 15% of patients with this pathology.
- Conditions
- Barretts Esophagus With Low Grade Dysplasia, Dysplasia, Intestinal Metaplasia
- Trial name
- NCT04054713
- Testing
- Acetic acid chromoendoscopy, Seattle protocol
- Where
- Mexico
- Volunteers
- 76 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Ulcerative Colitis, Dysplasia
Surveillance in Ulcerative Colitis: Narrow Band Image Versus Chromoendoscopy for High-risk Groups
The risk of colorectal cancer (CRC) is increased in patients having ulcerative colitis (UC). Patients with long-standing extensive colitis, concomitant primary sclerosing cholangitis, or previous history of dysplasia carry an…
- Trial name
- SUNRISE-High (NCT04257084)
- Testing
- chromoendoscopy with target biopsy; NBI with target biopsy
- Volunteers
- 188 people
- Sponsor
- Asan Medical Center
Non Erosive Reflux Disease, GERD
Minimal Injuries From Esophagus Detected by Optical Enhancement System™ Associated to Optical Magnification HD Scopes
White light endoscopy remains the gold standard technique to evaluate gastrointestinal tract. Gastroesophageal Reflux Disease (GERD) is defined as presence of reflux symptoms (heartburn and regurgitation) associated or not with…
- Trial name
- NCT02575287
- Testing
- Optical Enhancement, Optical Enhancement with optical magnification, Optical magnification without Optical enhancement
- Where
- Ecuador
- Volunteers
- 100 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Inflammatory Bowel Diseases, Colorectal Neoplasms
Back-to-back Endoscopy Versus Single-pass Endoscopy and Chromoendoscopy in IBD Surveillance
The current international guidelines for CRC surveillance in IBD recommend as first choice the use of chromoendoscopy, and as an alternative high-definition white light endoscopy (HDWLE) for optimal dysplasia detection, based on…
- Trial name
- HELIOS (NCT04291976)
- Testing
- Back-to-back high-definition white light endoscopy, single-pass high-definition white light endoscopy, chromoendoscopy
- Where
- 4 sites in Netherlands
- Volunteers
- 563 people
- Sponsor
- Radboud University Medical Center
Intestinal Metaplasia, Intestinal Dysplasia
Comparison Between Probe-based Confocal Laser Endomicroscopy, White-light Endoscopy and Virtual Chromoendoscopy
The investigators hypothesis that 1. clinical applicability and overall diagnostic sensitivity and specificity of pCLE for diagnosing gastric preneoplastic and neoplastic lesions is acceptable 2.
- Trial name
- pCLE-GCEP (NCT01398579)
- Testing
- Gastroscopy
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- National University Hospital, Singapore
Colorectal Polyps
Virtual Chromoendoscopy for Distal Polyps
To assess the accuracy of predicting histology with virtual chromoendoscopy for distal colorectal polyps according to the ASGE PIVI statement.
- Trial name
- NCT02217449
- Testing
- Prediction of histology
- Where
- Germany
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School