Clinical trials: Chromoendoscopy
Early Esophageal Squamous Neoplasia
Diagnostic Value of Optical Enhancement Technology in Early Esophageal Squamous Neoplasia
The aims of the present study： 1. To investigate the diagnosing value of optical enhancement technology for early esophageal squamous neoplasia. 2.
- Trial name
- NCT02851264
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Shandong University
Inflammatory Bowel Disease (IBD), Ulcerative Colitis (Disorder)
Virtual Versus Dye-based Chromoendoscopy in Inflammatory Bowel Disease Surveillance Colonoscopy
People with inflammatory bowel disease (IBD), such as ulcerative colitis or Crohn's disease affecting the colon, have a higher risk of developing colon cancer over time.
- Conditions
- Inflammatory Bowel Disease (IBD), Ulcerative Colitis (Disorder), Crohns Disease, Colorectal Neoplasms
- Trial name
- NCT07089771
- Testing
- Virtual Chromoendoscopy, Dye-Based Chromoendoscopy
- Where
- Sweden
- Volunteers
- 480 people
- Sponsor
- Region Stockholm
Colon Adenoma
Can Pan-Colonic Chromoendoscopy (PCC) Improve Adenoma Detection Rate in FIT-Positive-Patients: A Randomized Study
Colonoscopy is the technique of choice for evaluation of patients with positive fecal occult blood (FIT). Identification of polyps and their removal has been shown to decrease colorectal cancer incidence rates and mortality.
- Trial name
- PCC (NCT04512612)
- Testing
- Chromoendoscopy, High definition white light colonoscopy
- Where
- Singapore
- Volunteers
- 250 people
- Sponsor
- Singapore General Hospital
Ulcerative Colitis, Chromoendoscopy
The Clinical Value of Chromoendoscopy as Surveillance Strategy for Dysplasia Detection in Ulcerative Colitis
A recent multicentre randomised controlled trial compared autofluorescence imaging (AFI) with CE for dysplasia detection in colonoscopy surveillance of patients with longstanding UC (FIND-UC).
- Trial name
- NCT03824418
- Testing
- Surveillance colonoscopy with chromoendoscopy
- Where
- Netherlands
- Volunteers
- 210 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Esophageal Squamous Cell Carcinoma
The Efficacy of N-acetylcysteine on Alleviating Symptom Caused by Lugol Chromoendoscopy
Lugol chromoendoscopy is essential in detecting and characterizing squamous cell carcinoma of esophagus. Esophageal irritating symptom has been reported as an common adverse event, which could be alleviated by sodium thiosulfate…
- Trial name
- NCT04764643
- Testing
- N-acetylcysteine solution, sodium thiosulfate solution
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Esophageal Neoplasms
A Diagnostic Study of the Advanced Endoscopy to Detect Early Esophageal Cancer
This descriptive cross sectional study aims to directly compare the diagnostic capability of the probed-based confocal laser endomicroscopy (pCLE) and the magnifying narrow band imaging (M-NBI) in the Lugol's voiding lesions.
- Trial name
- NCT02182804
- Testing
- Olympus, Cellvizio
- Volunteers
- 44 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Squamous Cell Carcinomas of the Head and Neck
Chromoendoscopy to Detect Early Synchronous Second Primary Esophageal Carcinoma
Patients with HNSCC represent a high-risk group for the development of SESCC. Thus, esophagogastrofibroscopy should be performed to detect possible synchronous esophageal carcinomas in these patients.
- Trial name
- HNSCC (NCT01783158)
- Testing
- Esophagoscopy and chromoendoscopy
- Where
- Czechia
- Volunteers
- 132 people
- Sponsor
- University Hospital Ostrava
Superficial Esophageal Neoplasia
Narrow Band Imaging (NBI) Against Lugol for Squamous Esophageal Cancer
This study aimed to compare Narrow Band Imaging (NBI) against Lugol chromoendoscopy for diagnosis of early esophageal cancers among high risk patients.
- Trial name
- NCT02002559
- Volunteers
- 180 people
- Sponsor
- Chinese University of Hong Kong
Celiac Disease
Virtual Chromoendoscopy With Magnification in Coeliac Disease.
High-definition white light endoscopy (HD-WLE) does not usually allow the visualization of duodenal villous patterns and may be inaccurate for assessing coeliac disease (CD).
- Trial name
- NCT05103150
- Testing
- High-definition white light endoscopy (HD-WLE), HD-WLE plus I-Scan optical enhancement (OE) virtual chromoendoscopy with High-definition optical magnification (HD-OM)
- Where
- Ecuador
- Volunteers
- 40 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Colonic Polyps, Adenomatous Polyps
Impact of Indigo Carmine Pump Spraying on the Adenoma Detection Rate
Detection and removal of polyps during colonoscopy is crucial for the prevention of colorectal cancer. Indigo carmine spraying up to the colonic mucosa could probably increase the adenoma detection rate.
- Conditions
- Colonic Polyps, Adenomatous Polyps, Adenoma Detection Rate, Chromoendoscopy
- Trial name
- NCT06596317
- Testing
- Chromoendoscopy, Conventional colonoscopy
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Shandong University
Colon Polyp
Combined Chromoendoscopy and Water Method for Screening Colonoscopy
In a RCT in screening colonoscopy subjects, we will determine if chromoendoscopy using a dilute solution of Indigocarmine (IC) delivered by the water method (study method) will improve adenoma detection rate compared with the…
- Trial name
- NCT01383265
- Testing
- Water method and chromoendoscopy, Water method
- Where
- United States
- Volunteers
- 1,177 people
- Sponsor
- VA Northern California Health Care System
Chromoendoscopy
Virtual Chromoendoscopy With Second Generation NBI (HQ190) vs Chromoendoscopy in Inflammatory Bowel Disease
Study to compare the detection of neoplastic lesions between chromoendoscopy and NBI
- Trial name
- NCT04403997
- Testing
- Chromoendoscopy
- Where
- Spain
- Volunteers
- 175 people
- Sponsor
- Hospital Universitario La Paz
Colorectal Polyp
Prediction of Diminutive/Small Polyp Histology: Didactic vs. Computer-based Training
Bowel cancer is one of the most common cancers and the best method of diagnosing it is through endoscopic examination of the bowel (colonoscopy).
- Trial name
- NCT03843567
- Testing
- Endoscopic characterisation training
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Colonoscopy
Chromoendoscopy in Inflammatory Bowel Disease
Patients with longstanding ulcerative colitis (inflammatory bowel disease, IBD) have increased risk of developing colorectal cancer (CRC) when compared with that of the general population.
- Trial name
- NCT03250780
- Testing
- indigo-carmine 0.2% using a spray catheter, 0.03% using a foot pump
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Gastritis, Helicobacter Pylori Associated Gastritis
New Technology to Differentiate Normal Gastric Mucosa From Helicobacter Pylori Associated Gastritis and Gastric Atrophy
Endoscopy is a tool that has greatly influenced gastroenterological diagnosis. However, conventional endoscopy is limited to detecting lesions on the basis of gross morphological changes and therefore a certainly diagnosis…
- Conditions
- Gastritis, Helicobacter Pylori Associated Gastritis, Atrophic Gastritis
- Trial name
- NCT02597517
- Testing
- Digital chromoendoscopy and magnification
- Where
- Ecuador
- Volunteers
- 72 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Colorectal Adenoma, Colorectal Adenomatous Polyp
Analysis of New Endoscopic Features and Variable Stiffness in Colonoscopy: Prospective Randomised Trial
The aim of the present study is to develop and evaluate a computer-based methods for automated and improved detection and classification of different colorectal lesions, especially polyps.
- Trial name
- ELUFIBLI (NCT03234725)
- Where
- Hungary
- Volunteers
- 1,000 people
- Sponsor
- Bács-Kiskun County Teaching Hospital
Colorectal Cancer, Colorectal Cancer Stage I
Web-based Learning Module on Optical Diagnosis of Early Colorectal Cancer
International guidelines recommend deciding the treatment of colorectal lesions based on the estimated histology by endoscopic optical diagnosis.
- Trial name
- LODIP (NCT05663788)
- Testing
- E-learning module
- Where
- 12 sites in United States, Japan and 2 more
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Inflammatory Bowel Diseases, Dysplasia
Artificial Intelligence and Dysplasia Detection in Inflammatory Bowel Disease (EIIDISIA Study)
Randomized clinical study analyzing the efficacy of colonoscopy assisted by the Computer Aided Detection (CADe) system compared to virtual chromoendoscopy with Narrow Band Imaging (NBI) in the detection of colon dysplasia in…
- Trial name
- NCT06281392
- Testing
- CADe system, NBI
- Where
- Spain
- Volunteers
- 122 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Familial Adenomatous Polyposis
Adenoma Detection Rate:NBI, AFI, Chromoscopic or Standard Endoscopy
The purpose of this study is to establish whether new techniques that may make polyps (adenomas) stand out better from the background help increase the number of polyps visible at sigmoidoscopy (telescope test to look inside…
- Trial name
- NCT00253812
- Testing
- flexible sigmoidoscopy
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- London North West Healthcare NHS Trust
Gastric Tumors
Usefulness of Near-focus With Narrow-band Imaging
Near-focus with narrow-band imaging is a novel technique to improve the quality of images of the irregular mucosal structures and microvessels of gastric neoplasms.
- Trial name
- NCT02661945
- Testing
- Near focus with narrow band imaging
- Where
- 7 sites in South Korea
- Volunteers
- 444 people
- Sponsor
- Kyunghee University Medical Center