Clinical trials: Chronic Aphasia, open to volunteers
Aphasia, Stroke
Effects of Recursive Self-feedback on Speech Production in Aphasia
The goal of this clinical trial is to test the effects of recursive self-feedback procedures on spontaneous speech production in stroke survivors with impaired speech production (aphasia).
- Trial name
- NCT06323629
- Testing
- Adaptive recursive self-feedback procedure, Non-adaptive recursive self-feedback procedure
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of South Florida
Aphasia, Acquired, Chronic Stroke
VR and Scrip Training of PWA, Randomized Controlled Trial
The goal of this RCT is to investigate if computerized script training may promote functional communication and nonverbal cognitive functions of Cantonese-speaking PWA, and whether VR may further magnify the treatment outcomes.
- Trial name
- VRSTPWA (NCT06722092)
- Testing
- VR-based script training, Conventional script training
- Volunteers
- 105 people
- Sponsor
- The Hong Kong Polytechnic University
Non-fluent Aphasia
Combined Intervention Program for Non-fluent Aphasia Based on Neuroplasticity
Sequentially applying Melodic Intonation Therapy (MIT) during the subacute phase, followed by Constraint-Induced Aphasia Therapy (CIAT) during the chronic phase
- Trial name
- CIPAN (NCT07759375)
- Testing
- CIPAN = MIT + CIAT, MIT + MIT, CIAT + CIAT
- Volunteers
- 48 people
- Sponsor
- Universidad de Granada
Aphasia, Acquired, Speech Therapy
Anomia Therapy and Executive Function Training in Chronic Post-stroke Aphasia: Pilot Study of Multidimensional Effects
The goal of this clinical trial is to measure the effects of a speech therapy protocol combining anomia therapy and executive function training on naming and discourse in people with chronic aphasia, and to study the related…
- Trial name
- ATAC2PILOT (NCT06712225)
- Testing
- Anomia therapy: semantic feature analysis and phonological components analysis;, Executive function training: computerized equipment
- Volunteers
- 8 people
- Sponsor
- University Hospital, Montpellier
Aphasia, Chronic Stroke
Transcutaneous Vagus Nerve Stimulation in Aphasia After Stroke
Aphasia is an acquired language disorder. Stroke is the most common cause of aphasia, which affects 30% of stroke survivors. Speech and Language Therapy (SLT) can help people with aphasia but it may not be provided at the…
- Trial name
- TRANSLATE (NCT06403475)
- Testing
- Transcutaneous Vagus Nerve Stimulation, Computer Based Speech and Language Therapy (Step by Step)
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Aphasia, Stroke
Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
The purpose of this study is to assess changes in language abilities of participants with chronic, post-stroke aphasia following an 8-week therapy period combined with brain stimulation.
- Trial name
- NCT04142866
- Testing
- Anodal transcranial direct current stimulation, Speech-Language Therapy (SLT)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- City University of New York
Post-Stroke Chronic Aphasia
Ecological Momentary Intervention for Post-Stroke Anomia
Anomia (i.e., impaired word retrieval) is one of the most common and debilitating deficits experienced by stroke survivors with aphasia, an acquired disorder characterized by impaired language.
- Trial name
- NCT07739875
- Testing
- Semantic Feature Ecological Momentary Intervention
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Northeastern University
Stroke, Aphasia Following Cerebral Infarction
Combined Aphasia and Robot-Assisted Arm Treatment for Chronic Stroke Survivors
The goal of this clinical trial is to learn if a program that combines language and arm treatment can improve language and movement problems in people with chronic stroke.
- Conditions
- Stroke, Aphasia Following Cerebral Infarction, Hemiparesis After Stroke
- Trial name
- CARAT (NCT07000019)
- Testing
- CARAT: combined aphasia and robot-assisted arm therapy, Robot-assisted arm therapy
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- New York Medical College
Aphasia
Effect of Community Choir Singing in People With Chronic Post-stroke Aphasia
The goal of this randomized controled trial is to test the effects of assigning people with chronic post-stroke aphasia to 12 weekly choir sessions, compared to usual care.
- Trial name
- NCT06368323
- Testing
- Choir singing, Usual care
- Where
- 4 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- University of Ottawa
Stroke, Ischemic Stroke
Detecting and Predicting Post-stroke Cognitive Impairment Using the Oxford Cognitive Screen
Cognitive problems are common after a stroke and must be identified early so that rehabilitation can be initiated to improve outcome.
- Conditions
- Stroke, Ischemic Stroke, Hemorrhagic Stroke, Intracerebral, Cognitive Dysfunction
- Trial name
- OCS-PRECISE (NCT07897916)
- Where
- 2 sites in Denmark
- Volunteers
- 180 people
- Sponsor
- University of Copenhagen
Stroke, Aphasia
Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.
62 patients who are one year post stroke and have Aphasia as a result of that stroke will be recruited. Participants will have 4 assessment sessions and 15 treatment sessions.
- Trial name
- AphasiatDCS (NCT04432883)
- Testing
- Active Comparator: Experimental: Active cathodal tDCS + language training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of New Mexico
Ischaemic Stroke, Hemorrhagic Stroke
Exploratory Study on the Potential Cross-System Effects of BCI-FES Hand Therapy on Dysphagia and Aphasia in Chronic Stroke Patients
The goal of this neurorehabilitation explorative study is to investigate how a closed-loop Brain-Computer Interface Functional Electrical Stimulation (BCI-FES) therapy, used within the intended purpose for hand rehabilitation…
- Trial name
- c-STEPS (NCT06940635)
- Testing
- closed-loop BCI-FES device
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- VASCage GmbH
Aphasia, Apraxia of Speech
Changes in Neuroplasticity Following Intensive Rehabilitation of Aphasia and/or Apraxia of Speech
The present study aims to investigate the short- and long-term effects of two weeks of intensive speech-language pathology intervention with additional physiotherapy, on aphasia and apraxia of speech (AOS) and their neural…
- Conditions
- Aphasia, Apraxia of Speech, Dysarthria
- Trial name
- NCT04604444
- Testing
- Multimodal Intensive Rehabilitation of Aphasia and Apraxia of Speech
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Aphasia, Stroke
Effect of Anomia Rehabilitation Combined With Metacognitive Training in Patients With Chronic Vascular Aphasia
The postulate of this study is that rehabilitation combining linguistic and metacognitive training will result in a significant improvement in language performance correlated with changes in functional cerebral connectivity…
- Trial name
- METALEX (NCT06930131)
- Testing
- Semantic rehabilitation
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Toulouse