Clinical trials: Chronic Brain Injury
Chronic Subdural Hematoma
Middle Meningeal Artery Embolization With Liquid Embolic Agent for Treatment of Chronic Subdural Hematoma
The study evaluates the clinical and imaging outcome of middle meningeal artery (MMA) embolization with liquid embolic agent for treatment of chronic subdural hematoma (CSDH)
- Trial name
- NCT04574843
- Testing
- Embolization of MMA
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Mashhad University of Medical Sciences
Chronic Subdural Hematoma
Frontal vs Parietal Eminence Drainage for Chronic Subdural Hematoma
This clinical trial aims to find out whether the puncture site used during minimally invasive surgery with twist-drill puncture and closed-system drainage affects the treatment of chronic subdural hematoma (cSDH).
- Trial name
- NCT07731620
- Testing
- Frontal-region puncture drainage, Parietal Eminence region puncture drainage
- Where
- 3 sites in China
- Volunteers
- 440 people
- Sponsor
- The Second Hospital of Anhui Medical University
Cerebral Palsy, Upper Extremity Paresis
Virtual Reality Mediated Upper Extremity rehabilitationPatients With Cerebral Palsy
Cerebral palsy (CP) refers to a group of permanent disorders that occur in the brain of the fetus or infant, which are non-progressive, cause movement and posture disorder along with activity limitation.
- Trial name
- NCT04529343
- Testing
- Virtual reality mediated upper extremity rehabilitation, Classical exercise therapy for upper extremities
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Cerebral Palsy, Father-Child Relations
Life Satisfaction of Fathers of Children With Cerebral Palsy
The purpose of this study is to examine the determinants of life satisfaction among fathers of children diagnosed with Cerebral Palsy.
- Conditions
- Cerebral Palsy, Father-Child Relations, Life Satisfaction
- Trial name
- NCT06437340
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Cerebral Palsy
Which Taping Technique is More Effective on Balance Skills in Children With Mildly Affected Cerebral Palsy?
"Our study aims to determine which of ankle correction, quadriceps facilitation, and gluteus maximus facilitation taping provides a better immediate effect on balance skills in children with mildly affected cerebral palsy.
- Trial name
- NCT06231108
- Testing
- Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Abant Izzet Baysal University
Cerebral Palsy Infantile
Single-Button Mobility Platform's Effect on Reaction Time and Keystroke Accuracy in Children with Cerebral Palsy
The goal of this clinical trial is to determine whether the use of a mobility platform can improve response time in children with cerebral palsy.
- Trial name
- NCT06616610
- Testing
- Intervention with the Mobility Platform, Intervention with Traditional Therapy
- Where
- Spain
- Volunteers
- 4 people
- Sponsor
- University of Seville
Cerebral Palsy, Multiple Sclerosis
The EXOPULSE Study - a Database for Routine Follow-up of Clinical Outcomes
The objective is to explore the potential short and long-term impact of the EXOPULSE Mollii Suit and EXOPULSE Suit on subjects with CP, MS, stroke, fibromyalgia or other neurologic disorders which may cause such types of…
- Conditions
- Cerebral Palsy, Multiple Sclerosis, Stroke, Neurologic Disorder
- Trial name
- EXOREG (NCT05901259)
- Testing
- EXOPULSE Mollii Suit and EXOPULSE Suit
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Otto Bock Healthcare Products GmbH
Cerebral Palsy, Infant Development
Neuroimaging of Babies During Natural Sleep to Assess Typical Development and Cerebral Palsy
Background: Early diagnosis of cerebral palsy (CP) is crucial, enabling intervention when neuroplasticity is at its highest. Magnetic resonance imaging (MRI) plays a vital role in CP diagnosis.
- Conditions
- Cerebral Palsy, Infant Development, Development, Infant
- Trial name
- NIBS-CP (NCT06396520)
- Testing
- No intervention, observational
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Danish Research Centre for Magnetic Resonance
Trauma, Nervous System, Brain Trauma
Characterization of the Sleep-Wake Cycle in Traumatic Brain Injury Patients with a Disorder of Consciousness
Each year in France, 160,000 peoples suffer from a mild or severe traumatic brain injury (TBI). Sleep plays a crucial role in the process of brain plasticity, which is essential for neurological and cognitive recovery.
- Trial name
- SLEEPDOC (NCT06766513)
- Testing
- Actimetry, Subjective assessments, questionnaire
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Cerebral Palsy
Effects of Robotic Gait, Hydrotherapy, and Conventional Physiotherapy in Spastic Hemiparetic CP
This study aims to evaluate the effects of three different physiotherapy approaches-robot-assisted gait training, hydrotherapy, and conventional physiotherapy-on muscle strength, balance, functional mobility, and psychological…
- Trial name
- NCT07031609
- Testing
- Robot-assisted gait training using Lokomat, Hydrotherapy, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul Arel University
Mild to Moderate Traumatic Brain Injury
PoNS Clinical Experience Program (TBI)
Brief Summary: Prospective, cohort, open-label study. The cohort consists of people who have a chronic balance dysfunction due to a mild to moderate traumatic brain injury (TBI).
- Trial name
- NCT03732755
- Testing
- PoNS Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Helius Medical Inc
Cerebral Palsy, Growth
Predictive Models of Weight and Height for the Evaluation of the Growth of Children and Adolescents With Cerebral Palsy
Cerebral palsy (CP) is the most frequent disability in children. The vast majority of these patients are malnourished. In this population, there are practical difficulties to perform a nutritional and growth assessment which…
- Conditions
- Cerebral Palsy, Growth, Child
- Trial name
- NCT03303755
- Where
- Argentina
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Cerebral Palsy, Spina Bifida
A Peer E-mentoring Intervention to Improve Employment
Despite the strong business case of hiring people with disabilities, a significant proportion of youth with disabilities leave high school and neither work nor continue their education and are unprepared to meet the demands of a…
- Conditions
- Cerebral Palsy, Spina Bifida, Juvenile Arthritis, Spinal Cord Injury
- Trial name
- NCT02522507
- Testing
- Empowering youth towards employment
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Cerebral Palsy
Effect of Transcutaneous Electrical Nerve Stimulation (TENS) on Spasticity in Adult Patients With Spastic Cerebral Palsy
Background: Cerebral palsy (CP) is a neurodevelopmental disorder caused by damage of the developing brain and marked by impairments such as increased muscle tone.
- Trial name
- NCT05352607
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Conventional physiotherapy treatment
- Where
- Saudi Arabia
- Volunteers
- 23 people
- Sponsor
- Reem Alharthi
Diplegic Cerebral Palsy
Effect of Q Angle and BMI on Dynamic Balance in Spastic Diplegic Children
The study aims to correlating q angel and BMI to dynamic balance in the diplegic children
- Trial name
- NCT07725627
- Volunteers
- 72 people
- Sponsor
- Cairo University
Cerebral Palsy
Magnesium Therapy in Children With Cerebral Palsy
This study is considered a pilot exploratory study. Intervention, prospective, double-armed, randomized, placebo-control clinical trial.
- Trial name
- NCT02510222
- Testing
- Oral magnesium sulfate
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Chronic Subdural Hematoma
YL-1 Needle Puncture vs BHC With Postoperative Exhaustive Drainage for CSDH
A prospective multicenter cohort study was designed to compare the differences in complications with YL-1 Needle Puncture versus Bulr-hole Craniotomy (BHC) with postoperative Exhaustive Drainage strategy for patients with Chronic…
- Trial name
- NEBULA (NCT06072053)
- Testing
- Burr Hole Craniostomy and Postoperative Exhaustive Drainage Strategy, YL-1 puncture needle and Postoperative Exhaustive Drainage Strategy
- Where
- China
- Volunteers
- 460 people
- Sponsor
- Beijing Tiantan Hospital
Epilepsy, Seizure Disorder
Epilepsy Learning Healthcare System (ELHS)
The Epilepsy Learning Health System (ELHS) is a quality improvement and research network to improve outcomes for people with epilepsy.
- Conditions
- Epilepsy, Seizure Disorder, Neurologic Disorder, Rare Diseases
- Trial name
- ELHS (NCT06265103)
- Testing
- Clinical care and quality improvement
- Where
- 13 sites in United States
- Volunteers
- 100,000 people
- Sponsor
- Epilepsy Foundation of America
Cerebral Palsy
Extending taVNS Paired With Infant CIMT Into a Home-Based Setting
Newborns who are born premature or suffer brain injury at birth are at risk for motor problems that may cause weakness in reaching and grasping on one side of the body.
- Trial name
- NCT05857527
- Testing
- Custom EMG triggered Soterix taVNS stimulation with CIMT therapy in lab, Custom EMG triggered Soterix taVNS stimulation with CIMT therapy in home
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Medical University of South Carolina
Achilles Tendon Surgery, Cerebral Palsy
Gastrocsoleus Lengthening in Cerebral Palsy
The goal of this study is to compare passive ankle and knee range of motion (ROM) development after surgery to the gastrocsoleus complex, in children with cerebral palsy (CP).
- Trial name
- NCT05783739
- Volunteers
- 186 people
- Sponsor
- Region Skane