Clinical trials: Chronic Condition
Pain, Chronic, Back Pain
Back Pain and Arthroplasty in Orthopedists
The relationship between arthroplasty and low back pain in orthopedists will be evaluated.
- Trial name
- NCT04505332
- Testing
- arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Uludag University
Chronic Obstructive Pulmonary Disease
Comparison of Repetitive Magnetic Stimulation and Exercise on Quadriceps Function in COPD
Background Chronic Obstructive Pulmonary Disease (COPD) patients develop leg weakness and a reduced walking capacity, due to reduced leg muscle oxygen-utilising capacity (OUC).
- Trial name
- NCT00737698
- Testing
- Exercise, Repetitive magnetic stimulation
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Temporomandibular Disorders, Craniomandibular Disorders
The Influence of a Stabilization Splint on the Body Posture
The study was designed to investigate a possible influence of an occlusal stabilization splint on the body posture in TMD cases and controls.
- Conditions
- Temporomandibular Disorders, Craniomandibular Disorders, Arthromyalgia, Chronic Disease
- Trial name
- NCT00154128
- Testing
- occlusal appliance
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Emphysema, Chronic Obstructive Pulmonary Disease
Emphysema Research Registry and Biosample Repository
The Comprehensive Lung Center (CLC) at the University of Pittsburgh Medical Center (UPMC Health System) provides patients with any type of breathing or lung disorder a full range of diagnostic and therapeutic services.
- Conditions
- Emphysema, Chronic Obstructive Pulmonary Disease, Chronic Bronchitis
- Trial name
- NCT00307281
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Back Pain, Low, Back Pain
Quality Improvement re: Choosing Wisely Back Pain Measures
As
- Conditions
- Back Pain, Low, Back Pain, Back Pain Lower Back Chronic
- Trial name
- SCV LBP (NCT05413070)
- Testing
- Multimodal approach to QI for Low-Value Care
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Vitamin D Deficiency
Vitamin D and Muscle Strength and Surface (Electromyography) EMG
Vitamin D deficiency is widely prevalent in India. Serum 25(OH)D levels are <20 ng /ml in up to 90% of them. Recently, in a randomized control trial, investigators have shown that dual cholecalciferol and calcium supplementation…
- Trial name
- NCT01190683
- Testing
- Cholecalciferol, Calcium Carbonate, cholecalciferol and calcium carbonate
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Indian Council of Medical Research
Chronic Venous Insufficiency
Respiratory and Physical Functions in Individuals With Chronic Venous Insufficiency
In the literature, it is still unclear whether individuals with chronic venous insufficiency are affected by edema, pain, respiratory muscle strength, respiratory functions, functional capacity, lower extremity strength and…
- Trial name
- NCT06196541
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Chronic Kidney Disease, Renal Osteodystrophy
Serum Sclerostin Levels, Cardiovascular Parameters and Carpal Tunnel Syndrome in Maintenance Hemodialysis Patients
Sclerostin, the product of the SOST gene, located on chromosome 17, locus q11.2 in humans, was originally believed to be a non-classical Bone morphogenetic protein (BMP) antagonist.Sclerostin was recently identified as a…
- Conditions
- Chronic Kidney Disease, Renal Osteodystrophy, Left Ventricular Hypertrophy
- Trial name
- NCT01382966
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- RFM Renal Treatment Services
Hepatocellular Carcinoma
Epigenetic Changes in Hepatocellular Carcinoma Developed After Direct Acting Antiviral Therapy for Chronic Hepatitis C
Hepatocellular carcinoma (HCC) is the most common type of liver cancer, its survival rate ranks only second to lung cancer and it is a severe threat to human health. In Egypt, HCC constitutes a significant public health problem.
- Trial name
- NCT04220151
- Testing
- DNA methylation
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chronic Diseases in Children
NICE - Nutritional Impact on Immunological Maturation During Childhood in Relation to the Environment
Role of the exposome on allergy, caries, and neurophysiological development in childhood.
- Trial name
- NICE (NCT05809479)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 1,950 people, healthy volunteers welcome
- Sponsor
- Umeå University
Hypoxia, Altitude, Blood Flow Restriction
Effects of Low-Intensity Blood Flow Restriction Training in Normoxia and Hypoxia Conditions
One approach to significantly reducing resistance training intensity while maintaining effectiveness in muscle mass and strength development involves conducting training sessions under hypoxic conditions.
- Conditions
- Hypoxia, Altitude, Blood Flow Restriction, Resistance Training
- Trial name
- NCT06171841
- Testing
- low-intensity resistance training, high-intensity resistance training, low-intensity resistance training combined with blood flow restriction
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Chronic Hepatitis C
A Study to Evaluate the Effect of ACH-3102 and Simeprevir on AL-335 Pharmacokinetics in Healthy Volunteers
This is an open-label, two-group, fixed-sequence study to evaluate the effect of ACH-3102 and Simeprevir on AL-335 pharmacokinetics in healthy volunteers.
- Trial name
- NCT02512562
- Testing
- AL-335, ACH-3102, Simeprevir
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Alios Biopharma Inc.
Chronic Granulomatous Disease (CGD), X-Linked Severe Combined Immune Deficiency (XSCID)
Evaluation of Patients With Immune Function Abnormalities
This study will evaluate patients with abnormal immune function that results in recurrent or unusual infections or chronic inflammation.
- Conditions
- Chronic Granulomatous Disease (CGD), X-Linked Severe Combined Immune Deficiency (XSCID), Leukocyte Adhesion Deficiency 1 (LAD), Graft Versus Host Disease (cGvHD)
- Trial name
- NCT00128973
- Where
- United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pulmonary Fibrosis
Supplemental Oxygen in Pulmonary Fibrosis
To enhance understanding of supplemental oxygen-its utility in and adoption by patients with pulmonary fibrosis-by examining how patients perceive it and by determining how perceptions and patient-centered outcome measures change…
- Trial name
- NCT01961362
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
Chronic Pain
Multiple Dose Study of Safety and Pharmacokinetics of MEDI0618 in Healthy Volunteers
This is a single centre, randomised, double-blind, placebo-controlled, multiple ascending dose study of MEDI0618 in healthy male and female volunteers.
- Trial name
- NCT05714254
- Testing
- MEDI0618
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Sinonasal Disorder, Chronic Rhinosinusitis (Diagnosis)
The Sinonasal Microbiome
Chronic rhinosinusitis is an inflammatory disease of the sinonasal mucosa with significant impact and limited treatment options.
- Trial name
- NCT06822725
- Testing
- Control Group, Chronic rhinosinusitis (CRS) with and without Nasal Polyposis
- Where
- United States
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Liver Cirrhosis, Liver Insufficiency
Hepatocyte Matrix Implant Study Indonesia
This clinical investigation of the hepatocyte matrix implant is an evaluation blinded non-randomized and monocentric pilot study of Phase I, which is conducted as a therapeutic investigation.
- Conditions
- Liver Cirrhosis, Liver Insufficiency, Chronic Liver Disease
- Trial name
- HMIIndo (NCT01335568)
- Testing
- Hepatocyte Matrix Implant
- Where
- Indonesia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Baermed
Atheroscleroses, Geriatric
Development and Validation of a Scale of Propensity for Change in Chronic Disease Prevention
Modifiable risk factors are estimated to account for 70% of cardiovascular diseases, 40% of Alzheimer's-type dementias, and 50% of type 2 diabetes cases.
- Trial name
- ProChange (NCT07765797)
- Testing
- Scale development phase, Beta testing phase, Validation phase
- Where
- France
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Quality of Life, Pain
QOL, ADL and Pain Before and After Intervention With N3 From Krill With D3.
The aim of this project is investigation of patients' with chronic pain self-rated quality of life, ADL function and level of pain before and after 3 months of intervention with N-3 fatty acids from krill in combination with…
- Trial name
- NCT02008760
- Testing
- Omega Krill with D3
- Where
- Denmark
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Hospitalet Valdemar
Cerebral Palsy
Brain Control of Movements in Cerebral Palsy
This study will examine how the brain controls movements in patients with certain types of cerebral palsy. In healthy people, one side of the body usually controls movements on the other side of the body.
- Trial name
- NCT00076596
- Where
- 2 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)