Clinical trials: Chronic Conditions
Overweight
Chronic Effects of Natural and Interesterified Fats Margarine on Insulin Sensitivity and Selected Markers of Cardiovascular Diseases (CVD)
The investigators hypothesized that there will be a significant difference between the effects of trans-free palm-, interesterified palm- and interesterified soybean oil blend on cardiovascular disease, inflammation, insulin…
- Trial name
- NCT02192047
- Testing
- Palm Olein, IE Palm olein, IE soybean oil-based
- Where
- Malaysia
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
COPD
Loop Band Validation Study
The main purpose of this study is to assess the accuracy of a non-invasive wearable technology in the form of a wristband.
- Trial name
- NCT03240926
- Testing
- Loop Band
- Where
- United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Spry Health
Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease
Social Work Intervention Focused on Transitions
In response to Program Announcement (PA)-09-164, "NIH Exploratory/Developmental Research Grant Program (R21) a randomized pilot study testing the efficacy of SWIFT: Social Work Intervention Focused on Transitions among at-risk…
- Conditions
- Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease, Diabetes, Hypertension
- Trial name
- SWIFT (NCT02232126)
- Testing
- SWIFT home intervention
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Shoulder Pain Chronic, Core Strength
Investigation of Core Muscle Strength in Patients With Unilateral Rotator Cuff Injury
Located in the middle of the kinetic chain system, the core muscles are the regions where forces are generated and transferred to the extremities of the body.
- Trial name
- NCT06689826
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Ahi Evran University Education and Research Hospital
Pain, Chronic, Pain, Joint
Subjective Observational Study of Patients Using Transdermal Cream Medication And/Or Transdermal Patches With Or Without Oral Non-Narcotic Medications
purpose of this study is to evaluate the level of pain perceived by patients using a transdermal cream and/or transdermal patch with or without an oral medication as a pain management solution.
- Conditions
- Pain, Chronic, Pain, Joint, Pain Syndrome
- Trial name
- NCT03768011
- Testing
- transdermal cream and or patch
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Data Collection Analysis Business Management
Lower Back Pain, Lumbar Spondylosis
Using Music During Lumbar Medial Branch Block Procedure
The purpose of this study is to determine if music therapy during interventional lumbar medial branch blocks for chronic lower back pain will lower pain scores and anxiety levels, while increasing patient desire for repeat…
- Trial name
- NCT04091607
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Chronic Kidney Disease
Study to Collect Samples for MIST Analysis of Zibotentan and Bioavailability of Zibotentan and Dapagliflozin in Heatlhy Participants
The study will have 2 independent parts: Part 1 of the study is intended to collect samples for Metabolites in Safety Testing (MIST) analysis after administration of multiple doses of zibotentan.
- Trial name
- NCT04991571
- Testing
- Zibotentan (Treatment A), Dapagliflozin (Treatment A), Zibotentan/Dapagliflozin - Formulation 1 (Treatment B)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Chronic Renal Failure
Clinical Study to Compare the Pharmacokinetics and Safety of D113 With CKD-349 in Healthy Volunteers
This study is a randomized, open-label, single dosing, 3-treatment, 6-sequence, 3-period, crossover-design study to compare the pharmacokinetics and safety of D113 with CKD-349 in healthy volunteers.
- Trial name
- NCT04952506
- Testing
- CKD-349 F1 Tab., CKD-349 F2 Tab., D113 Tab.
- Where
- South Korea
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Chronic Obstructive Pulmonary Disease (COPD)
Artificial Intelligence-Based Motion Analysis for Early Detection of COPD
This study aims to develop a non-invasive and contact-free diagnostic system that uses artificial intelligence (AI) to detect Chronic Obstructive Pulmonary Disease (COPD) by analyzing walking patterns.
- Trial name
- NCT07010211
- Testing
- Gait Video Recording and Analysis
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Burcin Celik
Healthy Volunteer
Evaluating the Safety, Tolerability, and Pharmacokinetics of BIIB095 in Healthy Participants
The primary objective of the study is to evaluate the safety and tolerability of single- and multiple-ascending oral doses of BIIB095 in healthy participants.
- Trial name
- NCT03454126
- Testing
- BIIB095
- Where
- 2 sites in United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Biogen
Vitamin D Deficiency, Hypocalcemia
Effect of Vitamin D Supplement on Disease Activity in SLE
To study the effect of vitamin D supplementation on disease activity of SLE ( SLEDAI-2K ) and IL-6 level
- Conditions
- Vitamin D Deficiency, Hypocalcemia, Hyperparathyroidism, Systemic Lupus Erythematosus (Disorder)
- Trial name
- NCT05260255
- Testing
- vitamin D2 ( calciferol )
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Kidney Disease, Chronic
Diuretic Testing in Chronic Kidney Disease
The goal of this clinical trial is to predict the progression of chronic kidney disease by diuretic testing in patients with chronic kidney disease.
- Trial name
- U-TUBE 2 (NCT06841692)
- Testing
- Diuretic Testing
- Where
- Netherlands
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Chronic Disease
Promoting Physical Activity in Churchgoing Latinas
The low prevalence of moderate-to-vigorous physical activity (MVPA) among adult Latinas likely contributes to the high rates of cancer and other chronic diseases in this population.
- Trial name
- NCT01776632
- Testing
- Physical activity, Cancer screening
- Where
- United States
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Acute Diverticulitis
Prospective and Multicentre Study on Clinical-biological Factors Predictive of Chronic Colon DIverticulitis
MAIN OBJECTIVE: Description of predicted markers of acute diverticulitis crisis, using bivariate and multivariate analyses. Analysis of acute diverticulitis predictor swings.
- Trial name
- DICRO (NCT04407793)
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sebastiano Biondo
Chronic Kidney Diseases
Propolis Effects in Patients With Chronic Kidney Disease
The aim of this study is to determine the impact of Propolis on proteinuria reduction and protection of the glomerular filtration rate in chronic renal failure patients.
- Trial name
- NCT02766036
- Testing
- Propolis
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Care Transitions
Improving Care Transitions for Medicaid Insured Individuals With Co-occurring Serious Mental Illness
This study aims to evaluate the THRIVE clinical pathway at HUP, focusing on supporting Medicaid-insured individuals, including those with serious mental illness, following hospitalization.
- Trial name
- THRIVE-SMI (NCT06203509)
- Testing
- Thrive Intervention
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Traumatic and/or Non-traumatic Brain Injury
Assessing Special Features of Impaired Gait After Acquired Brain Injury With an Instrumented Treadmill
Hemiparetic gait following acquired brain injury (ABI) is grossly characterized by decreased speed of walking, increased stance time on the unaffected side, and decreased stance time on the affected side.These abnormalities are…
- Trial name
- NCT01413321
- Where
- Israel
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Anal Fissure, Microbial Colonization
Microbiota in Chronic Anal Fissure and Its Association With Prognosis
In this study, we will try to answer the following questions: 1. What are the salient features of the microbiota in chronic anal fissure? 2. Are these features associated with prognosis and response to therapy? 3.
- Trial name
- NCT05405634
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lasse Krogsbøll
Chronic Obstructive Pulmonary Disease Mild, Chronic Obstructive Pulmonary Disease Moderate
Effect Of Ketamine Infusion In Patients With COPD Applied One Lung Ventilation
Chronic obstructive pulmonary disease (COPD) patients often undergo thoracic surgery due to lung cancer and emphysematous changes.
- Conditions
- Chronic Obstructive Pulmonary Disease Mild, Chronic Obstructive Pulmonary Disease Moderate, Chronic Obstructive Pulmonary Disease Severe, Lungcancer
- Trial name
- NCT02962999
- Testing
- Ketamine, Saline
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Treatment Free Remission, Chronic Myeloid Leukemia
Italian Treatment Free Remission Registry
The investigator propose an extension of the previous National, multicentric study, promoting an observational registry, both retrospective and prospective, in order to expand and further characterize the series of Italian…
- Trial name
- NCT04769947
- Where
- Italy
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
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