Clinical trials: Chronic Conditions
Chronic Disease, Asthma
Feasibility of Ripple Health Smart Pill Caps in Clinical Settings
The purpose of this research is to determine whether Ripple Health Smart Medicine Bottle Caps can allow for better interface medication administration than traditional pill bottles.
- Trial name
- NCT05192928
- Testing
- Ripple Health Smart Pill Cap
- Where
- 4 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Manan Shukla
Chronic Kidney Diseases
A Mass Balance Study of [14C]HRS-1780 in Healthy Adult Male Subjects
The study aims to evaluate the pharmacokinetics, mass balance recovery, metabolite profile and metabolite identification of [14C]HRS-1780 following an oral single dose in healthy adult male participants.
- Trial name
- NCT07557407
- Testing
- [14C]HRS-1780
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
Renal Insufficiency, Chronic, Cardiac Catheterization
Short-term Use of Dapagliflozin to Protect Kidney Function in CKD Patients
This study aim to investigate the protected effects of short-term use of dapagliflozin (administered within 3 days after procedure) in CKD patients after coronary angiography or percutaneous coronary intervention, as well as…
- Conditions
- Renal Insufficiency, Chronic, Cardiac Catheterization, Percutaneous Coronary Intervention
- Trial name
- NCT05225077
- Testing
- Dapagliflozin 10 MG [Farxiga]
- Where
- South Korea
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Dong-A University
Insomnia, Sleep Disorder
Efficacy and Safety Study of Propofol Infusion for Refractory Chronic Primary Insomnia
Insomnia is a widespread condition in which approximately one-third of adults in the United States are symptomatic with 6% of the population meeting the diagnostic criteria for insomnia.
- Conditions
- Insomnia, Sleep Disorder, Dyssomnia
- Trial name
- NCT02043977
- Testing
- propofol injectable emulsion
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Life Extension Foundation Inc.
Chronic Kidney Disease
Exploring the Effects of Exercise Combined With BFRT on Healthy and Patients With CKD
Investigate the effects of exercise training on the cardiopulmonary function and exercise capacity in healthy and CKD patients
- Trial name
- NCT07288905
- Testing
- Aerobic exercise, Blood flow restriction, Resistance exercise
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Atopic Dermatitis, Atopic Dermatitis Eczema
Bioavailability and Tolerability of Fexofenadine Hydrochloride Topical Lotion 1%
The investigational lotion is envisaged as an short- and long term "Ease \& Prevent" monotherapy for adults and children with mild to moderate eczema.
- Conditions
- Atopic Dermatitis, Atopic Dermatitis Eczema, Atopic Rash, Rash
- Trial name
- ATOFEX-1 (NCT05461456)
- Testing
- Fexofenadine Hydrochloride Topical Lotion 1% (OP2101)
- Where
- Bangladesh
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- OrchestratePharma GmbH
Sleep Deprivation, Hippocampal Atrophy
Chronic Sleep Deprivation and Changes in Cortical and Hippocampal Volume
Sleep is a physiological state that is essential for human performance, including academic, occupational, interpersonal, and psychological aspects.
- Conditions
- Sleep Deprivation, Hippocampal Atrophy, Cortical Irregularity
- Trial name
- NCT06260280
- Testing
- Cerebral Nuclear Magnetic Resonance
- Where
- Mexico
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Chronic Pain
Dronabinol Opioid Sparing Evaluation (DOSE) Trial
This study will be a 12-week, open-label trial that is designed to evaluate the Opioid-Sparing effect of Dronabinol at ranging doses when coadministered with the opioid analgesics that are currently being prescribed to patients…
- Trial name
- NCT03766269
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Daisy Pharma Opioid Venture, LLC
Group B Streptococcus
Safety and Immunogenicity of a Group B Streptococcus Vaccine in Healthy Women
This study will evaluate the safety and immunogenicity of a Group B Streptococcus vaccine.
- Trial name
- NCT01150123
- Testing
- Group B streptococcus (GBS) vaccine- low dose, Group B streptococcus (GBS) vaccine- High dose
- Where
- Belgium
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Cancer, Chronic Obstructive Pulmonary Disease
Does Continuous Vital Sign Monitoring Increase Investigations and Interventions in Complication-free Patients?
This aim of this study is to investigate whether active alerts during CVSM result in an increased number of diagnostic tests and treatments in complication free patients, hypothesizing that more interventions are performed in the…
- Conditions
- Cancer, Chronic Obstructive Pulmonary Disease, Surgery-Complications
- Trial name
- WARD-OT (NCT06361862)
- Testing
- Active alarms from WARD software
- Where
- Denmark
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Non-Small Cell Lung Cancer, Chronic Obstructive Pulmonary Disease
Detection of Circulating Endothelial Progenitors Cells (EPCs) in Non-small Cell Lung Cancer (NSCLC)
Bone-marrow-derived progenitor cells (EPCS) play an important role in neovascularization and tumor growth. In lung cancer, angiogenesis is an important event in mechanisms of tumor proliferation and metastasis.
- Trial name
- CBNPC:PCE (NCT00826683)
- Testing
- Enumeration of endothelial cell progenitor in peripheral blood by flow cytometry, Endothelial cell progenitor characterization by primary cell cultures
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Quality of Life, Pain
QOL, ADL and Pain Before and After Intervention With N3 From Krill With D3.
The aim of this project is investigation of patients' with chronic pain self-rated quality of life, ADL function and level of pain before and after 3 months of intervention with N-3 fatty acids from krill in combination with…
- Trial name
- NCT02008760
- Testing
- Omega Krill with D3
- Where
- Denmark
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Hospitalet Valdemar
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Bioequivalence Study of Budesonide/Formoterol Inhalation Powder in Healthy Participants
The goal of this study is to learn if a new formulation of Budesonide/Formoterol Inhalation Powder (160μg/4.5μg), manufactured by Shanghai New Huanghe Pharmaceutical Co., Ltd., works the same as the already approved reference…
- Trial name
- BF-BE (NCT07804303)
- Testing
- Budesonide and Formoterol Fumarate Powder for Inhalation (II) (Test), Budesonide and Formoterol Fumarate Powder for Inhalation (II) (Reference)
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai Xin Huanghe Pharmaceutical Co., Ltd.
Chronic Diseases
Evaluating Community Health Centers' Adoption of a New Global Capitation Payment
The investigators are conducting a prospective analysis of the Alternative Payment Methodology (APM) demonstration project sites. The investigators' goal is to conduct a cross project analysis of findings.
- Trial name
- eCHANGE (NCT02637869)
- Testing
- Alternative Payment Model
- Volunteers
- 400,000 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Chronic Pain, Musculoskeletal Pain
PEACE: Comparing Chronic Pain Treatment Options
The purpose of this study is to compare two types of acupuncture with usual care on treating chronic pain. This study has three groups. Two groups will received acupuncture.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Fibromyalgia, Pain Management
- Trial name
- PEACE (NCT02979574)
- Testing
- Electro-Acupuncture (EA), Battle Field Acupuncture (BFA), Wait List Control (WLC)
- Where
- 7 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Chronic Obstructive Pulmonary Disease
The Respiratory Physiology Variation of COPD Patients in Inspiratory Muscle Training
Background：Respiratory muscle weakness is observed in chronic obstructive pulmonary disease(COPD) patients and contributes to hypercapnia, dyspnoea, nocturnal oxygen desaturation and reduced walking distance.During exercise it…
- Trial name
- NCT02278523
- Testing
- Threshold IMT®
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Renal Insufficiency, End Stage Renal Disease
A Study of Tirzepatide (LY3298176) in Participants With Impaired Kidney Function
The purpose of this study is to assess how fast tirzepatide gets into the blood stream and how long it takes the body to remove it in participants with impaired kidney function compared to healthy participants.
- Trial name
- NCT03482024
- Testing
- Tirzepatide
- Where
- 4 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Low Back Pain, Inflammation
Acute Effects of High Intensity Training on Pain Processing and Inflammation in Chronic Low Back Pain.
A multitude of exercise therapy modalities are effective in improving daily physical function and relieving pain in various forms of chronic musculoskeletal pain (CMP) such as chronic neck pain, osteoarthritis, fibromyalgia, and…
- Trial name
- NCT04902196
- Testing
- high intensity cardiorespiratory exercise protocol, moderate intensity cardiorespiratory exercise protocol
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Spinal Cord Injuries, Obesity
Building an Evidence Base for Weight Loss Strategies Among Those With Chronic SCI-The GLB-SCI+
This study's overarching aim is to follow a systematic approach that incorporates community-based participatory research (CBPR) to develop a multi-component weight loss intervention that may yield significant effects for a…
- Conditions
- Spinal Cord Injuries, Obesity, Weight Loss, Diet Modification
- Trial name
- GLB-SCI+ (NCT03874988)
- Testing
- Portion-Controlled Meals, Enhanced Self-Monitoring, GLB-SCI
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
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