Clinical trials: Chronic Conditions
Disorders of Consciousness
Beneficial Effects of Preference on Behavior in DOC Patients (COGNICOMA)
Preferred music improves cognitive function in patients with disorders of consciousness (DOC). However, it is still unknown whether it is a general effect of music (because of its acoustic features) or an autobiographical effect…
- Trial name
- COGNICOMA (NCT02759068)
- Testing
- sounds and odors
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Ear Noise, Tinnitus, Noise Induced
Multimodal Therapy for Somatosensory Tinnitus
Tinnitus (ringing or buzzing in the ears) affects approximately 10-15% of the adult population and significantly reduces quality of life in many patients.
- Conditions
- Ear Noise, Tinnitus, Noise Induced, Tinnitus, Subjective, Headache Other
- Trial name
- SOMATIN (NCT07468318)
- Testing
- Multimodal physiotherapy for TMJ and Cervical spine, Combined Exercise Program (Aerobic + Resistance + Breathing), Tinnitus-Specific Psychological Support
- Where
- Czechia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Chronic Obstructive Pulmonary Disease
Effects Of of Pursed Lip Breathing and Coordinated Breathing in Adult Patients With COPD
COPD is the chronic lung condition characterized by the damage and enlargement of the air sacs in the lungs, leading to breathing difficulties. A blockage may develop, which traps air inside your lungs.
- Trial name
- NCT06459843
- Testing
- pursed lip breathing techniques, coordinated breathing technique
- Where
- Pakistan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Chronic Pain
Chronic Pain OneSheet Clinical Trial
The purpose of the study is to determine whether and how having access to the Chronic Pain OneSheet clinical decision support tool in Epic affects the ordering, prescribing, goal-setting, risk monitoring, and outcome measuring…
- Trial name
- NCT04295135
- Testing
- Chronic Pain OneSheet
- Where
- 2 sites in United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Indiana University
Paraplegia
High-intensity Interval Training for Cardiometabolic Health in Persons With Spinal Cord Injury
Persons with chronic paraplegia at an increased risk of developing cardiovascular disease and type-2 diabetes compared to the able-bodied population.
- Trial name
- NCT04397250
- Testing
- High-intensity interval training
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Bath
Cardiovascular Disease, Asthma
Effectiveness of Pollution Monitoring in Clinical Exercise Rehabilitation
The primary objective of EPIC-AIR is to evaluate the feasibility and potential effectiveness of integrating real-time air pollution monitoring into cardiac rehabilitation (CR) and pulmonary rehabilitation (PR) programmes via an…
- Conditions
- Cardiovascular Disease, Asthma, COPD, Interstitial Lung Disease Due to Systemic Disease
- Trial name
- EPIC-AIR (NCT07500948)
- Testing
- Progressive Walking Exercise Programme, Real-time air quality information and guidance
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Atypical Facial Pain or Atypical Odontalgia
Assessment and Treatment Patients With Atypical Facial Pain Trough Repetitive Transcranial Magnetic Stimulation
Atypical Facial Pain is a chronic condition and presents controversies during diagnostic and treatment, between specialist not have consensus about the pathophysiology.
- Trial name
- EMTr-AFP (NCT01746355)
- Testing
- rTMS
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Acute Pain, Chronic Pain
The Use of Venlafaxine in Reducing Pain in Primary Total Knee Replacement
Patients experience pain after their knee replacement surgery - and some may continue to experience persistent pain long after their knee replacement surgery.
- Conditions
- Acute Pain, Chronic Pain, Knee Pain Chronic, Neuropathic Pain
- Trial name
- NCT05023278
- Testing
- Venlafaxine 37.5 MG
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Periodontitis, Adult
Association of Periodontitis With Oral Health Related Quality of Life
Objective: The aim of this study was to investigate the impact of periodontitis on oral health-related quality of life (OHQoL) and the factors may associated with OHQoL.
- Trial name
- NCT04240015
- Testing
- Oral-Dental Health-Related Quality of Life-United Kingdom (OHRQoL-UK) scale
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baskent University
Chronic Periodontitis
Clinical, Microbiological and Biochemical Effects of the Antimicrobial Photodynamic Therapy
The goal of this study is to determine if patients with chronic periodontitis when undergoing with scaling and root planing (SRP) plus photodynamic therapy in comparison with SRP alone result in improved clinical, microbiological…
- Trial name
- NCT01532674
- Testing
- Antimicrobial photodynamic therapy (Periowave) and scaling and root planing, scaling and root planing
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Francisco Alpiste Illueca
Proprioceptive Postural Control, Chronic Obstructive Pulmonary Disease
Proprioceptive Postural Control and Chronic Obstructive Pulmonary Disease (COPD)
Proprioceptive weighting changes may explain differences in postural control performance. In addition, the respiratory movement has a disturbing effect on postural balance.
- Trial name
- NCT01505543
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Depression, Anxiety, Fatigue
Feasibility Study of a Modified Yoga Program for Elders
The purpose of this study is to determine whether a modified yoga program helps improve pain and function in elders age 65 years or older living in an assisted living community.
- Conditions
- Depression, Anxiety, Fatigue, Pain, Chronic, Sleep
- Trial name
- NCT04343625
- Testing
- Modified yoga class
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Obstructive Pulmonary Disease
Associations Between Air Pollutants Exposures and Respiratory System Study
Epidemiological investigations has suggested exposure to air pollution linked with respiratory disease, especially chronic obstructive pulmonary disease. However, the potential mechanisms of adverse effects remains scare.
- Trial name
- NCT02964117
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Chronic Traumatic Encephalopathy
The DIAGNOSE-CTE Research Project
This is a study to develop methods of diagnosing chronic traumatic encephalopathy (CTE) during life, as well as to examine possible risk factors for this neurodegenerative disease.
- Trial name
- DIAGNOSE-CTE (NCT02798185)
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Boston University
Chronic Renal Insufficiency, Hemodialysis
Effect of a Concurrent Physical Exercise Program in Hemodialysis Patients
Concurrent physical exercise is the method of combining strength and endurance that can be worked with in one session or in an exercise program.
- Trial name
- NCT06664385
- Testing
- concurrent physical exercise
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pedro Julian Flores Moreno
Heart Failure, Sarcopenia
Mechanism of Sarcopenia in Heart Failure
The aim of the study is to provide information on the interaction between socioeconomic factors, daily physical activity, nutrition and lifestyle on loss of muscle mass and muscle function in patients with heart failure.
- Conditions
- Heart Failure, Sarcopenia, Cachexia
- Trial name
- MUSCLE-CHF (NCT05063955)
- Where
- Denmark
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Chronic Periodontitis
Grape Seeds Extract Gel as an Adjunct for the Treatment of Chronic Periodontitis
The aim of this study was to formulate a mucoadhesive gel of grapes seed extract (GSE) followed by short-term clinical study for the effectiveness of this gel onto the pocket depth (PD), plaque index (PI), gingival index (GI)…
- Trial name
- NCT02767115
- Testing
- 2% GSE mucoadhesive gel, GSE free mucoadhesive gel
- Where
- Saudi Arabia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Chronic Kidney Disease
Peer-mentoring, Quality of Life and Caregiver Burden in Patients With Chronic Kidney Disease and Their Caregivers
Receiving supportive mentoring from well-adjusted individuals who share similar experiences has had a positive influence on adjustment with some chronic diseases.
- Trial name
- NCT02429115
- Testing
- Mentoring
- Where
- United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
COPD, COPD Exacerbation
Isolation of Circulating Pulmonary Cells in COPD and Its Relationship With Clinical Relevant Outcomes (IbICEnCa)
We have demonstrated for the very first time that it is possible to isolate CPCs (circulating pulmonary cells) in patients with COPD in a sample of 17 patients (with a recovery rate of nearly 40%) and none of 10 healthy, non…
- Conditions
- COPD, COPD Exacerbation, COPD, Severe Early-Onset
- Trial name
- IbICEnCa (NCT03591978)
- Testing
- Isolation of Circulating Pulmonary Cells in peripheral blood
- Where
- 4 sites in Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Stroke
Treatment of Chronic Stroke With IpsiHand
The ultimate goal of this project is to develop a functioning and clinically feasible method for restoring function to motor-impaired stroke survivors. This ultimate goal will be approached through two different means.
- Trial name
- NCT02552368
- Testing
- IpsiHand Device
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
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