Clinical trials: Chronic Constipation
Inguinal Hernia, Constipation
Relationship Between Constipation and Inguinal Hernia
The purpose of this study is to asses the effect of chronic constipation on formation of inguinal hernia using Constipation Severity Scale.
- Trial name
- NCT02749682
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Siverek Devlet Hastanesi
Chronic Constipation
Acupuncture for Chronic Constipation
Since there have been few advances for constipation in laxative treatment in the last 50 years, this study is designed to evaluate the efficacy and safety of acupuncture for patients with chronic constipation based on the theory…
- Trial name
- NCT00746200
- Testing
- (electro)acupuncture
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Constipation Chronic Idiopathic
Evaluation of the Triple Management Program in the Management of Functional Chronic Constipation in Children
Abstract Background: Chronic constipation is a common disease in children, 3% all children visit gastroenterology clinics with different types and complains.
- Trial name
- NCT06082622
- Testing
- laxatives
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Minia University
Chronic Constipation
Exploring the Potential Benefits of Probiotic Yogurt
This study aims to evaluate the effect of a high-activity probiotic yogurt on improving symptoms of chronic constipation, observing its regulatory effects on the gut microbiota and the incidence of adverse reactions in study…
- Trial name
- NCT06847919
- Testing
- Probiotic yogurt group, Yogurt control group
- Where
- China
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Irritable Bowel Syndrome
Prevalence of Intestinal Parasitic Infections in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is common medical disorder and represent a group of diseases of the gastrointestinal tract that is characterized by chronic abdominal pain , bloating , passage of mucus or straining with bowel…
- Trial name
- NCT05830370
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Chronic Idiopathic Constipation
This Study Aims to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Properties and Food Effect of IN-114199 in Healthy Participants
This study aims to evaluate the safety, tolerability, pharmacokinetic and pharmacodynamic properties and food effect of IN-114199 in healthy participants
- Trial name
- NCT06736912
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Chronic Constipation
Effectiveness and Safety of Probiotic in Regulating Chronic Constipation
To evaluate the effectiveness and safety of the use of probiotics as food supplements in regulating the intestinal habit of subjects with chronic constipation, in comparison with placebo.
- Trial name
- NCT05980988
- Testing
- Probiotic
- Where
- 2 sites in Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Constipation
Lubiprostone and Mucus Secretion in Patients With Chronic Constipation
The investigators hypothesize that the symptoms of chronic constipation in some patients are developed due to diminished production and secretion of the alimentary tract mucus resulting in poor lubrication.
- Trial name
- NCT01447849
- Testing
- lubiprostone
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Constipation, Constipation - Functional
The Impact of Respiratory Muscle Training and Patient Education on Chronic Constipation Outcomes
The primary aim of this study will be to determine if a respiratory muscle training program that includes both inspiratory muscle training (IMT) and expiratory muscle training (EMT), targeted at improving respiratory muscle…
- Conditions
- Constipation, Constipation - Functional, Dyssynergia
- Trial name
- NCT05823259
- Testing
- Hybrid Telehealth Program: Respiratory Muscle Training and Patient Education, Standard Physical Therapy Care
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Miami
Chronic Constipation
Effects of Oral PEG 3350 on Electrolyte Balance
The study is to evaluate the influence of three different doses of PEG 3350 with or without electrolytes on the electrolyte balance in patient volunteers with confirmed chronic constipation.
- Trial name
- NCT00868985
- Testing
- PEG 3350 plus electrolytes, PEG 3350 without electrolytes
- Where
- Romania
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Norgine
Chronic Constipation
Reflexology for Chronic Constipation
The purpose of this study is to examine if the use of reflexology can alleviate chronic constipation. The trial will last 26 week per patient, 2 week of screening period, 12 weeks of treatment and 12 weeks of follow up.
- Trial name
- NCT01599156
- Testing
- Reflexology
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Endometriosis
ENDOMET - Novel Diagnostic Tools and Treatments for Endometriosis
Endometriosis is a chronic disease characterized by the presence of functional endometrial glands and stroma in ectopic locations outside the uterine cavity.
- Trial name
- ENDOMET (NCT01301885)
- Testing
- Laparoscopy/laparotomy
- Where
- 4 sites in Finland
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Chronic Constipation
Effect to Linaclotide on Colonic Motility
This study aim was to evaluate the effect of Linaclotide, a pharmacological treatment normally used to treat functional constipation or irritable bowel syndrome with predominant constipation, on colonic motility as assessed by…
- Trial name
- NCT06989268
- Testing
- Linaclotide 290 micrograms
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Constipation, Constipation
Safety and Efficacy of Linaclotide in Patients With Chronic Constipation and Prominent Abdominal Bloating
The purpose of this study is to evaluate the efficacy and safety of linaclotide compared with placebo in patients with chronic constipation (CC) and prominent abdominal bloating.
- Trial name
- NCT01642914
- Testing
- Linaclotide 290 micrograms, Linaclotide 145 micrograms
- Where
- 151 sites in United States, Canada
- Volunteers
- 487 people, healthy volunteers welcome
- Sponsor
- Forest Laboratories
Chronic Constipation
The Combined Seed Extracts of Cassia Obtusifolia Linne and Foeniculum Vulgare Mill in Patients With Chronic Constipation
The investigators will conduct a randomized, double-blind, placebo-controlled study to investigate the effects and safety of the combination seed extracts of Cassia obtusifolia Linne and Foeniculum vulgare Mill in patients with…
- Trial name
- NCT05548842
- Testing
- The combined seed extracts of Cassia obtusifolia Linne and Foeniculum vulgare Mill
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Constipation
Risk Factors for Inadequate Bowel Preparation in Patients With Chronic Constipation
Chronic constipation is one of the risk factors of inadequate bowel preparation, which could influence the effect of colonoscopy.
- Trial name
- NCT02842411
- Where
- 4 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Constipation
A Study to Evaluate the Effects of a Natural Supplement in Adults With Chronic Functional Constipation
Constipation is common in the general population, especially in women and in the elderly. Hard stool is a complaint often associated with constipation, which suggests that stool softening would provide a major benefit in the…
- Trial name
- NCT02073006
- Testing
- Natural Fibre Supplement
- Where
- Ireland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Atlantia Food Clinical Trials
Slow Transit Constipation, Colonic Transit
Validation of New Type Radiopaque Marker in The Evaluation of Colonic Transit Time
The goal of this clinical trial is to learn if the local made colonic transit capsule can be use to diagnose slow transit constipation.
- Conditions
- Slow Transit Constipation, Colonic Transit, Chronic Constipation, Colonic Transit Capsule
- Trial name
- NCT06850415
- Testing
- Siriraj gastrointestinal transit capsule, Sitz-Markers
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Constipation
Metagenome Analysis of Gut Microbiota in CC Patients
Constipation is a heterogeneous and multifactorial disease, influenced by a number of different genetic and environmental factors.
- Trial name
- NCT02395484
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China