Clinical trials: Chronic Coronary Disease
Cancer, Congestive Heart Failure
Outlook Quality of Life Intervention
The purpose of this study is to determine whether discussions of life story, forgiveness, and future goals improve quality of life for patients with serious illness.
- Conditions
- Cancer, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00784095
- Testing
- Life completion and preparation, Attention Control
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Coronary Artery Disease, Ischemic Heart Disease
Coronary and Structural Interventions Ulm - Coronary Chronic Total Occlusions
To evaluate the long-term results after recanalization of coronary chronic total occlusions.
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Stable Angina
- Trial name
- CSI-Ulm-CTO (NCT02162082)
- Testing
- stent or scaffold
- Where
- Germany
- Volunteers
- 198 people
- Sponsor
- University of Ulm
Chronic Heart Failure, Iron Deficiency, Latent
The Prevalence of Iron Deficiency and the Effectiveness of Ferinject® in Patients With HFpEF (ID-HFpEF)
Observational cohort randomized controlled study to study the influence of correction of ID by intravenous injection of ferric carboxymaltose (Ferinject®) on quality of life indicators, functional status in a cohort of patients…
- Trial name
- ID-HFpEF (NCT05793996)
- Testing
- Ferinject, Diet therapy
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Cardiomyopathy, Renal Impairment
Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Diastolic Cardiomyopathy (Aim3)
To determine the effect of 12 weeks of chronic PDEV inhibition with Tadalafil versus placebo on basal cardiorenal and humoral function and on the integrated cardiorenal and humoral response to acute sodium loading in subjects…
- Trial name
- Aim 3 (NCT02058095)
- Testing
- Tadalafil
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Mayo Clinic
Stable Chronic Angina, Coronary Artery Disease
Effect of External Counter Pulsation on Coronary Artery Disease
Coronary artery disease (CAD) is prevalent worldwide and the leading cause of mortality of citizens, external counter pulsation (ECP) has been elucidated that it may release angina symptoms and improve the prognosis of CAD…
- Trial name
- ECP-CAD (NCT03075124)
- Testing
- External Counter Pulsation
- Where
- 4 sites in China
- Volunteers
- 380 people
- Sponsor
- Eighth Affiliated Hospital, Sun Yat-sen University
Chronic Coronary Syndrome
Intracoronary ECG ST-segment Shift Remission Time During Reactive Coronary Hyperemia
This study evaluates a new diagnostic approach based on intracoronary electrocardiogram (icECG) ST-segment shift remission time, denoted as τ-icECG (τ=tau, i.e., the remission half-time fitted by an exponential function to the…
- Trial name
- τ-icECG (NCT05583786)
- Testing
- Tracing intracoronary electrocardiogram
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Heart Diseases, HIV
T1 Mapping in HIV Patients With High and Low CD4+ Cell Counts
HIV-infection is associated with an increased risk for cardiovascular disease. Especially patients with low CD4+ counts have a higher incidence of structural heart disease.
- Trial name
- NCT02054494
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Chronic Heart Failure
Prediction of Outcomes in Patients With Chronic Heart Failure Based on Tissue Raman Spectroscopy
Chronic heart failure (CHF) is a syndrome complicating heart disease, the prevalence of which has reached epidemic levels. According to global statistics the most common causes of CHF are coronary heart disease (CHD): 26.5%…
- Trial name
- PROMETHEUS (NCT06393595)
- Testing
- surface enhanced Raman Spectroscopy
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Samara State Medical University
Hypertension in Pregnancy, Gestational Hypertension
Virtual Cardiac Wellness Program Following Hypertensive Disorders of Pregnancy
Hypertensive disorders of pregnancy (HDP) are now well-recognized risk factors for adverse outcomes in the postpartum period and for development of future cardiovascular disease (CVD).
- Conditions
- Hypertension in Pregnancy, Gestational Hypertension, Preeclampsia, Chronic Hypertension With Pre-Eclampsia
- Trial name
- NCT04998942
- Testing
- virtual cardiac wellness program
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Pulmonary Disease, Chronic Obstructive
Beta-Blockers for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary Disease
This is a multicenter, prospective, randomized, double-blind, placebo-controlled trial that will enroll 1028 patients with at least moderately severe COPD over a three year period and follow them at regular intervals for one…
- Trial name
- NCT02587351
- Testing
- Metoprolol succinate
- Where
- 27 sites in United States
- Volunteers
- 532 people
- Sponsor
- University of Minnesota
Atrial Fibrillation, Diastolic Dysfunction
Atrial Fibrillation: Chronic Beta-blocker Use Versus As-needed Rate Control Guided by Implantable Cardiac Monitor
The goal of this study is to test the feasibility of guiding as-needed pharmacological rate control of atrial fibrillation (AF) by implantable cardiac monitors and to assess the impact of continuous beta-blocker therapy versus…
- Conditions
- Atrial Fibrillation, Diastolic Dysfunction, HFpEF - Heart Failure With Preserved Ejection Fraction
- Trial name
- NCT05745337
- Testing
- As needed pharmacological rate control with beta-blocker (metoprolol tartrate, metoprolol succinate) or calcium channel blocker (diltiazem, verapamil)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Vermont
Multiple Chronic Diseases Among Diabetes Mellitus, Chronic Obstructive Pulmonary Diseases and Heart Failure
Life-long Monitoring of Frail Patients With Chronic Diseases
The purpose of this study is to evaluate whether telemonitoring of frail patients with chronic diseases produces benefits in terms of reduced readmissions, improved health related quality of life, and improved health status.
- Trial name
- NCT01608932
- Testing
- Telemonitoring for frail patients with chronic diseases
- Where
- 7 sites in Italy
- Volunteers
- 152 people
- Sponsor
- Regione Veneto
Orthopedic Disorder, Neurologic Disorder
Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions
To determine the safety and efficacy of Amniotic and Umbilical Cord Tissue for the treatment of the following condition categories: Orthopedic, Neurologic, Urologic, Autoimmune, Renal, Cardiac and Pulmonary Conditions.
- Conditions
- Orthopedic Disorder, Neurologic Disorder, Urologic Diseases, Erectile Dysfunction
- Trial name
- NCT03899298
- Testing
- Amniotic and Umbilical Cord Tissue Procedure
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- R3 Stem Cell
COPD, COPD Exacerbation Acute
The Italian Registry of Patients With Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a treatable but debilitating medical condition associated with persistent symptoms and chronic airflow obstruction.
- Conditions
- COPD, COPD Exacerbation Acute, Comorbid Chronic Lung Disease on Heart Failure, Mortality
- Trial name
- ICoRe (NCT06652776)
- Testing
- Pharmacological treatment
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- University of Milan
Kidney Disease, Chronic, Heart Failure
New Heart Failure Biomarkers in Early Stage Chronic Kidney Disease-Mineral and Bone Disorder
the objective of this study is to : -Determinate wether the circulating levels of iFGF23 and klotho can be a predictor biomarker of HF in patients with CKD-MBD.
- Trial name
- CKD-MBD-HF (NCT03307707)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Pr. Semir Nouira
Atrial Fibrillation
Decision Aids for Patients With Nonvalvular Chronic Atrial Fibrillation (DA4AFib)
The researchers are observing subject and clinician interaction in order to develop future education materials that will help patients and clinicians discuss atrial fibrillation and options to treat it.
- Trial name
- (DA4AFib) (NCT03744936)
- Testing
- Feedback
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Mayo Clinic
Chronic Heart Failure
The IMPULSE Study: Pilot
Continuous-flow (CF) left ventricular assist devices (LVADs) are an important tool in the treatment of end-stage heart failure, affording patients significantly improved quantity and quality of life.
- Trial name
- IMPULSE (NCT02044471)
- Testing
- Remote Ischemic Conditioning (using Sphygmomanometer)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine
Thromboembolism, Cardiac Event
Influence of Cardiac Implantable Electronic Devices on the Hemostatic System
The hemostasis system is one of the many biological systems of the human body, designed to preserve the liquid state of blood and prevent its loss during vascular injuries.
- Conditions
- Thromboembolism, Cardiac Event, Hemostatic Disorder
- Trial name
- NCT04499612
- Testing
- Cardiac implantable electronic device implantation., Cardiac implantable electronic device replace., Duplex ultrasound.
- Where
- Russia
- Volunteers
- 250 people
- Sponsor
- Ryazan State Medical University
Chronic Kidney Disease, Heart Failure With Preserved Ejection Fraction (HFPEF)
The Epidemiology and Pathophysiology of Kidney Disease in HFpEF With Obesity
This research study wants to learn about Chronic Kidney Disease (CKD) with Obesity, and Heart Failure with preserved Ejection Fraction (HFpEF) and better ways to evaluate these diseases.
- Conditions
- Chronic Kidney Disease, Heart Failure With Preserved Ejection Fraction (HFPEF), Obesity (Disorder)
- Trial name
- NCT07052539
- Testing
- High protein and sodium meal
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Heart Failure NYHA Class II, Heart Failure NYHA Class III
Baduanjin-eight-silken-movement With Self-efficacy Building for Patients With Chronic Heart Failure (BESMILE-HF Study)
Chronic heart failure (CHF) is a major and growing public health problem and poses economic burden on the society. There is a need for a safe, equipment-free, low-cost, and easily implemented exercise-based cardiac rehabilitation…
- Conditions
- Heart Failure NYHA Class II, Heart Failure NYHA Class III, Heart Failure
- Trial name
- BESMILE-HF (NCT03180320)
- Testing
- BESMILE-HF program, Usual medications
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
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