Clinical trials: Chronic Disease (Physical)
Metabolic Syndrome
Effect of MetS* on Cognitive Performance and Physical Activity (Metabolic Syndrome)
Metabolic syndrome (MetS) increases the risk of developing diabetes and cardiovascular disease risk factors that are linked with each other, which is a metabolic dysfunction, which contains a combination of multiple.
- Trial name
- NCT05702437
- Testing
- assessment of cognitive performance
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Ischemic Heart Disease Chronic, Diabetes Mellitus, Type 2
Lifestyle Intervention in Chronic Ischemic Heart Disease and Diabetes
Chronic ischemic heart disease and diabetes mellitus type II have one of the highest morbidity and mortality rates. Especially in the presence of both diseases, these risks increase exponentially.
- Trial name
- LeIKD (NCT03835923)
- Testing
- lifestyle intervention, usual care
- Where
- 10 sites in Germany
- Volunteers
- 502 people
- Sponsor
- Techniker Krankenkasse
Renal Failure Chronic Requiring Hemodialysis, Poor Quality Sleep
BIA-Guided Dry Weight Assessment on Sleep Quality in Chronic Hemodialysis Patients
Based on many previous data proving hypervolemia in chronic hemodialysis patients could lead to sleep apnea and poor sleep quality.
- Trial name
- BEDTIME (NCT02825589)
- Testing
- BIA
- Where
- Thailand
- Volunteers
- 19 people
- Sponsor
- Mahidol University
Arthritis, Asthma
Mobility Assessment in Multi-morbidity
Multimorbidity (the presence of two or more coexisting long-term conditions) is a significant challenge facing the NHS, especially given UK's ageing population and the association with high levels of illness burden and healthcare…
- Conditions
- Arthritis, Asthma, Atrial Fibrillation, Bronchiectasis
- Trial name
- Multi-mobility (NCT06473168)
- Volunteers
- 55 people
- Sponsor
- Northumbria University
Sclerosis, Multiple
Can Fatigability Neuromuscular Explain Chronic Fatigue in People With Multiple Sclerosis?
Chronic fatigue is the most common and debilitating symptom in multiple sclerosis patients. This chronic fatigue affects their quality of life by decreasing their capacity to perform simple tasks of daily life.
- Trial name
- FatSEP (NCT03983720)
- Testing
- Evaluation of degree chronic fatigue., Questionnaires, Blood sample
- Where
- France
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
End-Stage Renal Disease, Hemodialysis Complication
The Effect of Home-based Exercise on Postural Abnormalities
This study evaluates the effects of synchronous home-based tele-exercise on postural abnormalities (FHP and hyper-kyphosis) in dialysis patients.
- Trial name
- NCT06877962
- Testing
- Home-based Tele Exercise
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Pardis Specialized Wellness Institute
Cerebrovascular Accident
Hybrid Approach to Unilateral vs. Bilateral Upper Limb Rehabilitation in Subacute and Chronic Stroke
In the unilateral vs. bilateral hybrid rehabilitation trials, we will conduct two separate clinical trials: one to recruit subacute stroke patients and another to recruit chronic stroke patients.
- Trial name
- NCT01908361
- Testing
- Unilateral Hybrid (InMotion3 plus CIT) Intervention, Bilateral Hybrid (BMT plus BAT) Intervention, Conventional Rehabilitation
- Where
- Taiwan
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Chronic Disease, Child
Motivated to Move: A Study to Determine the Feasibility of Self-Monitoring Physical Activity in Youth
Children with a medical condition don't get enough exercise, which can lead to even more health problems in childhood and adulthood.
- Conditions
- Chronic Disease, Child, Adolescent
- Trial name
- NCT03970369
- Testing
- Usual care, Monitor
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Chronic Disease
Adapted Physical Activity Centre (in The) CITY for Elders Aged 70 and Over with At Least One Long Term Illness
Elders aged 70 and over, living in Toulouse, with a chronic disease identified by the French social insurance as an Affection Longue Durée will be eligible to a 4 months physical activity program in a primary health center.
- Trial name
- CAPACITY70 (NCT04644861)
- Testing
- Program of adapted physical activity
- Where
- France
- Volunteers
- 37 people
- Sponsor
- University Hospital, Toulouse
Hypoxia, COPD
Intelligent Oxygen Therapy During Activities of Daily Living
The aim of this study is to assess whether an auto-titrating oxygen system can maintain constant oxygen saturations (SpO2) in patients who are on long-term oxygen therapy (LTOT) during activities of daily living.
- Conditions
- Hypoxia, COPD, Hyperoxia
- Trial name
- NCT02683486
- Testing
- Intelligent oxygen therapy (an auto-titrating oxygen system), Long-term oxygen therapy
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Imperial College London
Protein-Energy Malnutrition, Kidney Failure, Chronic
Egg Albumin-Based Protein Supplement Versus Renal-specific Supplement in Hemodialysis Patients
Malnutrition is seen frequently in hemodialysis units in most developing countries. Malnutrition increases morbidity and mortality in this population and its treatment improves patient survival and health status The purpose of…
- Conditions
- Protein-Energy Malnutrition, Kidney Failure, Chronic, Hemodialysis
- Trial name
- NCT01981083
- Testing
- Egg albumin-based protein supplement, Renal-specific oral supplement
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Centro Medico Lic Adolfo Lopez Mate
Leukaemia (Chronic)
What is the Impact of TKI on Thyroid Function in CML Patients?
Evaluation of the impact of various TKI on thyroid function in patients diagnosed with cml
- Trial name
- NCT07200882
- Volunteers
- 76 people
- Sponsor
- Assiut University
Renal Insufficiency, Chronic, Diabetes Mellitus, Type 2
Pilot Assessment of the Effects of Bardoxolone Methyl on Renal Perfusion, Systemic Haemodynamics and Cardiac Function in Patients With Chronic Kidney Disease and Type 2 Diabetes
This study is to evaluate the variability of several pharmacodynamic measures of kidney function, cardiovascular function, cerebral perfusion, and haemodynamics.
- Trial name
- NCT01551446
- Testing
- Bardoxolone Methyl
- Sponsor
- Biogen
Cerebral Palsy, Stroke
Reliability of the Melbourne Assessment
The aim of the study is to investigate the reliability of the Melbourne Assessment.
- Conditions
- Cerebral Palsy, Stroke, Traumatic Brain Injury, Meningomyelocele
- Trial name
- NCT02595411
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Children's Hospital, Zurich
Pulmonary Disease, Chronic Obstructive
Comparing the Efficacy of Tiotropium + Olodaterol Fixed Dose Combination (FDC) Over Tiotropium in Improvement of Lung Hyperinflation, Exercise Capacity and Physical Activity in Japanese COPD Patients
This is a multi-centre, randomised, double-blinded, active-controlled, 2-way cross over trial to assess the effects of once daily administration of orally inhaled tiotropium + olodaterol FDC or tiotropium (both delivered by the…
- Trial name
- NCT02629965
- Testing
- tiotropium, olodaterol
- Where
- 43 sites in Japan
- Volunteers
- 184 people
- Sponsor
- Boehringer Ingelheim
Chronic Liver Disease (CLD), Liver Cirrhosis
Heart Problems in Children With Chronic Liver Disease
Chronic liver disease (CLD) in children can sometimes lead to complications in other parts of the body, including the heart. The primary purpose of this observational study is to assess the presence and type of cardiac problems…
- Conditions
- Chronic Liver Disease (CLD), Liver Cirrhosis, Cardiac Abnormalities, Portopulmonary Hypertension
- Trial name
- NCT07502196
- Volunteers
- 60 people
- Sponsor
- Assiut University
Chronic Respiratory Acidosis
Respiratory Stabilization in Chronic Acidosis Before Bronchofiberoscopy & Non-Invasive Ventilation Effectivenes
Bronchofiberoscopy (FOB) is a minimally invasive and safe procedure performed for diagnostic and therapeutic purposes. FOB frequently impairs respiratory function, which may lead to possible exacerbation of respiratory failure.
- Trial name
- NCT06970002
- Testing
- Use of NIV during FOB as a respiratory support method, Use of HFNC during FOB as a respiratory support method
- Volunteers
- 210 people
- Sponsor
- Medical University of Silesia
Cerebral Palsy, Neurologic Disorder
Neural Mobilization and Cerebral Palsy
Objective: To assess the effect of neural mobilization applied to the lower limbs, compared to conventional physical therapy, in children diagnosed with Cerebral Palsy.
- Trial name
- NEUROREHAB (NCT06485830)
- Testing
- Neural mobilization of the lower limb, Conventional physical therapy
- Where
- 2 sites in Spain
- Volunteers
- 40 people
- Sponsor
- University of Seville
Pseudo Obstruction
ACTG2/FLNA Testing Yield in Adult Idiopathic Chronic Intestinal Pseudo-Obstruction (CIPO) With Reduced/Absent Distal Esophageal Contractility
To assess the diagnostic yield of Sanger sequencing for ACTG2 and FLNA genes evaluation on blood or saliva sample in patients with idiopathic CIPO in which high-resolution esophageal manometry (HRM) shows reduced (DCI <450…
- Trial name
- CIPO_GEN (NCT07448753)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Marina Coletta
Cerebral Palsy, Self Care
Psychometric Properties of the Self-Care Assessment Scale for 3-6 Year Old Children With Cerebral Palsy-Parent Form
This study is a methodological study to develop the self-care assessment scale-parent form of children with CP aged 3-6 years and test its validity and reliability. Q1.
- Trial name
- NCT06380829
- Testing
- Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people
- Sponsor
- Aydin Adnan Menderes University
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