Clinical trials: Chronic Disease Lung
COPD
Case Method Education on COPD to General Practitioners
Background: COPD is an inflammatory and chronic obstructive lung disease, mainly caused by smoking. Most patients with COPD are discovered and treated in primary health care.
- Trial name
- PRIMAIR (NCT02213809)
- Testing
- Case method education in COPD, Traditional education in COPD
- Where
- Sweden
- Volunteers
- 822 people
- Sponsor
- Karolinska Institutet
PASC Post Acute Sequelae of COVID-19
Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC)
This study uses total-body [¹⁸F]F-AraG PET/CT imaging to investigate immune activation and vascular changes in individuals with post-acute sequelae of SARS-CoV-2 infection (PASC), also known as Long COVID.
- Trial name
- NCT07076862
- Testing
- A.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static), A.2 - [¹⁸F]F-AraG PET/CT (60-min dynamic only), B.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static)
- Where
- 2 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Post-COVID ME/CFS
Repeat Immunoadsorption Post Covid ME/CFS
The evidence for an autoimmune etiology in postinfectious myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is growing.
- Trial name
- NCT05629988
- Testing
- IA with TheraSorb ® column
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Charite University, Berlin, Germany
Chronic Obstructive Pulmonary Disease
Study on Impact of Maximal Strength Training in Patients With COPD
In the context of pulmonary rehabilitation of COPD patients, recent guidelines and metanalysis describe that Resistance Training (RT) can be successfully performed alone or in conjunction with Endurance Training (ET) without…
- Trial name
- NCT03799354
- Testing
- Maximal strenght training (MST) plus endurance training (ET), Endurance training (ET)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Chronic Mechanical Neck Pain
Chiropractic Manual Therapy and Neck Pain
Eligible subjects with chronic neck pain will be randomly allocated to one of two intervention groups: real vs control spinal manipulation. They will receive three intervention sessions.
- Trial name
- NCT01772966
- Testing
- Spinal manipulation
- Where
- Canada
- Volunteers
- 319 people
- Sponsor
- Canadian Memorial Chiropractic College
Post-COVID-19 Syndrome, Back Pain
Kinesiotaping Versus Physiotherapy for Post-Covid-19 Back Pain
Objective: This study aims to compare and evaluate the effectiveness of kinesiotaping and traditional physiotherapy methods, which are frequently used in the treatment of musculoskeletal diseases, on mid-back pain (MBP) developed…
- Conditions
- Post-COVID-19 Syndrome, Back Pain, Musculoskeletal Pain
- Trial name
- NCT07744451
- Testing
- Kinesiotaping, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Medipol University
Pulmonary Disease, Chronic Obstructive
A Study Based on Health Insurance Data About the Treatment of Patients Who Have Been Newly Diagnosed With Chronic Obstructive Pulmonary Disease (COPD)
A retrospective analysis study in COPD patients for an exact follow-up period of 12 months (in subgroup analyses: 24 and 36 months); censoring of patients will only be done in case a patient died during the respective follow-up…
- Trial name
- NCT04097223
- Where
- Germany
- Volunteers
- 17,464 people
- Sponsor
- Boehringer Ingelheim
COPD
myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home
Parallel-group, prospective, randomized, controlled phase III trial of home High flow Nasal Therapy (HFNT) via myAirvo 3 plus usual COPD medical care vs.
- Trial name
- NCT05204888
- Testing
- myAirvo3, Pulse oximeter
- Where
- 27 sites in United States, Canada
- Volunteers
- 642 people
- Sponsor
- Temple University
Pulmonary Disease, Chronic Obstructive
A Randomized Study, Comparing Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Single Inhaler Triple Therapy, Versus Multiple Inhaler Therapy (Budesonide/Formoterol Plus Tiotropium) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
The primary purpose of this study is to evaluate lung function and health related quality of life (HRQoL) after 84 days of treatment with a single inhaler triple therapy combination of FF/UMEC/VI [100/62.5/25 microgram (mcg)]…
- Trial name
- NCT03478683
- Testing
- budesonide/formoterol, albuterol/salbutamol, FF/UMEC/VI
- Where
- 57 sites in United States, Czechia and 2 more
- Volunteers
- 729 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease
Multidimensional Individualized Nutritional Therapy for Individuals with Severe COPD
Individuals with severe chronic pulmonary disease often life isolated with a high burden of symptoms. Nutritional risk and low quality of life are common, and both associated with increased societal cost and poor prognosis.
- Trial name
- MINDNUT (NCT04873856)
- Testing
- Intervention
- Where
- Denmark
- Volunteers
- 87 people
- Sponsor
- Nordsjaellands Hospital
Chronic Obstructive Pulmonary Disease
Thora-3DI™ for Evaluation of Severity of Chronic Obstructive Pulmonary Disease (COPD)
To demonstrate differences in tidal breathing patterns measured by SLP(Structured Light Plethysmography) between healthy subjects and COPD (chronic obstructive pulmonary disease).
- Trial name
- SLPCOPD (NCT03492359)
- Testing
- Thora-3Di, Body Plethysmography, Spirometry
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Landon Pediatric Foundation
COPD, Obesity &Amp; Overweight
The Impact of a Weight Reduction Intervention on Clinical Outcomes in Patients With Obesity and COPD
Obesity and COPD are increasingly common and often coexist, worsening health outcomes such as reduced lung function, exercise capacity, and increased systemic inflammation.
- Trial name
- NCT07159594
- Testing
- Energy restriction
- Volunteers
- 70 people
- Sponsor
- Sahlgrenska University Hospital
COPD Exacerbation, Pulmonary Rehabilitation
Virtual Reality in COPD Exacerbation
In addition to conventional pulmonary rehabilitation, virtual reality will be applied during the hospitalization period of individuals hospitalized for COPD exacerbation.
- Trial name
- NCT05687396
- Testing
- virtual reality, conventional pulmonary rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Pamukkale University
COPD (Chronic Obstructive Pulmonary Disease)
Effect of Aronia Berry Consumption on Inflammatory Parameters
The study will aim to evaluate the effects of consuming freeze-dried aronia berries as an adjunct to medical treatment in patients with chronic obstructive pulmonary disease (COPD), focusing on anti-inflammatory, respiratory, and…
- Trial name
- NCT06702696
- Testing
- Black chokeberry (Aronia melanocarpa)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Amasya University
Chronic Obstructive Pulmonary Disease
Evaluate the Safety of MN-221 in Subjects With Stable Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
The objective of this clinical study is to determine the safety of intravenous MN-221 compared to placebo when administered in subjects diagnosed with stable moderate to severe COPD.
- Trial name
- NCT01013142
- Testing
- MN-221 (Dose Group 1), MN-221 (Dose Group 2), MN-221 (Dose Group 3)
- Where
- 7 sites in United States
- Volunteers
- 48 people
- Sponsor
- MediciNova
Chronic Obstructive Pulmonary Disease (COPD)
Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations
The purpose of this study is to investigate the safety and tolerability of Metformin and how it changes blood markers associated with aging in persons who have chronic obstructive pulmonary disease (COPD) who do not have diabetes.
- Trial name
- INSPIRE-COPD-E (NCT07275359)
- Testing
- Metformin
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Duke University
Pulmonary Disease, Chronic Obstructive
Determining Optimal Free Dose Combination of Tiotropium Bromide and BI 1744 CL in Chronic Obstructive Pulmonary Disease (COPD)
The primary objective of this study is to determine the optimum once daily dose of BI 1744 CL and tiotropium in free dose combination (delivered by the Respimat inhaler) after four week treatment in patients with COPD.
- Trial name
- NCT01040403
- Testing
- olodaterol (BI 1744) low, low tiotropium bromide, olodaterol (BI 1744) high
- Where
- 33 sites in Canada, Germany and 2 more
- Volunteers
- 233 people
- Sponsor
- Boehringer Ingelheim
Copd, Asthma
Strados System at Center of Excellence
Listening to breath sounds with the stethoscope/auscultation is used by pulmonary physicians in conjunction with pulmonary function, signs and symptoms, oxygen saturation and diagnostic testing to admit, follow and discharge…
- Conditions
- Copd, Asthma, Covid19
- Trial name
- NCT04485741
- Testing
- RESP
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Strados Labs, Inc.
Chronic Obstructive Pulmonary Disease (COPD)
A Study to Investigate the Pharmacokinetics, Safety and Tolerability of CHF 5993 pMDI in Subjects With Renal Impairment.
The study is performed to characterize the pharmacokinetics of glycopyrrolate bromide after single administration of CHF 5993 pressurised Metered Dose Inhaler (pMDI) in subjects with different level of renal impairment in…
- Trial name
- TRIPLE10 (NCT02040597)
- Testing
- Beclometasone/Formoterol/Glycopyrrolate
- Where
- 2 sites in Poland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
COPD
MCID in 30 STS Test After PR in COPD Patients
The sit-to-stand test (STST) is a feasible alternative for measuring peripheral muscle strength of the lower limbs. Our aim was to evaluate, in Chronic Obstructive Pulmonary Disease (COPD) patients, the minimal clinically…
- Trial name
- COPD (NCT03627624)
- Testing
- Pulmonary rehabilitation
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 96 people
- Sponsor
- elisabetta zampogna
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