Clinical trials: Chronic Disease of Cardiovascular System
Chronic Lower Leg Ulcer, Diabetic Lower Extremity Ulcers
Use of Hydroprep Wound Therapy With Motion Negative Pressure Therapy for Treatment of Chronic Lower Extremity Wounds
Use of a motorized waterjet to debride wounds to improve healing outcomes.
- Conditions
- Chronic Lower Leg Ulcer, Diabetic Lower Extremity Ulcers, Pressure Injuries, Traumatic Wounds and Injuries
- Trial name
- NCT07653165
- Testing
- Motion NPWT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- West Boca Center for Wound Healing
Graft Versus Host Disease, Leukemia
Stem Cell Transplant in Treating Patients With Hematological Cancer or Other Disorders
RATIONALE: Giving chemotherapy, such as fludarabine, busulfan, and cyclophosphamide, together with antithymocyte globulin before a donor stem cell transplant helps stop the growth of cancer and abnormal cells.
- Conditions
- Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00740467
- Testing
- anti-thymocyte globulin, busulfan, cyclophosphamide
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut Paoli-Calmettes
Stroke
Vestibular Training on Community Ambulation and Fall Risk in Stroke
Nearly half of individuals with stroke experience limitations in community ambulation, and 35.7% of community-dwelling stroke survivors experienced falls while walking, indicating that falls are common during routine daily…
- Trial name
- NCT07494500
- Testing
- Vestibular training, Conventional physical therapy
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Yang Ming Chiao Tung University
Chronic Subdural Hematoma, Anticoagulant-induced Bleeding
Management of Anticoagulants and Antithrombotics in Patients With CSDH
Primary objective of the study will be to compare, up to 6 months after surgery, number of relapses (post operative re-bleeding) or intracerebral hemorrhage (others than subdural hematomas) and thromboembolic or cardiovascular…
- Conditions
- Chronic Subdural Hematoma, Anticoagulant-induced Bleeding, Thromboembolic Stroke, Cardiovascular Stroke
- Trial name
- THERCA (NCT05079295)
- Testing
- CSDH evacuation
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University Hospital of Ferrara
Chronic Kidney Disease Requiring Chronic Dialysis
The Effect of High-flux Hemodialysis and On-line Hemodiafiltration on Endothelial Function.
The main aim of this project is to evaluate, in patients with chronic kidney disease (CKD5D), the role of adhesion molecules in leukocyte adhesion and transendothelial migration involved in atherogenesis.
- Trial name
- NCT03942744
- Testing
- on-line hemodiafiltration
- Where
- 2 sites in Spain
- Volunteers
- 88 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Cardiovascular Disease
Clinical Study to Assess High-DHA Fish Oil on Biomarkers of Cardiovascular Disease Risk in Adults on Statin Therapy
The objective of this study is to determine the acute and chronic [4-week] effects of a high-DHA fish oil supplement on fasting and post-prandial (post-meal) biomarkers of cardiovascular disease risk, in adults on Statin therapy.
- Trial name
- NCT01690312
- Testing
- Fish Oil
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
Venous Insufficiency (Chronic)(Peripheral), Venous Reflux
Adrenaline Reduces Ecchymoses and Hematomas and Improves Quality of Life After Classic Saphenous Vein Stripping
Aim of the present study is to investigate the efficiency of adrenaline (epinephrine) used locally in reducing and avoiding post-operative formation of subcutaneous ecchymoses and hematomas, in comparison with traditional…
- Conditions
- Venous Insufficiency (Chronic)(Peripheral), Venous Reflux, Venous Insufficiency of Leg, Venous Stasis
- Trial name
- ARESQOLSAVES (NCT04758728)
- Testing
- Great saphenous vein stripping and varicectomies, Epinephrine Topical, normal saline
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Junior Doctors Network-Hellas
Hypertension, Vascular Diseases
Streamlined Denervation With spYral For an Optimized Treatment (SPYRAL SWYFT) in Subjects With Uncontrolled Hypertension
The purpose of the SPYRAL SWYFT sub-study is to evaluate whether renal denervation with the Symplicity Spyral system performed in the main and first order branch renal arteries yields a shorter procedure time and is as effective…
- Conditions
- Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases
- Trial name
- SWYFT (NCT07115953)
- Testing
- Symplicity Spyral™ multi-electrode renal denervation system
- Where
- 21 sites in Australia, Belgium and 7 more
- Volunteers
- 130 people
- Sponsor
- Medtronic Vascular
Hypertension
A Prospective Nurse Cohort Study in Xiamen, China
The Nurse Cohort Study Xiamen (NCSX) is an open-ended prospective cohort study with very broad research aims. The primary objectives of the NCSX is planned to examine genetic, epigenetic, biological, psychological, social…
- Trial name
- NCT03799653
- Testing
- No intervention
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Xiamen University
Stroke, Cognitive Impairment
A Sitting Tai Chi Programme for Chronic Stroke Survivors With Post-stroke Cognitive Impairment
Introduction Stroke remains the third leading cause of death and disability combined. Post-stroke cognitive impairment (PSCI) is a common neurological sequela that may affect up to 80% of stroke survivors.
- Trial name
- NCT07512739
- Testing
- Tai Chi
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Chinese University of Hong Kong
Critical Limb Ischemia (CLI)
Intra-arterial Infusion of Autologous Bone Marrow Mononuclear Cells in Non-diabetic Patients With Critical Limb Ischemia (CLI).
Phase II Clinical Trial, a prospective, multicenter, open, randomized, parallel-group controlled with three levels of dose. The hypothesis of the test we propose is that the mononuclear cells of bone marrow provide progenitor…
- Trial name
- NCT01408381
- Testing
- Intraarterial Infusion of Autologous Bone Marrow Mononuclear Cells
- Where
- 5 sites in Spain
- Volunteers
- 38 people
- Sponsor
- Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud
Pain, Procedural (During Sternum Dressing on Infants), Arteriovenous Fistula
Cryotherapy for Reducing Fistula Puncture Pain in Hemodialysis Patients
People on hemodialysis need their arteriovenous fistula (a blood vessel access point) punctured with a needle three times a week, which can cause pain and worry.
- Conditions
- Pain, Procedural (During Sternum Dressing on Infants), Arteriovenous Fistula, Kidney Failure, Chronic
- Trial name
- CRYO-AVF (NCT07694271)
- Testing
- Usual Care (Room-Temperature Water Bag), Cryotherapy (Ice Pack), Lidocaine/Prilocaine Gel
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Taipei Medical University
Cardiovascular Disease, Heart Failure
Integration of Chronic Disease Rehabilitation Services Into Primary Care
The aim of PR1MaC is to establish a clinical intervention that will adapt and permanently integrate rehabilitation services into primary care settings, which would be the reference point in the health care system for people with…
- Conditions
- Cardiovascular Disease, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- PR1MaC (NCT01319656)
- Testing
- Support, management, educational, counselling, follow-up
- Where
- Canada
- Volunteers
- 326 people
- Sponsor
- Martin Fortin
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Israel Satellite Registry
BIOTRONIK - SaFety and Performance Registry for a diabetic patient population with the .bimus Eluting Orsiro Stent System Within daily clinical practice - III
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Diabetes Mellitus Type 1 or 2
- Trial name
- NCT01895712
- Where
- 6 sites in Israel
- Volunteers
- 120 people
- Sponsor
- BIOTRONIK Israel
Chronic Subdural Hematoma
Aspirin Continuation or Discontinuation in Conservative Treatment for Chronic Subdural Hematoma
This clinical study aims to learn about the efficacy and safety of aspirin continuation or discontinuation in conservative treatment for chronic subdural hematoma.
- Trial name
- NCT07240454
- Testing
- Aspirin Continuation, Aspirin Discontinuation
- Where
- 2 sites in China
- Volunteers
- 143 people
- Sponsor
- Tao Liu
Chronic Kidney Disease
Effect of Probiotic Consumption on Chronic Kidney Disease
Recent studies have demonstrated that the balance of intestinal microbiota is affected in chronic kidney disease (CKD), leading to a condition known as intestinal dysbiosis.
- Trial name
- NCT03400228
- Testing
- Probiotic, Maltodextrin
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Centro Universitário Univates
Diabetic Foot Ulcer
Longitudinal Study of Chronic Wounds Using Novel Wound Measurement Technologies
An open, non-randomised longitudinal study of diabetic foot ulcers receiving standardised treatment, over a 16 week period conducted at out-patient level, utilising novel optical wound measurement technologies.
- Trial name
- NCT02967900
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Michelson Diagnostics Ltd.
Chronic Pain, Fibromyalgia
Effects of Fasting on Self Efficacy
The study aims to investigate if a 7 day therapeutic fasting regimen will affect self-efficacy of patients with chronic diseases the effects of fasting on physical and mental well-being, quality of life and body awareness/image…
- Conditions
- Chronic Pain, Fibromyalgia, Rheumatoid Arthritis, Gout
- Trial name
- TheraFast (NCT02113111)
- Testing
- Fasting
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Universität Duisburg-Essen
Lower Extremity Chronic Ulcers in Diabetics
Evaluation of CureXcell® in Treating Lower Extremity Chronic Ulcers in Adults With Diabetes
Chronic foot ulcers are particularly prevalent in patients with underlying diabetes mellitus. These ulcers are reported to be the leading cause of hospitalization among people with diabetes.
- Trial name
- NCT01421966
- Testing
- CureXcell®
- Where
- 37 sites in United States, Canada and 1 more
- Volunteers
- 285 people
- Sponsor
- Macrocure Ltd.
End Stage Renal Disease, Hemodialysis
Immune Effects of Vitamin D in Hemodialysis Patients
The purpose of this study to examine whether vitamin D can reduce the activation of the immune system during dialysis. When activated, the immune cells release certain substances, called cytokines, which can be measured from…
- Conditions
- End Stage Renal Disease, Hemodialysis, Inflammatory Response, Cardiovascular Disease
- Trial name
- NCT00686751
- Testing
- paricalcitol
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Renal Research Institute
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