Clinical trials: Chronic Diseases in Adolescence
Chronic Disease, Child
Motivated to Move: A Study to Determine the Feasibility of Self-Monitoring Physical Activity in Youth
Children with a medical condition don't get enough exercise, which can lead to even more health problems in childhood and adulthood.
- Conditions
- Chronic Disease, Child, Adolescent
- Trial name
- NCT03970369
- Testing
- Usual care, Monitor
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Chronic Health Condition
Apply the (MyTransition) App In Transition
Moving from child care to adult care is a hard time for patients and their families. Parents of children with chronic conditions say they need more support around the time of changing care.
- Trial name
- ApplyIT (NCT03188224)
- Testing
- MyTransition app
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- McMaster University
Hepatitis B Virus (HBV)
Evaluation of Tenofovir Disoproxil Fumarate in Adolescents With Chronic Hepatitis B Infection
The primary purpose of the study is to evaluate the effectiveness, safety, and tolerability of tenofovir disoproxil fumarate (TDF) in adolescents (aged 12-17 years) with chronic hepatitis B virus (HBV) infection.
- Trial name
- NCT00734162
- Testing
- Tenofovir disoproxil fumarate (TDF)
- Where
- 21 sites in United States, Bulgaria and 5 more
- Volunteers
- 106 people
- Sponsor
- Gilead Sciences
Chronic Disease, Chronic Diseases in Adolescence
Home-based Aerobic Training Among Adolescents With Chronic Diseases During COVID-19 Pandemic
Data show that the coronavirus disease 2019 (COVID-19) symptoms can be severe in 4% and 3% of the adolescents aged 11-15 years and ≥ 16 years, respectively.
- Conditions
- Chronic Disease, Chronic Diseases in Adolescence, Chronic Disease of Immune System, Chronic Kidney Diseases
- Trial name
- NCT04458246
- Testing
- Exercise training group
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- University of Sao Paulo
Pruritus, Chronic Kidney Diseases
Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus
Rationale: People with long term kidney disease who are on haemodialysis (a procedure for removing waste products from the blood) commonly develop a condition that makes their skin very itchy.
- Trial name
- NCT06593392
- Testing
- Difelikefalin
- Where
- 18 sites in China, Greece and 5 more
- Volunteers
- 18 people
- Sponsor
- Vifor Fresenius Medical Care Renal Pharma
Chronic Hepatitis B
Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection
The goals of this clinical study are to compare the effectiveness, safety and tolerability of study drug, tenofovir alafenamide (TAF), versus placebo in teens and children with CHB and to learn more about the dosing levels in…
- Trial name
- NCT02932150
- Testing
- TAF
- Where
- 39 sites in United States, Belgium and 6 more
- Volunteers
- 150 people
- Sponsor
- Gilead Sciences
Chronic Kidney Failure, Congenital Heart Defects
Chronic Kidney Disease in Teenagers With Congenital Cardiac Disease
The prevalence of chronic kidney injury (CKD) following cardiac surgery during childhood is not known, but there is evidence of CKD in young adults.
- Trial name
- PRECARDIO (NCT01845402)
- Testing
- blood and urine samples
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cerebral Palsy
Robotic Exoskeleton Gait Training in Adolescents With Cerebral Palsy
The study design will consist of a cohort of adolescents and young adults with cerebral palsy (CP) that will undergo a gait training protocol.
- Trial name
- NCT05158218
- Testing
- Robotic Exoskeleton Gait Therapy, Physical Therapy
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Anxiety, Depression
Feasibility Testing a Meditation App for Professionals Working With Youth in the Legal System
This feasibility clinical trial aims to assess the feasibility of implementing a 1-month app-based meditation program with officers in the juvenile legal system and other professionals working directly with legal-involved youth.
- Conditions
- Anxiety, Depression, Burnout, Professional, Emotion Regulation
- Trial name
- NCT06555172
- Testing
- Action In Mindfulness (AIM)+, Resource+
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Cerebral Palsy (CP)
Intensive Rehabilitation Program for Upper Limb in Children and Adolescents With Cerebral Palsy
Cerebral palsy is the most common motor disability in children. Individuals with CP often experience significant difficulties in the use of their upper limbs, which affects their autonomy and quality of life.
- Trial name
- NCT07285837
- Testing
- Intensive Rehabilitation
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Fondation Ellen Poidatz
Cerebral Palsy
The Effects of Protocolized Breathing Exercises on Pulmonary Function in Adolescents With Cerebral Palsy.
This multicenter randomized controlled pilot trial evaluates whether an 8-week protocolized breathing exercise program improves pulmonary function and quality of life in adolescents and young adults with cerebral palsy.
- Trial name
- NCT07873593
- Testing
- Protocolized breathing exercises
- Where
- Hungary
- Volunteers
- 360 people
- Sponsor
- Semmelweis University
Congestive Heart Failure
Study to Evaluate the Safety of Twice Daily Oral Carvedilol
The objective of this study is to evaluate the long-term safety of carvedilol in pediatric patients with chronic heart failure, who completed the Pediatric Carvedilol Study 321.
- Trial name
- NCT00129363
- Testing
- Carvedilol
- Where
- 17 sites in United States
- Volunteers
- 75 people
- Sponsor
- Shaddy, Robert, M.D.
Chronic Kidney Disease, Renal Anemia
A Study of Roxadustat to Treat Anemia in Children and Teenagers With Chronic Kidney Disease
Roxadustat is a licensed medicine to treat anemia in adults with chronic kidney disease (CKD). Anemia is a low level of red blood cells.
- Trial name
- NCT05970172
- Testing
- Roxadustat
- Where
- 47 sites in Belgium, Croatia and 17 more
- Volunteers
- 98 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Asthma in Children, Asthma Chronic
Asthma Ctrl SMART Trial
The primary objective is to examine the efficacy of an mHealth adherence intervention (Asthma Ctrl) on adherence to daily inhaled corticosteroids as measured by electronically monitored adherence in adolescents with asthma.
- Trial name
- NCT07512622
- Testing
- Asthma Ctrl, Asthma Ctrl+, Control
- Where
- 2 sites in United States
- Volunteers
- 389 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Diseases in Adolescence, Cardio Vascular Disease
Lifestyle Practices With Chronic Diseases Among Different Professionals
A qualitative study conducted in 2018 Exploring socio-cultural factors impacting adherence to type 2 diabetes therapy in rural Sargodha featured respondents who were primarily doctors, patients, and.
- Conditions
- Chronic Diseases in Adolescence, Cardio Vascular Disease, Diabetes Type 2
- Trial name
- NCT05865717
- Testing
- Quantitative sampling, Qualitative interviews
- Where
- Pakistan
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Health Services Academy, Islamabad, Pakistan
Epilepsy
An Open-Label, Safety and Tolerability Study of Chronic Intermittent Use of Diazepam Nasal Spray.
This study will assess long-term safety and tolerability of repeat dose diazepam nasal spray in adolescents and adults with cluster seizures, with a focus on potential local effects (changes in nasal mucosa, olfaction, and taste).
- Trial name
- NCT02316847
- Testing
- diazepam nasal spray
- Where
- 33 sites in United States
- Volunteers
- 126 people
- Sponsor
- Acorda Therapeutics
Chronic Illness
Parents in Transition - a Nurse-led Support and Transfer Education Program
OBJECTIVE To improve chronically ill adolescents' transition to adult care by preparing and supporting the parents. The study aim is to improve parents' (of chronically ill adolescents, 16-18 years) transition readiness by…
- Trial name
- ParTNer-STEPs (NCT04969328)
- Testing
- ParTNer-STEPs
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Tourette Syndrome, Tourette Syndrome in Children
Tourette Discrimination (TD) Stigma Scale
The goal of this qualitative study is to understand the challenges of stigmatization and discrimination in children and young adults with Chronic Tic Disorders (CTD), including Tourette Syndrome.
- Conditions
- Tourette Syndrome, Tourette Syndrome in Children, Tourette Syndrome in Adolescence, Tic Disorder, Childhood
- Trial name
- TD (NCT05696769)
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Wake Forest University Health Sciences
Autoimmune Hepatitis, Primary Sclerosing Cholangitis
A-LiNK: Improving Outcomes in Autoimmune Liver Disease
The Autoimmune Liver disease Network for Kids (A-LiNK) is a multi-institutional group with the mission to deliver the best care to kids with pediatric autoimmune liver disease (AILD).
- Trial name
- ALINK (NCT05750498)
- Testing
- No interventions
- Where
- 8 sites in United States
- Volunteers
- 800 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Fatigue Syndrome
Efficacy of Web-based Cognitive Behavioural Treatment for Adolescents With Chronic Fatigue Syndrome
The aim of this study is to determine the efficacy of FITNET (web-based cognitive behavioural treatment) for adolescents with Chronic Fatigue Syndrome (CFS) in The Netherlands.
- Trial name
- FitNet (NCT00893438)
- Testing
- FitNet treatment, Usual care
- Where
- 2 sites in Netherlands
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht