Clinical trials: Chronic Diseases in Children
Child, Only, Chronic Diseases in Children
Effects of Colour-By-Number Mandalas ın Children Hospitalised Due to A Chronic Disease
Purpose: This study was conducted to find out the effects of colour by number mandala in decreasing the stress of hospitalized children with chronic disease. Design: A randomized controlled study.
- Trial name
- NCT05524272
- Testing
- This study aims to evaluate the effects of colour by number mandala in decreasing the stress of children hospitalized due to their chronic disease.
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Firat University
Cerebral Palsy
Loaded Gait Training on Gross Motor Function in Cerebral Palsy
A randomized controlled trial aimed to evaluate the additional effect loaded gait training to conventional physical therapy program on gross motor function and the knee extensors strength in children with bilateral spastic…
- Trial name
- NCT06339099
- Testing
- Conventional physical therapy program, Loaded gait training
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Spastic Diplegia Cerebral Palsy
Comparative Effects of Under Water Exercise and Radial Extracorporeal Shockwave Therapy on Lower-Limb Spasticity, Gross Motor Function, and Quality of Life in Children With Spastic Diplegic Cerebral Palsy: A Randomized Controlled Trial
Children with spastic diplegic cerebral palsy often present with lower-limb spasticity, limited gross motor function, and reduced quality of life.
- Trial name
- spastic CP (NCT07878949)
- Testing
- Group A, Group B
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Emad Eldin Mohamed
Leukemia
Chemotherapy in Treating Children With Relapsed Acute Leukemia, Acute Myeloid Leukemia, or Blastic Phase Chronic Myelogenous Leukemia
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of topotecan in treating children who have relapsed acute…
- Trial name
- NCT00003735
- Testing
- topotecan hydrochloride
- Where
- 38 sites in United States, Australia and 1 more
- Volunteers
- 11 people
- Sponsor
- Children's Oncology Group
Cerebral Palsy, Spastic
Effect of Motor Imagery Training on Gait and Balance in Children With Spastic Hemiplegia
This study aims to: Investigate the effect of motor imagery training on gait kinematics in children with spastic hemiplegia. Determine the effect of motor imagery training on balance in children with spastic hemiplegia.
- Trial name
- NCT04765917
- Testing
- Selected physical Therapy program, Motor imagery training program
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Scoliosis, Kyphosis
Postoperative and Chronic Pain Genetic Spine and Pectus Surgery Study
This will be an open label, prospective study to determine the association between specific genotypes, epigenetics and behavioral factors, with the phenotypes, defined by pain perception, postoperative pain, analgesic and side…
- Conditions
- Scoliosis, Kyphosis, Kyphoscoliosis, Pectus Excavatum
- Trial name
- NCT02998138
- Where
- 5 sites in United States
- Volunteers
- 880 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cerebral Palsy
BRAIN GYM EXERCISES and CEREBRAL PALSY
Brain gym is a series of exercises developed to enhance learning by improving cognitive function and fostering a stronger mind-body connection. It uses physical and mental techniques to stimulate both hemispheres of the brain.
- Trial name
- NCT07176858
- Testing
- brain gym exercise, specially designed pt program
- Volunteers
- 60 people
- Sponsor
- Cairo University
Growth Hormone Disorder, Growth Hormone Deficiency in Children
Observational Prospective Study on Patients Treated With Norditropin®
This observational study is conducted globally. The aim of the study is to investigate the effectiveness and safety of real-life treatment with Norditropin®.
- Conditions
- Growth Hormone Disorder, Growth Hormone Deficiency in Children, Adult Growth Hormone Deficiency, Genetic Disorder
- Trial name
- NCT00960128
- Testing
- somatropin
- Where
- 23 sites in Argentina, Belgium and 21 more
- Volunteers
- 21,249 people
- Sponsor
- Novo Nordisk A/S
Asthma
Efficacy Study of the Product "CHF 1535" Versus Beclomethasone (BDP) and Free Combo in Asthmatic Children
The purpose of this study is to demonstrate that CHF 1535 in pressurized metered dose inhaler (pMDI) is non-inferior to the corresponding dose of free combination of Beclomethasone (BDP) and Formoterol Fumarate (FF) and superior…
- Trial name
- PAED2/FRESH (NCT01475032)
- Testing
- CHF 1535, Beclomethasone (BDP), Beclomethasone (BDP) + Formoterol Fumarate (FF)
- Where
- 11 sites in Bulgaria, France and 9 more
- Volunteers
- 638 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Cerebral Palsy
Mirror Therapy With Sensory Motor Training in Children With CP
The study compares two interventions in CP children: mirror therapy with sensory motor training versus mirror therapy with motor training.
- Trial name
- NCT06292416
- Testing
- Experimental: Mirror therapy with sensory motor training., Experimental: Mirror Therapy with motor training, Experimental: Motor Training
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Chronic Hepatitis C, Decompensated Cirrhosis
A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With Ribavirin in Adults With Genotype 1 and Ombitasvir/Paritaprevir/Ritonavir With Ribavirin in Adults With Genotype 4 Chronic Hepatitis C Virus Infection and Decompensated Cirrhosis
The primary objectives of this study are to assess the safety and the SVR12 rate of ombitasvir/paritaprevir/ritonavir and dasabuvir with RBV in GT1-infected participants with decompensated cirrhosis.
- Conditions
- Chronic Hepatitis C, Decompensated Cirrhosis, Hepatitis C Virus
- Trial name
- TURQUOISE-CPB (NCT02219477)
- Testing
- ombitasvir/paritaprevir/ritonavir, dasabuvir, ribavirin
- Volunteers
- 36 people
- Sponsor
- AbbVie
Primary Headache Disorder
Feasibility of a Developmentally-tailored Mobile App for Tracking Mood and Pain in Children With Migraine
This study aims to inform the continued development of a mobile app intended to support the treatment of CYP with migraine. After extensive public and patient involvement, Happyr Health has developed a mobile app that allows…
- Trial name
- NCT05337930
- Testing
- Happyr App
- Where
- United Kingdom
- Sponsor
- Happyr Ltd
Overweight in Preschool Age Children, Risk of Overweight in Preschool Age Children
Improving Primary Care to Prevent Childhood Obesity
To determine the extent to which a clinical intervention based on the Chronic Care Model (CCM), compared with the usual care control condition, results in a smaller age-associated increase in body mass index (BMI) over a 1 year…
- Trial name
- NCT00377767
- Testing
- To change structure and roles of primary care teams to optimize prevention of obesity
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hepatitis C Virus Infection
Study to Investigate the Safety and Efficacy of Sofosbuvir/Velpatasvir in Adolescents and Children With Chronic HCV Infection
This study will have 2 parts: Pharmacokinetics (PK) Lead-in Phase and the Treatment Phase. The primary objective of the PK Lead-in Phase is to evaluate the steady state PK and confirm the dose of sofosbuvir/velpatasvir (SOF/VEL)…
- Trial name
- NCT03022981
- Testing
- SOF/VEL
- Where
- 27 sites in United States, Belgium and 2 more
- Volunteers
- 216 people
- Sponsor
- Gilead Sciences
Cerebral Palsy
Effectiveness Ankle-7 Orthosis VS HAFO Orthosis on Gait in Diplegic CPChildren
Ankle foot orthoses (AFO) are frequently used to improve locomotor skills of cerebral palsied children (CP) although the level of scientific evidence to support their use is still moderate.
- Trial name
- NCT03333434
- Testing
- Carbon Ankle Seven spring (A7 - Otto Bock, Germany), Hinged AFO
- Volunteers
- 10 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Chronic Kidney Disease, Hypertension
Arterial Stiffness in Children and Young People With Hypertension and Chronic Kidney Disease
Age related stiffening and hardening of the arteries is often a slow process, but some conditions such as chronic kidney disease (CKD), seem to increase the rate at which the arteries stiffen even during childhood.
- Trial name
- ART-KIDS (NCT07768865)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- King's College London
Spastic Diplegia, Motor Imagery
Effect of Multisensory Motor Imagery Training on Muscle Performance and Coordination in Children With Spastic Diplegia
PURPOSE: The current study aims to: Determine the effect of multisensory motor imagery training on muscle performance including (peak torque, work, power) of trunk and knee flexors and extensors in children with spastic diplegia.
- Trial name
- NCT06676332
- Testing
- motor imagery training, traditional physical therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Chronic Kidney Disease 5D, Chronic Kidney Disease 5T
Humoral and Cellular İmmune Response to SARS-CoV-2 mRNA BNT162b2 Vaccine in Children With Chronic Kidney Diseases
Coronavirus 2019 (COVID-19) infection is associated with higher morbidity and mortality in adult patients on dialysis, and kidney transplant recipients (KTRs).
- Trial name
- NCT05465863
- Testing
- SARS-CoV-2 mRNA BNT162b2 vaccine (Pfizer-BioNTech®)
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Cerebral Palsy
Effect of Nordic Walking on Gait-asymmetry Patterns in Children With Hemiparesis
Nordic walking is a physical activity consisting of walking with poles similar to ski poles. The poles are designed for the purpose of activating the upper body during walking.
- Trial name
- NCT05644652
- Testing
- designed physical therapy program, Nordic walking
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Chronic Lung Disease
Surfactant Disorders and Chronic Lung Disease
Interstitial lung diseases (ILD) in children represent a heterogeneous group of rare and not well defined disorders. Genetic abnormalities of surfactant proteins B (SFTPB) and more recently C (SFTPC) have been shown to be related…
- Trial name
- APSE (NCT00783978)
- Testing
- whole blood sample
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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