Clinical trials: Chronic End Stage Renal Failure
Anemia, Chronic Kidney Diseases
Effect of rEPO in FGF23 in ESRD Patients
Objective: To evaluate the effects of recombinant Erythropoietin (rEPO) in plasma levels of Fibroblast Growth Factor 23 (FGF23) in End-Stage Renal Disease (ESRD) patients in hemodialysis.
- Trial name
- NCT03803514
- Testing
- Recombinant EPO
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University of Chile
End Stage Renal Disease (ESRD)
Effect of Medium Cut-Off Hemodialysis on Protein Energy Wasting: The EMCOPEW Study
In patients on maintenance hemodialysis (HD), protein energy wasting (PEW) defined as loss of muscle mass and fuel reserves of the body is frequent and associated with severe morbidity and mortality.
- Trial name
- EMCOPEW (NCT05309109)
- Testing
- Hemodialysis sessions
- Where
- 2 sites in France
- Volunteers
- 65 people
- Sponsor
- Poitiers University Hospital
Chronic Hepatitis C, End Stage Renal Disease
Interferon Treatment for Patients With Chronic Hepatitis C and End Stage Renal Disease
The treatment response with conventional interferon alpha alone in patients with end stage renal disease and chronic hepatitis C is about 33-39%. However, the drop-out rate is 17-29.6%.
- Trial name
- NCT00172809
- Testing
- Peginterferon alfa-2a, Interferon alfa-2a
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
End Stage Renal Disease, Chronic Kidney Diseases
Ferric Citrate in ESRD Pilot Project
This research study is for participants that have End Stage Renal Disease (ESRD). ESRD is the last stage of chronic kidney disease.
- Trial name
- NCT03055598
- Testing
- Ferric Citrate
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Sreedhar Mandayam
End Stage Renal Disease, Hypertension
Blood Pressure Slopes and Ultrafiltration in Hemodialysis Patients
Kidney failure has been recognized as one of the most costly chronic conditions among United States Veterans. Approximately 13,000 Veterans develop kidney failure each year, and most require hemodialysis initiation.
- Conditions
- End Stage Renal Disease, Hypertension, Extracellular Volume Overload, Intradialytic Hypotension
- Trial name
- NCT04163614
- Testing
- IBPS-Guided Ultrafiltration
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- VA Office of Research and Development
End Stage Renal Disease, Inflammation
Evaluation of Biocompatibility and Performances of 4 Dialyzers in Different Mode Treatments
Prospective multicenter randomized cross-over study Number of patients : 32 (8 patients per group) Obtain objectives data to advise each hemodialyzer according to dialysis treatment and patient profile.
- Trial name
- BIOMODAL (NCT03262272)
- Testing
- VIE A Hemodialyzer, Rexsys 27H hemodialyzer, Leoceed 21HX hemodialyzer
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Hemotech
End Stage Renal Disease
Central Blood Pressure and Pulse Wave Velocity in Kidney Transplant Recipients
An observational cohort study will be conducted to non-invasively investigate central blood pressure and pulse wave velocity in children with kidney disease and controls.
- Trial name
- NCT04212143
- Testing
- there is no intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's National Research Institute
Cardiovascular Disease, End Stage Renal Disease
Safety and Tolerability of Coenzyme Q10 in Hemodialysis Patients
The purpose of this study is to determine the safety and tolerability of the dietary supplement Coenzyme Q10 in hemodialysis patients.
- Conditions
- Cardiovascular Disease, End Stage Renal Disease, Atherosclerosis, Oxidative Stress
- Trial name
- NCT00908297
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Chronic Renal Failure
Phase Ⅳ Clinical Trial to Evaluate of Renamezin in Patients With Chronic Renal Failure.
Renamezin Capsule (an oral adsorbent) lowers indoxyl sulfate levels in patient with chronic renal failure. 120 patients with chronic renal failure(baseline serum creatinine:1.5-5.0mg/dl). Renamezin is administered 6.0mg/day.
- Trial name
- NCT02681991
- Testing
- Renamezin capsule
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Fluid Accumulation, Blood Pressure Management
Dry Weight Reduction Intervention Via Extra Ultrafiltration
Most patients who receive hemodialysis treatments have excess fluid in their body that has slowly built up over the course of kidney disease.
- Conditions
- Fluid Accumulation, Blood Pressure Management, End Stage Renal Disease (ESRD)
- Trial name
- DRIVE-UF (NCT07637110)
- Testing
- Ultrafiltration
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Washington
End Stage Renal Disease
Quality of Life on Peritoneal Dialysis Versus Hemodialysis in China
This is a multicenter, randomized, open-label study to compare QoL in subjects with end-stage renal disease (ESRD) requiring PD or conventional in-center HD treatment.
- Trial name
- NCT02378350
- Testing
- Hemodialysis treatment (no specific device is defined), Peritoneal Dialysis treatment (no specific drug is defined)
- Where
- 21 sites in China
- Volunteers
- 668 people
- Sponsor
- Vantive Health LLC
End Stage Renal Failure
Registry for End Stage Renal Failure
The rein registry collects case record data from patients with end stage renal disease followed in French Guiana. This allows to generate incidence and rates for terminal renal disease, mortality rates for each territory.
- Trial name
- REIN (NCT02895425)
- Testing
- Registry (No intervention)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier de Cayenne
Chronic Renal Failure, Renal Insufficiency, Chronic
Highlighting the Medico-economic Interest of an Adapted Physical Activity for Haemodialysis Patients
Chronic hemodialysis is often associated with a reduction in the quality of life of patients and a reduction in physical activity, due to the repeated frequency of sessions.
- Trial name
- NEPHRACTIVE (NCT04399655)
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Clinique Néphrologique Saint-Exupéry
Myocardial Stunning, End-stage Renal Disease
Myocardial Stunning During Hemodialysis: Role of Dialyste Calcium Concentration
Chronic kidney disease (CKD) is linked to elevated mortality rate, and cardiovascular disease is the main cause related to this outcome.
- Trial name
- NCT02545426
- Testing
- Change the dialysate calcium concentration
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- University of Sao Paulo General Hospital
Hypercholesterolemia, Chronic Nephropathy
Ezetimibe/Simvastatin Combination in Proteinuric Nephropathy
The purpose of this study is to determine whether, in patients with chronic proteinuric nephropathy and dyslipidemia, ezetimibe-simvastatin combined therapy is more effective than statin alone to achieve the optimum lipid…
- Trial name
- VICTORY (NCT00861731)
- Testing
- simvastatin, EZE/simvastatin
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Azienda Ospedaliero Universitaria di Sassari
Renal Transplant Rejection, Pediatric Kidney Disease
VIRTUUS Children's Study
The objective of the VIRTUUS Children's Study is to adapt identified and validated adult noninvasive diagnostic and prognostic biomarkers for the characterization of allograft status in pediatric recipients of kidney allografts.
- Conditions
- Renal Transplant Rejection, Pediatric Kidney Disease, End Stage Renal Disease, Nephropathy
- Trial name
- VIRTUUS (NCT03719339)
- Where
- 13 sites in United States, Canada
- Volunteers
- 445 people
- Sponsor
- Children's Hospital of Philadelphia
Uremic Pruritus
Treatment of Uremic Pruritus With PA101B
This is a randomized, double blind, placebo-controlled, parallel-arm, multi-center, Phase 2, proof-of-concept efficacy and safety study in patients with end-stage renal disease requiring hemodialysis.
- Trial name
- NCT02696499
- Testing
- PA101B
- Where
- 13 sites in United States
- Volunteers
- 70 people
- Sponsor
- Patara Pharma
End Stage Renal Failure, Hemodialysis, Fatigue
Reflexology Versus Progressive Muscle Relaxation for Fatigue in Hemodialysis Patients
The goal of this clinical trial is to compare the effects of reflexology and progressive muscle relaxation in reducing fatigue among hemodialysis patients and to determine which intervention provides greater relief from fatigue.
- Trial name
- PMR-HD (NCT07575607)
- Testing
- reflexology, progressive muscle relaxation, Control
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
End Stage Renal Disease / Hemodialysis
Mineralocorticoid Receptor Antagonists in End Stage Renal Disease
End stage renal disease (ESRD) patients exhibit an extraordinarily high annual mortality. Cardiovascular (CV) causes account for almost half of all-cause mortality.
- Trial name
- MiREnDa (NCT01691053)
- Testing
- Spironolactone
- Where
- 3 sites in Germany
- Volunteers
- 118 people
- Sponsor
- Wuerzburg University Hospital
type1diabetes, Renal Failure
Kidney Alone Versus Islet-After-Kidney in Type 1 Diabetic Kidney Transplant Recipient.
Islet transplantation is associated with a benefit on glycaemic control compared to optimized insulin therapy in recent clinical trials.
- Conditions
- type1diabetes, Renal Failure, End Stage Renal Disease
- Trial name
- KA-IAK (NCT05662267)
- Testing
- Pancreatic islet transplantation after kidney transplantation
- Where
- France
- Volunteers
- 327 people
- Sponsor
- University Hospital, Lille
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.