Clinical trials: Chronic Fatigue Symptoms
Progressive Multiple Sclerosis
Study of Circadian Focused Light Therapy in Progressive Multiple Sclerosis
The study is being done to determine if treatment with a novel form of light therapy is tolerated in patients with progressive multiple sclerosis.
- Trial name
- NO-FATIGUE (NCT06261528)
- Testing
- Light therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Fatigue Syndrome, Chronic
Fatigue in Air Search and Rescue Missions
The purpose of this observational study is to understand and evaluate the physiological, psychological, and cognitive impact of 15 consecutive days of air search and rescue mission deployments on Portuguese Air Force crews.
- Trial name
- NCT06253026
- Testing
- Search and rescue mission
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Advanced Cancers, Solid Tumors
The Effects of Ginseng on Cancer-Related Fatigue
The goal of this clinical research study is to learn if panax ginseng (commonly called ginseng) can help to control fatigue and other symptoms such as depression, anxiety, and mood changes in patients with cancer.
- Trial name
- NCT01375114
- Testing
- Panax Ginseng, Questionnaires
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- M.D. Anderson Cancer Center
Chronic Fatigue Syndrome
Biofeedback and Hydrogen Water as Treatments for Chronic Fatigue Syndrome
The aim of this 10-week pilot study is to explore the potential benefit of two recently developed non-invasive interventions, heart rate variability biofeedback (HRV-BF) and OTC supplement hydrogen water, for the symptoms of…
- Trial name
- NCT05397626
- Testing
- Heart Rhythm Biofeedback, Hydrogen Water, Combined treatment: Heart rhythm biofeedback plus hydrogen water
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Stony Brook University
Breast Neoplasms, Musculoskeletal Pain
Multicomponent Care for Aromatase Inhibitor-Related Musculoskeletal Symptoms
Breast cancer patients who receive endocrine therapy particularly aromatase inhibitors often experience aromatase inhibitors associated symptoms (AIMSS) such as joint and muscle pain along with stiffness and fatigue that can…
- Conditions
- Breast Neoplasms, Musculoskeletal Pain, Arthralgia, Musculoskeletal Diseases
- Trial name
- AIMSS-CARE (NCT07409948)
- Testing
- Multicomponent Care for Aromatase Inhibitor-Related Musculoskeletal Symptoms (AIMSS-CARE)
- Volunteers
- 88 people
- Sponsor
- Addis Ababa University
Long COVID, Post-COVID-19 Condition
A Study of Human Umbilical Cord Blood (REGENECYTE) Infusion in Patients With Post-COVID Condition
REGENECYTE (HPC, Cord Blood) for treatment in patients with post-COVID.
- Conditions
- Long COVID, Post-COVID-19 Condition, Post-COVID Syndrome, Post-COVID Condition
- Trial name
- NCT07184385
- Testing
- REGENECYTE
- Volunteers
- 60 people
- Sponsor
- StemCyte, Inc.
Chronic Obstructive Pulmonary Disease, Foot Deformities
The Effect of Foot Deformities on Physical Activity, Fatigue Level and Quality of Life in Elderly COPD Patients
The aim of this study is to investigate the effects of changes in foot structure on physical activity level, fatigue and quality of life in COPD patients.
- Conditions
- Chronic Obstructive Pulmonary Disease, Foot Deformities, Quality of Life, Activity, Motor
- Trial name
- NCT04627935
- Testing
- The COPD Assessment Test, Navicular Drop Test, International Physical Activity Questionnaires (IPAQ)
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Irritable Bowel Syndrome, Inflammatory Bowel Disease
25-hydroxyvitamin D and Fatigue: The VITALITY Study
The burden of chronic disease is continuing to rise. Even though patients may be in remission or have quiescent disease, several studies have confirmed that symptoms, such as e.g., fatigue, is troublesome.
- Conditions
- Irritable Bowel Syndrome, Inflammatory Bowel Disease, Diabetes, Rheumatoid Arthritis
- Trial name
- NCT01718925
- Volunteers
- 614 people
- Sponsor
- Ostfold Hospital Trust
Cancer Related Fatigue
REBECCA-3 Study, Research on Breast Cancer Induced Chronic Conditions Supported by Causal Analysis of Multi-source Data
The overall aim of the REBECCA project is to exploit the potential of "real-world data" to support clinical research and improve existing clinical workflow.
- Trial name
- REBECCA-3 (NCT06435091)
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Helse Stavanger HF
Chronic Fatigue Syndrome
Effectiveness of VIRTUAL SFCAMINA STUDY
The main objective of this study is to analyse the effectiveness of the VIRTUAL SFCAMINA multicomponent treatment program as coadjuvant of treatmentas- usual (TAU) compared to TAU alone.
- Trial name
- SFCAMINA (NCT04593225)
- Testing
- TAU + multicomponent treatment VIRTUAL SFCAMINA, Treatment as Usual (TAU)
- Where
- 2 sites in Spain
- Volunteers
- 480 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Chronic Pain
Development of a Computerized Adaptive Test (CAT) for Evaluation of Sleep, Fatigue and Quality of Life in Patients With Chronic Pain
The purpose of this study is to evaluate quality of life, sleep and fadigue in patients with chronic pain using an Item-Response Theory methodology and also generating a Computer Adaptive Testing System
- Trial name
- CAT (NCT03410589)
- Testing
- Sinlge arm
- Where
- Brazil
- Volunteers
- 308 people
- Sponsor
- University of Sao Paulo
Chronic Immune Thrombocytopenia, Primary Immune Thrombocytopenia
Cognitive Status, Fatigue and Inflammation in Patients With Immune Thrombocytopenia (ITP)
This is a multi-center, hospital based, cross-sectional study based on data from patient medical records, including laboratory results.
- Conditions
- Chronic Immune Thrombocytopenia, Primary Immune Thrombocytopenia, Adult Immune Thrombocytopenia
- Trial name
- NCT06665308
- Testing
- No intervention
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 97 people
- Sponsor
- Sanofi
Long-COVID, Post-acute COVID-19 Syndrome
Effectiveness of Non-invasive Neuromodulation in Patients With Long-COVID
Sleep quality and duration are critical to cognitive, emotional and physical well-being, and poor sleep quality has been associated with an increased risk of cognitive, psychological and cardiometabolic disorders.
- Trial name
- NCT06456502
- Testing
- Non-invasive neuromodulation
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Universidad Rey Juan Carlos
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Assessment of N-Acetylcysteine as Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Chronic fatigue syndrome/myalgic encephalomyelitis (ME/CFS) is an unexplained multisymptom/multisystem disorder for which there are currently no validated treatments.
- Trial name
- NAC ME/CFS (NCT04542161)
- Testing
- NAC 900mg/day, NAC 3600mg/day
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Weill Medical College of Cornell University
Chronic Fatigue Syndrome, Fibromyalgia
Central Mechanisms of Chronic Pain and Fatigue Subtitle: Functional Imaging of Brain and Spinal Cord
Chronic pain and fatigue are characterized by peripheral and central mechanisms including low pain thresholds, temporal summation, peripheral and central sensitization.
- Trial name
- NCT03075254
- Testing
- A Peltier for Sensory testing, functional magnetic resonance imaging for Brain Neuroimaging, fMRI for Spinal Cord Neuroimaging
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of Florida
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Tumor Necrosis Factor-alpha Inhibition Using Etanercept in Chronic Fatigue Syndrome
The hypothesis is that a subset of patients with chronic fatigue syndrome/ myalgic encephalomyelitis (CFS/ME), including also patients with no clinical response after B-cell depletion therapy using the anti-CD20 antibody…
- Trial name
- NCT01730495
- Testing
- Etanercept
- Where
- Norway
- Volunteers
- 4 people
- Sponsor
- Haukeland University Hospital
Chronic Ankle Instability, CAI
Effects of Rigid and Kinesio Taping on Balance and Performance in Chronic Ankle Instability
The goal of this clinical trial is to evaluate the immediate effects of rigid subtalar sling taping, kinesio subtalar sling taping, and sham taping on balance, proprioception, ankle mobility, and functional performance in…
- Trial name
- FAST-CAI (NCT07627165)
- Testing
- Rigid Subtalar Sling Taping, Kinesio Subtalar Sling Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul Nisantasi University
Long COVID
The Impact of Chiropractic on Long COVID-19
The purpose of this waitlist-controlled, single-blind, one-way crossover, pilot trial is to evaluate the potential effects of ~8 weeks of chiropractic care on patient-reported fatigue and the autonomic nervous system in adults…
- Trial name
- NCT05693064
- Testing
- wait-list, chiropractic adjustments
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Life University
COPD, Mediation
Effects of Progressive Muscle Relaxation and Mindfulness Meditation in Patients With Chronic Obstructive Pulmonary Disease
Patients with COPD will be entered. Participants will be randomized to one of three study arms: Arm 1: meditation; Arm 2: relaxation; Arm 3: Control.
- Conditions
- COPD, Mediation, Fatigue, Symptoms and Signs
- Trial name
- NCT04301700
- Testing
- mindfullness and relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Hacettepe University
SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis
Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center?
The primary objective of the present research is to determine the effectiveness of Family Health Center of San Diego's Long COVID and Fatiguing Illness Recovery Program (LC\&FIRP) on clinician- and patient-level outcomes.
- Conditions
- SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, Post-acute Sequelae of SARS-COV-2 Infection
- Trial name
- LC&FIRP (NCT05167227)
- Testing
- Extension for Community Healthcare Outcomes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Family Health Centers of San Diego