Clinical trials: Chronic Fatigue Symptoms
Long COVID, Post-COVID19 Condition
Amantadine Therapy for Cognitive Impairment in Long COVID
This study will look at the effects of amantadine on cognitive function in persons with Long COVID. It will also collect specimens to study possible causes of cognitive symptoms in Long COVID, and whether any lab tests can…
- Conditions
- Long COVID, Post-COVID19 Condition, Post-Acute COVID19 Syndrome
- Trial name
- AmantadineLC (NCT06055244)
- Testing
- Amantadine
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Ohio State University
Pulmonary Disease, Chronic Obstructive
The Effect of Respiratory Training on Exercise Tolerance in COPD
Exercise intolerance is one of the key disabling factors in patients with chronic obstructive pulmonary disease (COPD). Although multifactorial, exercise intolerance involves physiological interactions between respiratory and…
- Trial name
- ERTET (NCT04201522)
- Testing
- Normocapnic hyperpnoea intervention
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Cancer Related Fatigue
Intervention Study Based on Real-world Data to Improve Quality of Life After Breast Cancer Treatment, the REBECCA-2 Study
The overall objective of the REBECCA studies at Stavanger University Hospital (SUH) is to improve the QoL of patients affected by cancer-related fatigue during and after end of treatment, by collecting multi-source real world…
- Trial name
- NCT06120595
- Testing
- REBECCA-assisted intervention 1, REBECCA-assisted intervention 2, Standard follow-up
- Where
- Norway
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Chronic Lymphocytic Leukemia
Ruxolitinib Phosphate in Reducing Fatigue in Patients With Chronic Lymphocytic Leukemia
This phase II trial studies how well ruxolitinib phosphate works in reducing fatigue in patients with chronic lymphocytic leukemia.
- Trial name
- NCT02131584
- Testing
- Questionnaire Administration, Ruxolitinib Phosphate
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- M.D. Anderson Cancer Center
Cardiac Failure, Heart Failure
Insomnia Self-Management in Heart Failure
Chronic insomnia may contribute to the development and exacerbation of heart failure (HF), incident mortality and contributes to common and disabling symptoms (fatigue, dyspnea, anxiety, depression, excessive daytime sleepiness…
- Conditions
- Cardiac Failure, Heart Failure, Congestive Heart Failure, Heart Failure, Congestive
- Trial name
- HSS (NCT02660385)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Self-Management Education for Heart Failure
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Yale University
Fibromyalgia, Chronic Pain
The Effectiveness of Operant Learning Versus Energy Conservation Activity Pacing Treatments in Fibromyalgia
Activity pacing (AP) is a commonly used treatment for people with chronic pain. Many people with pain try to continue their daily activities at the same level as they were able to manage before they had pain.
- Trial name
- NCT01674335
- Testing
- Operant Learning, Energy Conservation
- Where
- Canada
- Volunteers
- 69 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Sleep Apnea, Obstructive, Hypertension
Epidemiology and Intervention of Obstructive Sleep Apnea Based on Community
This observational study in a real-world community was designed to perform epidemiological investigation and assess effect of CPAP intervention of obstructive sleep apnea.
- Conditions
- Sleep Apnea, Obstructive, Hypertension, Obesity, Diabetes
- Trial name
- NCT03280914
- Testing
- Auto-CPAP
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Guangdong Provincial People's Hospital
Chronic Fatigue Syndrome (CFS)
MicroRNAs as Biomarkers of Pain Intensity in Patients With Chronic Fatigue Syndrome (CFS)
MicroRNAs were shown to play an important role in regulating pain-processing in a wide range of experimental models and clinical pain disorders.
- Trial name
- CFs (NCT03892954)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- King Saud University
Anxiety Disorder, Cancer Survivor
Quality of Life in Younger Leukemia and Lymphoma Survivors
RATIONALE: Collecting information about the effect of hematologic cancer and its treatment on quality of life may help doctors learn more about the disease and plan the best treatment.
- Conditions
- Anxiety Disorder, Cancer Survivor, Fatigue, Leukemia
- Trial name
- NCT00956475
- Testing
- telephone-based intervention, questionnaire administration, assessment of therapy complications
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Case Comprehensive Cancer Center
Chronic Heart Failure
Tai Chi Training for Elderly People With Chronic Heart Failure
Physical activity is recommended in the treatment of heart failure. Elderly people demand various forms of physical activity. Tai chi has shown to be an appreciated form of physical activity among elderly, although there is a…
- Trial name
- NCT01294111
- Testing
- Tai Chi training
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Umeå University
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Survey and Cognitive Behavior Therapy for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
The purpose of this study is to analyze income variables in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis, and to analyze the effect of short vs. long Cognitive Behaviour Therapy.
- Conditions
- Chronic Fatigue Syndrome, Myalgic Encephalomyelitis, Fatigue, Pain
- Trial name
- NCT00920777
- Testing
- CBT, Control group
- Where
- Norway
- Volunteers
- 234 people
- Sponsor
- Norwegian University of Science and Technology
Fibromyalgia (FM), Chronic Fatigue Syndrome (CFS)
Molecular Response to Custom Manual Physiotherapy Treatment of Fibromyalgia & Chronic Fatigue Syndrome (CFS)
Fibromyalgia (FM)and Chronic Fatigue Syndrome (CFS) are complex diseases often presenting overlapping symptomatology. Manual therapy (MT) protocols report benefits for pain treatment of FM, but the underlying mechanisms for…
- Trial name
- NCT04174300
- Testing
- Manual Therapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Obesity, Insulin Resistance
Lifestyle Intervention Targetting Obesity and Insulin Resistance in Chronic Hepatitis C
Chronic hepatitis C (CHC) infection affects approximately 1 in 100 Canadians. Untreated, CHC has significant long-term consequences including cirrhosis, liver cancer and liver failure.
- Conditions
- Obesity, Insulin Resistance, Metabolic Syndrome, Hepatitis C
- Trial name
- NCT00755742
- Testing
- Lifestyle intervention
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University Health Network, Toronto
Chronic Fatigue Syndrome
High-tech Acupuncture for Treatment of Chronic Fatigue Syndrome
1. To study the relationship between Chronic Fatigue Syndrome (CFS) and heart rate (HR) and its variability (HRV). 2. To compare the curative effects and the HR/HRV indices between applicationa of different acupoints as well as…
- Trial name
- NCT02924831
- Testing
- Acupuncture, moxibustion
- Where
- China
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibust
Chronic Fatigue Syndrome
Psychological Wellbeing in Chronic Fatigue Syndrome
Objectives: Chronic Fatigue Syndrome (CFS) is a medically unexplained condition characterized by severe and disabling fatigue. To date much research has focused on finding out whether CFS is caused by mainly physical or…
- Trial name
- NCT02094820
- Where
- 2 sites in United Kingdom
- Volunteers
- 61 people
- Sponsor
- Royal Holloway University
Fatigue
Acupuncture for the Treatment of Chronic Post-Chemotherapy Fatigue
This is a randomized, placebo controlled study in cancer patients reporting fatigue persisting for at least two months following completion of chemotherapy.
- Trial name
- NCT00658034
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Alta Bates Summit Medical Center
Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), Chronic Fatigue
Modafinil for Debilitating Fatigue in Quiescent Inflammatory Bowel Disease MODIFI-IBD Trial)
The goal of this clinical trial is to learn if modafinil can treat severe fatigue in adults aged 18 to 75 years with quiescent inflammatory bowel disease (IBD).
- Trial name
- MODIFI-IBD (NCT07582458)
- Testing
- Modafinil
- Where
- 2 sites in Netherlands
- Volunteers
- 60 people
- Sponsor
- Radboud University Medical Center
Chronic Obstructive Pulmonary Disease
Fatigue and Physical Performance During Pulmonary Rehabilitation
Patients with COPD benefit from pulmonary rehabilitation (PR), but a ceiling effect of performance (ie. absence of additional exercise tolerance increase) is observed in 80% of patients from only 20 sessions.
- Trial name
- PROMOD (NCT04279730)
- Where
- 3 sites in France
- Volunteers
- 96 people
- Sponsor
- 5 Santé
Multiple Sclerosis, Chronic Pain
MS Symptom Management Study
People with Multiple Sclerosis (MS) often have pain and/or fatigue. Unfortunately, available treatments provide inadequate relief for the majority of these individuals.
- Conditions
- Multiple Sclerosis, Chronic Pain, Fatigue
- Trial name
- ENHANCE (NCT02474940)
- Testing
- Intervention #1, Intervention #2, Intervention #3
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Washington
Anemia, Cancer Fatigue
Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia
This phase II trial studies the side effects of ex vivo-activated autologous lymph node lymphocytes infusion and to see how well they work in treating patients with chronic lymphocytic leukemia.
- Conditions
- Anemia, Cancer Fatigue, Chronic Lymphocytic Leukemia, Fever
- Trial name
- NCT02530515
- Testing
- Ex Vivo-activated Autologous Lymph Node Lymphocytes, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- M.D. Anderson Cancer Center