Clinical trials: Chronic Fatigue Symptoms
Chronic Fatigue Syndrome
Hydrogen Water Treatment for Chronic Fatigue Syndrome
The proposed placebo-controlled pilot study will examine hydrogen water as a treatment for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). 25 subjects who meet strict criteria for ME/CFS will be recruited.
- Trial name
- H2CFS (NCT05013606)
- Testing
- Hydrogen water
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Stony Brook University
Low Back Pain (LBP), Chronic Low Back Pain
Lumbar Support Belt for Low-Back Pain in Office Workers
Background: Low-back pain (LBP) is common among office workers and can reduce productivity and quality of life. Lumbar support belts are commonly used to manage LBP, but their effectiveness specifically for office workers remains…
- Conditions
- Low Back Pain (LBP), Chronic Low Back Pain, Non-specific Low Back Pain
- Trial name
- NCT07030816
- Testing
- Guardner Belt
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- General Incorporated Foundation Ryukyuseimeisaiseikai, Ryusei Hospital.
Chronic Fatigue Syndrome (CFS)
MicroRNAs as Biomarkers of Pain Intensity in Patients With Chronic Fatigue Syndrome (CFS)
MicroRNAs were shown to play an important role in regulating pain-processing in a wide range of experimental models and clinical pain disorders.
- Trial name
- CFs (NCT03892954)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- King Saud University
Progressive Multiple Sclerosis, Fatigue
A Study of Oxidative Pathways in MS Fatigue
This is a 4-week randomized, placebo-controlled, parallel group, double-blind, single center trial on effect of N-acetyl cysteine versus placebo on fatigue in patients with progressive MS defined by McDonald criteria.
- Trial name
- NCT02804594
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
ME/CFS, Post-COVID ME/CFS
Immunoadsorption in Patients With Chronic Fatigue Syndrome Including Patients With Post-COVID-19 CFS
The goal of this clinical trial is to learn about the effectiveness of repeated immunoadsorption intervention in patients with chronic fatigue syndrome (CFS) including patients with post-acute COVID-19 CFS (PACS-CFS).
- Trial name
- NCT05710770
- Testing
- Immunoadsorption
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- Charite University, Berlin, Germany
Liver Disease
The Physiology of Fatigue in Patients With Chronic Liver Disease
Background: Fatigue is a common and often disabling symptom in people with chronic liver disease. Its causes are not well understood.
- Trial name
- NCT01867385
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Fatigue Syndrome
Use of Xyrem to Improve Sleep in Chronic Fatigue Syndrome
Chronic fatigue syndrome is a disabling illness for which there is no specific treatment. As a group, CFS patients have disturbed sleep with frequent arousals and the sense of not having slept upon awakening.
- Trial name
- NCT00498485
- Testing
- Sodium Oxybate
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Multicausal Fatigue, Fatigue
Micro-choice-based Intervention for Multicausal Fatigue
This proof-of-concept study aims to evaluate the feasibility, acceptability, and potential benefits of a novel multimodal approach: the micro-choice-based intervention.
- Conditions
- Multicausal Fatigue, Fatigue, Post COVID Condition, Long COVID Syndrome
- Trial name
- CHOOSE-POC (NCT07726082)
- Testing
- Micro-choice-based intervention
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University Hospital, Basel, Switzerland
Chronic Fatigue Syndrome
Psychological Wellbeing in Chronic Fatigue Syndrome
Objectives: Chronic Fatigue Syndrome (CFS) is a medically unexplained condition characterized by severe and disabling fatigue. To date much research has focused on finding out whether CFS is caused by mainly physical or…
- Trial name
- NCT02094820
- Where
- 2 sites in United Kingdom
- Volunteers
- 61 people
- Sponsor
- Royal Holloway University
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Chronic Infections and Inflammation in ME/CFS: An Observational Study
CHIIME is a study of people who have myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). People who do not have this condition will also be enrolled.
- Trial name
- CHIIME (NCT07227441)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Fatigue Syndrome, Chronic
Epigenetics of Post-exertional Malaise in Patients With ME/CFS
Exploring epigenetic mechanisms of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) is crucial to understand the mechanisms underlying its pathophysiology.
- Trial name
- EPIME (NCT04378634)
- Testing
- Exercise, Mental Stress Test
- Where
- Belgium
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Work Productivity and Activity Impairment in Workers With Chronic C Hepatitis, Fatigue in Workers With Chronic C Hepatitis
Acetyl-L-Carnitine Supplementation During HCV Therapy With Pegylated Interferon-α2b Plus Ribavirin
To assess the effects of Acetyl-L-Carnitine administration on work productivity, daily activity, and fatigue in subjects with chronic hepatitis C treated with Pegylated-Interferon-α2b and Ribavirin.
- Conditions
- Work Productivity and Activity Impairment in Workers With Chronic C Hepatitis, Fatigue in Workers With Chronic C Hepatitis, Fatigue
- Trial name
- NCT01913964
- Testing
- Acetylcarnitine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Catania
Chronic Obstructive Pulmonary Disease (COPD)
Investigation of the Effect of Structured Energy Conservation Techniques Training on COPD Patients
Chronic obstructive pulmonary disease (COPD) is a heterogeneous lung disease characterized by chronic respiratory symptoms (dyspnea, cough, sputum production, and/or exacerbations) due to persistent, often progressive airflow…
- Trial name
- NCT07581132
- Testing
- Structured Energy Conservation Techniques Training
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Akdeniz University
Anxiety Depression, Post Traumatic Stress Disorder
Neuropsychological Sequelae and Long COVID-19 Fatigue
An association of fatigue with post-viral neuropsychological disturbs has been reported. Among patients hospitalized with COVID-19 there is an increased incidence of anxiety and depression symptoms.
- Conditions
- Anxiety Depression, Post Traumatic Stress Disorder, Mental Fatigue, COVID-19
- Trial name
- PostCoV2Psy (NCT05323318)
- Testing
- Neuropsychological Sequelae
- Where
- 6 sites in Portugal
- Volunteers
- 200 people
- Sponsor
- Centro Hospitalar Universitario do Algarve
Intradialytic Fatigue, Chronic Kidney Disease
Manual Acupuncture for Intradialytic Fatigue in CKD Patients
This study aims to evaluate the immediate effects of acupuncture therapy at three specific acupuncture points (PC6, ST36, and KI3) on intradialytic fatigue in patients with chronic kidney disease undergoing regular hemodialysis.
- Conditions
- Intradialytic Fatigue, Chronic Kidney Disease, Acupuncture
- Trial name
- NCT07887386
- Testing
- Manual Acupuncture
- Where
- Indonesia
- Volunteers
- 19 people
- Sponsor
- Universitas Indonesia
Chronic Myeloid Leukemia, Chronic Myeloid Leukemia, Chronic Phase
The Analysis of Fatigue on Tyrosine Kinase Inhibitor Therapy in Chronic Myeloid Leukaemia
The goal of this clinical study is to gain essential insights into the relationship between Tyrosine kinase inhibitor (TKI) therapy and profound fatigue and abnormal sleep patterns using rest-activity monitoring (actigraphy) and…
- Conditions
- Chronic Myeloid Leukemia, Chronic Myeloid Leukemia, Chronic Phase, Fatigue, Sleep Disturbance
- Trial name
- TIRE (NCT06233890)
- Testing
- Motion watch
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Imperial College Healthcare NHS Trust
Apnea, Sleep, Chronic Fatigue Syndrome
Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment
The purpose of this study is to determine any sleep disordered breathing in veterans with Gulf War Syndrome (GWS) and compare it to healthy normal asymptomatic Gulf War veterans.
- Trial name
- NCT00252629
- Testing
- Nasal CPAP treatment during sleep
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- US Department of Veterans Affairs
Fatigue Syndrome, Chronic, Inflammation
Evaluation of the Effects of Treatment With Bioarginin C in Adult Subjects Belonging to the Post-Covid Day Hospital
Long Covid could be much more frequent than it is thought to be. Few dwell on the great problem represented by the post covid syndrome.
- Trial name
- BC (NCT04947488)
- Testing
- Bioarginina C
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Milan
SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis
Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center?
The primary objective of the present research is to determine the effectiveness of Family Health Center of San Diego's Long COVID and Fatiguing Illness Recovery Program (LC\&FIRP) on clinician- and patient-level outcomes.
- Conditions
- SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, Post-acute Sequelae of SARS-COV-2 Infection
- Trial name
- LC&FIRP (NCT05167227)
- Testing
- Extension for Community Healthcare Outcomes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Family Health Centers of San Diego
Fatigue Syndrome, Chronic, Bone Tumor
The Assessment of Fatigue and Quality of Life in Patients With Bone Tumor,
The aim of the present observational study is to evaluate and describe the evolution over time of the fatigue and the quality of life of patients with bone tumor, in Rizzoli Orthopedic Institute, Chemotherapy ward, during the…
- Conditions
- Fatigue Syndrome, Chronic, Bone Tumor, Quality of Life
- Trial name
- Fatigue-ONCO (NCT04104750)
- Testing
- assessment scales (BFI, QLQ, TESS)
- Where
- Italy
- Volunteers
- 155 people
- Sponsor
- Istituto Ortopedico Rizzoli