Clinical trials: Chronic Functional Constipation
Functional Constipation (FC), Chronic Idiopathic Constipation (CIC)
A Study to Assess Adverse Events and Change in Symptoms With Linaclotide Versus Placebo in Pediatric Subjects, Ages 2 to 5 Years, With Functional Constipation
Functional constipation (FC) is a common healthcare problem in children of all ages, potentially due to genetic predisposition, inadequate fiber and fluid intake, and immobility.
- Trial name
- NCT05652205
- Testing
- Linaclotide
- Where
- 48 sites in United States, Bulgaria and 2 more
- Volunteers
- 123 people
- Sponsor
- AbbVie
Chronic Idiopathic Constipation
SP-304 Dose Ranging Study in Patients With Chronic Idiopathic Constipation
This is a Phase 2a, randomized, double-blind, placebo-controlled, 14-day repeat oral, dose ranging study to determine the safety, pharmacokinetics (PK) and pharmacodynamics (PD) effects of SP-304 in patients with chronic…
- Trial name
- CIC (NCT01053962)
- Testing
- SP-304 0.3 mg, SP-304 1.0 mg, SP-304 3.0 mg
- Where
- 14 sites in United States
- Volunteers
- 84 people
- Sponsor
- Bausch Health Americas, Inc.
Chronic Constipation
Physiotherapeutic Intervention in Children With Chronic Functional Constipation
The purpose of this study is to determine whether physiotherapy is effective in the treatment of the chronic functional constipation in children.
- Trial name
- NCT00906971
- Testing
- diaphragmatic breathing, isometric training of the abdominal muscles and abdominal massage
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Universidade Federal de Pernambuco
Chronic Idiopathic Constipation
Effects of Lubiprostone on Gastric Function in Patients With Chronic Idiopathic Constipation
This prospective study is designed to evaluate how lubiprostone may affect gastric motor and sensory function.
- Trial name
- NCT01460225
- Testing
- lubiprostone
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Chronic Constipation, Methanogenesis
Effect of Lubiprostone on Methanogenesis and Bowel Function in Chronic Constipation.
Lubiprostone, a chloride channel activator, has been shown to improve symptoms of chronic constipation, largely by enhancing chloride-rich intestinal fluid secretion.
- Trial name
- NCT01190020
- Testing
- Lubiprostone, Lubiprostone Control
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Augusta University
Constipation
The Efficacy and Safety Study of Electro-acupuncture for Severe Chronic Functional Constipation
The main purpose of this study is to evaluate efficacy of electro-acupuncture for severe functional constipation compared with sham acupuncture, used as placebo; the secondary purpose is to evaluate the safety and post-treatment…
- Trial name
- NCT01726504
- Testing
- electro-acupuncture
- Where
- China
- Volunteers
- 1,075 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences