Clinical trials: Chronic Graft-Versus-Host-Disease
Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q)
Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Total Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome
This phase II trial studies the side effects and best dose of iodine I 131 monoclonal antibody BC8 when given together with fludarabine phosphate, total-body irradiation, and donor stem cell transplant followed by cyclosporine…
- Conditions
- Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)
- Trial name
- NCT00119366
- Testing
- iodine I 131 monoclonal antibody BC8, fludarabine phosphate, total-body irradiation
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Fred Hutchinson Cancer Center
Spinal Cord Injury
Vitamin D and Calcium Study
Vitamin D aids in the body's ability to absorb calcium, it is a vital component in bone formation and break down. Reduced levels of vitamin D can indicate a vitamin deficiency and may depress serum calcium levels.
- Trial name
- NCT00857831
- Testing
- Vitamin D and Calcium
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Renal Failure, Chronic
Elimination of Protein-bound Uremic Retention Solutes by Prometheus Artificial Hepatic System Versus Conventional Dialysis
Comparison of the efficacy of dialysis by conventional dialysis versus Prometheus artificial hepatic system
- Trial name
- NCT00262353
- Testing
- Dialysis with different artificial devices
- Where
- Belgium
- Sponsor
- University Hospital, Ghent
Copd
Assessment of Trace Elements, Systemic Inflammation and Electrolytes
COPD is one of the most common causes of health problems worldwide. It is a disease that is associated with several systemic features that affect its morbidity and mortality.
- Trial name
- NCT05718453
- Testing
- Laboratory Tests
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Egymedicalpedia
Cardiorenal Metabolic Syndrome, Atherosclerotic Cardiovascular Disease
Effect of Secukinumab on Cardiorenal Outcomes in Patients With Cardiorenal Metabolic Syndrome and Atherosclerotic Cardiovascular Disease
This is a prospective, randomized, open-label, parallel-controlled clinical trial to evaluate the efficacy and safety of targeted IL-17A inhibition with secukinumab on cardiovascular and renal endpoints in 100 patients with…
- Conditions
- Cardiorenal Metabolic Syndrome, Atherosclerotic Cardiovascular Disease, Chronic Kidney Disease, Coronary Artery Disease
- Trial name
- NCT07704190
- Testing
- Secukinumab (75 mg), Standard Medical Therapy
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Pulmonary Arterial Hypertension
Tezosentan in Pulmonary Arterial Hypertension
Multicenter, Open-label, Non-comparative, Proof-of-concept, Phase 2a Study to Evaluate the Effect of a Single Infusion of Tezosentan on Pulmonary Vascular Resistance in Patients With Stable, Chronic Pulmonary Arterial…
- Trial name
- NCT01077297
- Testing
- Tezosentan
- Where
- 5 sites in United States, France and 1 more
- Volunteers
- 3 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Chronic Medical Illness
Efficacy of Attachment-based Compassion Therapy in Population With Chronic Medical Illness (CUIDA-TEC)
Compassion-Based Interventions are increasingly relevant as a potentially beneficial way to support people with chronic medical conditions and improve different outcomes related with the management of the disease.
- Trial name
- CUIDA-TEC (NCT04809610)
- Testing
- Internet attachment-based compassion therapy (iABCT).
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- University of Valencia
End Stage Renal Disease
Icodextrin Effects on Glucose Transporter Activation and Mediators of Fibrosis
The time on peritoneal dialysis may be limited for a significant number of patients that use this modality of renal replacement therapy due to the inability of the peritoneal membrane to clear solutes or achieve adequate…
- Trial name
- NCT02133313
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Alabama at Birmingham
Chronic Kidney Disease, Dialysis
Study of MCI-196 in Chronic Kidney Disease Stage V Subjects on Dialysis With Hyperphosphatemia
The primary objective of this study is to demonstrate the long-term safety and tolerability of MCI-196 in the subjects with stage V chronic kidney disease on dialysis with hyperphosphatemia.
- Conditions
- Chronic Kidney Disease, Dialysis, Hyperphosphatemia
- Trial name
- NCT00772382
- Testing
- MCI-196
- Where
- 21 sites in United States, Canada
- Volunteers
- 116 people
- Sponsor
- Tanabe Pharma Corporation
Chronic Neck Pain, Non-specific Neck Pain
Effects of Different Myofascial Release Techniques on Function in Chronic Non-Specific Neck Pain
This single-center, three-arm randomized controlled trial compares the effects of different myofascial release techniques, combined with a structured exercise program, on functional outcomes in individuals with chronic…
- Conditions
- Chronic Neck Pain, Non-specific Neck Pain, Myofascial Trigger Points, Myofascial Pain Syndrome - Neck
- Trial name
- MFR / CNNP (NCT07694882)
- Testing
- Hot Pack, Conventional TENS, Structured Exercise Program
- Where
- Cyprus
- Volunteers
- 84 people
- Sponsor
- Eastern Mediterranean University
Chronic Myeloproliferative Disorders, Leukemia
Donor Stem Cell Transplant in Treating Older or Frail Patients With Hematologic Cancer
RATIONALE: Giving low doses of chemotherapy, such as fludarabine and busulfan, before a donor bone marrow or peripheral blood stem cell transplant helps stop the growth of cancer cells.
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00296023
- Testing
- anti-thymocyte globulin, filgrastim, therapeutic allogeneic lymphocytes
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of California, San Francisco
Cerebral Palsy
Effects of Mirror Therapy on Lower Extremity in CP Children
A non-progressive condition that harms the developing brain both during and after birth is cerebral palsy (CP). It is a multifaceted syndrome marked by abnormalities in movement and posture, along with concomitant sensory-motor…
- Trial name
- NCT06673823
- Testing
- Mirror therapy, conventional therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Chronic Kidney Diseases
The Efficacy of Physical Activity on Improving Health Outcomes for Renal Transplant Patients
The purpose of this study is to see whether a physical activity intervention improves fitness, strength and reduces sedentary behavior.
- Trial name
- NCT04054323
- Testing
- Physical Activity Intervention
- Where
- United States
- Sponsor
- University of Pittsburgh
Diabetes Mellitus, Hypertension
Community-based E-Health Program for Older Adults Living With Chronic Diseases
With increased aging population, there is a higher rate of having chronic diseases and cognitive impairment. In order to achieve successful aging, it is important for community-dwelling older adults to perform better…
- Conditions
- Diabetes Mellitus, Hypertension, Hyperlipidemias
- Trial name
- CeHP (NCT04560296)
- Testing
- Community-based E-Health Program, usual self-management and follow up with doctors/nurse
- Where
- 9 sites in Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Chronic Wound
Evaluating Wound Healing With Next Science Gel & Wash.
This is a 12-week, single-site, open-label prospective study in adult with a chronic wound diagnosis. Subjects will be randomized in equal numbers to either the control treatment arm, antimicrobial control treatment arm, or Next…
- Trial name
- NCT03738579
- Testing
- Next Science Group, Control Group, Antibacterial Control Group
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Next Science TM
Depression, Chronic Disease
Group Self-Management of Depression and Medical Illness
This project addresses the important public health need to reduce ethnic disparities in depression care by pilot testing and refining a culturally tailored, low-cost intervention for improving both depression and general medical…
- Conditions
- Depression, Chronic Disease, Hispanic Americans
- Trial name
- NCT02017262
- Testing
- Self-management group, Enhanced usual care
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Southern California
Leukemia, Acute Myeloid Leukemia
Allogeneic Transplantation Using Timed Sequential Busulfan and Fludarabine Conditioning
The goal of this clinical research study is to learn if giving busulfan and fludarabine before a stem cell transplant can help control the disease better than the standard method in patients with leukemia, lymphoma, multiple…
- Conditions
- Leukemia, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, Chronic Myeloid Leukemia
- Trial name
- NCT01572662
- Testing
- Fludarabine monophosphate, Busulfan, Stem Cell Infusion
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- M.D. Anderson Cancer Center
End Stage Renal Disease on Dialysis
Dietary Therapy in Dialysis Patients
Patients with end-stage kidney disease have hyperphosphatemia and accumulated uremic toxin level due to decreased urine excretion ability.
- Trial name
- NCT04505462
- Testing
- Therapeutic diet
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- Far Eastern Memorial Hospital
Chronic Hepatitis B
Efficacy and Safety of Entecavir Maleate Tablets in Chinese Patients With Hepatitis B
The purpose of this study is to evaluate the safety and efficacy of Entecavir maleate tablets in Chinese patients with hepatitis B
- Trial name
- NCT01926288
- Testing
- Entecavir maleate tablets, blank Baraclude tablets, Blank maleate entecavir tablets
- Where
- 9 sites in China
- Volunteers
- 287 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Shoulder Pain, Chronic Pain
Feasibility of Near-infrared Spectroscopy to Measure Cortical Pain Pathway (Brain) Activation During Dry Needling
The benefit experienced by some patients when treated with dry needling,1 combined with the field-expedient nature of this intervention, make dry needling uniquely suited for the military healthcare environment.
- Conditions
- Shoulder Pain, Chronic Pain, Musculoskeletal Injury
- Trial name
- NCT04170803
- Testing
- Dry Needling
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Army-Baylor University Doctoral Program in Physical Therapy
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