Clinical trials: Chronic Health Condition
Chronic Obstructive Pulmonary Disease
QVA Mechanistic Efficacy Study (Receptor Effects, Etc)
The purpose of this study was to assess global ventilated lung volume in moderate to severe COPD patients using MRI lung imaging after treatment with QVA149 compared to placebo.
- Trial name
- NCT02634983
- Testing
- QVA149
- Where
- 3 sites in United Kingdom
- Volunteers
- 31 people
- Sponsor
- Novartis Pharmaceuticals
Opioid Use Disorder (OUD), Chronic Pain
Mindfulness Texting for Medication Adherence and Chronic Pain Management
The goal of this clinical trial is to examine the effects of reminder and mindfulness text messages based on integrated Acceptance and Commitment Therapy and Mindfulness Based Relapse Prevention (ACT+MBRP) on medication adherence…
- Trial name
- MiMA (NCT07711795)
- Testing
- Mindfulness text messages
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of New Mexico
Chronic Obstructive Pulmonary Disease, Asthma
Exploring Respiratory Health Outcomes From Sustained Use of Efficient Cookstoves
Household air pollution (HAP) is a leading risk factor for global burden of disease. Resource-constrained communities of the world especially women and children are significantly impacted by this challenge.
- Trial name
- STAR (NCT03726957)
- Testing
- Improved Cookstoves
- Volunteers
- 208 people
- Sponsor
- Boston College
Insomnia Chronic, Insomnia Due to Medical Condition
Sleep Well Despite Persistent Pain Symptoms
Background: The prevalence of comorbid insomnia is 8-10 times higher in patients with chronic pain than in the general population.
- Conditions
- Insomnia Chronic, Insomnia Due to Medical Condition, Pain, Chronic
- Trial name
- Sleep-Well (NCT06351839)
- Testing
- Sleep-Well despite persistent pain, TAU (treatment-as-usual)
- Where
- Norway
- Volunteers
- 106 people
- Sponsor
- University of Tromso
Long COVID, Acute COVID-19
Chronic Stress as a Risk Factor for Long COVID
The disease caused by the pathogen SARS-CoV-2 is known as coronavirus disease with the acronym COVID-19. The acute phase of this condition typically lasts one to two weeks and usually results in a full recovery.
- Trial name
- StressLoC (NCT05652634)
- Where
- Austria
- Volunteers
- 380 people
- Sponsor
- Medical University of Graz
Chronic Insomnia Disorder, Circadian Rhythm Disorders
Translation and Validation of the French Version of the Sleep Regularity Questionnaire: a New Tool to Address the the Challenge of Sleep Health
Sleep is an essential function for physical and mental health. The mismatch between biological rhythms and the social rhythms of individuals is increasingly common in modern societies.
- Trial name
- PRIMO (NCT06727448)
- Testing
- SRQ questionnaire
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Myocardial Infarction, Hypertension
Reducing Blood Pressure in Patients With High Cardiovascular Risk
BP-REACH is a study of a team-based (pharmacist and health coach) program for lowering blood pressure for people with a prior stroke or heart attack in the Los Angeles Department of Health Services healthcare system.
- Conditions
- Myocardial Infarction, Hypertension, Stroke
- Trial name
- BP-REACH (NCT05937685)
- Testing
- BP REACH Intervention
- Where
- 4 sites in United States
- Volunteers
- 546 people
- Sponsor
- University of Southern California
Hepatitis C, Chronic, HIV Infection
ADHEPTA Study: Adherence Questionnaire in Hepatitis C
Main objective: To study and validate a questionnaire measuring treatment adherence in patients with Hepatitis C virus (HCV) infection.
- Trial name
- ADHEPTA (NCT00998621)
- Testing
- Adherence questionnaire
- Where
- Spain
- Volunteers
- 1,120 people
- Sponsor
- Fundacion IMIM
Foot Ulcer, Diabetic, Diabetic Angiopathies
Efficacy of a Low-Molecular-Weight Heparin (Bemiparin) in the Treatment of Chronic Foot Ulcers in Diabetic Patients
To assess the efficacy of bemiparin (low molecular weight heparin) for 3 months in the treatment of chronic foot ulcers in diabetic patients.
- Trial name
- NCT00399425
- Testing
- bemiparin (low molecular weight heparin)
- Volunteers
- 84 people
- Sponsor
- Spanish National Health System
Medication Adherence, Poly Pharmacy
Itaca App vs. Usual Care for Medication Adherence in Older Adults on Polypharmacy
The goal of this clinical trial is to learn if the use of a mobile app called Itaca improves medication adherence in older adults (aged ≥65) in a home care setting.
- Conditions
- Medication Adherence, Poly Pharmacy, Chronic Disease, Older Adults (65 Years and Older)
- Trial name
- NCT07631676
- Testing
- mobile app, Usual Care Group
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Roma La Sapienza
Brain Injuries
Brain Injury Therapy of Exercise and Enriched Environment
The purpose of this study is to determine whether exercise or exercise with enrichment is beneficial in individuals who previously had a head injury.
- Trial name
- BITEEE (NCT03256643)
- Testing
- Exercise, Delayed Exercise, Exercise and enrichment
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Wayne State University
Chronic Disease
Development of a Community Engagement Activity for Advance Care Planning
This study will determine the feasibility of using an end-of-life conversation game (called "My Gift of Grace") as a community engagement activity series to help caregivers, patients with chronic illness, and/or their families…
- Trial name
- CERC (NCT02575417)
- Testing
- Conversation Game
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Chronic Pain, Peer Review, Health Care
Evaluation of a Interdisciplinary Pain Program Among Patients With Chronic Pain and Frequent Emergency Department Visits
While significant advances in pain management have occurred in the last 20 years, the majority of patients with chronic pain (CP) are unable to access evidence-based treatment at either the primary or tertiary care level.
- Conditions
- Chronic Pain, Peer Review, Health Care, Interdisciplinary Communication
- Trial name
- CIPAP (NCT02237391)
- Testing
- CIPAP Program, Treatment as Usual (TAU)
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Ottawa Hospital Research Institute
Chronic Disease
Health-related Quality of Life in Patients at Nordic Clinic
Nordic Clinic is a private clinic for personalised treatment based on the Functional Medicine concept. In summary, functional medicine is aimed at addressing the lifestyle and behavioral factors that are believed to contribute to…
- Trial name
- NCT04611074
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- Nordic Clinic Stockholm
HIV, Tuberculosis
Evaluation of South Africa's National Adherence Strategy
NOTE THAT THE STUDY IS LED BY SOUTH AFRICA NATIONAL DEPARTMENT OF HEALTH AND WORLD BANK WITH SUPPORT FROM BOSTON UNIVERSITY. The South Africa National Department of Health (NDOH) intends to launch its newly developed National…
- Conditions
- HIV, Tuberculosis, Diabetes, Hypertension
- Trial name
- ENHANCE (NCT02536768)
- Testing
- Minimum package of interventions to improve ART adherence
- Where
- South Africa
- Volunteers
- 8,020 people, healthy volunteers welcome
- Sponsor
- Boston University
Periodontitis, Adult
Association of Periodontitis With Oral Health Related Quality of Life
Objective: The aim of this study was to investigate the impact of periodontitis on oral health-related quality of life (OHQoL) and the factors may associated with OHQoL.
- Trial name
- NCT04240015
- Testing
- Oral-Dental Health-Related Quality of Life-United Kingdom (OHRQoL-UK) scale
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baskent University
Chronic Pain, Depression, Anxiety
Cognitive Behavioral Therapy and Real-Time Pain Management Intervention for Sickle Cell Via Mobile Applications
The investigators are conducting a comparative effectiveness trial among adult patients with sickle cell disease (SCD) who report chronic pain (N = 350), randomized to receive either mobile phone-delivered computerized cognitive…
- Conditions
- Chronic Pain, Depression, Anxiety, Opioid Use
- Trial name
- CaRISMA (NCT04419168)
- Testing
- cCBT, m-Education
- Where
- 7 sites in United States
- Volunteers
- 359 people
- Sponsor
- University of Pittsburgh
Eating Behavior, Fibromyalgia
Eating Behaviours in Female Patients With Fibromyalgia
The Relationship Between Eating Behaviours and Health Status of Female Patients with Fibromyalgia
- Conditions
- Eating Behavior, Fibromyalgia, Health Status
- Trial name
- NCT04248478
- Testing
- Eating Behaviours, Health Status
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Frailty, Chronic Pain
Effectiveness of a Physical Activity Intervention for Pre-frail Older Adults With Chronic Pain.
The purpose of this investigation is to evaluate the effectiveness of a multicomponent structured physical exercise program for adults aged 65 years or more, classified as pre-frail and with chronic pain to improve the Perceived…
- Conditions
- Frailty, Chronic Pain, Old Age; Debility
- Trial name
- NCT04045535
- Testing
- Physical Activity Program, Usual care
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Gerencia de Atención Primaria, Madrid
Chronic Obstructive Pulmonary Disease
Effects of NIMV on the Health Status of Chronic Obstructive Pulmonary Disease (COPD )Patients
In this proposal, we will implement a randomized controlled trial to determine whether nocturnal NIMV applied for 3 months: 1) improves (disease-specific) health related quality of life (HRQL) of COPD patients compared to a…
- Trial name
- NCT00114426
- Testing
- non-invasive mechanical ventilation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
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