Clinical trials: Chronic Health Condition
B Acute Lymphoblastic Leukemia Associated With Down Syndrome, Down Syndrome
A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
This study attempts to learn more about the health of persons with Down syndrome after treatment for acute leukemia. Children with Down syndrome are at increased risk for side effects during treatment for acute leukemia, but it…
- Conditions
- B Acute Lymphoblastic Leukemia Associated With Down Syndrome, Down Syndrome, Myeloid Leukemia Associated With Down Syndrome
- Trial name
- NCT05702645
- Testing
- Biospecimen Collection, Clinical Evaluation, Neurocognitive Assessment
- Where
- 73 sites in United States, Canada
- Volunteers
- 330 people
- Sponsor
- Children's Oncology Group
Chronic Pain
Effects of Biopsychosocial Models Based on Pain or Functionality in the Treatment of Chronic Musculoskeletal Pain
The objective of this study is to evaluate whether a functionality-centered biopsychosocial model can improve clinical outcomes in the care of individuals with chronic musculoskeletal pain treated in a specialized healthcare…
- Trial name
- NCT07544745
- Testing
- Pain-Centered Biopsychosocial Model, Functionality-Centered Biopsychosocial Model Group
- Volunteers
- 24 people
- Sponsor
- Universidade Federal de Sao Carlos
Disparities, Community Health Workers
Philly CEAL- DECIDE+ Adaptation
Cardiovascular disease (CVD) disproportionately affects racial/ethnic minorities and underserved populations in Philadelphia. This study aims to evaluate the effectiveness of an enhanced community health worker (CHW) program that…
- Conditions
- Disparities, Community Health Workers, Cardiovascular Diseases, Social Determinants of Health (SDOH)
- Trial name
- NCT06732102
- Testing
- DECIDE, Community Health Worker Support
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Post-surgical Pain, Pain, Acute
Online Psychology Program for Chronic Pain After Surgery
This project will evaluate the feasibility of a new fully self-guided online Acceptance and Commitment Therapy (ACT) program entitled Advancing Online Psychology Tools for the Transitional Pain Service (ADOPT-TPS), developed on…
- Conditions
- Post-surgical Pain, Pain, Acute, Pain, Chronic, Post-Surgical Pain, Chronic
- Trial name
- ADOPT-TPS (NCT06455345)
- Testing
- Self-Guided Online ACT Program, Treatment As Usual
- Where
- 2 sites in Canada
- Volunteers
- 68 people
- Sponsor
- University Health Network, Toronto
Low Back Pain
Interprofessional Rehabilitation for Adults With Chronic Non-specific Low Back Pain
The primary aim of the study is to analyse the long-term effectiveness of an interprofessional and interdisciplinary rehabilitation program named "PASTOR", with a biopsychosocial approach for participants with chronic…
- Trial name
- PASTOR (NCT02056951)
- Testing
- Multidisciplinary rehabilitation, Interprofessional rehabilitation
- Where
- 4 sites in Germany
- Volunteers
- 536 people
- Sponsor
- University of Erlangen-Nürnberg
Juvenile; Scoliosis, Scoliosis Idiopathic
Digital Health Psychosocial Intervention for Adolescent Spine Surgery Preparation and Recovery
This is a randomized controlled trial to test effectiveness of the SurgeryPal intervention vs. education control to improve acute and chronic pain and health outcomes in youth undergoing major musculoskeletal surgery.
- Conditions
- Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital
- Trial name
- SurgeryPal (NCT04637802)
- Testing
- CBT (SurgeryPal), Education
- Where
- United States
- Volunteers
- 433 people
- Sponsor
- Seattle Children's Hospital
Chronic Disease, Obesity
Active and Healthy Brotherhood: A Program for Chronic Disease Self-Management for Black Men
This study will test ways to improve health behaviors using an intervention that has been specially designed for African-American men.
- Conditions
- Chronic Disease, Obesity, Hypertension, Diabetes
- Trial name
- NCT02362737
- Testing
- Active and Healthy Brotherhood (AHB)
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- Gramercy Research Group
Lung Cancer
Lung Cancer Screening Implementation Among Employees at Lyon Hospital
Several randomized studies have demonstrated the efficiency of lung cancer screening (LCS) on mortality rates. However, screening efficiency is related to the targeted population and the participation rate.
- Trial name
- ILYAD (NCT05452200)
- Testing
- Solicitation for lung cancer screening, added exams to the usual lung cancer screening
- Where
- 3 sites in France
- Volunteers
- 600 people
- Sponsor
- Hospices Civils de Lyon
COVID-19
Impact of Long COVID-19 on the Health and Quality of Life of Military Personnel (Active or Retired) and Their Families
Severe and sometimes irreversible sequelae are observed in people who have developed a severe form of COVID-19 (pulmonary, cardiovascular, renal, neurological sequelae among others).
- Trial name
- IMP@LA (NCT05200832)
- Testing
- Online questionnaire, Semi-structured interview
- Where
- France
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Child Development, Pain
Validation of the Spanish Version of the Conceptualization of Pain Questionnaire
The goal of this observational study is to develop a questionnaire to assess a child's concept of pain and to evaluate its psychometric properties in schoolchildren aged 8-17 years.
- Conditions
- Child Development, Pain, Adolescent Behavior
- Trial name
- COPAQ-S (NCT06114927)
- Testing
- Validation of a questionnaire
- Where
- Spain
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Access to Health Services, Health Disparity, Minority and Vulnerable Populations
Become of Patients From the Permanent Access to Care (PASS) in Cayenne, French Guyana, Suffering From a Chronic Disease (High Blood Pressure - Diabetes) in the Common Law Schemes
It is an observational research, conducted at the Cayenne hospital about the future of hypertensive and/or diabetic patients after their follow-up at the Permanent Access to care (PASS).
- Conditions
- Access to Health Services, Health Disparity, Minority and Vulnerable Populations, Chronic Disease, Social Security
- Trial name
- PASSyDroit (NCT05788731)
- Where
- French Guiana
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Chronic Disease, Goals
Effectiveness of a Personalized Health Profile on Specificity of Self-Management Goals
With a growing number of people living with chronic diseases, the need to empower people for self-management is rising. A key element in self-management is goal setting but the extent to which meaningful actionable goals (i.e.…
- Trial name
- NCT04175795
- Testing
- My Personal Brain Health Dashboard
- Where
- Canada
- Volunteers
- 420 people
- Sponsor
- McGill University
COVID-19, Diabetes Mellitus
Incidence of Diabetes After a COVID-19 Infection
Prospective observational study of the POINTED consortium to evaluate whether new diagnoses of diabetes mellitus, occur significantly more frequently in the post-acute phase of a laboratory-confirmed SARS-CoV-2 infection than in…
- Trial name
- POINTED_Diab (NCT05524792)
- Testing
- no interventional study
- Where
- Germany
- Volunteers
- 157,134 people
- Sponsor
- InGef - Institute for Applied Health Research Berlin GmbH
COPD, Asthma
Health Effects of Secondhand Smoke Exposure in Outdoor Smoking Areas in Patients With COPD and Asthma ( TackSHSWP5 )
Within the TackSHS project (H2020 project grant agreement No 681040), we will conduct a clinical research study, aiming at: i) to measure respiratory health effects when exposed to secondhand smoke (SHS) in patients with asthma…
- Conditions
- COPD, Asthma, Second Hand Tobacco Smoke
- Trial name
- TackSHSWP5 (NCT03074734)
- Testing
- Exposure to secondhand tobacco smoke
- Volunteers
- 60 people
- Sponsor
- Institut Català d'Oncologia
Chronic Disease, Hypertension
Sí Texas Hope Family Health Center
This study evaluated whether uninsured patients living at or below 200% of the federal poverty level who received enhanced, culturally-relevant, integrated behavioral health services were more likely to improve health outcomes…
- Conditions
- Chronic Disease, Hypertension, Diabetes, Hypercholesterolemia
- Trial name
- NCT03916016
- Testing
- Enhanced Integrated Behavioral Health Care, Usual Care
- Volunteers
- 585 people, healthy volunteers welcome
- Sponsor
- Health Resources in Action, Inc.
Chronic Disease, Mental Health
Optimizing Behavioral Health Homes for Adults With Serious Mental Illness
Adults with serious mental illness (SMI) frequently have unmet medical needs which place them at risk for adverse health outcomes.
- Conditions
- Chronic Disease, Mental Health, Behavioral Health, Cardiovascular Disease
- Trial name
- PCORI OH (NCT02318797)
- Testing
- Patient Self-Directed Care, Provider-Supported Integrated Care
- Where
- United States
- Volunteers
- 1,229 people
- Sponsor
- University of Pittsburgh
Acute MI, Heart Failure
Cardiovascular Kidney and Metabolic Health Assessment and Patient Empowerment
The primary objective of CHAPERONE solution is to evaluate the efficacy of engaging, assessing, and enabling long term treatment strategy with Health Artificial Intelligence (AI) Chatbot, Copilot, Large Language Model (LLM) and…
- Conditions
- Acute MI, Heart Failure, Diabetes Mellitus, Kidney Disease
- Trial name
- CHAPERONE-CKM (NCT07403669)
- Testing
- CHAPERONE AI, CKMiq AI, Quality of Life
- Where
- 5 sites in United States, Sweden
- Volunteers
- 300 people
- Sponsor
- Aventyn, Inc.
Schizophrenia, Physical Activity
The Application of Wearable Technology to Improve the Physical Activity Level of People With Chronic Mental Illness
The object is to develop a physical activity promotion program by applying social cognitive theory and wearable technology and evaluate its feasibility in people with MI Stage I: Accuracy, Acceptability, Feasibility.
- Conditions
- Schizophrenia, Physical Activity, Health Knowledge, Attitudes, Practice
- Trial name
- NCT03408327
- Testing
- Wearable technology, LINE group, Group activities
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Lifestyle-related Condition, Obesity
MyLife: A Digital Health Coaching Program
Lifestyle behaviors such as sleep, diet, and physical activity, are implicated in a number of chronic conditions including hypertension, obesity, diabetes, heart failure, and obstructive sleep apnea.
- Conditions
- Lifestyle-related Condition, Obesity, Sedentary Lifestyle, PreDiabetes
- Trial name
- NCT03529903
- Testing
- Health Coaching
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Los Angeles
Chronic Fatigue Syndrome
Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
The main aim of the study is to examine the effect of oral CoQ10 plus NADH (Reconnect®) supplementation twice daily for 8-weeks on the changes in fatigue perception, sleep disturbances, autonomic dysfunction and HRQoL assessed by…
- Trial name
- CONNeCT (NCT03186027)
- Testing
- Coenzyme Q10 plus NADH, phosphoserine plus vitamin C
- Where
- Spain
- Volunteers
- 282 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
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