Clinical trials: Chronic Heart Failure
Heart Failure, Pulmonary Disease, Chronic Obstructive
Virtual Nurse and Social Worker Palliative Care Team to Improve Quality of Life in Veterans With Heart Failure or COPD
Many Veterans living with heart failure or chronic obstructive pulmonary disease (COPD) experience significant symptoms - such as breathlessness, fatigue, depression, and anxiety -that reduce their quality of life.
- Conditions
- Heart Failure, Pulmonary Disease, Chronic Obstructive, Interstitial Lung Disease
- Trial name
- VITALVET:ADAPT (NCT07714252)
- Testing
- Virtual Nurse and Social Worker Palliative Care Team, Enhanced Implementation Support, Standard Implementation Support
- Where
- 7 sites in United States
- Volunteers
- 420 people
- Sponsor
- VA Office of Research and Development
Renal Replacement Therapy, Renal Dialysis
A Clinical Trial of IntensiVE Dialysis
This study will assess clinical outcomes of extended weekly hours of haemodialysis (>= 24 hours per week) compared with standard hours of haemodialysis (<=18 hours/week) in people with ESKD.
- Conditions
- Renal Replacement Therapy, Renal Dialysis, End Stage Kidney Disease, End Stage Renal Disease
- Trial name
- ACTIVE (NCT00649298)
- Testing
- haemodialysis
- Where
- 40 sites in Australia, Canada and 2 more
- Volunteers
- 200 people
- Sponsor
- The George Institute
Heart Failure, Congestive Cardiac Failure
B-type NAtriuretic Peptide In Critically Ill : A Multicentric Diagnostic Study (B-rAPID)
Difficulty in breathing or increased rate of breathing are common causes of admission to intensive care unit. This may be due to heart failure, or other causes such as infection in the lungs.
- Conditions
- Heart Failure, Congestive Cardiac Failure, Dyspnoea
- Trial name
- B-RAPID (NCT01685385)
- Testing
- Patients who will receive the BNP test
- Where
- 4 sites in India
- Volunteers
- 800 people
- Sponsor
- Mahatma Gandhi Institute of Medical Sciences
Chronic Heart Failure, High Blood B-type (or Brain) Natriuretic Peptide (BNP) Level
Study to Demonstrate the Non-inferiority of Olmesartan Medoxomil Versus Candesartan Cilexetil in Reducing Blood B-type (or Brain) Natriuretic Peptide Levels at Week 24
This study will compare olmesartan medoxomil to candesartan cilexetil in reducing BNP, a prognostic biomarker of heart failure, at week 24
- Trial name
- OLMEBNP (NCT00679484)
- Where
- 11 sites in France, Germany and 1 more
- Volunteers
- 400 people
- Sponsor
- Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Heart Failure
Nutritional Improvement in Chronic Heart Failure Patients
To assess the effect over the nutritional status in patients who are malnourished with chronic heart failure, of an educational intervention and the provision of nutritional supplements.
- Trial name
- VAINICA (NCT02599935)
- Testing
- Hypercaloric beverages, standard treatment, educational structured counseling
- Where
- Spain
- Volunteers
- 76 people
- Sponsor
- Luis Guerra
Acute Heart Failure
Short Stay Unit vs Hospitalization in Acute Heart Failure
The majority of the over one million annual AHF hospitalizations originate from the emergency department. Admitting and re-admitting lower risk AHF patients who don't need prolonged hospitalization may increase their risk for…
- Trial name
- SSU-AHF (NCT03302910)
- Testing
- Short Stay Unit, Standard of Care
- Where
- 11 sites in United States
- Volunteers
- 194 people
- Sponsor
- Indiana University
Heart Failure
Registry of Pavia Chronic Heart Failure Patients-observational Study
Registry of Pavia chronic heart failure patients-observational study
- Trial name
- NCT07291219
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Chronic Heart Failure
A Clinical Trial to Compare the Pharmacokinetics and Safety of "BR1016C" With "BR1016D" in Healthy Volunteers
To evaluate the pharmacokinetic properties and safety of "BR1016C" and "BR1016D" in healthy adults.
- Trial name
- NCT05102266
- Testing
- BR1016C, BR1016D
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Nephrogenic Systemic Fibrosis, Renal Failure
Nephrogenic Systemic Fibrosis With Gadollinum
Recently there is increasing reports of NEPHROGENIIC SYSTEMIC FIBROSIS(NSF) in patients with severe renal failure mainly in patients under dialysis in whom gadollinum is being used.
- Trial name
- NSF (NCT01359345)
- Testing
- gadollinum
- Where
- Iran
- Volunteers
- 200 people
- Sponsor
- Imam Khomeini Hospital
Heart Failure, Left Bundle-Branch Block
Conduction System Pacing Versus Biventricular Resynchronization in Patients With Chronic Heart Failure
The purpose of this study is to evaluate the efficacy and safety of conduction system pacing versus biventricular pacing in patients with chronic heart failure with reduced ejection fraction and left bundle branch block.
- Conditions
- Heart Failure, Left Bundle-Branch Block, Cardiac Resynchronization, Conduction System Pacing
- Trial name
- PhysioSync-HF (NCT05572736)
- Testing
- Conduction system pacing, Biventricular pacing
- Where
- 14 sites in Brazil
- Volunteers
- 179 people
- Sponsor
- Hospital Moinhos de Vento
Heart Failure
Digoxin Versus Ivabradine in Heart Failure With Reduced Ejection Fraction
Study hypothesis: Comparing the effect of digoxin and ivabradine in chronic heart failure patients with a left ventricular ejection of 35% or lower and sinus rhythm with heart rate 70 beats per minute or higher, and who are…
- Trial name
- DIVA-REF (NCT02046044)
- Testing
- Digoxin, Ivabradine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli University
Chronic Heart Failure
Hospital-Community-Family-Care Management Platform for Chronic Heart Failure
The purpose of this study is to determine whether the Hospital-Community-Family-Care Management Platform for Chronic Heart Failure reduces the mortality, readmission rates and costs of the subjects with CHF.
- Trial name
- HCF-CMP-CHF (NCT02029287)
- Testing
- Hospital-Community-Family-Care Management Platform Online, Subjects with CHF via conventional clinic visit according to the latest relevant guidelines
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xiang Gu
Congestive Heart Failure
Hospital Versus Home Based Exercise in Patients With Chronic Stable Heart Failure
The objective of this study is to compare the effect of monitored, home-based exercise versus hospital-based exercise on the quality of life of patients with congestive heart failure.
- Trial name
- PEAK-HF (NCT01480921)
- Testing
- Home-based exercise training, Supervised hospital-based exercise training
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- McMaster University
Hypotension, Postoperative Complications
Biomarkers, Blood Pressure, BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardiac Surgery
Major adverse cardiovascular events (MACE) are a leading cause of serious complications and death following major noncardiac surgery.
- Conditions
- Hypotension, Postoperative Complications, Acute Coronary Syndrome, Heart Failure
- Trial name
- BBB (NCT02533128)
- Testing
- Liberal blood pressure management, Tight blood pressure management
- Where
- Switzerland
- Volunteers
- 458 people
- Sponsor
- Miodrag Filipovic, Prof. Dr. med.
Chronic Heart Failure With Reduced Ejection Fraction
An Observational Study Called ROVER to Learn More About How Well Vericiguat Works in People Who Were Newly Treated With Vericiguat in Routine Medical Care in Germany
This is an observational study in which data already collected from people treated with vericiguat are studied. In observational studies, only observations are made without participants receiving any advice or any changes to…
- Trial name
- ROVER (NCT06486844)
- Testing
- Vericiguat (Verquvo, BAY1021189)
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Bayer
Chronic Kidney Diseases, Hypertension
Real Clinical Practice Register of AlbUminuRia Detection in Patients With Previously undiAgnosed Chronic Kidney Disease
Real clinical practice register of Albuminuria detection in patients with previously undiagnosed chronic kidney disease
- Conditions
- Chronic Kidney Diseases, Hypertension, Chronic Heart Failure, Ischemic Heart Disease
- Trial name
- AURA (NCT05690009)
- Where
- Russia
- Volunteers
- 4,580 people
- Sponsor
- Eurasian Association of Therapists
Heart Failure, Chronic Kidney Diseases
Creating A Cardiorenal Multidisciplinary Team for Management HF and CKD Patients
Several drugs have been labeled as guideline-directed-medical therapies (GDMT) to improve overall health outcomes and slow the progression of disease in patients with heart failure (HF).
- Trial name
- NCT05531214
- Testing
- Multidisciplinary Care Coordination Team
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- George Washington University
Heart Failure
Implementing Standards of Care for Heart Failure Patients in General Practice - A Regional Disease Management Program
Heart failure (HF) is an important health problem. Most chronic HF management occurs in primary care. Although guidelines exist, there is an important implementation gap in current HF care in Belgium.
- Trial name
- NCT04334447
- Testing
- Improved primary care HF diagnostics, Heart Failure education, Structured transitional protocol planning post-discharge care
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- KU Leuven
Heart Failure
Significance of Regional Ventriculo-arterial Coupling in Patients With Chronic Heart Failure
The investigators hypothesize that the different components of arterial load are coupled with different components of LV function.
- Trial name
- NCT01298258
- Testing
- Aliskiren
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Heart Failure
Heart Failure Events Reduction With Remote Monitoring and eHealth Support Investigator Initiated Trial
The primary objective of the study is to evaluate the efficacy of a telemedicine-based follow-up strategy compared with usual care in the management of patients with chronic heart failure (HF) at high risk of clinical events.
- Trial name
- HERMeS (NCT03663907)
- Testing
- Telemonitoring
- Where
- Spain
- Volunteers
- 510 people
- Sponsor
- Hospital Universitari de Bellvitge