Clinical trials: Chronic Heart Failure (CHF)
Heart Failure With Reduced Ejection Fraction, HFrEF
VisONE Heart Failure Study: Pilot
The VisONE HF pilot is a feasibility pilot for evaluating the benefits and risks of chronically delivering Asymptomatic Diaphragmatic Stimulation in medical refractory heart failure patients using the VisONE™ implantable system…
- Trial name
- NCT03484780
- Testing
- VisONE ADS
- Where
- 3 sites in Georgia, Ukraine
- Volunteers
- 15 people
- Sponsor
- VisCardia Inc.
Chronic Obstructive Pulmonary Disease, Asthma
Effectiveness and Implementation of the Assessment of Burden of Chronic Conditions (ABCC)-Tool
This study is designed to evaluate the effectiveness and implementation of the Assessment of Burden of Chronic Conditions (ABCC)-tool for patients with COPD, asthma, diabetes mellitus type 2 or heart failure (and any combination…
- Conditions
- Chronic Obstructive Pulmonary Disease, Asthma, Diabetes Mellitus, Type 2, Heart Failure
- Trial name
- NCT04127383
- Testing
- Assessment of Burden of Chronic Conditions (ABCC)-tool
- Where
- Netherlands
- Volunteers
- 237 people
- Sponsor
- Maastricht University
Myocardial Ischemia
Safety and Feasibility Trial of Adipose-Derived Regenerative Cells in the Treatment of Chronic Myocardial Ischemia
This is a prospective, randomized, placebo-controlled, double blind safety and feasibility clinical trial.
- Trial name
- ATHENA (NCT01556022)
- Testing
- ADRCs processed by the Celution System
- Where
- 8 sites in United States
- Volunteers
- 28 people
- Sponsor
- Cytori Therapeutics
Heart Failure
Alleviate-HF-2 Study
Patients with heart failure and preserved left ventricular ejection fraction (HFpEF, EF ≥ 50%) or mid-range left ventricular ejection fraction (HFmrEF, 40% < EF < 50%) with mild to moderate functional limitation will be evaluated…
- Trial name
- NCT04838353
- Testing
- ALV1 System
- Where
- 5 sites in Australia, Canada and 2 more
- Volunteers
- 13 people
- Sponsor
- Alleviant Medical, Inc.
Heart Failure NYHA Class IV
Ivabradine in Stage D Heart Failure Patients on Chronic Inotropes
Ivabradine, a selective inhibitor of the If current in the sinoatrial node, provides heart rate reduction and leads to a reduction in heart failure hospitalizations.
- Trial name
- NCT03631654
- Testing
- Ivabradine
- Sponsor
- University of Maryland, Baltimore
Heart Failure
Canadian e-Platform to Promote Behavioral Self-Management in Chronic Heart Failure: CHF-CePPORT
Chronic Heart Failure (CHF) is a growing public health issue in Canada. Hospital re-admission within 1-year after diagnosis is 25-40%, and the 5-year rate of CHF death is 50%.
- Trial name
- CHF-CePPORT (NCT01864369)
- Testing
- eCounseling + Usual Care
- Where
- 3 sites in Canada
- Volunteers
- 248 people
- Sponsor
- University Health Network, Toronto
Sleep Apnoea Syndrome
Sleep Apnoea Syndrome Without Chronic Heart Failure
It is the objective of this study to collect scientific data of sleep apnoea syndrome patients´ cardiac and respiratory function by additional sensors.
- Trial name
- NCT01775241
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- RWTH Aachen University
Chronic Heart Failure, Central Sleep Apnea
Effect of Adaptive Servoventilation on Cardiac Function in Chronic Heart Failure and Cheyne-Stokes Respiration
Sleep disordered breathing is common in patients with chronic heart failure. Adaptive servoventilation is a novel method of treatment central sleep apnoea, especially associated with Cheyne-Stokes-respiration.
- Conditions
- Chronic Heart Failure, Central Sleep Apnea, Cheyne-Stokes Respiration
- Trial name
- NCT01212705
- Testing
- Adaptive servoventilation
- Where
- Poland
- Sponsor
- Military Institute od Medicine National Research Institute
Right Ventricular Dysfunction
New Echocardiographic Methods for Right Ventricular Function.
Aims of this study are the evaluation of new echocardiographic methods (3D/4D- and strain-echocardiography) for measurement of the right ventricular (RV) function .
- Trial name
- NEW-RV (NCT01230294)
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Congestive Heart Failure
Cell-Wave Study: Combined Extracorporal Shock Wave Therapy and Intracoronary Cell Therapy in Chronic Ischemic Myocardium
Extracorporal shock wave therapy is performed prior to cell therapy for induction of therapeutic neovascularization and improvement of homing of bone marrow progenitor cells in patients with chronic ischemic heart disease…
- Trial name
- NCT00326989
- Testing
- intracoronary stem cell therapy
- Where
- Germany
- Volunteers
- 103 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Heart Failure
Clinical Data Collection Study Using CPM System
This study will assess the deployment of the ADI CPM System in a home setting and determine the interoperability of the CPM System within existing care pathways for HF patients.
- Trial name
- NCT06007079
- Testing
- CPM Device
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Analog Device, Inc.
Copd, Heart Failure
The Effect of Using Virtual Reality Glasses on Post-Care Pain and Comfort Level in Intensive Care Patients
The aim of this study is to determine the level of pain and comfort associated with the implementation of virtual reality prior to nursing care in patients undergoing treatment in the intensive care unit.
- Conditions
- Copd, Heart Failure, Intensive Care Unit Syndrome, Renal Failure
- Trial name
- NCT06923982
- Testing
- virtual reality, experimental group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Cardiac Allograft Vasculopathy, Chronic Rejection of Cardiac Transplant
Heart Failure After Heart Transplantation Due to Chronic Rejection
This study will investigate the prevalence of allograft vasculopathy and unexplained graft dysfunction during long-term follow-up after heart transplantation. Risk factors as well diagnostic approaches will be investigated.
- Conditions
- Cardiac Allograft Vasculopathy, Chronic Rejection of Cardiac Transplant, Graft Dysfunction
- Trial name
- AVALON (NCT03808324)
- Testing
- Diagnostic investigations
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Sahlgrenska University Hospital
Heart Failure, Chronic Heart Failure
A Multicenter Registry to Study the Characteristics and Outcomes of Jordanian Heart Failure Patients.
Heart Failure research registry is a collection of computerized information about individuals with heart failure. The database in this registry is obtained from several Jordanian medical centers which will represent an extremely…
- Conditions
- Heart Failure, Chronic Heart Failure, Acute Heart Failure
- Trial name
- JoHFR (NCT04829591)
- Testing
- observational
- Where
- Jordan
- Volunteers
- 2,219 people
- Sponsor
- Jordan Cardio Vascular Research Group
Metabolic Syndrome, Coronary Artery Disease
Brain, Cardiac Hemodynamics and Cognition During Exercise in Subjects With Various Cardiovascular Profiles
People with cardiovascular risk (CV) factors (obesity, diabetes, etc...) or established heart disease (such as coronary heart disease or chronic heart failure) often have cognitive dysfunction as compared to people without CV…
- Conditions
- Metabolic Syndrome, Coronary Artery Disease, Heart Failure
- Trial name
- COGNEX (NCT03018561)
- Testing
- Exercise and Cognitive testing
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Montreal Heart Institute
Chronic Heart Failure, Hyperuricemia
Allopurinol in Chronic Heart Failure
The purpose of this study is to discover whether the inhibition of the xanthine oxidase with allopurinol leads to a reduction of the production of oxygen free radicals in patients with CHF and thereby improves characteristics of…
- Trial name
- NCT00997542
- Testing
- Allopurinol
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- National Heart and Lung Institute
Congestive Heart Failure
Effect of a New Formulation of Torasemide (Prolonged Release)on Myocardial Fibrosis in Patients With Heart Failure.
Torasemide is a loop diuretic (pyridine-sulfonylurea)with a wide experience in the treatment of oedema associated to heart failure, kidney or liver disease and either in the treatment of arterial hypertension (alone or combined…
- Trial name
- TORAFIC (NCT00409942)
- Testing
- Torasemide Prolonged Release, Furosemide
- Where
- 23 sites in Spain
- Volunteers
- 142 people
- Sponsor
- Ferrer Internacional S.A.
Cardiomyopathy, Cardiac Arrhythmia
RF Surgical Sponge-Detecting System on the Function of Pacemakers and Implantable Cardioverter Defibrillators
If a surgical sponge is mistakenly left inside a patient's body after a surgical procedure, it can cause a serious infection. To prevent this from happening, a new device has been developed that uses radiofrequency (RF) signals…
- Conditions
- Cardiomyopathy, Cardiac Arrhythmia, Heart Failure, Chronic Thromboembolic Pulmonary Hypertension
- Trial name
- RF (NCT02111980)
- Testing
- RF Assure Scanning
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Chronic Heart Failure
Telehealth Management in HF Disparity Patients
In the US, racial and ethnic disparities persist, even when income, health insurance and care access are addressed. For example, there is a greater prevalence of chronic heart failure (CHF), higher rates of hospital use and…
- Trial name
- NCT02196922
- Testing
- Telehealth Self Management (TSM), Standard of Care
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Northwell Health
Heart Failure, Chronic Heart Failure
Wearable Tissue Oximetry During Arm Cuff Occlusion, Walking, and Standing Tests in Outpatients With Chronic Heart Failure
This prospective, single-center, observational pilot study evaluated an investigational wearable tissue oximeter (NIRSense Argus Oximetry System, also called Envello Core) in adult outpatients with chronic heart failure in New…
- Trial name
- NCT07874386
- Testing
- Argus Oximetry System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NIRSense Inc.