Heart FailureJoHFRNCT04829591
A Multicenter Registry to Study the Characteristics and Outcomes of Jordanian Heart Failure Patients.
An observational study of Heart Failure and Chronic Heart Failure, run by Jordan Cardio Vascular Research Group at 1 site in Jordan.
Trial summary
Heart Failure research registry is a collection of computerized information about individuals with heart failure. The database in this registry is obtained from several Jordanian medical centers which will represent an extremely valuable resource for epidemiological research on heart failure patients. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Heart Failure, Chronic Heart Failure, Acute Heart Failure
- What is being tested?
- observational
- How many people
- 2,219 participants
- Where
- 1 siteJordan
- Study dates
- 1 Jul 2021to 30 Dec 2023
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: patients 18 years old and older with HF will be recruited from all over Jordan , resulting in an initial sample estimate of approximately 4000 patients.
Who may be able to join
- Patients who are 18 years or older with Heart Failure diagnosis as defined by internationally recognized guidelines.
- Current residents of the Hashemite Kingdom of Jordan
Who cannot join
- Patients who refuse or unable to sign a consent form.
- Patient inability to follow up with provider
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Jordanian Heart Failure Registry (JoHFR)
Heart Failure research registry is a collection of computerized information about individuals with heart failure. The database in this registry is obtained from several Jordanian medical centers which will represent an extremely valuable resource for epidemiological research on heart failure patients.
Read the detailed description
Understanding the cause of Heart Failure (HF) and how the body will respond to it, is critical for an effective treatment. HF is a global problem with significant morbidity and mortality, despite improved understanding of the pathophysiology and a growing range of therapeutic options. Jordanian Heart Failure Registry (JoHFR) will be the first research project of heart failure prevalence in Jordan. It is undertaken by primary healthcare professionals with main aim to improve knowledge about the care of patients with HF. The investigators responsible for conducting this research are physicians and their teams who deal with heart failure patients in their outpatient and inpatient clinic centers including the public and private medical sectors in Jordan's medical community. Standards in the Hashemite kingdom of Jordan complies with the recognized good guideline directed medical practices internationally
- Conditions
- Heart Failure, Chronic Heart Failure, Acute Heart Failure
- Being tested
- observational
- Medical subject headings
- Heart Failure
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
observationalOther
Heart failure, non interventional
What is being measured
The primary outcome is the main question the study is designed to answer.
Cardiovascular death
The main objective of the JoHFR is to obtain reliable estimate of rates of cardiovascular death and or hospitalization for decompensated heart failure
Measured: 12 months
Secondary outcomes (1)
worsening kidney function
as compared to baseline eGFR
Measured: 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Apr 2021
- Study start1 Jul 2021
- Primary completion30 Dec 2023
- Study completion30 Dec 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (4)Papers the sponsor has linked to this study.
- Other trials for Heart FailureStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 2,219 participants (actual)
Sponsor and investigators
- Lead sponsor
- Jordan Cardio Vascular Research Group
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Hadi Abu-Hantash, University of Jordan
- Investigators
- Hadi M Abu-Hantash, MD,MSc, Study chair, Interventional Cardiovascular Innovation group
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04829591
- Sponsor's protocol ID
- JoCVRG
- Acronym
- JoHFR
- Status last verified
- Jul 2024
- First submitted
- 31 Mar 2021
- Last updated
- 19 Jul 2024
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Joseph P, Dokainish H, McCready T, Budaj A, Roy A, Ertl G, Gomez-Mesa JE, Leong D, Ezekowitz J, Hage C, Lanas F, Maggioni AP, Sliwa K, Zhu J, Rouleau J, Balasubramanian K, Yusuf S; G-CHF Investigators. A multinational registry to study the characteristics and outcomes of heart failure patients: The global congestive heart failure (G-CHF) registry. Am Heart J. 2020 Sep;227:56-63. doi: 10.1016/j.ahj.2020.06.002. Epub 2020 Jun 6.
PubMed 32679282Savarese G, Vasko P, Jonsson A, Edner M, Dahlstrom U, Lund LH. The Swedish Heart Failure Registry: a living, ongoing quality assurance and research in heart failure. Ups J Med Sci. 2019 Jan;124(1):65-69. doi: 10.1080/03009734.2018.1490831. Epub 2018 Aug 9.
PubMed 30092697Crespo-Leiro MG, Anker SD, Maggioni AP, Coats AJ, Filippatos G, Ruschitzka F, Ferrari R, Piepoli MF, Delgado Jimenez JF, Metra M, Fonseca C, Hradec J, Amir O, Logeart D, Dahlstrom U, Merkely B, Drozdz J, Goncalvesova E, Hassanein M, Chioncel O, Lainscak M, Seferovic PM, Tousoulis D, Kavoliuniene A, Fruhwald F, Fazlibegovic E, Temizhan A, Gatzov P, Erglis A, Laroche C, Mebazaa A; Heart Failure Association (HFA) of the European Society of Cardiology (ESC). European Society of Cardiology Heart Failure Long-Term Registry (ESC-HF-LT): 1-year follow-up outcomes and differences across regions. Eur J Heart Fail. 2016 Jun;18(6):613-25. doi: 10.1002/ejhf.566.
PubMed 27324686Bergethon KE, Ju C, DeVore AD, Hardy NC, Fonarow GC, Yancy CW, Heidenreich PA, Bhatt DL, Peterson ED, Hernandez AF. Trends in 30-Day Readmission Rates for Patients Hospitalized With Heart Failure: Findings From the Get With The Guidelines-Heart Failure Registry. Circ Heart Fail. 2016 Jun;9(6):10.1161/CIRCHEARTFAILURE.115.002594 e002594. doi: 10.1161/CIRCHEARTFAILURE.115.002594.
PubMed 27301467
Study at a glance
From the registry record, last updated by the sponsor on 19 Jul 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Jordanian Heart Failure Registry (JoHFR)
- ClinicalTrials.gov ID
- NCT04829591
- Acronym / sponsor ID
- JoHFR / JoCVRG
- Conditions
- Heart Failure, Chronic Heart Failure, Acute Heart Failure
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 2,219 participants (actual)
- Lead sponsor
- Jordan Cardio Vascular Research GroupUniversity, hospital or other
- Study start
- 1 Jul 2021 (actual)
- Primary completion
- 30 Dec 2023 (actual)
- Study completion
- 30 Dec 2023 (actual)
- First posted
- 2 Apr 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Heart Failure research registry is a collection of computerized information about individuals with heart failure. The database in this registry is obtained from several Jordanian medical centers which will represent an extremely valuable resource for epidemiological research on heart failure patients.
Detailed description
Understanding the cause of Heart Failure (HF) and how the body will respond to it, is critical for an effective treatment. HF is a global problem with significant morbidity and mortality, despite improved understanding of the pathophysiology and a growing range of therapeutic options. Jordanian Heart Failure Registry (JoHFR) will be the first research project of heart failure prevalence in Jordan. It is undertaken by primary healthcare professionals with main aim to improve knowledge about the care of patients with HF. The investigators responsible for conducting this research are physicians and their teams who deal with heart failure patients in their outpatient and inpatient clinic centers including the public and private medical sectors in Jordan's medical community. Standards in the Hashemite kingdom of Jordan complies with the recognized good guideline directed medical practices internationally
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- patients 18 years old and older with HF will be recruited from all over Jordan , resulting in an initial sample estimate of approximately 4000 patients.
Key inclusion criteria (2 listed)
- Patients who are 18 years or older with Heart Failure diagnosis as defined by internationally recognized guidelines.
- Current residents of the Hashemite Kingdom of Jordan
Key exclusion criteria (2 listed)
- Patients who refuse or unable to sign a consent form.
- Patient inability to follow up with provider
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| observationalHeart failure, non interventional | Other | – |
Primary outcome
Cardiovascular death
Time frame: 12 months
The main objective of the JoHFR is to obtain reliable estimate of rates of cardiovascular death and or hospitalization for decompensated heart failure
1 secondary outcome
worsening kidney function
Time frame: 12 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Jul 2024.
- Background: PubMed 32679282Joseph P, Dokainish H, McCready T, Budaj A, Roy A, Ertl G, Gomez-Mesa JE, Leong D, Ezekowitz J, Hage C, Lanas F, Maggioni AP, Sliwa K, Zhu J, Rouleau J, Balasubramanian K, Yusuf S; G-CHF Investigators. A multinational registry to study the characteristics and outcomes of heart failure patients: The global congestive heart failure (G-CHF) registry. Am Heart J. 2020 Sep;227:56-63. doi: 10.1016/j.ahj.2020.06.002. Epub 2020 Jun 6.
- Background: PubMed 30092697Savarese G, Vasko P, Jonsson A, Edner M, Dahlstrom U, Lund LH. The Swedish Heart Failure Registry: a living, ongoing quality assurance and research in heart failure. Ups J Med Sci. 2019 Jan;124(1):65-69. doi: 10.1080/03009734.2018.1490831. Epub 2018 Aug 9.
- Background: PubMed 27324686Crespo-Leiro MG, Anker SD, Maggioni AP, Coats AJ, Filippatos G, Ruschitzka F, Ferrari R, Piepoli MF, Delgado Jimenez JF, Metra M, Fonseca C, Hradec J, Amir O, Logeart D, Dahlstrom U, Merkely B, Drozdz J, Goncalvesova E, Hassanein M, Chioncel O, Lainscak M, Seferovic PM, Tousoulis D, Kavoliuniene A, Fruhwald F, Fazlibegovic E, Temizhan A, Gatzov P, Erglis A, Laroche C, Mebazaa A; Heart Failure Association (HFA) of the European Society of Cardiology (ESC). European Society of Cardiology Heart Failure Long-Term Registry (ESC-HF-LT): 1-year follow-up outcomes and differences across regions. Eur J Heart Fail. 2016 Jun;18(6):613-25. doi: 10.1002/ejhf.566.
- Background: PubMed 27301467Bergethon KE, Ju C, DeVore AD, Hardy NC, Fonarow GC, Yancy CW, Heidenreich PA, Bhatt DL, Peterson ED, Hernandez AF. Trends in 30-Day Readmission Rates for Patients Hospitalized With Heart Failure: Findings From the Get With The Guidelines-Heart Failure Registry. Circ Heart Fail. 2016 Jun;9(6):10.1161/CIRCHEARTFAILURE.115.002594 e002594. doi: 10.1161/CIRCHEARTFAILURE.115.002594.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Hadi M Abu-Hantash, MD,MSc study chair
Interventional Cardiovascular Innovation group
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Heart Failure and Chronic Heart Failure, run by Jordan Cardio Vascular Research Group at 1 site in Jordan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Jul 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Jordan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cardiovascular death (time frame: 12 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04829591, which also lists 4 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Jul 2024; AzTrials last refreshed its copy on 6 Nov 2026.