Clinical trials: Chronic Hemodialysis
Renal Insufficiency, Chronic, Anxiety
AI-Guided Personalized Relaxation for Hemodialysis Patients
Patients undergoing maintenance hemodialysis frequently experience impaired health-related quality of life, anxiety, and difficulties in coping with the long-term demands of treatment.
- Conditions
- Renal Insufficiency, Chronic, Anxiety, Relaxation Therapy, Maintenance Hemodialysis
- Trial name
- NCT07522944
- Testing
- AI-Guided Relaxation Platform, Standard Hemodialysis Nursing Care
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Alexandria University
Resistant Hypertension, Kidney Failure, Chronic
Low-Dose Spironolactone in Hemodialysis Patients With Resistant Hypertension
Many patients on hemodialysis have high blood pressure that does not respond to three or more drugs (resistant hypertension). This pilot study gave a low dose of spironolactone (12.5 mg once daily) for 6 weeks to adults on…
- Conditions
- Resistant Hypertension, Kidney Failure, Chronic, Hemodialysis
- Trial name
- NCT07888504
- Testing
- Spironolactone
- Where
- Indonesia
- Volunteers
- 21 people
- Sponsor
- Universitas Sebelas Maret
Depressive Disorders, End-stage Chronic Kidney Disease Treated With Hemodialysis
Evaluation of Depression Screening Methods Administered by Registered Nurses in Chronic Hemodialysis Patients
Hemodialysis is a vital replacement therapy for patients with end-stage chronic kidney disease, but it imposes a heavy, demanding, and prolonged management, associated with a significant deterioration in quality of life.
- Trial name
- IDE-3D (NCT07651436)
- Testing
- evaluate the psychometric performance of different modalities of hetero-assessment of depressive symptoms by nurses
- Where
- 2 sites in France
- Volunteers
- 450 people
- Sponsor
- Centre Hospitalier Annecy Genevois
End-stage Chronic Kidney Disease Treated With Hemodialysis, Depressive Disorders
Evaluation of the Effect of Light Therapy on the Evolution of Self-reported Depressive Disorders in Chronic Hemodialysis Patients
Hemodialysis is an intensive treatment, with a lifestyle dictated by the organization of the dialysis center. This treatment is associated with a decrease in quality of life, an increase in sleep disorders, and depressive…
- Trial name
- LUMIDIAL-2 (NCT07729358)
- Testing
- Light therapy using active glasses, Light therapy using inactive glasses
- Where
- France
- Volunteers
- 340 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Malnutitrion, Chronic Kidney Disease on Hemodialysis
Nutritional Status in Patients With Chronic Kidney Disease Receiving 7.2% Amino Acids During Hemodialysis
Malnutrition and anemia are common among people with chronic kidney disease who receive maintenance hemodialysis. These conditions may worsen health outcomes and quality of life.
- Conditions
- Malnutitrion, Chronic Kidney Disease on Hemodialysis, Anemia (Diagnosis)
- Trial name
- NCT07881627
- Where
- Indonesia
- Volunteers
- 90 people
- Sponsor
- PT Otsuka Indonesia
Sarcopenia, Chronic Kidney Disease
Egg Albumin and Agave Fructans With Exercise in Hemodialysis
Patients receiving maintenance hemodialysis frequently develop loss of muscle mass, reduced physical function, and chronic inflammation.
- Conditions
- Sarcopenia, Chronic Kidney Disease, Hemodialysis
- Trial name
- EAF-HD (NCT07877545)
- Testing
- HemProt, Functional Exercise Program
- Where
- Mexico
- Volunteers
- 66 people
- Sponsor
- Centenario Hospital Miguel Hidalgo
Chronic Kidney Disease (Stages 3b-5), Hemodialysis
Virtual Reality Versus Intradialytic Neuromuscular Electrical Stimulation on Renin Hormone in Chronic Kidney Patients
Worldwide accelerated advances in physical rehabilitation of chronic kidney disease; particularly whom undergoing hemodialysis. Multimodal therapeutic approaches may maximize their recovery through preliminary evidence indicating…
- Conditions
- Chronic Kidney Disease (Stages 3b-5), Hemodialysis, Shoulder Adhesive Capsulitis
- Trial name
- NCT07760285
- Testing
- Virtual Reality session, intradialytic neuromuscular electrical stimulation, Maitland Mobilization
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Adly A Adam
End Stage Renal Disease (ESRD), Kidney Failure
A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease
The goal of the CSP-2002 clinical trial is to evaluate the safety and effectiveness of the InnAVasc Arteriovenous Graft (IG) for hemodialysis (HD) access in patients with end-stage renal disease (ESRD).
- Conditions
- End Stage Renal Disease (ESRD), Kidney Failure, Chronic Renal Disease, Hemodialysis
- Trial name
- NCT04671771
- Testing
- InnAVasc Arteriovenous Graft (IG) surgical implant
- Where
- 22 sites in United States
- Volunteers
- 133 people
- Sponsor
- W.L.Gore & Associates
Complication of Renal Dialysis, End Stage Renal Disease
A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery
The primary study objective is to evaluate the benefit of the Sirolimus eluting Collagen implant (SeCI; Sirogen), a single dose prophylactic treatment delivered intraoperatively at the time of surgical creation of an…
- Conditions
- Complication of Renal Dialysis, End Stage Renal Disease, End Stage Kidney Disease, ESRD
- Trial name
- ACCESS2 (NCT05425056)
- Testing
- Sirolimus
- Where
- 22 sites in United States, United Kingdom
- Volunteers
- 136 people
- Sponsor
- Vascular Therapies, Inc.
Chronic Kidney Disease (CKD), Hemodialysis Complication
ESA Hyporesponsiveness in Hemodialysis Patients
This prospective cohort study aims to evaluate the development, persistence, and recovery of erythropoiesis-stimulating agent (ESA) hyporesponsiveness among patients receiving maintenance hemodialysis.
- Conditions
- Chronic Kidney Disease (CKD), Hemodialysis Complication, Anemia
- Trial name
- NCT07855458
- Volunteers
- 200 people
- Sponsor
- Assiut University
Chronic Kidney Disease Requiring Hemodialysis, End-Stage Kidney Disease (ESKD)
DIALysis With EXpanded Solute Removal
The goal of this clinical trial is to evaluate the health effects of expanded hemodialysis in patients receiving hemodialysis. The main question it aims to answer is: 1) Does expanded hemodialysis reduce the risk of death from…
- Conditions
- Chronic Kidney Disease Requiring Hemodialysis, End-Stage Kidney Disease (ESKD), Chronic Kidney Disease Requiring Chronic Dialysis, Pragmatic Randomized Controlled Trial
- Trial name
- DIALEX (NCT06660277)
- Testing
- Super High-Flux Dialyzer, High-Flux Dialyzer
- Where
- 3 sites in Canada
- Volunteers
- 4,800 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chatbot-Based Training, Hemodialysis
DialysisBot: AI Chatbot for Hemodialysis Self-Management
End-stage kidney disease requiring hemodialysis is a chronic condition with substantial clinical, functional, and psychosocial burden.
- Conditions
- Chatbot-Based Training, Hemodialysis, Self-management
- Trial name
- NCT07830810
- Testing
- DialysisBot
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Rome Tor Vergata
Chronic Kidney Disease; End-Stage Renal Disease; Hemodialysis; Pain; Anxiety
Deep Breathing Relaxation and Lemongrass Aromatherapy on Pain
This randomized controlled trial aims to evaluate the effect of deep breathing relaxation combined with lemongrass aromatherapy on pain during arteriovenous fistula needle insertion and anxiety in hemodialysis patients.
- Trial name
- NCT07825974
- Testing
- Deep Breathing Relaxation, Lemongrass Aromatherapy
- Where
- Iraq
- Volunteers
- 190 people
- Sponsor
- University of Baghdad
Chronic Kidney Disease, End Stage Renal Disease
Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans
This study is intended to correct an important systemic deficit in the care of chronic kidney disease (CKD), VHA's fourth most common healthcare condition with high mortality and healthcare burden.
- Conditions
- Chronic Kidney Disease, End Stage Renal Disease, Hemodialysis, Peritoneal Dialysis
- Trial name
- TEACH-VET (NCT04064086)
- Testing
- Comprehensive Pre-ESRD Patient Education (CPE), Provision of the freely available resources for Kidney Disease Education
- Where
- United States
- Volunteers
- 656 people
- Sponsor
- VA Office of Research and Development
Chronic Kidney Disease on Hemodialysis, Physical Exercise Behavior (Liking/Aversion)
Physical Exercise in Patients With Chronic Kidney Disease in Hemodialysis (Pehedal-ESKD)
The goal of this clinical trial is to learn whether different types of exercise performed during hemodialysis are safe, well tolerated, and beneficial for adults receiving maintenance hemodialysis.
- Trial name
- Pehedal-ESKD (NCT07820514)
- Testing
- Intradialytic aerobic exercise using a cycle ergometer, Intradialytic elastic-band resistance exercise
- Where
- Italy
- Volunteers
- 312 people
- Sponsor
- Ricerca Nefrocenter
End Stage Kidney Disease (ESKD), Hemodialysis
Medium Cut-Off and High-Flux Membranes on Mineral and Bone Metabolism in Hemodialysis Patients
This study aims to compare the effects of medium cut-off (MCO) and high-flux hemodialysis membranes on mineral and bone metabolism biomarkers in patients receiving maintenance hemodialysis.
- Conditions
- End Stage Kidney Disease (ESKD), Hemodialysis, Chronic Kidney Disease Mineral and Bone Disorder
- Trial name
- MBD-HD (NCT07685223)
- Testing
- Medium Cut-Off Hemodialysis Membrane, High-Flux Hemodialysis Membrane
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gazi University
End-Stage Kidney Disease (ESKD), Hemodialysis
Cardiovascular and Bone Mineral Markers in Dialysis Patients and Healthy Controls
This observational study will compare cardiovascular status, bone mineral metabolism, systemic inflammation, body composition, functional status, quality of life, pruritus, and pain among patients receiving different renal…
- Conditions
- End-Stage Kidney Disease (ESKD), Hemodialysis, Peritoneal Dialysis (PD)
- Trial name
- NCT07686978
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gazi University
Hemodialysis, End Stage Chronic Renal Failure
Mindfulness for Saudi Hemodialysis Patients
This study aims to evaluate whether an MBI improves sleep quality, emotional symptoms (depression, anxiety, stress), emotion regulation, and trait mindfulness among adults with ESRD on HD.
- Trial name
- MSHP (NCT07816354)
- Testing
- Mindfulness-Based Intervention
- Where
- Saudi Arabia
- Volunteers
- 38 people
- Sponsor
- Jordan University of Science and Technology
Chronic Kidney Disease (Stages 4 and 5), Hemodialysis
Inspiratory Muscle Training During Hemodialysis
This study will evaluate whether inspiratory muscle training performed during hemodialysis improves inspiratory muscle strength in adults receiving regular hemodialysis.
- Conditions
- Chronic Kidney Disease (Stages 4 and 5), Hemodialysis, Inspiratory Muscle Training
- Trial name
- RespDialysis (NCT07811947)
- Testing
- Inspiratory Muscle Training, Usual Care
- Where
- Portugal
- Volunteers
- 53 people
- Sponsor
- Tecsam - Tecnologia e Servicos Medicos
End Stage Kidney Disease (ESKD), Hemodialysis
Randomized Cross-Over Comparison of Medium Cut-Off and High-Flux Hemodialysis Membranes
Patients receiving maintenance hemodialysis are at increased risk of cardiovascular disease, chronic inflammation, endothelial dysfunction, and impaired quality of life.
- Conditions
- End Stage Kidney Disease (ESKD), Hemodialysis, Cardiovascular Diseases (CVD), Inflammation
- Trial name
- MCO-HD (NCT07679763)
- Testing
- Medium Cut-Off Hemodialysis Membrane, High-Flux Hemodialysis Membrane
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gazi University