Clinical trials: Chronic Hypersensitivity Pneumonitis
Hypersensitivity Pneumonitis
Evaluation of the Efficacy of Pirfenidone in Progressive Chronic Hypersensitivity Pneumonitis
This study aims to evaluate the efficacy of pirfenidone in chronic hypersensitivity pneumonitis. This study included 40 adult patients (≥ 18 years) with a diagnosis of chronic progressive hypersensitivity pneumonitis.
- Trial name
- NCT04675619
- Testing
- Oral pirfenidone, Standard care
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Zagazig University
Hypersensitivity Pneumonitis
A Prognostic Transcriptomic Signature for Chronic Hypersensitivity Pneumonitis
Up to 150 patients with hypersensitivity pneumonitis will be enrolled at 7 clinical centers across the United States. Patients will be followed for 24 months to determine if biomarkers in the blood can predict disease progression.
- Trial name
- PREDICT-HP (NCT04844359)
- Where
- 7 sites in United States
- Volunteers
- 137 people
- Sponsor
- National Jewish Health
Pulmonary Fibrosis
Supplemental Oxygen in Pulmonary Fibrosis
To enhance understanding of supplemental oxygen-its utility in and adoption by patients with pulmonary fibrosis-by examining how patients perceive it and by determining how perceptions and patient-centered outcome measures change…
- Trial name
- NCT01961362
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
Hypersensitivity Pneumonitis, Chronic Hypersensitivity Pneumonitis
Assessing Health Related Quality of Life in Hypersensitivity Pneumonitis
The objective of this study is to administer and validate a disease specific health related quality of life (HRQOL) survey for patients with Chronic Hypersensitivity Pneumonitis (CHP).
- Conditions
- Hypersensitivity Pneumonitis, Chronic Hypersensitivity Pneumonitis, Interstitial Lung Disease, Extrinsic Allergic Alveolitis
- Trial name
- CHP-HRQOL (NCT04273867)
- Testing
- Chronic Hypersensitivity Pneumonitis Health Related Quality of Life Survey Instrument
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Weill Medical College of Cornell University
Chronic Respiratory Diseases, Cystic Fibrosis
Breath Analysis and Arterial Stiffness in Patients With Respiratory Diseases
Assessment of cardiovascular disorders using echocardiography and arterial stiffness; comparative noninvasive assessment of volatile organic compound (eVOC) exhale breath patterns in patients with different chronic respiratory…
- Conditions
- Chronic Respiratory Diseases, Cystic Fibrosis, Lymphangioleiomyomatosis, Hypersensitivity Pneumonitis
- Trial name
- NCT05727852
- Testing
- Breath test using the Compact PTR-TOF-MS, Portable cardiac monitor "CardioQvark", Assessment of arterial stiffness using the VaSera VS-1500N
- Where
- Russia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Interstitial Lung Disease
Gabapentin vs. Benzonatate vs. Standard of Care for Cough in ILD
Absence of a clear standard of care and approved drug for chronic cough, the commonest symptom in ILD, calls for further research in this area.
- Trial name
- GAZEBO-ILD (NCT07859839)
- Testing
- Gabapentin, Benzonatate 200 mg, Standard of care treatment for ILD
- Where
- India
- Volunteers
- 177 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Interstitial Lung Disease, Pulmonary Fibrosis
P4O2 ILD Extension
The goal of this observational study is to identify early biomarkers that can predict the development of progressive pulmonary fibrosis (PPF) in participants with interstitial lung diseases (ILDs).
- Conditions
- Interstitial Lung Disease, Pulmonary Fibrosis, Interstitial Lung Fibrosis, IPF
- Trial name
- P4O2-ILD (NCT06644144)
- Testing
- No Interventions
- Where
- Netherlands
- Volunteers
- 450 people
- Sponsor
- Amsterdam UMC, location VUmc
Hypersensitivity Pneumonitis, Extrinsic Allergic Alveolitis
Pulmonary Rehabilitation in Patients With Chronic Fibrotic Hypersensitivity Pneumonitis
The aim is to evaluate exercise capacity, respiratory functions, respiratory and peripheral muscle strength, inspiratory muscle endurance, physical activity level, quality of life, fatigue, dyspnea, anxiety, depression and…
- Trial name
- NCT04561479
- Testing
- Pulmonary Rehabilitation, Alternative Exercises
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Pulmonary Fibrosis of Any Cause, Primary Supporters/Caretakers of Patients With Pulmonary Fibrosis
Pulmonary Fibrosis Contact Registry
As the name states, contact registries securely store contact information from groups of reasonably well-characterized patients (or primary supporters/caregivers) who are interested in being informed about ongoing or future…
- Trial name
- NCT01935726
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis
Toward Self-management in ILD
Treating and caring for people with long term conditions accounts for a substantial proportion of health care resources. Self-management is advocated as a mechanism that can empower service users with long term conditions to…
- Conditions
- Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Connective Tissue Related ILD, Chronic Hypersensitivity Pneumonitis
- Trial name
- NCT03300583
- Testing
- Focus groups, Semi-structured interviews
- Where
- 2 sites in United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kingston University
Interstitial Lung Disease Due to Systemic Disease (Disorder), Interstitial Lung Disease Due to Systemic Disease (Telomere Biology Disorder)
Occupational and Environmental Exposures Analysis in Interstitial Lung Diseases.
The OCEAN-ILD study is designed to prospectively evaluate the prevalence and clinical relevance of environmental and occupational exposures in a large Italian cohort of patients affected by any ILD, using a standardised exposure…
- Conditions
- Interstitial Lung Disease Due to Systemic Disease (Disorder), Interstitial Lung Disease Due to Systemic Disease (Telomere Biology Disorder), Exposure Occupational, Occupational Exposure
- Trial name
- OCEAN-ILD (NCT07577115)
- Testing
- standard interview
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Istituto Clinico Humanitas
Pulmonary Fibrosis, Progressive Pulmonary Fibrosis
A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis
A randomized, double-blind, placebo-controlled clinical study to evaluate the safety and efficacy of 2 doses of inhaled pirfenidone (AP01) versus placebo on top of standard of care in participants with PPF over 52 weeks.
- Conditions
- Pulmonary Fibrosis, Progressive Pulmonary Fibrosis, Pulmonary Fibrosis Secondary to Systemic Sclerosis, Pulmonary Fibrosis, Interstitial Lung Disease
- Trial name
- NCT06329401
- Testing
- AP01
- Where
- 154 sites in United States, Argentina and 12 more
- Volunteers
- 398 people
- Sponsor
- Avalyn Pharma Inc.
Alveolitis Extrinsic Allergic, Pulmonary Fibrosis
Pirfenidone in the Chronic Hypersensitivity Pneumonitis Treatment
The Chronic Hypersensitivity Pneumonitis (HP), is an inflammatory disease who has an evolution to develop progressive interstitial fibrosis, who cause the death of the patient.
- Trial name
- Picheon (NCT02496182)
- Testing
- Pirfenidone
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Grupo Medifarma, S. A. de C. V.
Hypersensitivity Pneumonitis, Airway Disease Small
Small Airway Involvement in Patients With Chronic Hypersensitivity Pneumonitis
Hypersensitivity pneumonitis (HP) is a syndrome with variable clinical presentation in which lung inflammation is caused by inhalation of specific organic antigens or low molecular weight particles in previously sensitized…
- Trial name
- NCT02523833
- Testing
- Salbutamol
- Where
- Brazil
- Volunteers
- 27 people
- Sponsor
- University of Sao Paulo General Hospital
Hypersensitivity Pneumonitis, Nasal Mucosal Disorder
Study of Nasal Mucosa Histopathological Changes in Chronic Hypersensitivity Pneumonitis
Background:Hypersensitivity pneumonitis (HP) is an interstitial lung disease that develops after inhalation of organic or inorganic antigens in susceptible individuals.
- Trial name
- NCT05723796
- Testing
- nasal endoscopy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University