Clinical trials: Chronic Hypertension
Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Prognostic Value of Estimated Plasma Volume in Pulmonary Hypertension
Assessment of the prognostic value of the estimation of plasma volume or its variation in patients with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH) after acute right heart…
- Conditions
- Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Acute Right Heart Failure
- Trial name
- NCT05861479
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Pulmonary Hypertension, Pulmonary Arterial Hypertension
Pulmonary Hypertension Biorepository and Registry
Establish a pulmonary hypertension registry and biorepository to lead towards a further understanding of the disease.
- Conditions
- Pulmonary Hypertension, Pulmonary Arterial Hypertension, Pulmonary Hypertension Due to Left Heart Disease, Pulmonary Hypertension, Primary
- Trial name
- PHBR (NCT04808596)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Kansas Medical Center
Essential Hypertension, Chronic Stable Angina
Observational Study to Evaluate the Safety of DILATREND SR Cap. in Korean Patients With Essential Hypertension, Chronic Stable Angina and Congestive Heart Failure
The purpose of this study is to Evaluate the Safety of DILATREND SR Cap. in Korean Patients with Essential hypertension, Chronic stable angina and Congestive heart failure for 52 weeks.
- Conditions
- Essential Hypertension, Chronic Stable Angina, Congestive Heart Failure
- Trial name
- DELIGHT (NCT03063697)
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Hypertension, Hypertension Complicated With Type 2 Diabetes
Effects of Different Training Programs in Chronic Disease Patients
The study is a randomized 3-month community-based exercise intervention with a control group and 2 different exercise groups: walking group and Chinese square dancing group.Eighteen communities will be selected in Beijing, and…
- Conditions
- Hypertension, Hypertension Complicated With Type 2 Diabetes, Walking, Chinese Square Dancing
- Trial name
- NCT03785886
- Testing
- Walking group, Chinese square dancing group, Control group
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Beijing Sport University
Hypertension, Diabetes
mWELLCARE:An Integrated mHealth System for the Prevention and Care of Chronic Disease
Major barriers to controlling cardiovascular diseases (CVDs) in India and elsewhere are: low detection rates, inadequate use of evidence based interventions and low adherence with these interventions.
- Conditions
- Hypertension, Diabetes, Depression, Alcohol Use Disorder
- Trial name
- mWELLCARE (NCT02480062)
- Testing
- mWELLCARE, Usual Care
- Where
- 40 sites in India
- Volunteers
- 3,702 people
- Sponsor
- Public Health Foundation of India
Pulmonary Hypertension, Pulmonary Hypertension Chronic Thromboembolic
Medication Reconciliation in Pulmonary Hypertension
Pulmonary hypertension (PH) is a life threatening condition. In PH, pulmonary arterial hypertension (PAH) and chronic thrombo-embolic chronic pulmonary hypertension (CTEPH) are two rare diseases requiring specific and complex…
- Conditions
- Pulmonary Hypertension, Pulmonary Hypertension Chronic Thromboembolic, Pulmonary Arterial Hypertension
- Trial name
- OPTICARE-HTP (NCT04744584)
- Testing
- Medication reconciliation
- Where
- France
- Volunteers
- 129 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypertension, CKD - Chronic Kidney Disease
A Randomized Trial of Six-Channel RF Ablation System for Renal Denervation in Uncontrolled Hypertension and Chronic Kidney Disease
Prospective, Multi-Center, Randomized, Parallel-Controlled, Uptake clinical trial to evaluate the efficacy and safety of the six-channel radiofrequency（RF) renal denervation system-comprising the six-channel radiofrequency…
- Trial name
- NCT07130955
- Testing
- Six-channel RF Renal Denervation System
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Shanghai Golden Leaf MedTec Co. Ltd
Chronic Thromboembolic Pulmonary Hypertension
Balloon Pulmonary Angioplasty in Non-operable CTEPH Patients
Balloon pulmonary angioplasty (BPA) emerged as a potential therapeutic option for non-operable patients with chronic thromboembolic pulmonary hypertension (CTEPH).
- Trial name
- NCT02964390
- Testing
- Balloon Pulmonary Angioplasty
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Department of Pulmonary Circulation and Thromboembolic Diseases, Medical Center for Postgraduate Med
Chronic Kidney Diseases, Hypertension
Remote Ischaemic Conditioning on Blood Pressure Control in Chronic Kidney Disease Patients
Chronic kidney disease (CKD) is one of the leading causes of death and disability in Singapore and worldwide. Hypertension is commonly inadequately controlled in patients with CKD and this is associated with CKD progression and…
- Conditions
- Chronic Kidney Diseases, Hypertension, Cardiovascular Diseases
- Trial name
- ERIC-BP-CKD (NCT03236350)
- Testing
- Active autoRIC® (CRIC Treatment)
- Where
- Singapore
- Volunteers
- 85 people
- Sponsor
- Singapore General Hospital
Hypertension, Menopause
Effects of Different Exercises Interventions in Post-menopausal Women
This study will compare different exercise training protocols on health parameters of postmenopausal women. The hypothesis is that short duration high intensity interval training will promote different effects of long duration…
- Trial name
- NCT03942276
- Testing
- High intensity interval training, Moderate intensity continuous training, Control
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Uberlandia
Hypertension, Chronic Stable Angina
Bioequivalency Study of Amlodipine Tablets Under Fasting Conditions
The objective of this study was the bioequivalence of a Roxane Laboratories' Amlodipine Besylate tablets, 10 mg, to Norvasc® Tablets, 10 mg (Pfizer) under fasting conditions using a single-dose, randomized, 2-treatment, 2-period…
- Conditions
- Hypertension, Chronic Stable Angina, Vasospastic Angina
- Trial name
- NCT00602017
- Testing
- Amlodipine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Hypertension, Diabetes
Development and Testing of a Sub-district Specific Model of 'Whole-of-government', and 'Whole-of-society' Approaches for the Prevention and Control of Non-communicable Diseases in a Sub-district of Bangladesh
Globally, non-communicable diseases (NCDs) are the leading cause of both mortality and morbidity. This intervention study aims to prevent and manage NCDs by adopting the World Health Organization's (WHO) comprehensive…
- Conditions
- Hypertension, Diabetes, Asthma, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT06453382
- Testing
- Behavioural change modification, Screening, NCD related knowledge practice and attitude
- Where
- Bangladesh
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- BRAC University
Pulmonary Embolism, Pulmonary Hypertension
Ventilation and Perfusion Scan in Pulmonary Embolism Following Catheter Directed Thrombectomy Versus Anticoagulation Alone
Clinical presentation of acute pulmonary embolism (PE) is complex and varied and not uncommonly involves respiratory failure with dyspnea or hypoxia.
- Conditions
- Pulmonary Embolism, Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Hypertension
- Trial name
- VQPE (NCT05133713)
- Testing
- Catheter directed therapy, Systemic anticoagulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Arizona
Hepatitis C
Macrophages, Portal Hypertension, and Liver Function During AbbVie Treatment of Chronic Hepatitis C
Investigation of the effects of the new Abbvie direct acting anti-viral (DAA) treatment of chronic viral hepatitis C infection on the macrophage specific activation marker soluble CD163, portal hypertension determined by the…
- Trial name
- NCT02526641
- Testing
- Functional Hepatic Nitrogen Clearance (FHNC), Galactose Elimination Capacity (GEC), Liver vein catheterization
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- University of Aarhus
COVID-19, Long COVID
Using Data From a Multisensor Rapid Health Assessment Device to Predict Decompensation in Long COVID (AIDI)
We are conducting a research study at the VA hospital in Bedford, MA to learn more about how a multisensor rapid health assessment device, MouthLab, can help predict or anticipate future health complications in patients with…
- Trial name
- AIDI (NCT05713266)
- Testing
- MouthLabTM
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Edith Nourse Rogers Memorial Veterans Hospital
Chronic Liver Disease (CLD), Liver Cirrhosis
Heart Problems in Children With Chronic Liver Disease
Chronic liver disease (CLD) in children can sometimes lead to complications in other parts of the body, including the heart. The primary purpose of this observational study is to assess the presence and type of cardiac problems…
- Conditions
- Chronic Liver Disease (CLD), Liver Cirrhosis, Cardiac Abnormalities, Portopulmonary Hypertension
- Trial name
- NCT07502196
- Volunteers
- 60 people
- Sponsor
- Assiut University
Interstitial Lung Disease, COPD
Pulmonary Hypertension SOLAR
The main goal of this study is to develop a noninvasive signature for pulmonary vascular remodeling in Group 3 PH patients, using hyperpolarized 129Xe magnetic resonance imaging (129Xe MRI).
- Conditions
- Interstitial Lung Disease, COPD, Pulmonary Arterial Hypertension
- Trial name
- PH SOLAR (NCT04778046)
- Testing
- Hyperpolarized 129Xe
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Bastiaan Driehuys
Cardiorenal Metabolic Syndrome, Atherosclerotic Cardiovascular Disease
Effect of Secukinumab on Cardiorenal Outcomes in Patients With Cardiorenal Metabolic Syndrome and Atherosclerotic Cardiovascular Disease
This is a prospective, randomized, open-label, parallel-controlled clinical trial to evaluate the efficacy and safety of targeted IL-17A inhibition with secukinumab on cardiovascular and renal endpoints in 100 patients with…
- Conditions
- Cardiorenal Metabolic Syndrome, Atherosclerotic Cardiovascular Disease, Chronic Kidney Disease, Coronary Artery Disease
- Trial name
- NCT07704190
- Testing
- Secukinumab (75 mg), Standard Medical Therapy
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Type 2 Diabetes Mellitus (T2DM), Hypertension
Eating Window and Sleep Disorders on Glycemic Control, Cardiovascular Risk, and Weight Loss
This project aims to offer a quantitative and qualitative nutritional approach, along with educational nutritional guidelines for participants with Non-Communicable Chronic Diseases.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Hypertension, Obesity and Type 2 Diabetes, Cardiovascular Diseases
- Trial name
- NCT06735859
- Testing
- Comparison of eating windows intervention
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Chronic Thromboembolic Pulmonary Hypertension, Inspiratory Muscle Training
Inspiratory Muscle Training in Pulmonary Hypertension
Inspiratory muscle training for 8 weeks in patients with pulmonary hypertension.
- Conditions
- Chronic Thromboembolic Pulmonary Hypertension, Inspiratory Muscle Training, Inspiratory Muscle Weakness, Pulmonary Arterial Hypertension
- Trial name
- NCT03102294
- Testing
- inspiratory muscle training
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Federal University of São Paulo
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