Clinical trials: Chronic Ischaemic Heart Disease
Cardiovascular Diseases, Heart Diseases
The Jackson Heart Study of Cardiovascular Disease Among African Americans
This is a prospective study of the environmental and genetic factors that influence the development of cardiovascular disease (CVD) in African American adults.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis, Coronary Disease
- Trial name
- JHS (NCT00005485)
- Where
- United States
- Volunteers
- 5,306 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Total Occlusion, Coronary Artery Disease
STENTYS Xposition S in the Treatment of Chronic Total Artery Occlusion
Intro: Chronic total occlusions (CTO) are the most severe coronary lesions. Negative distal vessel remodeling occurs in these lesions, leading to reduction of artery diameter.
- Trial name
- SXS-CTO (NCT03563989)
- Testing
- Implantation of Stent (PCI)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Ischemic Left Ventricular Dysfunction, Myocardial Infarction
The TRansendocardial Stem Cell Injection Delivery Effects on Neomyogenesis STudy (The TRIDENT Study)
Thirty (30) patients with chronic ischemic left ventricular dysfunction secondary to MI scheduled to undergo cardiac catheterization will be enrolled in the study.
- Trial name
- Trident (NCT02013674)
- Testing
- Allogeneic hMSCs
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Joshua M Hare
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Insomnia, Insomnia Chronic
SHADES Mechanistic Trial
Cardiovascular disease (CVD) is common, deadly, and costly, and adults with insomnia represent a large group of people at elevated risk of developing CVD in the future.
- Conditions
- Insomnia, Insomnia Chronic, Insomnia, Primary, Sleep Disturbance
- Trial name
- SHADES (NCT06041581)
- Testing
- Sleep Healthy Using The Internet (SHUTi), Telephonic CBT-I, Face-to-Face CBT-I
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Stable Chronic Angina
Impact of Stent Length on Short Term Outcomes in Patients With Stable Coronary Disease Undergoing PCI
Impact of stent length on short term outcomes in patients with stable coronary artery disease undergoing PCI
- Trial name
- NCT03911895
- Testing
- Stent more than 26 mn length, Stent equal to or less than26 mn length
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Assiut University
Acute Myocardial Infarction
Hair Cortisol and Testosterone Levels in Patients With and Without Acute Myocardial Infarction(MI)
The purpose of this study is to determine whether hair levels of cortisol and testosterone are elevated in patients with acute MI compared to controls.
- Trial name
- NCT01144065
- Testing
- Hair sampling for the measurement of cortisol and testosterone
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Meir Medical Center
Chronic Heart Failure, Coronary Heart Disease (CHD)
Real-World Effectiveness and Costs of Yiqi Fumai Lyophilized Injection in Coronary Heart Disease-Related Chronic Heart Failure
This two-center retrospective cohort study will use de-identified electronic health records from June 1, 2021 through June 1, 2026 to compare patients with coronary heart disease-related chronic left ventricular dysfunction or…
- Trial name
- NCT07841275
- Testing
- Yiqi Fumai Lyophilized Injection
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- China Academy of Chinese Medical Sciences
Ischaemic Heart Disease, Coronary Heart Disease
Liraglutide to Improve corONary Haemodynamics During Exercise streSS
A single-centre double-blind placebo-controlled crossover randomised controlled trial to determine the physiological basis of glucagon-like peptide-1 receptor activation on exercise haemodynamics, as manifest through specific…
- Conditions
- Ischaemic Heart Disease, Coronary Heart Disease, Chronic Stable Angina
- Trial name
- LIONESS (NCT02315001)
- Testing
- Liraglutide
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- King's College London
Heart Failure, Congestive
Effect of 48 Hours of Treatment With the Natural Peptide-Hormone GLP-1 in Patients With Chronic Heart Failure
The purpose of this study is to determine whether 48 hours of glucagon-like-peptide-1 (GLP-1) infusion can improve heart function and alter substrate metabolism in non-diabetic patients with heart failure.
- Trial name
- NCT00264199
- Testing
- GLP-1
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Aarhus University Hospital Skejby
Renal Insufficiency, Chronic, Angioplasty, Transluminal, Percutaneous Coronary
Iodixanol vs. Iomeprol to Prevent Contrast-Induced Nephropathy After Coronary Intervention (CONTRAST)
The purpose of this study is to demonstrate that Iodixanol 320 is associated with a lower incidence of contrast-induced nephropathy (CIN) when compared with hyperosmolar contrast medium Iomeprol 350 in patients with impaired…
- Conditions
- Renal Insufficiency, Chronic, Angioplasty, Transluminal, Percutaneous Coronary, Coronary Arteriosclerosis
- Trial name
- NCT00390585
- Testing
- Iodixanol 320, Iomeprol 350
- Where
- 2 sites in Germany
- Volunteers
- 324 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Coronary Artery Disease
Abrupt Versus Tapered Interruption of Chronic Clopidogrel Therapy After DES Implantation
The hypothesis to be tested is that gradual clopidogrel therapy cessation is associated with a superior clinical outcome compared with abrupt cessation (superiority hypothesis).
- Trial name
- ISAR-CAUTION (NCT00640679)
- Testing
- Abrupt Clopidogrel Interruption, Clopidogrel Tapering
- Where
- 2 sites in Germany
- Volunteers
- 782 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Chronic Stable Coronary Artery Disease
Syndrome Differentiation in the Management of Chronic Stable Coronary Artery Disease (SCAD) to Improve Quality
1.1 To build a TCM diagnosis and treatment database for chronic stable CAD; 1.2 To summarize the pattern of TCM medicine used and the effect of the medication in chronic stable CAD.
- Trial name
- NCT03018769
- Testing
- Chinese Herb
- Where
- 32 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Chronic Coronary Insufficiency, Coronary Artery Disease
Microcirculatory Status After Intravascular Lithotripsy
Due to differences in the mechanism of action, intravascular lithotripsy is likely to cause less distal embolization and microcirculatory dysfunction during plaque preparation.
- Trial name
- MARVEL (NCT05134051)
- Testing
- Shockwave® Intravascular Lithotripsy System (Shockwave Medical Inc)
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Cardiac Research Institute BV
Coronary Disease, Diabetes Mellitus, Non-Insulin-Dependent
Effects of Reiki on Painful Neuropathy and Cardiovascular Risk Factors
The object of this study is to determine if Reiki will improve glycemic control and cardiac autonomic function diabetic patients with painful neuropathy.
- Trial name
- NCT00010751
- Testing
- Reiki
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Rheumatoid Arthritis, Atherosclerotic Ischemic Disease
Coronary Computed Tomography Angiography In Rheumatoid Arthritis Study
The Coronary Computed Tomography Angiography in Rheumatoid Arthritis study is part of the multinational, prospective, observational Autoimmunity and Atherosclerosis in Rheumatic Diseases cohort (https://atacc-rd.com) that…
- Conditions
- Rheumatoid Arthritis, Atherosclerotic Ischemic Disease, Pulmonary Disease, Depressive Disorder
- Trial name
- COTIRA (NCT07363980)
- Where
- 4 sites in Denmark
- Volunteers
- 4,000 people
- Sponsor
- Ellen Margrethe Hauge
Angina Pectoris, Diabetes Mellitus, Type 2
Study Protocol for Rosiglitazone Versus Gliclazide in Diabetics With Angina
The principle objective of the trial is to compare rosiglitazone to gliclazide in patients with type 2 diabetes mellitus and chronic stable angina to see how the subjects' angina status changes.
- Trial name
- NCT00225342
- Testing
- Rosiglitazone, Gliclazide (Comparison drug)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Glasgow
Chronic Stable Angina
Management of Ischemic Heart Disease With Angiwell-XR (Ranolazine)
The rationale of MIDA trial is to determine efficacy and tolerability of ranolazine molecule among Pakistan population and obtain firsthand knowledge about the molecule ranolazine.
- Trial name
- MIDA (NCT03486561)
- Testing
- Ranolazine
- Volunteers
- 2,000 people
- Sponsor
- OBS Pakistan
Coronary Artery Disease
the Effect of Febuxostat on Coronary Plaque Volume in Patients With Chronic Stable Angina and Hyperuricemia
The purpose of this study is to investigate the effects of febuxostat on coronary plaque volume in patients with chronic stable angina and hyperuricemia.
- Trial name
- NCT02279342
- Testing
- Febuxostat
- Where
- Japan
- Volunteers
- 1 people
- Sponsor
- Yokohama City University Medical Center
Acute Coronary Syndrome, Chronic Kidney Disease
Platelet Resistance With Ticagrelor or Standard-Dose Clopidogrel Among CKD and ACS Patients
A 4 week-duration cross-over study on Ticagrelor and Clopidogrel for the Acute Coronary Syndrome (ACS) and Chronic Kidney Disease (CKD) subjects, focusing on the platelet inhibition and safety observation.
- Conditions
- Acute Coronary Syndrome, Chronic Kidney Disease, End-Stage Renal Disease
- Trial name
- APROVE-CKD (NCT02459288)
- Testing
- Clopidogrel first, Ticagrelor first
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Ping-Yen Liu