Clinical trials: Chronic Kidney Disease (CKD) Stage 5
Type 2 Diabetes, Chronic Kidney Disease (CKD) Stages G2 to G3b
A Study to Learn More About How Well Finerenone Works in Real-world in People With Type 2 Diabetes and Chronic Kidney Disease in Primary Care (IMSS= Instituto Mexicano Del Seguro Social)
The main purpose of this study is to learn how treatment with finerenone affects the urinary albumin-to-creatinine ratio (uACR), a marker of kidney health, over time in adults with type 2 diabetes and chronic kidney disease who…
- Trial name
- FINE-IMSS-MX (NCT07841015)
- Testing
- Finerenone
- Where
- Mexico
- Volunteers
- 800 people
- Sponsor
- Bayer
CKD (Chronic Kidney Disease) Stage 5D
ASPIrin in Reducing Events in Dialysis ( ASPIRED )
People with kidney failure requiring dialysis have a much higher risk of developing cardiovascular (CV) disease compared with the general population.
- Trial name
- NCT04381143
- Testing
- Aspirin 100 mg Oral Tablet
- Where
- 127 sites in China
- Volunteers
- 9,082 people
- Sponsor
- Guangdong Provincial People's Hospital
CKD, Chronic Kidney Disease (Stages 3b-5)
Fostering Self-Empowerment in CKD Patients Through Food Choice Mapping
This project aims to develop mapping of food choices available for chronic kidney disease (CKD) patients when dining out in Singapore.
- Trial name
- NCT07804316
- Testing
- Mobile application empowerment approach
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore Institute of Technology
End Stage Renal Disease (ESRD), Chronic Kidney Disease (CKD)
Clinical Effectiveness and Resource Use in End-Stage Renal Disease Patients: Remote Patient Monitoring Across Dialysis Modalities
This is a multicenter, prospective, observational real-world study designed to evaluate clinical effectiveness, quality of life, and healthcare resource utilization in patients with end-stage renal disease (ESRD) initiating…
- Trial name
- NCT07781124
- Testing
- Remote patient monitoring-automated peritoneal (RPM-APD), Manual peritoneal dialysis (PD) cohort, Maintenance hemodialysis (HD)
- Where
- 20 sites in China
- Volunteers
- 750 people
- Sponsor
- Vantive Health LLC
Chronic Kidney Disease (CKD) Stage 5, Kidney Dysfunction Requiring Dialysis (KDRD)
Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets)
In this pragmatic clinical trial, which will dovetail with Veterans' routine outpatient dialysis clinic visits in six VA medical centers, the investigators will study 252 Veterans with kidney disease who need to start dialysis…
- Conditions
- Chronic Kidney Disease (CKD) Stage 5, Kidney Dysfunction Requiring Dialysis (KDRD), Dialysis Dependency
- Trial name
- INCHVETS (NCT05465044)
- Testing
- Twice-weekly hemodialysis with incremental crossover to thrice-weekly schedule, Thrice-Weekly Hemodialysis
- Where
- 8 sites in United States
- Volunteers
- 252 people
- Sponsor
- VA Office of Research and Development
Kidney Transplant, Rejection of Renal Transplant
Development and Validation of HistoMX, a Gene-Expression Platform for Molecular Interpretation of Kidney Allograft Biopsies
This retrospective multicentre observational study developed and validated HistoMX, an automated gene-expression-based platform for multidimensional molecular interpretation of kidney allograft biopsies.
- Conditions
- Kidney Transplant, Rejection of Renal Transplant, Antibody Mediated Rejection, BK Virus Nephropathy
- Trial name
- HistoMX (NCT07700563)
- Volunteers
- 2,410 people
- Sponsor
- Paris Translational Research Center for Organ Transplantation
End-Stage Kidney Disease (ESKD), Chronic Kidney Disease (CKD)
Comparing Hemodiafiltration to Conventional Hemodialysis: Effects on Clinical and Biochemical Parameters
Chronic kidney disease may progress to end-stage renal disease, a stage in which the kidneys will no longer be able to adequately remove extra fluid and waste products from the body.
- Trial name
- NCT07662889
- Testing
- Conventional Hemodialysis, Hemodiafiltration
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Chronic Kidney Disease (CKD), CKD Stage 1-3
Multimedia Health Education on Physical Fitness and Physical Activity for Patients With Chronic Kidney Disease
This clinical trial aims to determine whether a multimedia educational intervention can effectively improve physical fitness and physical activity levels in patients with chronic kidney disease (CKD), while also evaluating its…
- Trial name
- NCT07493642
- Testing
- Multimedia Health Education, Standard Education Group
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Fu Jen Catholic University Hospital
ESRD, CKD (Chronic Kidney Disease) Stage 5D
Effect of Canagliflozin on Ultrafiltration & Fibrosis in Patients on Peritoneal Dialysis
This is a phase II, proof-of-concept, placebo-controlled, double-blind, cross-over randomized clinical trial, assessing the effect of canagliflozin on peritoneal membrane function in patients on PD.
- Trial name
- CAN-PD (NCT06913647)
- Testing
- Canagliflozin 300 MG
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Chronic Kidney Disease (CKD) Stage 5, Peritoneal Dialysis Access
PD Catheter Survival: Modified Percutaneous vs Moncrief-Popovich
Peritoneal dialysis (PD) catheter placement technique may affect catheter survival, functionality and infection risk. The Moncrief-Popovich (subcutaneous burying or embedding) technique was developed to reduce exit-site/tunnel…
- Trial name
- NCT07465445
- Testing
- Embedded Peritoneal catheter placement, Modified Percutaneous PD catheter placement
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital Civil de Guadalajara
Diabetes Mellitus Type 2 With Proteinuria, Diabetes Mellitus, Type 2
Treatment Optimization for Patients With Type 2 Diabetes Using Empagliflozin and Finerenone in a Remote Clinical Trial
The goal of this clinical trial is to determine the feasibility of remote clinical trial conduct in patients with type 2 diabetes and elevated albuminuria.
- Conditions
- Diabetes Mellitus Type 2 With Proteinuria, Diabetes Mellitus, Type 2, Diabetes Mellitus, Diabetes
- Trial name
- Optimize@Home (NCT06094920)
- Testing
- Empagliflozin 10 MG, Finerenone, Withings BPM Connect
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- University Medical Center Groningen
Kidney Transplantation, CKD (Chronic Kidney Disease) Stage 5D
Tubeless Spontaneous Ventilation Anesthesia in Kidney Transplantation
The aim of this clinical trial is to compare the intraoperative use of neuromuscular blocking agents and other anesthetic drugs between tubeless spontaneous ventilation anesthesia (TSVA) and conventional endotracheal intubation…
- Trial name
- NCT07377123
- Testing
- Tubeless Spontaneous Ventilation Anesthesia, Endotracheal Tube Anesthesia
- Volunteers
- 60 people
- Sponsor
- Jianxing He
Cardiac Surgery Associated - Acute Kidney Injury, CKD (Chronic Kidney Disease) Stage 5D
Incidence and Prognostic of Cardiac Surgery-Associated Acute Kidney Injury: A Spanish Multicenter Study (SCARS-AKI)
To predict the renal damage caused by cardiac surgery in patients to try to mitigate it as soon as possible
- Conditions
- Cardiac Surgery Associated - Acute Kidney Injury, CKD (Chronic Kidney Disease) Stage 5D, Acute Kidney Injury, Acute Kidney Disease
- Trial name
- SCARS-AKI (NCT07370831)
- Testing
- CARDIAC SURGERY
- Where
- Spain
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Universidad de Oviedo
Chronic Kidney Disease (CKD), Stages 3-4 Exercise Tolerance / Functional Capacity Vascular Health / Arterial Stiffness Fatigue in CKD
"Hypoxic vs. Aerobic Training in Chronic Kidney Disease
Chronic kidney disease (CKD) leads to poor exercise tolerance, vascular dysfunction, and reduced quality of life. This randomized controlled trial will compare intermittent hypoxic training (IHT) with traditional aerobic training…
- Trial name
- IHT-CKD (NCT07180875)
- Testing
- hypoventilation group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
CKD (Chronic Kidney Disease) Stage 5D, Uremia; Chronic
Studies on Adsorption International Learning Initiative Global
Use of sorption technologies in patients undergoing maintenance hemodialysis with inflammatory syndrome and clinical manifestations of uremia
- Conditions
- CKD (Chronic Kidney Disease) Stage 5D, Uremia; Chronic, Uremic; Toxemia, Inflammation Chronic
- Trial name
- SAILING (NCT07123909)
- Testing
- Patients will undergo a combined hemodialysis and hemosorption procedure. The study cartridge for hemosorption by Jafron HA130 contains the original adsorbing material.
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Botkin Hospital
ESRD (End Stage Renal Disease), Chronic Kidney Disease(CKD)
AP301 Efficacy and Safety in Chinese Dialysis Patients With Hyperphosphatemia
This Phase 3 clinical trial is the pivotal study of AP301 aiming to evaluate the efficacy and safety of AP301 for controlling serum phosphorus in chronic kidney disease receiving hemodialysis and peritoneal dialysis in Chinese…
- Conditions
- ESRD (End Stage Renal Disease), Chronic Kidney Disease(CKD), Hyperphosphatemia, Hyperphosphatemia in Chronic Kidney Disease
- Trial name
- RESPOND-1 (NCT07030595)
- Testing
- AP301, Sevelamer carbonate (Renvela®), AP301 Low Dose
- Where
- 50 sites in China
- Volunteers
- 474 people
- Sponsor
- Alebund Pharmaceuticals
Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Truway Diagnostic Tools in Primary Care
This study evaluates the effectiveness of Truway Health-sourced portable diagnostic devices, including ultrasound and blood glucose monitors, in early detection of chronic conditions in outpatient primary care settings.
- Conditions
- Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight, Hypertension, Cardiovascular Disease Acute
- Trial name
- TruDxPC (NCT07209527)
- Testing
- Truway Portable Ultrasound Device, Truway Blood Glucose Monitor, Standard Oral Hypoglycemic Agent
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Truway Health, Inc.
Osteopenia, Bone Metabolism Disorders
Effects of Aerobic Versus Resistance Training on Bone Metabolism in Stage 3-4 Chronic Kidney Disease
This randomized controlled trial investigates the comparative effects of aerobic versus resistance training on bone mineral density (BMD) and bone metabolism markers in patients with stage 3 or 4 chronic kidney disease (CKD).
- Conditions
- Osteopenia, Bone Metabolism Disorders, Chronic Kidney Disease (Stage 3-4), Mineral and Bone Disorder (CKD-MBD)
- Trial name
- CKD-BONE-EX (NCT07133256)
- Testing
- Resistance Exercise, Aerobic Training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sinai University
End Stage Renal Disease (ESRD), CKD 5D, Hemodialysis
Activated Charcoal Use in Chronic Kidney Disease Patients
Hyperphosphatemia management is initially based on restricting dietary phosphorus intake. Hyperphosphatemia is almost always seen in patients on dialysis and may contribute to progressive vascular calcification.
- Conditions
- End Stage Renal Disease (ESRD), CKD 5D, Hemodialysis, CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder
- Trial name
- NCT06906874
- Testing
- Activated Charcoal, Phosphate Binders
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
CKD (Chronic Kidney Disease) Stage 5D, Peritoneal Dialysis (PD)
The Effect of Exercise on Blood Pressure Variability on Peritoneal Dialysis Patients
In China, the chronic kidney disease (CKD) incidence rate is as high as 10.8%. Renal replacement therapy plays an critical role in the later stage of CKD and becomes mandatory, as end-stage renal disease (ESRD) is unavoidable in…
- Trial name
- NCT07098923
- Testing
- combination of aerobic and resistance exercise
- Where
- China
- Volunteers
- 55 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University