Clinical trials: Chronic Kidney Disease (CKD) Stage 5
Chronic Kidney Disease, Secondary Hyperparathyroidism
Comparison of I.V. CTAP201 and Doxercalciferol (Hectorol) in Subjects With Chronic Kidney Disease (CKD) and Secondary Hyperparathyroidism (SHPT)
This study will compare CTAP201 with Doxercalciferol in patients with chronic kidney disease (CKD) and secondary hyperparathyroidism (SHPT), undergoing regular hemodialysis, at different dose strengths.
- Conditions
- Chronic Kidney Disease, Secondary Hyperparathyroidism, Chronic Renal Insufficiency, Chronic Renal Failure
- Trial name
- NCT00792857
- Testing
- CTAP201 Injection, Doxercalciferol
- Where
- 6 sites in United States
- Volunteers
- 24 people
- Sponsor
- OPKO IP Holdings II, Inc.
Chronic Kidney Disease, Chronic Renal Failure
Exploring the Impact of " ACP Board Game for Life" on Death Preparation and Anxiety in Patients With Stage 4 and 5 Chronic Kidney Diseases: A Pilot Study
This study was to explore the impacts of participating in "ACP board game for life" on death preparation, death anxiety, end-of-life care preferences, and intervention perception in stage 4-5 CKD patients with advanced chronic…
- Conditions
- Chronic Kidney Disease, Chronic Renal Failure, Chronic Renal Insufficiency, End of Life Care
- Trial name
- NCT06046261
- Testing
- ACP board game for life
- Where
- Taiwan
- Volunteers
- 69 people
- Sponsor
- National Cheng-Kung University Hospital
Renal Insufficiency
Evaluation of the Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Chronic Kidney Disease Without Exposure to Gadolinium Based Contrast Agents (GBCA)
The objective of this long term study is to prospectively evaluate the incidence of NSF in patients with severe CKD or kidney failure including patients undergoing dialysis (stages 4 and 5 i.e., with an eGFR below 30)who have not…
- Trial name
- NCT00773409
- Where
- United States
- Volunteers
- 405 people
- Sponsor
- Bracco Diagnostics, Inc
Chronic Kidney Failure, Chronic Kidney Disease stage3
Pathophysiological Characterization of the Neuromuscular Function of a Population With Multiple Comorbidities Suffering From Chronic Renal Failure in Pre-dialysis.
The evolution of chronic kidney disease (CKD) causes a systemic upheaval on the body and a deep fatigue is very often described by patients (50-70% of the patients) even before the start of dialysis (pre-dialysis).
- Conditions
- Chronic Kidney Failure, Chronic Kidney Disease stage3, Chronic Kidney Disease, Stage 4 (Severe), Chronic Kidney Disease Stage 5
- Trial name
- PIONNIER (NCT03998917)
- Testing
- Discrimination of neuromuscular alterations protocol
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier le Mans
Stage 2-5 Chronic Kidney Disease, Predialysis
Vitamin D Insufficiency and Deficiency in Chronic Kidney Disease (CKD) Patients in Singapore
Vitamin D insufficiency and deficiency is common in chronic kidney disease (CKD) patients and is associated with elevated parathyroid hormone (PTH) concentration and mineral and bone disorder (MBD).
- Trial name
- NCT01102179
- Where
- Singapore
- Volunteers
- 196 people
- Sponsor
- National University of Singapore
Chronic Kidney Disease Stage 4, Chronic Kidney Disease Stage 3B
Fluorescein Angiography in Patients With Diabetes and Chronic Kidney Disease
Our study hypothesizes that fluorescein exposure in diabetic patients with advanced chronic kidney disease results in deterioration of kidney function.
- Conditions
- Chronic Kidney Disease Stage 4, Chronic Kidney Disease Stage 3B, Chronic Kidney Disease Stage 5, Diabetes Mellitus
- Trial name
- Fluo-AKI (NCT06760650)
- Testing
- Fluorescein angiography
- Where
- Lebanon
- Volunteers
- 35 people
- Sponsor
- Saint-Joseph University
Chronic Kidney Disease, Abdominal Muscles/Ultrasonography
Biomarkers, Abdominal Muscle, and Frailty in CKD
In chronic kidney disease (CKD), inflammation and oxidative stress are important processes that may be associated with the development of muscle loss and frailty.
- Conditions
- Chronic Kidney Disease, Abdominal Muscles/Ultrasonography, Frailty
- Trial name
- NCT07854275
- Testing
- total antioxidant status, total oxidant status, monocyte chemotactic protein-1
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Ankara City Hospital Bilkent
Anemia in Chronic Kidney Disease
An Exploratory Study to Evaluate FMX-8 to Treat Anemia in CKD
FMX-8 is a new type of drug being tested for the treatment of anemia in chronic illnesses.
- Trial name
- NCT02228655
- Testing
- FMX-8
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- FerruMax Pharmaceuticals, Inc.
Acute Renal Failure
AV Fistula Salvage in Advanced CKD Using Sodium Bicarbonate Prophylaxis
This is an observational study assessing the impact of conventional dose iodinated contrast on the renal function of advanced chronic kidney disease patients undergoing arteriovenous fistula evaluation using a standard sodium…
- Trial name
- NCT00621972
- Where
- United States
- Sponsor
- MaineHealth
Chronic Kidney Disease Stage 5 on Dialysis
Inspiratory Muscle Training for Chronic Kidney Disease Patients on Hemodialysis
Chronic Kidney Disease (CKD) is a global public health problem with an increasing prevalence and incidence, poor prognosis, and high costs.
- Trial name
- NCT05241652
- Testing
- Inspiratory Muscle Training with an intensity of 50% MIP, Inspiratory Muscle Training with an intensity of 10% MIP
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Padjadjaran
Renal Insufficiency, Chronic
Impact of Physical Activity on Patients With Chronic Kidney Disease Not Receiving Dialysis Followed in the TIRCEL Network. An Exposed / Unexposed Study (PHYSALYS)
PHYSALYS is an observational multicenter study. It's an analytical study comparing 2 groups: patients exposed to physical activity and unexposed.
- Trial name
- PHYSALYS (NCT02818010)
- Testing
- Global Physical Activity Questionnaire
- Volunteers
- 259 people
- Sponsor
- Hospices Civils de Lyon
Type 2 Diabetes Mellitus, Chronic Kidney Disease
Fasiglifam in Type 2 Diabetic Subjects With Chronic Kidney Disease Stage 4 or 5 on Hemodialysis
To evaluate the efficacy of fasiglifam 50 mg once daily compared to placebo on glycemic control as measured by glycosilated haemoglobin (HbA1c) over a 16-week treatment period in participants with Type 2 Diabetes Mellitus (T2DM)…
- Trial name
- NCT02015780
- Testing
- Fasiglifam, Antihyperglycemic therapy
- Where
- 30 sites in United States, Bulgaria and 5 more
- Sponsor
- Takeda
Chronic Kidney Disease (CKD)
Retrospective Analysis Assessing Clinical Risk Factors for Cardiovascular Events and Mortality and Development of a Risk Calculator in Chronic Kidney Disease Stage 5 on Dialysis
The purpose of this study is to evaluate which clinical and laboratory factors are associated with major adverse cardiovascular event (MACE) in chronic kidney disease (CKD) patients on dialysis.
- Trial name
- NCT04042350
- Testing
- Non-interventional
- Where
- Sweden
- Volunteers
- 2,773 people
- Sponsor
- Astellas Pharma Europe Ltd.
Hepatitis C, Chronic Kidney Diseases
Retrospective Efficacy and Safety Study With Elbasvir/Grazoprevir in HCV-infected Patients With Chronic Kidney Disease
Retrospective Efficacy and Safety Study With Elbasvir (EBR) 50 mg/Grazoprevir (GZR) 100 mg in Hepatitis C Virus (HCV)-infected Patients With Chronic Kidney Disease (CKD) Stage 4-5 During the French Temporary Authorization for Use…
- Trial name
- NCT03145623
- Testing
- Elbasvir and Grazoprevir
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Toulouse
End Stage Renal Disease, Chronic Kidney Disease Stage 5
Pharmacodynamic Study of AZD1722 in End-stage Renal Disease Patients on Hemodialysis
The purpose of this study is to determine if the study drug is safe, tolerable and active in reducing fluid overload/weight gain between dialysis sessions for patients with End Stage Renal Disease on Hemodialysis.
- Conditions
- End Stage Renal Disease, Chronic Kidney Disease Stage 5, ESRD
- Trial name
- NCT01764854
- Testing
- AZD1722 (in-patient), AZD1722 (out-patient)
- Where
- 3 sites in United States
- Volunteers
- 88 people
- Sponsor
- Ardelyx
CKD Stage 5
Potential Therapeutic Role of Effervescent Calcium-Magnesium Citrate in Chronic Kidney Disease Stage V
The Investigators plan to conduct a long-term trial to explore therapeutic implications of effervescent calcium magnesium citrate (EffCaMgCit) in CKD Stage V (end stage renal disease on hemodialysis).
- Trial name
- NCT03565913
- Testing
- EffCaMgCit, CaAcS
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- University of Texas Southwestern Medical Center
Anemia of Chronic Kidney Disease
A Pilot Study of KRX-0502 (Ferric Citrate, Administered Without Food, in Treating Iron-deficiency Anemia
The objective of the study is to evaluate the efficacy and safety of KRX-0502, administered without food, in treating iron deficiency anemia in subjects with stage 3 to 5 non-dialysis dependent chronic kidney disease (NDD-CKD).
- Trial name
- NCT02128074
- Testing
- KRX-0502
- Where
- 3 sites in Israel
- Volunteers
- 32 people
- Sponsor
- Keryx Biopharmaceuticals
Chronic Kidney Disease (Stages 4 and 5)
Kidney RISE: Randomized Integrated Supportive CarE Trial
The purpose of study is to investigate whether adding palliative care to usual chronic kidney disease (CKD) care improves symptoms and quality of life for people with CKD.
- Trial name
- NCT07741357
- Testing
- Kidney RISE
- Where
- 2 sites in United States
- Volunteers
- 280 people
- Sponsor
- NYU Langone Health
Kidney Diseases
Conversion From Standard Phosphate Binder Therapy to Fosrenol® (Lanthanum Carbonate) in Chronic Kidney Disease Stage 5
The main aim of this research study is to see if giving Fosrenol®, a chewable tablet, to patients on haemodialysis works as well as other treatments currently used to lower blood phosphorus levels.
- Trial name
- NCT00452478
- Testing
- Lanthanum carbonate
- Where
- 14 sites in Austria, Belgium and 4 more
- Volunteers
- 68 people
- Sponsor
- Shire
Chronic Kidney Disease - Stage V
Adipose Tissue & Uremia
Many metabolic disturbances, such as protein-energy wasting, inulin resistance, and dyslipidemia are common features of chronic kidney disease (CKD).
- Trial name
- MODAIR (NCT02902705)
- Testing
- Biopsy of abdominal subcutaneous white adipose tissue (2-3 g)
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Hospices Civils de Lyon