Clinical trials: Chronic Low Back Pain
Low Back Pain, Mechanical
Thoracic Lymphatic Pump Technique Exercises Chronic Mechanical Low Back Pain
The purpose of the study is to compare between the combined effect of thoracic lymphatic pump technique with exercises and exercises alone on pain intensity using Visual Analogue Scale (VAS), lumbar spine mobility using…
- Trial name
- NCT05568758
- Testing
- Thoracic lymphatic pump technique, Exercises (stretching and strenghtening )
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Chronic Low Back Pain, Sacroiliitis
Effectiveness of Ultrasound Guided Platelet Rich Plasma Injections in the Sacroiliac Joint
This prospective study will be quantitatively analyzing the effectiveness of platelet-rich-plasma (PRP) injections into the sacroiliac (SI) joint in relieving sacroiliitis and low back pain originating from the SI joint.
- Conditions
- Chronic Low Back Pain, Sacroiliitis, Sacroiliac; Backache, Platelet Rich Plasma
- Trial name
- NCT03122119
- Testing
- Platelet Rich Plasma Joint Injection
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Star Spine and Sport
Low Back Pain, Chronic Low Back Pain (CLBP)
Spinery Basivertebral Nerve Ablation for Vertebrogenic Chronic Low Back Pain
The goal of this clinical trial is to learn whether the Spinery® RF Generator and its sterile single-use accessories can safely lower disability and pain in adults with long-term low back pain that is thought to come from changes…
- Trial name
- BASILEA (NCT07696507)
- Testing
- Single Bipolar Ablation, Double Parallel Bipolar Ablation, Double Cross Bipolar Ablation
- Where
- 3 sites in Italy
- Volunteers
- 69 people
- Sponsor
- Axon srl
Low Back Pain
Influence of Kinesiophobia on the Outcome of Chronic Low Back Pain Condition
Though large body of evidence reported association between pain and kinesiophobia, there are paucity of studies in associating kinesiophobia to muscle endurance and position sense in patients with Chronic lower back pain [CLBP].
- Trial name
- NCT05079893
- Testing
- Case control study
- Volunteers
- 600 people
- Sponsor
- Gulf Medical University
Chronic Low-back Pain
ReActiv8 Stimulation Therapy vs Optimal Medical Management: A Randomized Evaluation
This study is a prospective, randomized study comparing ReActiv8 Therapy to Optimal Medical Management (OMM).
- Trial name
- RESTORE (NCT04803214)
- Testing
- ReActiv8
- Where
- 28 sites in United States
- Volunteers
- 203 people
- Sponsor
- Mainstay Medical
Subjects Suffering of Lateralized Lumbago on Side of the Malformation (Neo-articulation)
Involvement of Transverso-sacral- Neo- Articulations or of Transverso-iliac Articulations in Chronic Lumbago
The specific aim of this study is to determine whether, when treated with corticoid infiltration, certain chronic lumbagos could be explained by the presence of a neo-articulation.The primary criteria is to determine the…
- Trial name
- NCT01206699
- Testing
- corticoid (altim® 1.5 ml), physiological solution (1.5 ml)
- Where
- 2 sites in France
- Volunteers
- 16 people
- Sponsor
- Nantes University Hospital
Chronic Low-back Pain
Osteopathic Single CAse Research for Patients With Chronic Low Back Pain
This study aims to collect primary data from patients with low back pain to assess the effect of standard osteopathic management and biopsychosocially-informed osteopathic care using a Single-Case Experimental Design.
- Trial name
- OSCAR (NCT05120921)
- Testing
- Osteopathic Manual Treatment, Self-management, Reassurance
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- University College of Osteopathy
Back Pain Lower Back Chronic
Safety and Efficacy of Buprenorphine Transdermal System (BTDS) in Subjects With Moderate to Severe Low Back Pain
The objective of this study is to demonstrate the effectiveness and tolerability of the buprenorphine transdermal system (BTDS) 20 in comparison to the buprenorphine transdermal system (BTDS) 5 and oxycodone immediate-release in…
- Trial name
- NCT00313014
- Testing
- Buprenorphine, Oxycodone Immediate-Release
- Where
- 85 sites in United States
- Volunteers
- 660 people
- Sponsor
- Purdue Pharma LP
Pain, Pain, Chronic
Long Term Use of a High Energy Pulsed Heating Device in the Management of Chronic Pain
The purpose of this study is to evaluate the Soovu Labs pain Relief System in a group of users that represent people most likely to purchase and use the units. This study is called an In Home Users Trial (IHUT).
- Conditions
- Pain, Pain, Chronic, Pain, Back
- Trial name
- NCT04407884
- Testing
- Soovu Labs Inc. Pain Relief System
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Soovu Labs Inc.
Low Back Pain, Core Muscles
Gamified Home-Based Core Neuromuscular Training for Chronic Low Back Pain
This randomized controlled trial aims to evaluate the effects of gamified home-based core neuromuscular training on pain intensity, functional disability, core muscular endurance, and exercise adherence in women with chronic…
- Trial name
- NCT07890363
- Testing
- Gamified Intervention Group: core neuromuscular exercise program using a digital application with gamification features, Non-Gamified Control Group
- Volunteers
- 60 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
Chronic Pain, Low Back Pain
Increased Emotional-motivational Processing in Patients with Chronic Pain and Its Neural Correlates
Chronic pain causes immense suffering and reductions in quality of life as well as enormous socioeconomic costs. Very many chronic pain patients fall into the category of unspecific pain, i.e.
- Trial name
- NCT05257356
- Testing
- psychophysical tasks
- Where
- Switzerland
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- susanne becker
Low Back Pain, Chronic Pain
Efficacy and Safety Study of NKTR-181 in Opioid-Naive Subjects With Low Back Pain
The purpose of this study is to determine whether a new opioid molecule, NKTR-181, is effective for the relief of moderate to severe chronic low back pain as compared to a placebo.
- Trial name
- SUMMIT-07 (NCT02362672)
- Testing
- NKTR-181 BID tablets
- Where
- 54 sites in United States
- Volunteers
- 1,189 people
- Sponsor
- Nektar Therapeutics
Myofascial Pain Syndrome
Massage of the Low Back Muscles Assessed With Ultrasound Scanning
The aim of the study is to use diagnostic ultrasound to compare the thickness of soft tissues in the low back in a group of patients with chronic low back pain treated with massage to a control group of non-treated patients.
- Trial name
- NCT01174667
- Testing
- Specific massage for fascial release, Quiet non-instructed rest for 3 minutes
- Volunteers
- 70 people
- Sponsor
- Anglo-European College of Chiropractic
Chronic Low-back Pain
The Lumbar Interbody Fusion vs. Multidisciplinary Rehabilitation (LIFEHAB) Trial
The goal of this randomized controlled trial is to compare lumbar interbody fusion surgery with multidisciplinary rehabilitation in participants aged 20-65 years with persisting (≥ one year) low back pain.
- Trial name
- LIFEHAB (NCT06169488)
- Testing
- Lumbar Interbody Fusion, Multidisciplinary rehabilitation
- Where
- 5 sites in Norway
- Volunteers
- 202 people
- Sponsor
- Oslo University Hospital
Chronic Low-back Pain
Digital Care Program for Chronic Low Back Pain
New ways of delivering care are much needed to address chronic low back pain. Crucially, these need to: a) address the three pillars of care to achieve good and sustained clinical outcomes; b) overcome barriers to access; c)…
- Trial name
- NCT04808141
- Testing
- Digital program, Conventional physical therapy
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Sword Health, SA
Low Back Pain
Belt Squat Training for Non-Specific Low Back Pain
The purpose of this project is to investigate the feasibility of using belt squat as an exercise intervention for people with chronic low back pain.
- Trial name
- NCT06594731
- Testing
- Hip belt squat training
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mathias Kristiansen
Low Back Pain
The McKenzie Method Versus Manipulation for Patients With Chronic Low Back Pain
Introduction: The McKenzie method as well as spinal manipulation is commonly used for the treatment of low back pain throughout the western world.
- Trial name
- NCT00939107
- Testing
- spinal manipulation, McKenzie exercises
- Where
- Denmark
- Volunteers
- 350 people
- Sponsor
- Back and Rehabilitation Center, Copenhagen
Low Back Pain
The Effect of Traditional Mat Exercises Versus Reformer Pilates and Hammock Yoga on Chronic Back Pain
The purpose of the present study was to examine the effects of traditional mat exercises, Reformer Pilates and Hammock Yoga approaches on pain, endurance, balance, disability, and quality of life of individuals who had Chronic…
- Trial name
- NCT05992766
- Testing
- Reformer Pilates, Hammock Yoga, Traditional mat exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hasan Kalyoncu University
Gluteus Maximus, Low Back Pain
Effect of Gluteus Maximus Strengthening on Back Pain, Range Of Motion and Endurance in Desk-Job Workers With Chronic Low Back Pain
The goal of this clinical trial is to learn Effect of strengthening of Gluteus maximum on 40 Desk- Job workers with low back pain and Range of motion he main questions it aims to answer are: 1.
- Conditions
- Gluteus Maximus, Low Back Pain, Exercise Training, Range of Motion
- Trial name
- NCT07598812
- Testing
- Electrotherapy ( TENS or IF) , postural education , active range of motion for lumbar spine, strengthening exercises
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Chronic Low Back Pain
Yoga for Chronic Low Back Pain and Its Mechanism of Action: Impact of Strength and Stretch (YoMA II)
This study is a pilot, randomized controlled trial to provide feasibility and conduct preliminary analyses on physical (strength and stretch) mechanisms associated with a yoga intervention for non-specific chronic low back pain…
- Trial name
- NCT02552992
- Testing
- Yoga, Self-Directed Mind-Body Program
- Volunteers
- 22 people
- Sponsor
- University of California, San Francisco