Clinical trials: Chronic Low Back Pain (cLBP)
Low Back Pain, Recurrent, Neuropathic Pain
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting
The investigators will select two study groups from a population of patients with severe chronic low back pain (CLBP) of facet joint (FJ) origin already treated with conventional radiofrequency ablation (CRFA) of the medial…
- Conditions
- Low Back Pain, Recurrent, Neuropathic Pain, Facet Joint Pain, Central Sensitisation
- Trial name
- NCT04542798
- Testing
- Radiofrequency COSMAN
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital General Universitario de Valencia
Chronic Low Back Pain (CLBP)
Lumber Stabilization Exercise Versus Back Endurance Exercise Among Female University Students
Low Back Pain (LBP) as estimates show that up to 84% of adults will experience LBP at some point in their lifetime, ranking it as a leading cause of disability globally.
- Trial name
- NCT07163117
- Testing
- lumbar stabilization exercises, endurance training, Home based program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Chronic Low Back Pain
Yoga for Veterans With CLBP
Chronic low back pain (CLBP) is a prevalent condition among VA patients, but many current treatment options have limited effectiveness.
- Trial name
- NCT02524158
- Testing
- Yoga Therapy for CLBP
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- VA Office of Research and Development
Chronic Low Back Pain
Case Series Evaluation of Psychodynamic Interpersonal Therapy in Chronic Low Back Pain
Many people in the world have chronic pain; this is pain which lasts more than twelve weeks. Pain can cause people to feel low in mood and change how they feel about themselves and others around them.
- Trial name
- NCT03658226
- Testing
- Psychodynamic Interpersonal Therapy (PIT)
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Charlotte Morgan
Chronic Low Back Pain (CLBP), Heart Rate Variability
Autonomic Differences in Heart Rate Variability Between Healthy and Chronic Low Back Pain Subjects
This study aims to evaluate the autonomic differences in heart rate variability (HRV) between healthy individuals and those with chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Heart Rate Variability, Autonomic Nervous System Dysfunction
- Trial name
- NCT06760390
- Where
- Spain
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Chronic Low Back Pain (CLBP), Sacroiliac Joint Dysfunction
Connective Tissue Dry Needling for Low Back Pain Related to Local Posterior Superior Iliac Spine Pain
This single-blind randomized controlled trial will aim to determine the effectiveness of a connective tissue dry needling (CTDN) technique, in reducing pain and improving function in individuals with chronic mechanical low back…
- Conditions
- Chronic Low Back Pain (CLBP), Sacroiliac Joint Dysfunction, Mechanical Low Back Pain
- Trial name
- NCT07345871
- Testing
- Connective tissue dry needling, Exercise therapy
- Volunteers
- 42 people
- Sponsor
- University of Social Welfare and Rehabilitation Science
Chronic Low-back Pain (cLBP)
Effects of a Hip Flexor and Extensor Muscle Training Program in Individuals with Chronic Mechanical Low Back Pain
The goal of this clinical trial is to evaluate the effect of a physiotherapy intervention program in the lumbopelvic area in chronic low back pain patients. The main questions it aims to answer are: 1.
- Trial name
- NCT06787209
- Testing
- Program to improve lumbopelvic function., generic health care
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Lucía Pilar Vicente Pina
Chronic Low-back Pain (cLBP)
Effects of a Land and Aquatic Exercise-based Program on Pain, Mobility and Quality of Life in Patients With Chronic Low Back Pain
The goal of this randomized clinical trial] is to study the effect of a combined aquatic and land-based exercise program compared to an aquatic program on pain, functional disability, and quality of life in adults with chronic…
- Trial name
- NCT06641570
- Testing
- Aquatic Exercise Program, Land-based Exercise Program
- Where
- Portugal
- Volunteers
- 41 people
- Sponsor
- Instituto Politécnico de Leiria
Chronic Low-back Pain (cLBP), Urinary Incontinence (UI)
Effects of PEMM in Chronic Low Back Pain Women With Urinary Incontinence
Urinary incontinence (UI), Chronic low back pain (CLBP) in women are prevalent and often coexist. Multiple conditions when coexist, it leads to reduced Quality of life in turn causing physical and mental impairment.
- Conditions
- Chronic Low-back Pain (cLBP), Urinary Incontinence (UI), Pelvic External Myofascial Mobilisation, Myofascial Techniques
- Trial name
- NCT07351851
- Testing
- PEMM with Theragun, Active Comparator: Control
- Where
- Qatar
- Volunteers
- 200 people
- Sponsor
- Hamad Medical Corporation
Chronic Low Back Pain
Effects of OMT on Interoception
Recent evidence suggested that the anterior insula cortex seems to be the main site of interoception. Several studies showed an association between change in insula function and interoception, bodily perception and consciousness…
- Trial name
- NCT02464475
- Testing
- osteopathic manipulative treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Come Collaboration
Pain Threshold, Low Back Pain
Relationship Between Pressure Pain Threshold and Pain Intensity, Affect and Disability in CLBP
The association between pressure pain threshold and different aspects of low back pain has garnered attention over the years. However, since most of such studies in the past employed cross sectional designs, a longitudinal study…
- Conditions
- Pain Threshold, Low Back Pain, Pain Measurement
- Trial name
- NCT04482075
- Testing
- segmental stability training
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- Dow University of Health Sciences
Chronic Low Back Pain (CLBP)
Impairment Based Treatment Versus Modified Functional Restoration Program in Chronic Low Back Pain Patients
The aim of this feasibility study is to evaluate the practicality of conducting a future randomized controlled trial comparing two rehabilitation approaches for older adults with degenerative chronic low back pain…
- Trial name
- FIRM-CLBP (NCT07699419)
- Testing
- Impairment-based trearment, Modified Functional restoration program
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Low-back Pain (cLBP)
Clinical Research of Effectiveness and Safety of Herbal Medicine Strategy for Chronic Low Back Pain
This study is a pragmatic multicenter randomized controlled trial evaluating the effectiveness and safety of herbal medicine strategy for chronic low back pain, using standard Korean medicine treatment as the control.
- Trial name
- NCT07058376
- Testing
- Herbal Medicine Strategy, Standard Korean Medicine Treatment
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Jaseng Medical Foundation
Chronic Low Back Pain (CLBP)
Neuroimmune Responses to Exercise in Chronic Back Pain
The goal of this mechanistic clinical trial is to learn how physical exercise affects the body and brain in people with chronic low back pain.
- Trial name
- eCLBP (NCT07497425)
- Testing
- Physical Exercise
- Where
- Canada
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- McGill University
Chronic Lower Back Pain (CLBP), Lumbar Facet Joint Pain
Lumbar Facet Platelet-Rich Plasma Injection Versus Medial Branch Radiofrequency Ablation for Chronic Lumbar Facet-Mediated Pain
The first clinical research effort under this initiative is a pilot randomized controlled trial comparing intra-periarticular lumbar facet platelet-rich plasma (PRP) injection to standard-of-care medial branch radiofrequency…
- Trial name
- NCT07692737
- Testing
- Platelet Rich Plasma Joint Injection, Medial branch radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- The New England Baptist Hospital
Chronic Low-back Pain (cLBP)
Yoga and Mindfulness for Chronic Low Back Pain: A Randomized Controlled Trial
Chronic low back pain (CLBP) is a leading cause of disability, significantly impacting quality of life and work productivity. Traditional treatments often provide limited relief, necessitating alternative approaches.
- Trial name
- NCT06910982
- Testing
- Sphinx Pose Yoga Therapy
- Where
- Pakistan
- Volunteers
- 220 people
- Sponsor
- University of Karachi
Low Back Pain, Chronic Low-back Pain (cLBP)
Virtual Tai Chi for Chronic Low Back Pain (Spine 2027)
This study tests whether a virtually delivered integrated tai chi, qigong, and meditation program, added to usual care, improves chronic low back pain, disability, quality of life, and healthcare costs compared with usual care…
- Trial name
- NCT07772154
- Testing
- Virtually Delivered Integrated Tai Chi, Qigong, and Meditation (VDTQM)
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- New York Medical College
Chronic Non-specific Low Back Pain
Prolotherapy in Acupoints in Chronic Non-specific Low Back Pain (cLBP)
Chronic non-specific low back pain (CNSLBP) is among the most prevalent causes of disability on the planet, which often proves to be refractory to conventional pharmacological, interventional, and rehabilitation approaches.
- Trial name
- NCT07296653
- Testing
- Dextrose 15% and lidocaine 1% infiltration, Lidocaine 1% infiltration
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- National and Kapodistrian University of Athens
Virtual Reality, Kinesiophobia
Can Virtual Reality Exercise Help Restore Both Body and Mind in Chronic Low Back Pain
The goal of this clinical trial is to learn if an immersive virtual reality (VR) exercise program can help reduce back pain and improve physical function and psychological well-being in adults with chronic low back pain.
- Conditions
- Virtual Reality, Kinesiophobia, Chronic Low Back Pain (CLBP), Central Sensitization
- Trial name
- NCT07207083
- Testing
- Immersive Virtual Reality-based Exercise (FitXR, Meta Quest 3s), Conventional Exercise Program (Matched Exercise, without VR)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- dongmin kang
Low Back Pain, Paraspinal Muscle
Sodium Aescinate for the Treatment of Low Back Pain (LBP) in Adults
The goal of this clinical trial is to assess the clinical efficacy and safety of sodium aescinate in treating low back pain (LBP) in adult participants.
- Conditions
- Low Back Pain, Paraspinal Muscle, CLBP - Chronic Low Back Pain, Non-specific Chronic Low Back Pain
- Trial name
- NCT07339631
- Testing
- Sodium Aescinate Tablets
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xijing Hospital