Clinical trials: Chronic Low-back Pain (cLBP)
Fibromyalgia, Lupus Erythematosus, Systemic
Brief Pain Exposure Therapy (BPET) For Nociplastic Pain
This study is intended to test whether a brief Zoom-based behavioral treatment can help adults with fibromyalgia (FM), Lupus, chronic pelvic pain, and chronic low back pain learn effective strategies for reducing pain, disability…
- Conditions
- Fibromyalgia, Lupus Erythematosus, Systemic, Chronic Pelvic Pain, Chronic Low Back Pain (CLBP)
- Trial name
- BPET (NCT06208514)
- Testing
- Brief pain exposure therapy (BPET)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Michigan
Chronic Low Back Pain (CLBP)
Clinical Investigation to Assess the Clinical Effect of the LumbaCure® Intervention on Patients Suffering From Chronic Low Back Pain
Low Back Pain (LBP) is one of the common causes of morbidity worldwide, with a one-month prevalence of 23.3 %. Number of people with LBP reached 577 million people in 2020.
- Trial name
- LumbaCure2302 (NCT06662032)
- Testing
- LumbaCure®, Rehab program
- Where
- 2 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Odix
Fibromyalgia (FM), Chronic Low Back Pain (CLBP)
Pain Neuroscience Education for Chronic Pain
Chronic pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, with a high prevalence in Spain (25.9%) and an average duration of 6.83 years, highlighting its significant health…
- Conditions
- Fibromyalgia (FM), Chronic Low Back Pain (CLBP), Chronic Pain
- Trial name
- PNE (NCT07693998)
- Testing
- Therapeutic Exercise and Education in Pain Neuroscience
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- University of Valencia
Chronic Low Back Pain (CLBP)
A Mediation Analysis Investigating Dry Needling Treatment Mechanisms in a Chronic Low Back Pain Population
Low back pain is a common problem that many adults experience at some point in their lives. One treatment being studied is dry needling, a technique where a small needle is inserted into a specific area of muscle to help relieve…
- Trial name
- NCT06940492
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Florida
Chronic Low-back Pain (cLBP)
Biopsychosocial Model-based Care Versus Routine Physical Therapy in Chronic Back Pain
Chronic low back pain (CLBP) is a multifactorial condition influenced by physical, psychological, and social factors. Conventional physical therapy primarily targets biomechanical impairments, often neglecting psychosocial…
- Trial name
- NCT07280806
- Testing
- Biopsychosocial model based care, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Nonspecific Chronic Low Back Pain
Psychometric Validation of Persian CBQ-NSCLBP
This study aims to translate, culturally adapt, and psychometrically validate the Persian version of the Cognitive Behavioral Questionnaire in Nonspecific Chronic Low Back Pain (CBQ-NSCLBP).
- Trial name
- NCT07033377
- Testing
- Self-administered paper-based questionnaires
- Volunteers
- 120 people
- Sponsor
- Kourosh Najafi
Cancer Survivorship, Chronic Low Back Pain (CLBP)
Exploring Physiotherapist's Knowledge, Attitudes, Beliefs and Clinical Decision-making Regarding Physical Activity in Chronic Pain Management.
Chronic pain is a globally increasing problem, with enormous impact on the individual and society. Within the treatment of chronic pain, physical activity is a key strategy to improve pain-related complaints.
- Conditions
- Cancer Survivorship, Chronic Low Back Pain (CLBP), Physiotherapy and Rehabilitation
- Trial name
- PPS (NCT06605729)
- Testing
- e-learning
- Where
- Belgium
- Volunteers
- 330 people
- Sponsor
- Universiteit Antwerpen
Chronic Low-back Pain (cLBP)
Combining Brain Stimulation and Physiotherapy for the Management of Chronic Low Back Pain
Chronic low back pain (CLBP) is a major health challenge in Canada, leading to substantial disability and socioeconomic burden, particularly among Veterans. In military Veterans, LBP is the most common chronic pain condition.
- Trial name
- NCT06999772
- Testing
- Active rTMS, Psychologically-informed physiotherapy (PiP), Usual physiotherapy
- Where
- 2 sites in Canada
- Volunteers
- 96 people
- Sponsor
- Laval University
Chronic Low Back Pain (CLBP)
Study of Correlation Between Serum BDNF Levels and Pfirmann Grading and IL- 1β
Brain-derived neurotrophic factor (BDNF) is a protein belonging to the neurotrophin family, known to be involved in neuronal survival, growth, and synaptic plasticity.
- Trial name
- NCT07807839
- Testing
- blood sampling for ELISA
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Keimyung University Dongsan Medical Center
Non-Specific Chronic Lower Back Pain
Randomized Blinded Evaluation of the Effects of TENS and IFC Compared to a Sham Device and SOC in Patients With Non-Specific CLBP
This is a prospective, sham-controlled, randomized, single-blinded, multi-center study comparing two different modes of the NexWave device, transcutaneous electrical nerve stimulation (TENS) and interferential current (IFC), with…
- Trial name
- NCT05972889
- Testing
- NexWave
- Where
- 8 sites in United States
- Volunteers
- 334 people
- Sponsor
- Zynex Medical, Inc.
Chronic Low-back Pain (cLBP)
Effects Of Vacuum Controlled Static Versus Vacuum Controlled Dynamic Dry Cupping On Pain, Range Of Motion And Disability Among Patients With Chronic Low Back Pain
This randomized controlled clinical trial aims to compare the effects of vacuum-controlled static dry cupping and vacuum-controlled dynamic dry cupping on pain intensity, lumbar range of motion, and functional disability in…
- Trial name
- NCT07702617
- Testing
- Vacuum-Controlled Static Dry Cupping, Vacuum-Controlled Dynamic Dry Cupping
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Mechanical Low Back Pain, Chronic Low Back Pain (CLBP)
Iliopsoas Counterstrain and Mechanical Chronic Low Back Pain
The aim of this study is to determine the effects of the Strain-Counterstrain (SCS) technique on alleviating sudden and mechanical chronic low back pain and resolving limited lumbar flexion and extension in individuals with…
- Trial name
- NCT06748859
- Testing
- Counterstrain technique, Exercise therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Marmara University
Chronic Low-back Pain (cLBP)
Therapeutic Exercise Plus Pain Neuroscience Education for Chronic Low Back Pain
### What is this study about? This study looked at whether adding pain neuroscience education (PNE) to standard therapeutic exercise helps people with chronic low back pain who are afraid of moving (a condition called…
- Trial name
- NCT07856992
- Testing
- Therapeutic exercise, Pain Neuroscience Education
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Qingdao Municipal Hospital
Chronic Low Back Pain (CLBP)
Virtual Reality Programme Incorporating Psychology and Physiotherapy for Chronic Low Back Pain
The main objective of this randomized controlled pilot trial is to investigate the efficacy of a 4-week multidisciplinary intervention for patients with chronic non-specific low back pain, combining a therapeutic exercise program…
- Trial name
- CLEVER-BODY (NCT06757413)
- Testing
- Enhanced Virtual reality, Active Comparator: Treatment as usual
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- Cardenal Herrera University
CLBP - Chronic Low Back Pain
Effect Virtual Reality Fully Immersive Based Exercise Game on Reducing Fear of Movement in People With CLBP
Low back pain is one of the most common problems among adults and a leading cause of disability worldwide including in Saudi Arabia (Buchbinder et al., 2018) (Awaji, 2016) .
- Trial name
- NCT05267756
- Testing
- (kurki-application),VR glasses
- Where
- Saudi Arabia
- Volunteers
- 28 people
- Sponsor
- King Saud University
Low Back Pain, Back Pain Lower Back Chronic
Brain Imaging Study of Acupuncture in Chronic Low Back Pain
We are doing this research study to learn about how acupuncture treatment works. This study is being done to look at changes in the brain, NOT to treat pain. We want to learn about brain activity during acupuncture.
- Conditions
- Low Back Pain, Back Pain Lower Back Chronic, Low Back Pain, Recurrent
- Trial name
- NCT01614639
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Chronic Low Back Pain
Case Series Evaluation of Psychodynamic Interpersonal Therapy in Chronic Low Back Pain
Many people in the world have chronic pain; this is pain which lasts more than twelve weeks. Pain can cause people to feel low in mood and change how they feel about themselves and others around them.
- Trial name
- NCT03658226
- Testing
- Psychodynamic Interpersonal Therapy (PIT)
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Charlotte Morgan
Virtual Reality, Kinesiophobia
Can Virtual Reality Exercise Help Restore Both Body and Mind in Chronic Low Back Pain
The goal of this clinical trial is to learn if an immersive virtual reality (VR) exercise program can help reduce back pain and improve physical function and psychological well-being in adults with chronic low back pain.
- Conditions
- Virtual Reality, Kinesiophobia, Chronic Low Back Pain (CLBP), Central Sensitization
- Trial name
- NCT07207083
- Testing
- Immersive Virtual Reality-based Exercise (FitXR, Meta Quest 3s), Conventional Exercise Program (Matched Exercise, without VR)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- dongmin kang
Chronic Non-specific Low Back Pain
Prolotherapy in Acupoints in Chronic Non-specific Low Back Pain (cLBP)
Chronic non-specific low back pain (CNSLBP) is among the most prevalent causes of disability on the planet, which often proves to be refractory to conventional pharmacological, interventional, and rehabilitation approaches.
- Trial name
- NCT07296653
- Testing
- Dextrose 15% and lidocaine 1% infiltration, Lidocaine 1% infiltration
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- National and Kapodistrian University of Athens
Chronic Low Back Pain (CLBP), Low Back Pain
Chronic Low Back Pain and Osteopathic Manipulation Treatment
The goal of this clinical trial is to learn if adding Osteopathic Manipulative Therapy (OMT) to the usual medical care provided at the VA (usual VA care) improves treatment outcomes in individuals with chronic low back pain…
- Trial name
- NCT07161661
- Testing
- Usual VA Care, Osteopathic manipulative treatment
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Edward Hines Jr. VA Hospital