Clinical trials: Chronic Low-back Pain (cLBP)
Chronic Low Back Pain (CLBP), Heart Rate Variability
Autonomic Differences in Heart Rate Variability Between Healthy and Chronic Low Back Pain Subjects
This study aims to evaluate the autonomic differences in heart rate variability (HRV) between healthy individuals and those with chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Heart Rate Variability, Autonomic Nervous System Dysfunction
- Trial name
- NCT06760390
- Where
- Spain
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Low Back Pain, Chronic Low Back Pain (CLBP)
Spinery Basivertebral Nerve Ablation for Vertebrogenic Chronic Low Back Pain
The goal of this clinical trial is to learn whether the Spinery® RF Generator and its sterile single-use accessories can safely lower disability and pain in adults with long-term low back pain that is thought to come from changes…
- Trial name
- BASILEA (NCT07696507)
- Testing
- Single Bipolar Ablation, Double Parallel Bipolar Ablation, Double Cross Bipolar Ablation
- Where
- 3 sites in Italy
- Volunteers
- 69 people
- Sponsor
- Axon srl
Chronic Low-back Pain (cLBP)
Virtual Reality Based High-intensity Interval Training in Chronic Low Back Pain
One of the most prevalent causes of pain on a global scale is chronic musculoskeletal pain. Low back pain is a prevalent manifestation of chronic musculoskeletal pain.
- Trial name
- NCT07388134
- Testing
- Virtual reality based high intensity interval training (VR-HIIT) group, High intensity interval training (HIIT) group
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Universidad de Granada
Chronic Low Back Pain (CLBP), Acute Low Back Pain
Multimodal Imaging and Biospecimen Collection for Low Back Pain (LBPB)
This prospective cohort study investigates the neurobiological, genetic, and psychosocial mechanisms underlying acute and chronic low back pain (LBP).
- Conditions
- Chronic Low Back Pain (CLBP), Acute Low Back Pain, Low Back Pain, Chronic Pain
- Trial name
- LBPB (NCT06967363)
- Testing
- Nerve Block, endoscopic spinal disecetomy, Medication
- Where
- 2 sites in China
- Volunteers
- 360 people
- Sponsor
- Peking University Third Hospital
Chronic Low-back Pain (cLBP), Urinary Incontinence (UI)
Effects of PEMM in Chronic Low Back Pain Women With Urinary Incontinence
Urinary incontinence (UI), Chronic low back pain (CLBP) in women are prevalent and often coexist. Multiple conditions when coexist, it leads to reduced Quality of life in turn causing physical and mental impairment.
- Conditions
- Chronic Low-back Pain (cLBP), Urinary Incontinence (UI), Pelvic External Myofascial Mobilisation, Myofascial Techniques
- Trial name
- NCT07351851
- Testing
- PEMM with Theragun, Active Comparator: Control
- Where
- Qatar
- Volunteers
- 200 people
- Sponsor
- Hamad Medical Corporation
Chronic Low-back Pain (cLBP)
Yoga and Mindfulness for Chronic Low Back Pain: A Randomized Controlled Trial
Chronic low back pain (CLBP) is a leading cause of disability, significantly impacting quality of life and work productivity. Traditional treatments often provide limited relief, necessitating alternative approaches.
- Trial name
- NCT06910982
- Testing
- Sphinx Pose Yoga Therapy
- Where
- Pakistan
- Volunteers
- 220 people
- Sponsor
- University of Karachi
Chronic Low-back Pain (cLBP), Chronic Low-back Pain
Effectiveness of a Multidisciplinary Treatment for Patients With Chronic Low Back Pain
PAINDOC is a treatment program that includes 4 disciplines that, separately, have demonstrated their effectiveness in the treatment of chronic low back pain: education in pain neuroscience, therapeutic education (Empowered…
- Conditions
- Chronic Low-back Pain (cLBP), Chronic Low-back Pain, Back Pain
- Trial name
- PAINDOC (NCT06679205)
- Testing
- Multidisciplinary and multimodal intervention, Usual Care
- Where
- 2 sites in Spain
- Volunteers
- 62 people
- Sponsor
- University of Barcelona
Chronic Low Back Pain (CLBP), Aging
Trunk Control Training and Walking in Older Adults
The goal of this observational study and clinical trial is to evaluate control of trunk posture and walking biomechanics in 20 older adults with chronic low back pain and 20 older adult healthy volunteers.
- Trial name
- NCT06782919
- Testing
- Trunk control training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Low Back Pain, Kinesiophobia (Fear of Movement)
Impact of the Receptive Music Intervention Tool (MUSIC CARE©) on Changes in the Functional Abilities of Patients With Chronic Low Back Pain
Brief Summary The goal of this clinical trial is to learn if MUSIC CARE©, a music-based therapy tool, can improve the physical abilities of people with chronic low back pain (back pain that lasts more than 3 months).
- Conditions
- Low Back Pain, Kinesiophobia (Fear of Movement), Chronic Low-back Pain (cLBP)
- Trial name
- LOMBALZIC' (NCT07731204)
- Testing
- Receptive Music Therapy
- Where
- France
- Volunteers
- 34 people
- Sponsor
- LNA SANTE
Chronic Low-back Pain (cLBP), Myofacial Pain
Treatment Validation for Myofascial Pain
The goal of this clinical trial is to see if a body test called the NUN biomarker can track changes in chronic low back pain after dry needling and predict who will feel better.
- Trial name
- NCT07133139
- Testing
- Dry Needling, NUN Biomarker
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Ajay Wasan, MD, Msc
Chronic Lower Back Pain (CLBP), Lumbar Facet Joint Pain
Lumbar Facet Platelet-Rich Plasma Injection Versus Medial Branch Radiofrequency Ablation for Chronic Lumbar Facet-Mediated Pain
The first clinical research effort under this initiative is a pilot randomized controlled trial comparing intra-periarticular lumbar facet platelet-rich plasma (PRP) injection to standard-of-care medial branch radiofrequency…
- Trial name
- NCT07692737
- Testing
- Platelet Rich Plasma Joint Injection, Medial branch radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- The New England Baptist Hospital
Non-specific Chronic Low Back Pain, Chronic Low-back Pain (cLBP)
Mindfulness-Based Therapy for Chronic Low Back Pain in Office Workers
This study evaluated whether a mindfulness-based therapy program could reduce pain severity in office workers with non-specific chronic low back pain.
- Conditions
- Non-specific Chronic Low Back Pain, Chronic Low-back Pain (cLBP), Mindfulness Meditation
- Trial name
- NCT07621302
- Testing
- Mindfulness-Based Therapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Dokuz Eylul University
Chronic Low Back Pain (CLBP)
Disc Puncture Does Not Accelerate Degenerative Changes in Lumbar Discs of Patients With Discogenic Pain
Procedures 10 years ago performed included intradiscal nucleoplasty (ACUTHERM) and intradiscal electrothermal therapy (IDET). At follow up MRI scans evaluated by two blinded specialists for disc degeneration were carried out.
- Trial name
- NCT07567404
- Testing
- Intradiscal electrothermal Therapy
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- SRH Gesundheitszentrum Bad Herrenalb
Chronic Low Back Pain (CLBP), Lumbar Spondylosis
Efficacy of Electroacupuncture Combined With Auricular Acupressure for Chronic Low Back Pain.
Chronic low back pain (CLBP) due to lumbar spondylosis is a leading cause of disability, significantly impacting the quality of life in middle-aged and elderly populations.
- Trial name
- NCT07530042
- Testing
- Electroacupuncture, Auricular Acupressure
- Where
- Vietnam
- Volunteers
- 76 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Chronic Low Back Pain
Management of Chronic Low Back Pain in Older Adults Using Auricular Point Acupressure
Almost one-third (30%) of persons 60 years and older suffer from cLBP and cause a significant negative impact on individuals and society in the U.S.
- Trial name
- NCT03589703
- Testing
- Target ear points related to chronic low back pain (T-APA), Non-Target ear Points not related to chronic low back pain (NT-APA), Enhanced Educational Control Group (CG-2)
- Where
- 2 sites in United States
- Volunteers
- 272 people
- Sponsor
- The University of Texas Health Science Center, Houston
Chronic Low-back Pain (cLBP)
Combined and Aquatic Exercise in Chronic Low Back Pain
The goal of this randomized clinical trial is to evaluate the effects of a combined aquatic- and land-based exercise program, as well as an aquatic-exercise program, compared with a control group receiving home-based exercise, on…
- Trial name
- NCT07732595
- Testing
- Aquatic-exercise Program, Land-based Exercise Program, Home-based Exercise Program
- Where
- Portugal
- Volunteers
- 90 people
- Sponsor
- University of Beira Interior
Chronic Low Back Pain (CLBP), Nociplastic Pain
PRT for Chronic Low Back Pain
The goal of this clinical trial is to learn whether Pain Reprocessing Therapy (PRT) is a feasible and acceptable treatment to complete for working-age adults (ages 18-65) with chronic low back pain.
- Trial name
- NCT07696741
- Testing
- Pain Reprocessing Therapy, Monitoring and Education
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Chronic Low Back Pain (CLBP)
Comparative Study on SNAG From Different Positions Low Back Pain Treatment
Objectives: To compare the effects of lumbar sustained natural apophyseal glides (SNAGs) applied in loaded versus unloaded positions on pain, disability, and function in individuals with chronic nonspecific LBP.
- Trial name
- NCT07215286
- Testing
- Loaded-SNAG, Unloaded-SNAG
- Where
- Saudi Arabia
- Volunteers
- 59 people
- Sponsor
- University of Hail
Chronic Low-back Pain
Feasibility, Effectiveness, and Patient Experience of Online Acceptance and Commitment Therapy Plus Exercises for Older People With Chronic Low Back Pain
No study has investigated the effects of online ACT on community-dwelling older adults. Given that clinical practice guidelines have recommended exercise therapy for treating people with CLBP, a combination of ACT and exercise…
- Trial name
- NCT06576414
- Testing
- Acceptance and Commitment Therapy (ACT), back exercise, back care education
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Chronic Low-back Pain (cLBP)
Core Muscle Training in Patients With Chronic Mechanical Low Back Pain
The goal of this study is to train core muscles in patients with chronic low back pain, the researchers will compar between the effect of suspension exercise core muscle training and pressure biofeed back core muscle training
- Trial name
- NCT07448766
- Testing
- suspension execises, pressure biofeedback training, advices
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University