Clinical trials: Chronic Musculoskeletal Pain
Osteoarthritis, Knee, Osteo Arthritis Knee
Study to Evaluate Resiniferatoxin in Patients With Knee Osteoarthritis Whose Total Knee Replacement Surgery is Delayed
Efficacy and safety study of resiniferatoxin versus placebo to manage pain in patients with knee osteoarthritis whose TKR surgery is delayed
- Conditions
- Osteoarthritis, Knee, Osteo Arthritis Knee, Knee Pain Chronic
- Trial name
- NCT04386980
- Testing
- Resiniferatoxin
- Sponsor
- Sorrento Therapeutics, Inc.
Osteoarthritis of the Knee
Investigation of 1.2% Sodium Hyaluronate for Treatment of Painful Chronic Osteoarthritis of the Knee
Subjects with chronic osteoarthritis of the knee will be assigned to receive an injection of either 1.2% sodium hyaluronate or buffered saline to evaluate its effectiveness and safety for 26 weeks.
- Trial name
- NCT00988091
- Testing
- 1.2% Sodium Hyaluronate, Buffered Saline
- Where
- 34 sites in United States
- Volunteers
- 596 people
- Sponsor
- Ferring Pharmaceuticals
Osteoarthritis of the Knee
A Study of Duloxetine (LY248686) in Participants With Chronic Osteoarthritis and Knee Pain in Japan
The main purpose of this study is to evaluate the efficacy of the study drug known as duloxetine in participants with chronic osteoarthritis (OA) and knee pain in Japan.
- Trial name
- NCT02248480
- Testing
- Duloxetine
- Where
- Japan
- Volunteers
- 354 people
- Sponsor
- Eli Lilly and Company
Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee
Safety and Efficacy Study of GRT6005 in Patients With Osteoarthritis (OA) Knee Pain
The purpose of this study is to evaluate the safety and efficacy of GRT6005 compared to placebo in patients with moderate to severe chronic pain due to osteoarthritis (OA) of the knee.
- Trial name
- NCT01709214
- Testing
- Cebranopadol (GRT6005) Low-Dose Range, Cebranopadol (GRT6005) High-Dose Range, Oxycodone CR
- Where
- 83 sites in United States
- Volunteers
- 619 people
- Sponsor
- Tris Pharma, Inc.
Chronic Pain
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time
The primary objective of this study is to evaluate efficacy of hydrocodone extended-release (ER) tablets compared with placebo in alleviating moderate to severe pain in patients with osteoarthritis or low back pain as assessed by…
- Trial name
- NCT01240863
- Testing
- Hydrocodone ER
- Where
- 73 sites in United States
- Volunteers
- 391 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Bone Marrow Edema, Knee Pain Chronic
Subchondroplasty® Knee RCT
This is a multi-center, prospective, single-blinded, two-arm study, randomized to include approximately 134 subjects treated with Subchondroplasty (SCP) + Arthroscopy and 67 subjects with arthroscopy alone.
- Conditions
- Bone Marrow Edema, Knee Pain Chronic, Knee Osteoarthritis, Osteoarthritis, Knee
- Trial name
- PRESERVE Knee (NCT03112200)
- Testing
- Subchondroplasty with Arthroscopy, Arthroscopy Alone
- Where
- 13 sites in United States, Canada
- Volunteers
- 131 people
- Sponsor
- Zimmer Biomet
Fibromyalgia, Pain, Chronic
Effectiveness of the Sana Device on Fibromyalgia Symptoms
This is study designed to confirm the effectiveness of the Sana Device in patients with pain due to fibromyalgia on quality of life as measured by the Fibromyalgia Impact Questionnaire Revised (FIQR).
- Conditions
- Fibromyalgia, Pain, Chronic, Quality of Life
- Trial name
- NCT05394610
- Testing
- Sana Device, Sana Device (Control)
- Sponsor
- Sana Health
Chronic Musculoskeletal Disease
Efficacy of "Pain Gear" in Patients With Chronic Musculoskeletal Pain
The current study was designed to evaluate the effectiveness and safety of the device in the common areas of the body affected by different causes of musculoskeletal pain in Vietnamese population in real life situation.
- Trial name
- NCT02974023
- Testing
- Pain Gear
- Sponsor
- PharmEvo Pvt Ltd
Osteoarthritis of the Shoulder
SUPARTZ Versus Placebo in Osteoarthritis of the Shoulder
This clinical trial is to determine the safety and effectiveness of three injections of SUPARTZ (sodium hyaluronate) compared with phosphate buffered saline (PBS) for the treatment of glenohumeral osteoarthritis of the shoulder.
- Trial name
- NCT00479687
- Testing
- SUPARTZ®, Phosphate Buffered Saline
- Volunteers
- 300 people
- Sponsor
- Bioventus LLC
Osteoarthritis, Knee, Osteoarthritis, Hip
A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform
Post-market prospective, multi-center longitudinal study to determine if mobile application-guided education and exercise paired with accurate and sensitive activity monitoring, captured from consumer wearables, can provide a…
- Trial name
- NCT03737149
- Testing
- mymobility with Apple Watch
- Where
- 30 sites in United States, Australia and 2 more
- Volunteers
- 6,559 people
- Sponsor
- Zimmer Biomet