Clinical trials: Chronic Nephropathy
Secondary Hyperparathyroidism
A Study to Assess the Efficacy and Safety of Paricalcitol in the Treatment of Chronic Kidney Disease With Secondary Hyperparathyroidism
The study is being conducted to evaluate the efficacy, and safety of Paricalcitol for secondary hyperparathyroidism with stage 3 and stage 4 chronic kidney disease in adults.
- Trial name
- NCT04994080
- Testing
- Paricalcitol
- Volunteers
- 84 people
- Sponsor
- Chengdu Suncadia Medicine Co., Ltd.
Covid19, AKI
Global Assessment of Acute and Chronic Kidney Disease Incidence and Outcomes in Patients With COVID-19 Infection
The coronavirus (COVID-19) pandemic has created a significant strain on health care resources across the world for managing critically ill patients.
- Conditions
- Covid19, AKI, CKD, ESRD
- Trial name
- NCT04491227
- Where
- 12 sites in United States, Bolivia and 4 more
- Volunteers
- 2,000 people
- Sponsor
- University of California, San Diego
End-Stage Renal Disease
Anti-Cytokine Therapy for Hemodialysis InflammatION
Anti-Cytokine Therapy for Hemodialysis InflammatION (ACTION) is a phase II multi-center study to evaluate the safety and tolerability of anakinra, an IL-1 receptor antagonist, for patients treated with maintenance hemodialysis.
- Trial name
- ACTION (NCT03141983)
- Testing
- Anakinra
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Pennsylvania
Kidney Transplantation, Chronic Kidney Disease
Calcineurin Free Immunosuppression in Renal Transplant Recipients
The main purpose of this study is to obtain preliminary information on the efficacy, safety and cost of two regimens, Rapamycin / MMF / steroid therapy and Cyclosporine A Neoral / MMF / steroid therapy, used in the prevention of…
- Trial name
- NCT00812123
- Testing
- Sirolimus, Cyclosporine A, Prednisone
- Where
- Switzerland
- Volunteers
- 127 people
- Sponsor
- University Hospital, Basel, Switzerland
End Stage Renal Disease
Outcomes of Renal Access Arteriovenous Fistulas for Hemodialysis in Patients With Chronic Renal Failure
End stage renal disease cases has increased significantly in the last decade. There are various treatment modalities which are available for the ESRD patients.
- Trial name
- NCT04386954
- Testing
- observational study
- Where
- India
- Volunteers
- 52 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Type 2 Diabetes With Renal Manifestations
Predictors of Chronic Kidney Disease Among Type 2 Diabetic Patients in Assiut University Hospitals
Predictors of Chronic Kidney Disease among Type 2 Diabetic Patients in Assiut University Hospitals.
- Trial name
- Ckd&dm (NCT05847400)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Renal Failure, Chronic Kidney Disease
Clinical Performance of the Therapy Option FlexPoint of the PD Cycler Sleep•Safe Harmony
Analysis and comparison of treatments with and without the FlexPoint technology (flexible volume and dwell time management) of the PD cycler sleep•safe harmony
- Trial name
- FlexPoint (NCT06390592)
- Testing
- PD cycler
- Volunteers
- 24 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Acute Rejection (AR) of Transplanted Kidney, Chronic Allograft Nephropathy (CAN)
Proteogenomic Monitoring and Assessment of Kidney Transplant Recipients
Chronic Allograft Nephropathy (CAN)/Interstitial fibrosis and Tubular Atrophy (IFTA) is responsible for most kidney transplant failures. CAN/IFTA on a 3 month kidney biopsy strongly predicts graft survival long term.
- Conditions
- Acute Rejection (AR) of Transplanted Kidney, Chronic Allograft Nephropathy (CAN), Interstitial Fibrosis (IF), Tubular Atrophy (TA)
- Trial name
- Mini-Kidney (NCT01531257)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Northwestern University
Chronic Kidney Diseases, Acute Coronary Syndrome
Study Comparing Treatment Effectiveness of Guideline Indicated APT for ACS in Patients With CKD
To compare clinical outcomes in patients with chronic kidney disease (CKD) presenting with an acute coronary syndrome (ACS) treated with clopidogrel or ticagrelor (both FDA approved and guideline indicated drugs for treating…
- Trial name
- CPRS-CKD (NCT03150667)
- Testing
- Ticagrelor, Clopidogrel
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- North Texas Veterans Healthcare System
Chronic Kidney Disease, Proteinuria
The Effect of Various Types of the Renin-angiotensin-aldosterone System Blockade on Proteinuria
The main purpose of the study is to compare the effects of three different types of RAAS blockade on 24 hours proteinuria in patients with non-diabetic chronic kidney disease.
- Trial name
- NCT01541267
- Testing
- aliskiren, eplerenon, telmisartan
- Volunteers
- 20 people
- Sponsor
- Medical University of Gdansk
Chronic Kidney Disease, Hyperparathyroidism, Secondary
Safety & Tolerability of Cinacalcet in Pediatric Patients With Chronic Kidney Disease and Secondary Hyperparathyroidism
The primary objective was to characterize corrected serum calcium levels on treatment with cinacalcet in pediatric patients with secondary hyperparathyroidism (HPT).
- Trial name
- NCT01439867
- Testing
- Cinacalcet hydrochloride, Standard of Care
- Where
- 42 sites in United States, Belgium and 11 more
- Volunteers
- 18 people
- Sponsor
- Amgen
Chronic Kidney Disease, Type 1 Diabetes Mellitus
A Study to Learn How Well the Study Treatment Finerenone Works and How Safe it is in People With Long-term Decrease in the Kidneys' Ability to Work Properly (Chronic Kidney Disease) Together With Type 1 Diabetes
Researchers are looking for a better way to treat people with chronic kidney disease (CKD), a progressive decrease in the kidneys' ability to work properly, and type 1 diabetes.
- Trial name
- FINE-ONE (NCT05901831)
- Testing
- Finerenone
- Where
- 79 sites in United States, Canada and 7 more
- Volunteers
- 242 people
- Sponsor
- Bayer
Organic, Including Symptomatic, Mental Disorders, Substance Use
Exploring the Comorbidity Between Mental Disorders and General Medical Conditions
Mental disorders have been shown to be associated with a number of general medical conditions (also referred to as somatic or physical conditions).
- Conditions
- Organic, Including Symptomatic, Mental Disorders, Substance Use, Schizophrenia, Mood [Affective] Disorders
- Trial name
- COMO-GMC (NCT03847753)
- Testing
- Organic Disorders, Substance Use Disorders, Schizophrenia Disorders
- Volunteers
- 5,940,299 people
- Sponsor
- University of Aarhus
Pruritus, Uremia
Gabapentin Versus Loratadine in Uremic Pruritus
The goal of this clinical trial is to compare the efficacy of gabapentin with loratadine in reducing the severity of uremic pruritus in patients of chronic kidney disease and to compare the side effects of both drugs.
- Conditions
- Pruritus, Uremia, Chronic Kidney Diseases
- Trial name
- NCT05750875
- Testing
- Loratadine, Gabapentin
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- King Edward Medical University
Hemodialysis
STUDY OF GLUCOSE IN DIALYSIS WATER WITH REGARD TO BLOOD PRESSURE AND QUALITY OF LIFE
We wanted to test the hypotheses that blood pressure level was lower, that the variability of blood pressure and blood glucose was reduced, and that quality of life was improved when glucose was added to the dialysis fluid.
- Trial name
- NCT00278057
- Testing
- dialysisis with and without glucose in the dialysis
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Regional Hospital Holstebro
Chronic Kidney Diseases, Dialysis; Complications
Cardiac Tissue Sodium Assessment in CKD Patients Using Sodium MRI
Chronic kidney disease (CKD) is prevalent worldwide and affects around 10% of people living in developed health economies. As the kidney loses its function in patients with CKD, the kidneys are unable to filter toxins out of the…
- Conditions
- Chronic Kidney Diseases, Dialysis; Complications, Sodium Retention
- Trial name
- NCT04848636
- Testing
- Cardiac Sodium and Proton MRI
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Polycystic Kidney Diseases
Everolimus on CKD Progression in ADPKD Patients
The study will evaluate whether the administration of everolimus (1.5 mg/day) can slow down the progression of CKD in ADPKD patients.
- Trial name
- NCT01009957
- Testing
- Everolimus
- Where
- 7 sites in Italy
- Volunteers
- 71 people
- Sponsor
- A. Manzoni Hospital
Diabetic Kidney Disease, Diabetic Nephropathy
A Study in Participants With Diabetic Kidney Disease
The purpose of this study is to determine if LY2382770 is safe and effective at protecting kidney function in participants with kidney disease due to diabetes.
- Conditions
- Diabetic Kidney Disease, Diabetic Nephropathy, Diabetic Glomerulosclerosis
- Trial name
- NCT01113801
- Testing
- LY2382770
- Where
- 78 sites in United States, Australia and 5 more
- Volunteers
- 417 people
- Sponsor
- Eli Lilly and Company
Polycystic Kidney Disease
Evaluation of Gut Bacteria in Patients With Polycystic Kidney Disease
Gut microbes can influence numerous aspects of human biology. Alterations in the function and composition of gut microbial flora (gut microbiota ) have been linked to inflammatory bowel disease, chronic inflammation…
- Trial name
- NCT02142101
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
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